Lista de obras - Marten F. Snel - Dominio Público Uruguay

A novel conditional Sgsh knockout mouse model recapitulates phenotypic and neuropathic deficits of Sanfilippo syndrome

artículo científico publicado en 2017

A simple method for early age phenotype confirmation using toe tissue from a mouse model of MPS IIIA

artículo científico publicado en 2014

AAVrh10 Vector Corrects Disease Pathology in MPS IIIA Mice and Achieves Widespread Distribution of SGSH in Large Animal Brains

scientific article published on 10 December 2019

Butanolysis derivatization: improved sensitivity in LC-MS/MS quantitation of heparan sulfate in urine from mucopolysaccharidosis patients

artículo científico publicado en 2015

Delivery of therapeutic protein for prevention of neurodegenerative changes: comparison of different CSF-delivery methods

artículo científico publicado en 2014

Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin-fixed paraffin-embedded adenocarcinoma tissue sections

artículo científico publicado en 2009

Determination of the role of injection site on the efficacy of intra-CSF enzyme replacement therapy in MPS IIIA mice

artículo científico publicado en 2015

Developing a multivariable prediction model for functional outcome after reperfusion therapy for acute ischaemic stroke: study protocol for the Targeting Optimal Thrombolysis Outcomes (TOTO) multicentre cohort study

artículo científico publicado en 2020

Disease stage determines the efficacy of treatment of a paediatric neurodegenerative disease

artículo científico publicado en 2014

Early disease course is unaltered in mucopolysaccharidosis type IIIA (MPS IIIA) mice lacking α-synuclein

scientific article published on 25 April 2019

Eukaryotic elongation factor 2 kinase upregulates the expression of proteins implicated in cell migration and cancer cell metastasis

artículo científico publicado en 2017

Evaluation of Disease Lesions in the Developing Canine MPS IIIA Brain

artículo científico publicado en 2018

Evaluation of Small Molecule Drug Uptake in Patient-Derived Prostate Cancer Explants by Mass Spectrometry

scientific article published on 18 October 2019

Evaluation of enzyme dose and dose-frequency in ameliorating substrate accumulation in MPS IIIA Huntaway dog brain

artículo científico publicado en 2014

FAST-IT: Find A Simple Test - In TIA (transient ischaemic attack): a prospective cohort study to develop a multivariable prediction model for diagnosis of TIA through proteomic discovery and candidate lipid mass sp

artículo científico publicado en 2022

Glycosphingolipid analysis in a naturally occurring ovine model of acute neuronopathic Gaucher disease.

artículo científico publicado en 2016

High-spatial resolution matrix-assisted laser desorption ionization imaging analysis of glucosylceramide in spleen sections from a mouse model of Gaucher disease

artículo científico publicado en 2010

Inbred Mouse Populations Exhibit Intergenerational Changes in Intestinal Microbiota Composition and Function Following Introduction to a Facility.

artículo científico publicado en 2017

Low-dose, continual enzyme delivery ameliorates some aspects of established brain disease in a mouse model of a childhood-onset neurodegenerative disorder

artículo científico publicado en 2015

Low-dose, continuous enzyme replacement therapy ameliorates brain pathology in the neurodegenerative lysosomal disorder mucopolysaccharidosis type IIIA.

artículo científico publicado en 2016

Lysosomal N-acetyltransferase interacts with ALIX and is detected in extracellular vesicles

artículo científico publicado en 2018

MALDI-QTOFMS/MS identification of glycoforms from the urine of a CDG patient

artículo científico publicado en 2007

MALDI-ion mobility separation-mass spectrometry imaging of glucose-regulated protein 78 kDa (Grp78) in human formalin-fixed, paraffin-embedded pancreatic adenocarcinoma tissue sections.

artículo científico publicado en 2009

Matrix-assisted laser desorption/ionization-ion mobility separation-mass spectrometry imaging of vinblastine in whole body tissue sections

artículo científico publicado en 2008

Neuronal-specific impairment of heparan sulfate degradation in Drosophila reveals pathogenic mechanisms for Mucopolysaccharidosis type IIIA.

artículo científico publicado en 2018

Novel molecular tumour classification using MALDI-mass spectrometry imaging of tissue micro-array

artículo científico publicado en 2010

On-tissue protein identification and imaging by MALDI-ion mobility mass spectrometry.

artículo científico publicado en 2009

Parallel post-source decay for increasing protein identification confidence levels from 2-D gels.

artículo científico publicado en 2008

Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis

artículo científico publicado en 2020

Slow, continuous enzyme replacement via spinal CSF in dogs with the paediatric-onset neurodegenerative disease, MPS IIIA.

artículo científico publicado en 2016

Small molecule MALDI MS imaging: Current technologies and future challenges.

artículo científico publicado en 2016

Synthesis and mass spectrometric analysis of disaccharides from methanolysis of heparan sulfate

artículo científico publicado en 2018

Synthetic Disaccharide Standards Enable Quantitative Analysis of Stored Heparan Sulfate in MPS IIIA Murine Brain Regions

scientific article published on 18 July 2019

Lista de obras de Marten F. Snel

A novel conditional Sgsh knockout mouse model recapitulates phenotypic and neuropathic deficits of Sanfilippo syndrome

A simple method for early age phenotype confirmation using toe tissue from a mouse model of MPS IIIA

AAVrh10 Vector Corrects Disease Pathology in MPS IIIA Mice and Achieves Widespread Distribution of SGSH in Large Animal Brains

Butanolysis derivatization: improved sensitivity in LC-MS/MS quantitation of heparan sulfate in urine from mucopolysaccharidosis patients

Delivery of therapeutic protein for prevention of neurodegenerative changes: comparison of different CSF-delivery methods

Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin-fixed paraffin-embedded adenocarcinoma tissue sections

Determination of the role of injection site on the efficacy of intra-CSF enzyme replacement therapy in MPS IIIA mice

Developing a multivariable prediction model for functional outcome after reperfusion therapy for acute ischaemic stroke: study protocol for the Targeting Optimal Thrombolysis Outcomes (TOTO) multicentre cohort study

Disease stage determines the efficacy of treatment of a paediatric neurodegenerative disease

Early disease course is unaltered in mucopolysaccharidosis type IIIA (MPS IIIA) mice lacking α-synuclein

Eukaryotic elongation factor 2 kinase upregulates the expression of proteins implicated in cell migration and cancer cell metastasis

Evaluation of Disease Lesions in the Developing Canine MPS IIIA Brain

Evaluation of Small Molecule Drug Uptake in Patient-Derived Prostate Cancer Explants by Mass Spectrometry

Evaluation of enzyme dose and dose-frequency in ameliorating substrate accumulation in MPS IIIA Huntaway dog brain

FAST-IT: <i>F</i>ind <i>A S</i>imple <i>T</i>est - <i>I</i>n <i>T</i>IA (transient ischaemic attack): a prospective cohort study to develop a multivariable prediction model for diagnosis of TIA through proteomic discovery and candidate lipid mass sp

Glycosphingolipid analysis in a naturally occurring ovine model of acute neuronopathic Gaucher disease.

High-spatial resolution matrix-assisted laser desorption ionization imaging analysis of glucosylceramide in spleen sections from a mouse model of Gaucher disease

Inbred Mouse Populations Exhibit Intergenerational Changes in Intestinal Microbiota Composition and Function Following Introduction to a Facility.

Low-dose, continual enzyme delivery ameliorates some aspects of established brain disease in a mouse model of a childhood-onset neurodegenerative disorder

Low-dose, continuous enzyme replacement therapy ameliorates brain pathology in the neurodegenerative lysosomal disorder mucopolysaccharidosis type IIIA.

Lysosomal N-acetyltransferase interacts with ALIX and is detected in extracellular vesicles

MALDI-QTOFMS/MS identification of glycoforms from the urine of a CDG patient

MALDI-ion mobility separation-mass spectrometry imaging of glucose-regulated protein 78 kDa (Grp78) in human formalin-fixed, paraffin-embedded pancreatic adenocarcinoma tissue sections.

Matrix-assisted laser desorption/ionization-ion mobility separation-mass spectrometry imaging of vinblastine in whole body tissue sections

Neuronal-specific impairment of heparan sulfate degradation in Drosophila reveals pathogenic mechanisms for Mucopolysaccharidosis type IIIA.

Novel molecular tumour classification using MALDI-mass spectrometry imaging of tissue micro-array

On-tissue protein identification and imaging by MALDI-ion mobility mass spectrometry.

Parallel post-source decay for increasing protein identification confidence levels from 2-D gels.

Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis

Slow, continuous enzyme replacement via spinal CSF in dogs with the paediatric-onset neurodegenerative disease, MPS IIIA.

Small molecule MALDI MS imaging: Current technologies and future challenges.

Synthesis and mass spectrometric analysis of disaccharides from methanolysis of heparan sulfate

Synthetic Disaccharide Standards Enable Quantitative Analysis of Stored Heparan Sulfate in MPS IIIA Murine Brain Regions