Lista de obras - Phillip I Bird - Dominio Público Uruguay

A Novel Serpin Regulatory Mechanism: SerpinB9 IS REVERSIBLY INHIBITED BY VICINAL DISULFIDE BOND FORMATION IN THE REACTIVE CENTER LOOP

artículo científico publicado en 2015

A Renaissance in Understanding the Multiple and Diverse Functions of Granzymes?

artículo científico publicado en 2008

A central role for Bid in granzyme B-induced apoptosis

artículo científico publicado en 2004

A common fold mediates vertebrate defense and bacterial attack

artículo científico publicado en 2007

A functional genomics screen identifies PCAF and ADA3 as regulators of human granzyme B-mediated apoptosis and Bid cleavage.

scientific article published on 24 January 2014

A natural genetic variant of granzyme B confers lethality to a common viral infection

artículo científico publicado en 2014

A retained selection cassette increases reporter gene expression without affecting tissue distribution in SPI3 knockout/GFP knock-in mice

article

A retinoic acid/cAMP-responsive enhancer containing a cAMP responsive element is required for the activation of the mouse thrombomodulin-encoding gene in differentiating F9 cells

article

A role for granzyme M in TLR4-driven inflammation and endotoxicosis.

artículo científico publicado en 2010

A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes

artículo científico publicado en 1998

A transgenic zebrafish model of hepatocyte function in human Z α1-antitrypsin deficiency

artículo científico publicado en 2019

A vector, pSHT, for the expression and secretion of protein domains in mammalian cells

artículo científico publicado en 1992

A versatile monoclonal antibody specific to human SERPINB5

artículo científico publicado en 2012

Absence of SERPINB6A causes sensorineural hearing loss with multiple histopathologies in the mouse inner ear.

artículo científico publicado en 2013

Alpha1A- and alpha1B-adrenoceptors are the major subtypes in human saphenous vein.

artículo científico publicado en 2001

An Essential Role of Maspin in Embryogenesis and Tumor Suppression-Letter.

artículo científico publicado en 2017

An unexpected incompatibility interaction between two plasmids belonging to the I compatibility complex

artículo científico publicado en 1982

Analysis of Perforin Assembly by Quartz Crystal Microbalance Reveals a Role for Cholesterol and Calcium-independent Membrane Binding

artículo científico publicado en 2015

Analysis of the evolution of granule associated serine proteases of immune defence (GASPIDs) suggests a revised nomenclature.

artículo científico publicado en 2014

Analysis of the incompatibility determinants of I-complex plasmids.

artículo científico publicado en 1988

Analysis of vertebrate genomes suggests a new model for clade B serpin evolution.

artículo científico publicado en 2005

Antihemostatic Activity of Human Granzyme B Mediated by Cleavage of von Willebrand Factor

artículo científico publicado en 2008

Are all granzymes cytotoxic in vivo?

artículo científico publicado en 2014

Assembly of streptolysin O pores assessed by quartz crystal microbalance and atomic force microscopy provides evidence for the formation of anchored but incomplete oligomers

article

Blessing or curse? Proteomics in granzyme research

artículo científico

Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity.

artículo científico publicado en 2008

Bone morphogenetic protein/retinoic acid inducible neural-specific protein (brinp) expression during Danio rerio development

artículo científico publicado en 2015

Brinp1(-/-) mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density

artículo científico publicado en 2016

Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation

scientific article published on 01 June 2019

Cathepsin H is an additional convertase of pro-granzyme B

artículo científico publicado en 2010

Cationic sites on granzyme B contribute to cytotoxicity by promoting its uptake into target cells

artículo científico publicado en 2005

Characterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea.

artículo científico publicado en 2016

Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1)

artículo científico publicado en 2002

Chromosomal Mapping of the Gene (PI9) Encoding the Intracellular Serpin Proteinase Inhibitor 9 to 6p25 by Fluorescencein SituHybridization

article

Chromosomal mapping of the human proteinase inhibitor 6 (PI6) gene to 6p25 by fluorescence in situ hybridization

artículo científico publicado en 1995

Cloning and characterising an unusual perforin from chicken (Gallus gallus) ⬇️

artículo científico publicado el 13 de mayo de 2013

Cloning and sequencing of a cDNA encoding the murine vitamin K-dependent protein S.

artículo científico publicado en 1994

Comparison of Human Chromosome 6p25 with Mouse Chromosome 13 Reveals a Greatly Expanded Ov-Serpin Gene Repertoire in the Mouse

article

Conservation of the extended substrate specificity profiles among homologous granzymes across species

artículo científico publicado en 2013

Control of granzymes by serpins.

artículo científico publicado en 2009

Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis

artículo científico publicado en 2006

Demonstration of a third incompatibility function on plasmids already incompatible with group P and group I plasmids

artículo científico publicado en 1983

Detection of Human and Mouse Granzyme B Activity in Cell Extracts

scientific article published on 01 January 2012

Distinct membrane and cytosolic forms of inositol polyphosphate 5-phosphatase II. Efficient membrane localization requires two discrete domains

scientific journal article

Distribution of serine proteinase inhibitor, clade B, member 6 (Serpinb6) in the adult mouse brain

artículo científico publicado en 2002

Effects of annexin V on the activity of the anticoagulant proteins C and S

scientific article published on 01 February 1993

Elucidation of the substrate specificity of the C1s protease of the classical complement pathway

artículo científico publicado en 2005

Elucidation of the substrate specificity of the MASP-2 protease of the lectin complement pathway and identification of the enzyme as a major physiological target of the serpin, C1-inhibitor

artículo científico publicado en 2007

Endolysosomal proteases and their inhibitors in immunity.

scientific article published on December 2009

Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization

artículo científico publicado en 2017

Epigenetic heterochromatin markers distinguish terminally differentiated leukocytes from incompletely differentiated leukemia cells in human blood.

artículo científico publicado en 2006

Expression, purification and characterization of recombinant Z alpha(1)-antitrypsin--the most common cause of alpha(1)-antitrypsin deficiency.

artículo científico publicado en 2009

Gene structure, chromosomal localization, and expression of the murine homologue of human proteinase inhibitor 6 (PI-6) suggests divergence of PI-6 from the ovalbumin serpins

scientific journal article

Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway

artículo científico publicado en 2017

Granzyme B leakage-induced cell death: a new type of activation-induced natural killer cell death.

artículo científico publicado en 2003

Granzyme B promotes cytotoxic lymphocyte transmigration via basement membrane remodeling.

artículo científico publicado en 2014

Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737

artículo científico publicado en 2012

Granzyme K Expressed by Classically Activated Macrophages Contributes to Inflammation and Impaired Remodeling

artículo científico publicado en 2018

Granzyme K-deficient mice show no evidence of impaired antiviral immunity.

artículo científico publicado en 2017

Human Ovalbumin Serpin Evolution: Phylogenic Analysis, Gene Organization, and Identification of New PI8-Related Genes Suggest That Two Interchromosomal and Several Intrachromosomal Duplications Generated the Gene Clusters at 18q21–q23 and 6p25

article

Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis.

artículo científico publicado en 2004

Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis

artículo científico publicado en 2003

Identification of AHNAK as a novel autoantigen in systemic lupus erythematosus

artículo científico publicado en 2002

Identification of Serpinb6b as a species-specific mouse granzyme A inhibitor suggests functional divergence between human and mouse granzyme A.

artículo científico publicado en 2014

Interaction of annexin V and platelets: Effects on platelet function and protein S binding

artículo científico publicado en 1993

Interaction of the nuclear localizing cytolytic granule serine protease granzyme B with importin alpha or beta: modulation by the serpin inhibitor PI-9.

artículo científico publicado en 2005

Intercellular communication via the endo-lysosomal system: Translocation of granzymes through membrane barriers ⬇️

artículo científico publicado el 6 de junio de 2011

Intracellular Production of Recombinant Serpins in Yeast

article

Maspin (SERPINB5) is an obligate intracellular serpin

artículo científico publicado en 2010

Maspin is not required for embryonic development or tumour suppression

artículo científico publicado en 2014

Mechanisms of serpin dysfunction in disease.

artículo científico publicado en 2006

Mice Lacking Brinp2 or Brinp3, or Both, Exhibit Behaviors Consistent with Neurodevelopmental Disorders.

artículo científico publicado en 2016

Modulation and Redistribution of Proteinase Inhibitor 8 (Serpinb8) during Kidney Regeneration

scientific article published on 01 January 2006

Modulation of the granzyme B inhibitor proteinase inhibitor 9 (PI-9) by activation of lymphocytes and monocytes in vitro and by Epstein-Barr virus and bacterial infection.

artículo científico publicado en 2006

Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis

artículo científico publicado en 2013

NK cell intrinsic regulation of MIP-1α by granzyme M

artículo científico publicado en 2014

Neurodevelopmental MACPFs: The vertebrate astrotactins and BRINPs

artículo científico publicado en 2017

Nucleolar and cytoplasmic localization of annexin V.

artículo científico publicado en 1992

Nucleophosmin is cleaved and inactivated by the cytotoxic granule protease granzyme M during natural killer cell-mediated killing

artículo científico publicado en 2008

Perforin evolved from a gene duplication of MPEG1, followed by a complex pattern of gene gain and loss within Euteleostomi

artículo científico publicado en 2012

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

artículo científico publicado en 2013

Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction

artículo científico publicado en 2001

Posttranslational translocation of influenza virus hemagglutinin across microsomal membranes

artículo científico publicado en 1987

Predicting serpin/protease interactions

artículo científico publicado en 2011

Preface

Preliminary analysis of the incompatibility determinant of a group B miniplasmid

artículo científico publicado en 1985

Probing the efficiency of proteolytic events by positional proteomics

artículo científico publicado en 2010

Production and characterization of recombinant human proteinase inhibitor 6 expressed in Pichia pastoris

artículo científico publicado en 1995

Production of recombinant serpins in Escherichia coli

artículo científico publicado en 2004

Production of serpins using yeast expression systems

article

Proteinase inhibitor 6 (PI-6) expression in human skin: induction of PI-6 and a PI-6/proteinase complex during keratinocyte differentiation

artículo científico publicado en 1998

Proteinase inhibitor 8 Map position 18q21.3.

scientific article published on 01 June 1997

RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation

artículo científico publicado en 2017

Recombinant caspase-3 expressed in Pichia pastoris is fully activated and kinetically indistinguishable from the native enzyme

artículo científico publicado en 1997

Regulation of pro-apoptotic leucocyte granule serine proteinases by intracellular serpins.

artículo científico publicado en 1999

Reply to: "Differential expression of serpins may selectively license distinct granzyme B functions including antigen cross-presentation".

artículo científico publicado en 2017

Role of countertranscript RNA in the copy number control system of an IncB miniplasmid.

artículo científico publicado en 1989

SerpinB6 is an inhibitor of kallikrein-8 in keratinocytes

artículo científico publicado en 2007

Serpinb9 is a marker of antigen cross-presenting dendritic cells.

artículo científico publicado en 2016

Serpins 2005 - fun between the beta-sheets. Meeting report based upon presentations made at the 4th International Symposium on Serpin Structure, Function and Biology (Cairns, Australia).

artículo científico publicado en 2005

Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems

artículo científico publicado en 2010

Serpins flex their muscle: II. Structural insights into target peptidase recognition, polymerization, and transport functions

artículo científico publicado en 2010

Serpins: finely balanced conformational traps

artículo científico publicado en 2002

Structure of granzyme C reveals an unusual mechanism of protease autoinhibition

artículo científico publicado en 2009

Substrate specificities of the granzyme tryptases A and K.

artículo científico publicado en 2014

The MACPF/CDC family of pore-forming toxins

artículo científico publicado en 2008

The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1

artículo científico publicado en 2019

The effects of exosite occupancy on the substrate specificity of thrombin

artículo científico publicado en 2009

The granzyme B inhibitor, PI-9, is differentially expressed during placental development and up-regulated in hydatidiform moles.

artículo científico publicado en 2005

The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix

artículo científico publicado en 2005

The human serpin proteinase inhibitor-9 self-associates at physiological temperatures

artículo científico publicado en 2004

The major human and mouse granzymes are structurally and functionally divergent

artículo científico publicado en 2006

The perforin pore facilitates the delivery of cationic cargos

scientific article published on 20 February 2014

The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

artículo científico publicado en 2001

The structural basis for membrane binding and pore formation by lymphocyte perforin

artículo científico publicado en 2010

The use of mini-Gal plasmids for rapid incompatibility grouping of conjugative R plasmids

artículo científico publicado en 1984

Tissue distribution and intracellular localisation of the 75-kDa inositol polyphosphate 5-phosphatase.

artículo científico publicado en 1995

Translocation in yeast and mammalian cells: not all signal sequences are functionally equivalent.

artículo científico publicado en 1987

Uncoupling of translocation across microsomal membranes from biosynthesis of influenza virus hemagglutinin ⬇️

artículo científico publicado el 1 de marzo de 1988

Zebrafish models for nemaline myopathy reveal a spectrum of nemaline bodies contributing to reduced muscle function

artículo científico publicado en 2015

Lista de obras de Phillip I Bird

A Novel Serpin Regulatory Mechanism: SerpinB9 IS REVERSIBLY INHIBITED BY VICINAL DISULFIDE BOND FORMATION IN THE REACTIVE CENTER LOOP

A Renaissance in Understanding the Multiple and Diverse Functions of Granzymes?

A central role for Bid in granzyme B-induced apoptosis

A common fold mediates vertebrate defense and bacterial attack

A functional genomics screen identifies PCAF and ADA3 as regulators of human granzyme B-mediated apoptosis and Bid cleavage.

A natural genetic variant of granzyme B confers lethality to a common viral infection

A retained selection cassette increases reporter gene expression without affecting tissue distribution in SPI3 knockout/GFP knock-in mice

A retinoic acid/cAMP-responsive enhancer containing a cAMP responsive element is required for the activation of the mouse thrombomodulin-encoding gene in differentiating F9 cells

A role for granzyme M in TLR4-driven inflammation and endotoxicosis.

A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes

A transgenic zebrafish model of hepatocyte function in human Z α1-antitrypsin deficiency

A vector, pSHT, for the expression and secretion of protein domains in mammalian cells

A versatile monoclonal antibody specific to human SERPINB5

Absence of SERPINB6A causes sensorineural hearing loss with multiple histopathologies in the mouse inner ear.

Alpha1A- and alpha1B-adrenoceptors are the major subtypes in human saphenous vein.

An Essential Role of Maspin in Embryogenesis and Tumor Suppression-Letter.

An unexpected incompatibility interaction between two plasmids belonging to the I compatibility complex

Analysis of Perforin Assembly by Quartz Crystal Microbalance Reveals a Role for Cholesterol and Calcium-independent Membrane Binding

Analysis of the evolution of granule associated serine proteases of immune defence (GASPIDs) suggests a revised nomenclature.

Analysis of the incompatibility determinants of I-complex plasmids.

Analysis of vertebrate genomes suggests a new model for clade B serpin evolution.

Antihemostatic Activity of Human Granzyme B Mediated by Cleavage of von Willebrand Factor

Are all granzymes cytotoxic in vivo?

Assembly of streptolysin O pores assessed by quartz crystal microbalance and atomic force microscopy provides evidence for the formation of anchored but incomplete oligomers

Blessing or curse? Proteomics in granzyme research

Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity.

Bone morphogenetic protein/retinoic acid inducible neural-specific protein (brinp) expression during Danio rerio development

Brinp1(-/-) mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density

Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation

Cathepsin H is an additional convertase of pro-granzyme B

Cationic sites on granzyme B contribute to cytotoxicity by promoting its uptake into target cells

Characterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea.

Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1)

Chromosomal Mapping of the Gene (PI9) Encoding the Intracellular Serpin Proteinase Inhibitor 9 to 6p25 by Fluorescencein SituHybridization

Chromosomal mapping of the human proteinase inhibitor 6 (PI6) gene to 6p25 by fluorescence in situ hybridization

Cloning and characterising an unusual perforin from chicken (Gallus gallus) ⬇️

Cloning and sequencing of a cDNA encoding the murine vitamin K-dependent protein S.

Comparison of Human Chromosome 6p25 with Mouse Chromosome 13 Reveals a Greatly Expanded Ov-Serpin Gene Repertoire in the Mouse

Conservation of the extended substrate specificity profiles among homologous granzymes across species

Control of granzymes by serpins.

Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis

Demonstration of a third incompatibility function on plasmids already incompatible with group P and group I plasmids

Detection of Human and Mouse Granzyme B Activity in Cell Extracts

Distinct membrane and cytosolic forms of inositol polyphosphate 5-phosphatase II. Efficient membrane localization requires two discrete domains

Distribution of serine proteinase inhibitor, clade B, member 6 (Serpinb6) in the adult mouse brain

Effects of annexin V on the activity of the anticoagulant proteins C and S

Elucidation of the substrate specificity of the C1s protease of the classical complement pathway

Elucidation of the substrate specificity of the MASP-2 protease of the lectin complement pathway and identification of the enzyme as a major physiological target of the serpin, C1-inhibitor

Endolysosomal proteases and their inhibitors in immunity.

Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization

Epigenetic heterochromatin markers distinguish terminally differentiated leukocytes from incompletely differentiated leukemia cells in human blood.

Expression, purification and characterization of recombinant Z alpha(1)-antitrypsin--the most common cause of alpha(1)-antitrypsin deficiency.

Gene structure, chromosomal localization, and expression of the murine homologue of human proteinase inhibitor 6 (PI-6) suggests divergence of PI-6 from the ovalbumin serpins

Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway

Granzyme B leakage-induced cell death: a new type of activation-induced natural killer cell death.

Granzyme B promotes cytotoxic lymphocyte transmigration via basement membrane remodeling.

Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737

Granzyme K Expressed by Classically Activated Macrophages Contributes to Inflammation and Impaired Remodeling

Granzyme K-deficient mice show no evidence of impaired antiviral immunity.

Human Ovalbumin Serpin Evolution: Phylogenic Analysis, Gene Organization, and Identification of New PI8-Related Genes Suggest That Two Interchromosomal and Several Intrachromosomal Duplications Generated the Gene Clusters at 18q21–q23 and 6p25

Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis.

Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis

Identification of AHNAK as a novel autoantigen in systemic lupus erythematosus

Identification of Serpinb6b as a species-specific mouse granzyme A inhibitor suggests functional divergence between human and mouse granzyme A.

Interaction of annexin V and platelets: Effects on platelet function and protein S binding

Interaction of the nuclear localizing cytolytic granule serine protease granzyme B with importin alpha or beta: modulation by the serpin inhibitor PI-9.

Intercellular communication via the endo-lysosomal system: Translocation of granzymes through membrane barriers ⬇️

Intracellular Production of Recombinant Serpins in Yeast

Maspin (SERPINB5) is an obligate intracellular serpin

Maspin is not required for embryonic development or tumour suppression

Mechanisms of serpin dysfunction in disease.

Mice Lacking Brinp2 or Brinp3, or Both, Exhibit Behaviors Consistent with Neurodevelopmental Disorders.

Modulation and Redistribution of Proteinase Inhibitor 8 (Serpinb8) during Kidney Regeneration

Modulation of the granzyme B inhibitor proteinase inhibitor 9 (PI-9) by activation of lymphocytes and monocytes in vitro and by Epstein-Barr virus and bacterial infection.

Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis

NK cell intrinsic regulation of MIP-1α by granzyme M

Neurodevelopmental MACPFs: The vertebrate astrotactins and BRINPs

Nucleolar and cytoplasmic localization of annexin V.

Nucleophosmin is cleaved and inactivated by the cytotoxic granule protease granzyme M during natural killer cell-mediated killing