Lista de obras - Hiromi Sakai - Dominio Público Uruguay

A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors

artículo científico publicado en 2011

A transient inflammatory reaction in the lung after experimental hemorrhagic shock and resuscitation with a hemoglobin-vesicles solution compared with rat RBC transfusion.

artículo científico publicado en 2009

Academia-Industry Collaboration in Blood Substitute Development: Issues, Case Histories and a Proposal

article

Acute 40 percent exchange-transfusion with hemoglobin-vesicles (HbV) suspended in recombinant human serum albumin solution: degradation of HbV and erythropoiesis in a rat spleen for 2 weeks

artículo científico publicado en 2006

Acute 40% exchange-transfusion with hemoglobin-vesicles in a mouse pneumonectomy model.

artículo científico publicado en 2017

Alteration in the pharmacokinetics of hemoglobin-vesicles in a rat model of chronic liver cirrhosis is associated with Kupffer cell phagocyte activity

artículo científico publicado en 2010

An automated method for cell-free layer width determination in small arterioles

artículo científico publicado en 2011

Analysis of Dimeric αβ Subunit Exchange between PEGylated and Native Hemoglobins (α2β2 Tetramer) in an Equilibrated State by Intramolecular ββ-Cross-Linking

artículo científico publicado en 2018

Antioxidative Pseudoenzymatic Mechanism of NAD(P)H Coexisting with Oxyhemoglobin for Suppressed Methemoglobin Formation

scientific article published on 28 February 2019

Application of Perfusate With Human-Derived Oxygen Carrier Solution Under Subnormothermic Machine Perfusion for Donation After Cardiac Death Liver Grafts in Pigs

artículo científico publicado en 2018

Artificial oxygen carriers rescue placental hypoxia and improve fetal development in the rat pre-eclampsia model

artículo científico publicado en 2015

Artificial oxygen carriers, hemoglobin vesicles and albumin-hemes, based on bioconjugate chemistry

scientific article published on 10 February 2009

Biocompatibility of HbV: Liposome-Encapsulated Hemoglobin Molecules-Liposome Effects on Immune Function.

artículo científico publicado en 2017

Biocompatibility study of hemoglobin vesicles, cellular-type artificial oxygen carriers, with human umbilical cord hematopoietic stem/progenitor cells using an in vitro expansion system.

artículo científico publicado en 2009

Biomimetic carbon monoxide delivery based on hemoglobin vesicles ameliorates acute pancreatitis in mice via the regulation of macrophage and neutrophil activity

artículo científico publicado en 2018

Capillary blood flow during severe hemodilution observed by a noninvasive transcutaneous technique using flash epi-illumination.

artículo científico publicado en 2002

Carbon monoxide-bound hemoglobin vesicles ameliorate multiorgan injuries induced by severe acute pancreatitis in mice by their anti-inflammatory and antioxidant properties

artículo científico publicado en 2016

Carbon monoxide-bound hemoglobin-vesicles for the treatment of bleomycin-induced pulmonary fibrosis.

artículo científico publicado en 2014

Cardiopulmonary hemodynamic responses to the small injection of hemoglobin vesicles (artificial oxygen carriers) in miniature pigs

artículo científico publicado en 2012

Chapter 19 Hemoglobin-Vesicles as an Artificial Oxygen Carrier

artículo científico publicado en 2009

Characteristics of Hb-vesicles and encapsulation procedure

artículo científico publicado en 1994

Characteristics of bovine hemoglobin as a potential source of hemoglobin-vesicles for an artificial oxygen carrier.

artículo científico publicado en 2002

Complete deoxygenation from a hemoglobin solution by an electrochemical method and heat treatment for virus inactivation.

artículo científico publicado en 2002

Constriction of resistance arteries determines l-NAME-induced hypertension in a conscious hamster model.

artículo científico publicado en 2000

Convenient method to purify hemoglobin

scientific article published on 01 January 1994

Detection of lipopolysaccharide in hemoglobin-vesicles by Limulus amebocyte lysate test with kinetic-turbidimetric gel clotting analysis and pretreatment of surfactant.

artículo científico publicado en 2004

Effect of the cellular-type artificial oxygen carrier hemoglobin vesicle as a resuscitative fluid for prehospital treatment: experiments in a rat uncontrolled hemorrhagic shock model

artículo científico publicado en 2012

Effects of hemoglobin vesicles, a liposomal artificial oxygen carrier, on hematological responses, complement and anaphylactic reactions in rats

artículo científico publicado en 2007

Effects of poly(ethyleneglycol)-modified hemoglobin vesicles on agonist-induced platelet aggregation and RANTES release in vitro.

artículo científico publicado en 2001

Efficacy of Resuscitative Transfusion With Hemoglobin Vesicles in the Treatment of Massive Hemorrhage in Rabbits With Thrombocytopenic Coagulopathy and Its Effect on Hemostasis by Platelet Transfusion

artículo científico publicado en 2018

Encapsulation of concentrated hemoglobin solution in phospholipid vesicles retards the reaction with NO, but not CO, by intracellular diffusion barrier

artículo científico publicado en 2007

Evaluation of a new type of nano-sized carbon monoxide donor on treating mice with experimentally induced colitis.

artículo científico publicado en 2016

Fluid resuscitation of hemorrhagic shock with hemoglobin vesicles in Beagle dogs: pilot study.

artículo científico publicado en 2012

Fluid resuscitation with hemoglobin vesicles prevents Escherichia coli growth via complement activation in a hemorrhagic shock rat model.

artículo científico publicado en 2011

Fluid resuscitation with hemoglobin-vesicle solution does not increase hypoxia or inflammatory responses in moderate hemorrhagic shock

artículo científico publicado en 2006

Gas bioengineering using hemoglobin-vesicles for versatile clinical applications.

artículo científico publicado en 2011

Haemodynamics and oxygen tension in the microcirculation of ischaemic skin flaps after neural blockade and haemodilution.

artículo científico publicado en 1999

Hemoglobin Vesicles prolong the time to circulatory collapse in rats during apnea

artículo científico publicado en 2017

Hemoglobin encapsulation in vesicles retards NO and CO binding and O2 release when perfused through narrow gas-permeable tubes.

artículo científico publicado en 2009

Hemoglobin vesicles containing methemoglobin and L-tyrosine to suppress methemoglobin formation in vitro and in vivo

artículo científico publicado en 2006

Hemoglobin vesicles improve wound healing and tissue survival in critically ischemic skin in mice

scientific article published on 02 July 2009

Hemoglobin vesicles reduce hypoxia-related inflammation in critically ischemic hamster flap tissue

artículo científico publicado en 2007

Hemoglobin vesicles, polyethylene glycol (PEG)ylated liposomes developed as a red blood cell substitute, do not induce the accelerated blood clearance phenomenon in mice

artículo científico publicado en 2009

Hemoglobin-vesicles as a transfusion alternative.

artículo científico publicado en 2006

Hemoglobin-vesicles suspended in recombinant human serum albumin for resuscitation from hemorrhagic shock in anesthetized rats.

artículo científico publicado en 2004

Hemorrhagic shock resuscitation with an artificial oxygen carrier, hemoglobin vesicle, maintains intestinal perfusion and suppresses the increase in plasma tumor necrosis factor-alpha

artículo científico publicado en 2004

Hepatically-metabolized and -excreted artificial oxygen carrier, hemoglobin vesicles, can be safely used under conditions of hepatic impairment.

artículo científico publicado en 2010

Hidden Antioxidative Functions of Reduced Nicotinamide Adenine Dinucleotide Coexisting with Hemoglobin

artículo científico publicado en 2017

Histopathological changes of rat brain after direct injection of Hb-vesicles (artificial oxygen carriers) and neurological impact in an intracerebral hemorrhage model.

artículo científico publicado en 2009

Impact of human-derived hemoglobin based oxygen vesicles as a machine perfusion solution for liver donation after cardiac death in a pig model

artículo científico publicado en 2019

In vivo evaluation of electron mediators for the reduction of methemoglobin encapsulated in liposomes using electron energies produced by red blood cell glycolysis.

artículo científico publicado en 2017

Increased viscosity of hemoglobin-based oxygen carriers retards NO-binding when perfused through narrow gas-permeable tubes

artículo científico publicado en 2010

Influence of erythrocyte aggregation at pathological levels on cell-free marginal layer in a narrow circular tube

artículo científico publicado en 2014

Influence of hemoglobin vesicles, cellular-type artificial oxygen carriers, on human umbilical cord blood hematopoietic progenitor cells in vitro.

artículo científico publicado en 2009

Inhibition effect of aggregation of phospholipid vesicles by incorporation of glycolipids

International Consortium for Development of Hemoglobin-Based Oxygen Carriers, Oxygen Therapeutics and Multifunctional Resuscitation Fluids–A White Paper

article

Intravenous injection of artificial red cells and subsequent dye laser irradiation causes deep vessel impairment in an animal model of port-wine stain

artículo científico publicado en 2018

Is hemoglobin in hemoglobin vesicles infused for isovolemic hemodilution necessary to improve oxygenation in critically ischemic hamster skin?

artículo científico publicado en 2005

Liposomal Artificial Red Blood Cell-Based Carbon Monoxide Donor Is a Potent Renoprotectant against Cisplatin-Induced Acute Kidney Injury

artículo científico publicado en 2021

Liposomal microparticle injection can induce myeloid-derived suppressor cells (MDSC)-like cells in vivo.

artículo científico publicado en 2017

Liposome-encapsulated hemoglobin (hemoglobin-vesicle) is not transferred from mother to fetus at the late stage of pregnancy in the rat model

artículo científico publicado en 2012

Long-Term Stored Hemoglobin-Vesicles, a Cellular Type of Hemoglobin-Based Oxygen Carrier, Has Resuscitative Effects Comparable to That for Fresh Red Blood Cells in a Rat Model with Massive Hemorrhage without Post-Transfusion Lung Injury.

artículo científico publicado en 2016

Mechanism of flocculate formation of highly concentrated phospholipid vesicles suspended in a series of water-soluble biopolymers.

artículo científico publicado en 2009

Metabolism of hemoglobin-vesicles (artificial oxygen carriers) and their influence on organ functions in a rat model.

artículo científico publicado en 2004

Methemoglobin formation in hemoglobin vesicles and reduction by encapsulated thiols

artículo científico publicado en 1997

Microcirculation and NO-CO studies of a natural extracellular hemoglobin developed for an oxygen therapeutic carrier.

artículo científico publicado en 2012

Model mice for Presbyterian hemoglobinopathy (Asn(beta108)-->Lys) confer hemolytic anemia with altered oxygen affinity and instability of Hb

scientific journal article

NO and CO binding profiles of hemoglobin vesicles as artificial oxygen carriers

artículo científico publicado en 2008

New generation of hemoglobin-based oxygen carriers evaluated for oxygenation of critically ischemic hamster flap tissue.

artículo científico publicado en 2005

Normothermic preservation of the rat hind limb with artificial oxygen-carrying hemoglobin vesicles

artículo científico publicado en 2015

One-year observation of Wistar rats after intravenous infusion of hemoglobin-vesicles (artificial oxygen carriers).

artículo científico publicado en 2007

Oxygen affinity of hemoglobin regulates O2 consumption, metabolism, and physical activity

artículo científico publicado en 2002

Oxygen transport by low and normal oxygen affinity hemoglobin vesicles in extreme hemodilution.

artículo científico publicado en 2004

Peculiar flow patterns of RBCs suspended in viscous fluids and perfused through a narrow tube (25 microm).

artículo científico publicado en 2009

Phagocytosis of liposome particles by rat splenic immature monocytes makes them transiently and highly immunosuppressive in ex vivo culture conditions

artículo científico publicado en 2011

Pharmacokinetic study of enclosed hemoglobin and outer lipid component after the administration of hemoglobin vesicles as an artificial oxygen carrier.

artículo científico publicado en 2009

Pharmacokinetics of single and repeated injection of hemoglobin-vesicles in hemorrhagic shock rat model

artículo científico publicado en 2009

Phase separation of polymerized mixed liposomes: analysis of release behavior of entrapped molecules with skeletonization

Photoreduction of methemoglobin by irradiation in the near-ultraviolet region

scientific article published on 01 November 2000

Photosensitizer Effects of Artificial Red Cells on Dye Laser Irradiation in an Animal Model Assuming Port-Wine Stain Treatment.

artículo científico publicado en 2017

Physical properties of hemoglobin vesicles as red cell substitutes

artículo científico publicado en 1996

Physiologic responses to exchange transfusion with hemoglobin vesicles as an artificial oxygen carrier in anesthetized rats: changes in mean arterial pressure and renal cortical tissue oxygen tension.

artículo científico publicado en 1996

Physiological capacity of the reticuloendothelial system for the degradation of hemoglobin vesicles (artificial oxygen carriers) after massive intravenous doses by daily repeated infusions for 14 days.

artículo científico publicado en 2004

Poly(ethylene glycol)-Conjugation and Deoxygenation Enable Long-Term Preservation of Hemoglobin-Vesicles as Oxygen Carriers in a Liquid State

artículo científico publicado en 2000

Poly(ethylene glycol)-conjugated phospholipids in aqueous micellar solutions: hydration, static structure, and interparticle interactions

artículo científico publicado en 2007

Potential New Non-Invasive Therapy Using Artificial Oxygen Carriers for Pre-Eclampsia

artículo científico publicado en 2017

Potential electron mediators to extract electron energies of RBC glycolysis for prolonged in vivo functional lifetime of hemoglobin vesicles

artículo científico publicado en 2015

Present Situation of the Development of Cellular-Type Hemoglobin-Based Oxygen Carrier (Hemoglobin-Vesicles) ⬇️

artículo científico publicado el 1 de septiembre de 2012

Pretreatment of serum containing hemoglobin vesicles (oxygen carriers) to prevent their interference in laboratory tests

artículo científico publicado en 2003

Primary and secondary immune responses to keyhole limpet hemocyanin in rats after infusion of hemoglobin vesicle, an artificial oxygen carrier.

artículo científico publicado en 2013

Prolonged functional life span of artificial red cells in blood circulation by repeated methylene blue injections

artículo científico publicado en 2019

Prolonged oxygen-carrying ability of hemoglobin vesicles by coencapsulation of catalase in vivo

artículo científico publicado en 2003

Purification of concentrated hemoglobin using organic solvent and heat treatment

artículo científico publicado en 1993

Red blood cells donate electrons to methylene blue mediated chemical reduction of methemoglobin compartmentalized in liposomes in blood.

artículo científico publicado en 2014

Reduction of methemoglobin via electron transfer from photoreduced flavin: restoration of O2-binding of concentrated hemoglobin solution coencapsulated in phospholipid vesicles

artículo científico publicado en 2004

Removal of cellular-type hemoglobin-based oxygen carrier (hemoglobin-vesicles) from blood using centrifugation and ultrafiltration

artículo científico publicado en 2011

Repeated injection of high doses of hemoglobin-encapsulated liposomes (hemoglobin vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model

scientific article published on 01 December 2010

Rheological properties of hemoglobin vesicles (artificial oxygen carriers) suspended in a series of plasma-substitute solutions

artículo científico publicado en 2007

Ring-Opening Polymerization of Hemoglobin

artículo científico publicado en 2019

Sodium hydroxide based non-detergent decellularizing solution for rat lung

artículo científico publicado en 2018

Study on the Phase Transition Behavior of Polymerized Liposomes through the Interaction of Diene-Groups in Their Acyl Chains

Subcutaneous microvascular responses to hemodilution with a red cell substitute consisting of polyethyleneglycol-modified vesicles encapsulating hemoglobin.

artículo científico publicado en 1998

Surface modification of hemoglobin vesicles with poly(ethylene glycol) and effects on aggregation, viscosity, and blood flow during 90% exchange transfusion in anesthetized rats

artículo científico publicado en 1997

Swine hemoglobin as a potential source of artificial oxygen carriers, hemoglobin-vesicles.

artículo científico publicado en 2012

Synthesis and physicochemical characterization of a series of hemoglobin-based oxygen carriers: objective comparison between cellular and acellular types

artículo científico publicado en 2000

The Use of Hemoglobin Vesicles for Delivering Medicinal Gas for the Treatment of Intractable Disorders.

artículo científico publicado en 2017

The oxygen carrying capability of hemoglobin vesicles evaluated in rat exchange transfusion models

artículo científico publicado en 1997

The role of luminal factors in the recovery of gastric function and behavioral changes after chronic Helicobacter pylori infection

artículo científico publicado en 2008

Transmembrane Difference in Colloid Osmotic Pressure Affects the Lipid Membrane Fluidity of Liposomes Encapsulating a Concentrated Protein Solution

artículo científico publicado en 2017

What is the major mechanism of slower NO uptake by red blood cells?

artículo científico publicado en 2011

Lista de obras de Hiromi Sakai

A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors

A transient inflammatory reaction in the lung after experimental hemorrhagic shock and resuscitation with a hemoglobin-vesicles solution compared with rat RBC transfusion.

Academia-Industry Collaboration in Blood Substitute Development: Issues, Case Histories and a Proposal

Acute 40 percent exchange-transfusion with hemoglobin-vesicles (HbV) suspended in recombinant human serum albumin solution: degradation of HbV and erythropoiesis in a rat spleen for 2 weeks

Acute 40% exchange-transfusion with hemoglobin-vesicles in a mouse pneumonectomy model.

Alteration in the pharmacokinetics of hemoglobin-vesicles in a rat model of chronic liver cirrhosis is associated with Kupffer cell phagocyte activity

An automated method for cell-free layer width determination in small arterioles

Analysis of Dimeric αβ Subunit Exchange between PEGylated and Native Hemoglobins (α2β2 Tetramer) in an Equilibrated State by Intramolecular ββ-Cross-Linking

Antioxidative Pseudoenzymatic Mechanism of NAD(P)H Coexisting with Oxyhemoglobin for Suppressed Methemoglobin Formation

Application of Perfusate With Human-Derived Oxygen Carrier Solution Under Subnormothermic Machine Perfusion for Donation After Cardiac Death Liver Grafts in Pigs

Artificial oxygen carriers rescue placental hypoxia and improve fetal development in the rat pre-eclampsia model

Artificial oxygen carriers, hemoglobin vesicles and albumin-hemes, based on bioconjugate chemistry

Biocompatibility of HbV: Liposome-Encapsulated Hemoglobin Molecules-Liposome Effects on Immune Function.

Biocompatibility study of hemoglobin vesicles, cellular-type artificial oxygen carriers, with human umbilical cord hematopoietic stem/progenitor cells using an in vitro expansion system.

Biomimetic carbon monoxide delivery based on hemoglobin vesicles ameliorates acute pancreatitis in mice via the regulation of macrophage and neutrophil activity

Capillary blood flow during severe hemodilution observed by a noninvasive transcutaneous technique using flash epi-illumination.

Carbon monoxide-bound hemoglobin vesicles ameliorate multiorgan injuries induced by severe acute pancreatitis in mice by their anti-inflammatory and antioxidant properties

Carbon monoxide-bound hemoglobin-vesicles for the treatment of bleomycin-induced pulmonary fibrosis.

Cardiopulmonary hemodynamic responses to the small injection of hemoglobin vesicles (artificial oxygen carriers) in miniature pigs

Chapter 19 Hemoglobin-Vesicles as an Artificial Oxygen Carrier

Characteristics of Hb-vesicles and encapsulation procedure

Characteristics of bovine hemoglobin as a potential source of hemoglobin-vesicles for an artificial oxygen carrier.

Complete deoxygenation from a hemoglobin solution by an electrochemical method and heat treatment for virus inactivation.

Constriction of resistance arteries determines l-NAME-induced hypertension in a conscious hamster model.

Convenient method to purify hemoglobin

Detection of lipopolysaccharide in hemoglobin-vesicles by Limulus amebocyte lysate test with kinetic-turbidimetric gel clotting analysis and pretreatment of surfactant.

Effect of the cellular-type artificial oxygen carrier hemoglobin vesicle as a resuscitative fluid for prehospital treatment: experiments in a rat uncontrolled hemorrhagic shock model

Effects of hemoglobin vesicles, a liposomal artificial oxygen carrier, on hematological responses, complement and anaphylactic reactions in rats

Effects of poly(ethyleneglycol)-modified hemoglobin vesicles on agonist-induced platelet aggregation and RANTES release in vitro.

Efficacy of Resuscitative Transfusion With Hemoglobin Vesicles in the Treatment of Massive Hemorrhage in Rabbits With Thrombocytopenic Coagulopathy and Its Effect on Hemostasis by Platelet Transfusion

Encapsulation of concentrated hemoglobin solution in phospholipid vesicles retards the reaction with NO, but not CO, by intracellular diffusion barrier

Evaluation of a new type of nano-sized carbon monoxide donor on treating mice with experimentally induced colitis.

Fluid resuscitation of hemorrhagic shock with hemoglobin vesicles in Beagle dogs: pilot study.

Fluid resuscitation with hemoglobin vesicles prevents Escherichia coli growth via complement activation in a hemorrhagic shock rat model.

Fluid resuscitation with hemoglobin-vesicle solution does not increase hypoxia or inflammatory responses in moderate hemorrhagic shock

Gas bioengineering using hemoglobin-vesicles for versatile clinical applications.

Haemodynamics and oxygen tension in the microcirculation of ischaemic skin flaps after neural blockade and haemodilution.

Hemoglobin Vesicles prolong the time to circulatory collapse in rats during apnea

Hemoglobin encapsulation in vesicles retards NO and CO binding and O2 release when perfused through narrow gas-permeable tubes.

Hemoglobin vesicles containing methemoglobin and L-tyrosine to suppress methemoglobin formation in vitro and in vivo

Hemoglobin vesicles improve wound healing and tissue survival in critically ischemic skin in mice

Hemoglobin vesicles reduce hypoxia-related inflammation in critically ischemic hamster flap tissue

Hemoglobin vesicles, polyethylene glycol (PEG)ylated liposomes developed as a red blood cell substitute, do not induce the accelerated blood clearance phenomenon in mice

Hemoglobin-vesicles as a transfusion alternative.

Hemoglobin-vesicles suspended in recombinant human serum albumin for resuscitation from hemorrhagic shock in anesthetized rats.

Hemorrhagic shock resuscitation with an artificial oxygen carrier, hemoglobin vesicle, maintains intestinal perfusion and suppresses the increase in plasma tumor necrosis factor-alpha

Hepatically-metabolized and -excreted artificial oxygen carrier, hemoglobin vesicles, can be safely used under conditions of hepatic impairment.

Hidden Antioxidative Functions of Reduced Nicotinamide Adenine Dinucleotide Coexisting with Hemoglobin

Histopathological changes of rat brain after direct injection of Hb-vesicles (artificial oxygen carriers) and neurological impact in an intracerebral hemorrhage model.

Impact of human-derived hemoglobin based oxygen vesicles as a machine perfusion solution for liver donation after cardiac death in a pig model

In vivo evaluation of electron mediators for the reduction of methemoglobin encapsulated in liposomes using electron energies produced by red blood cell glycolysis.

Increased viscosity of hemoglobin-based oxygen carriers retards NO-binding when perfused through narrow gas-permeable tubes

Influence of erythrocyte aggregation at pathological levels on cell-free marginal layer in a narrow circular tube

Influence of hemoglobin vesicles, cellular-type artificial oxygen carriers, on human umbilical cord blood hematopoietic progenitor cells in vitro.

Inhibition effect of aggregation of phospholipid vesicles by incorporation of glycolipids

International Consortium for Development of Hemoglobin-Based Oxygen Carriers, Oxygen Therapeutics and Multifunctional Resuscitation Fluids–A White Paper

Intravenous injection of artificial red cells and subsequent dye laser irradiation causes deep vessel impairment in an animal model of port-wine stain

Is hemoglobin in hemoglobin vesicles infused for isovolemic hemodilution necessary to improve oxygenation in critically ischemic hamster skin?

Liposomal Artificial Red Blood Cell-Based Carbon Monoxide Donor Is a Potent Renoprotectant against Cisplatin-Induced Acute Kidney Injury

Liposomal microparticle injection can induce myeloid-derived suppressor cells (MDSC)-like cells in vivo.

Liposome-encapsulated hemoglobin (hemoglobin-vesicle) is not transferred from mother to fetus at the late stage of pregnancy in the rat model

Long-Term Stored Hemoglobin-Vesicles, a Cellular Type of Hemoglobin-Based Oxygen Carrier, Has Resuscitative Effects Comparable to That for Fresh Red Blood Cells in a Rat Model with Massive Hemorrhage without Post-Transfusion Lung Injury.

Mechanism of flocculate formation of highly concentrated phospholipid vesicles suspended in a series of water-soluble biopolymers.

Metabolism of hemoglobin-vesicles (artificial oxygen carriers) and their influence on organ functions in a rat model.

Methemoglobin formation in hemoglobin vesicles and reduction by encapsulated thiols

Microcirculation and NO-CO studies of a natural extracellular hemoglobin developed for an oxygen therapeutic carrier.

Model mice for Presbyterian hemoglobinopathy (Asn(beta108)-->Lys) confer hemolytic anemia with altered oxygen affinity and instability of Hb

NO and CO binding profiles of hemoglobin vesicles as artificial oxygen carriers

New generation of hemoglobin-based oxygen carriers evaluated for oxygenation of critically ischemic hamster flap tissue.

Normothermic preservation of the rat hind limb with artificial oxygen-carrying hemoglobin vesicles

One-year observation of Wistar rats after intravenous infusion of hemoglobin-vesicles (artificial oxygen carriers).

Oxygen affinity of hemoglobin regulates O2 consumption, metabolism, and physical activity

Oxygen transport by low and normal oxygen affinity hemoglobin vesicles in extreme hemodilution.

Peculiar flow patterns of RBCs suspended in viscous fluids and perfused through a narrow tube (25 microm).

Phagocytosis of liposome particles by rat splenic immature monocytes makes them transiently and highly immunosuppressive in ex vivo culture conditions

Pharmacokinetic study of enclosed hemoglobin and outer lipid component after the administration of hemoglobin vesicles as an artificial oxygen carrier.

Pharmacokinetics of single and repeated injection of hemoglobin-vesicles in hemorrhagic shock rat model

Phase separation of polymerized mixed liposomes: analysis of release behavior of entrapped molecules with skeletonization

Photoreduction of methemoglobin by irradiation in the near-ultraviolet region