Lista de obras - Michela Rugolo - Dominio Público Uruguay

'Behr syndrome' with OPA1 compound heterozygote mutations

artículo científico publicado en 2014

7-Ketocholesterol and staurosporine induce opposite changes in intracellular pH, associated with distinct types of cell death in ECV304 cells

artículo científico publicado en 2002

A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16.

artículo científico publicado en 2011

A mutation threshold distinguishes the antitumorigenic effects of the mitochondrial gene MTND1, an oncojanus function.

artículo científico publicado en 2011

A novel in-frame 18-bp microdeletion in MT-CYB causes a multisystem disorder with prominent exercise intolerance

artículo científico publicado en 2014

A volume-sensitive chloride conductance revealed in cultured human keratinocytes by 36Cl- efflux and whole-cell patch clamp recording

artículo científico publicado en 1992

Activation of Ca(2+)-dependent K+ and Cl- currents by UTP and ATP in CFPAC-1 cells

scientific article published on 01 April 1994

An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells

artículo científico publicado en 2009

Apoptotic cell death of cybrid cells bearing Leber's hereditary optic neuropathy mutations is caspase independent

artículo científico publicado en 2003

Arachidonic acid release by ionomycin and phorbol ester is similar in C127 epithelial cells expressing wild-type or mutated (delta F508) cystic fibrosis transmembrane conductance regulator

artículo científico publicado en 1999

Bioenergetics shapes cellular death pathways in Leber's hereditary optic neuropathy: a model of mitochondrial neurodegeneration

artículo científico publicado en 2004

Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G.

artículo científico publicado en 2005

Changes in membrane permeability in cells infected by human cytomegalovirus

artículo científico publicado en 1986

Characterization of chloride transport pathways in cultured human keratinocytes.

artículo científico publicado en 1991

Chloride transport in human fibroblasts is activated by hypotonic shock

artículo científico publicado en 1989

Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III.

artículo científico publicado en 2006

Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment

artículo científico publicado en 2013

Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors.

artículo científico publicado en 2007

Efflux of magnesium and potassium ions from liver mitochondria induced by inorganic phosphate and by diamide

artículo científico publicado en 1978

Extracellular 2-chloroadenosine and ATP stimulate volume-sensitive Cl- current and calcium mobilization in human tracheal 9HTEo- cells

artículo científico publicado en 1992

Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α.

artículo científico publicado en 2013

Glucose transport activation in human hematopoietic cells M07e is modulated by cytosolic calcium and calmodulin

artículo científico publicado en 2006

Green tea modulates alpha(1)-adrenergic stimulated glucose transport in cultured rat cardiomyocytes

artículo científico publicado en 2007

Hypotonic shock activated Cl- and K+ pathways in human fibroblasts

artículo científico publicado en 1991

Increased chloride efflux in fibroblasts from X-linked muscular dystrophies and clones from Duchenne carriers.

artículo científico publicado en 1987

Inhibition of the mitochondrial bc1 complex by dibromothymoquinone

artículo científico publicado en 1983

Involvement of endogenous phospholipase A2 in Ca2+ and Mg2+ movement induced by inorganic phosphate and diamide in rat liver mitochondria

artículo científico publicado en 1979

Kinetic alterations of cytochrome-c oxidase in cystic fibrosis

artículo científico publicado en 1986

Kinetic analysis of chloride efflux from normal and cystic fibrosis fibroblasts

artículo científico publicado en 1986

Learning from oncocytic tumors: Why choose inefficient mitochondria?

artículo científico publicado en 2010

Leber's hereditary optic neuropathy (LHON) pathogenic mutations induce mitochondrial-dependent apoptotic death in transmitochondrial cells incubated with galactose medium

artículo científico publicado en 2002

Mitochondria: Biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations.

artículo científico

Molecular mechanisms of superoxide production by complex III: A bacterial versus human mitochondrial comparative case study ⬇️

artículo científico publicado el 28 de marzo de 2013

Monitoring of the mitochondrial and plasma membrane potentials in human fibroblasts by tetraphenylphosphonium ion distribution

artículo científico publicado en 1987

OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion

artículo científico publicado en 2008

OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes

artículo científico publicado en 2008

Pertussis toxin- and PMA-insensitive calcium mobilization by sphingosine in CFPAC-1 cells: evidence for a phosphatidic acid-dependent mechanism

artículo científico publicado en 1997

Phosphate transport in mitochondria and submitochondrial particles: the influence of thiol oxidation

artículo científico publicado en 1977

Phospholipase D stimulation is required for sphingosine-1-phosphate activation of actin stress fibre assembly in human airway epithelial cells

artículo científico publicado en 2002

Phospholipase D1 is threonine-phosphorylated in human-airway epithelial cells stimulated by sphingosine-1-phosphate by a mechanism involving Src tyrosine kinase and protein kinase Cdelta

artículo científico publicado en 2002

Protection against oxidant-induced apoptosis by exogenous glutathione in Leber hereditary optic neuropathy cybrids

artículo científico publicado en 2008

Rare mtDNA variants in Leber hereditary optic neuropathy families with recurrence of myoclonus.

artículo científico publicado en 2008

Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels

artículo científico publicado en 2008

Role of CFTR and anion exchanger in bicarbonate fluxes in C127 cell lines.

artículo científico publicado en 1998

Sphingosine-1-phosphate activates phospholipase D in human airway epithelial cells via a G protein-coupled receptor

artículo científico publicado en 2000

Sphingosine-induced inhibition of capacitative calcium influx in CFPAC-1 cells

artículo científico publicado en 1996

Staurosporine induces apoptotic volume decrease (AVD) in ECV304 cells.

artículo científico publicado en 2003

Studies on the transport of carnitine in the brain using synaptosomes isolated from guinea-pig cerebral cortex.

artículo científico publicado en 1983

Syndromic parkinsonism and dementia associated with OPA1 missense mutations

artículo científico publicado en 2015

Synergic action of calcium ions and diamide on mitochondrial swelling

artículo científico publicado en 1975

The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I.

artículo científico publicado en 2008

The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity

artículo científico publicado en 2009

The cytochrome b p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes

artículo científico publicado en 2013

The effects of idebenone on mitochondrial bioenergetics ⬇️

artículo científico publicado en 2011

The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization

artículo científico publicado en 2009

The phorbol ester PMA and cyclic AMP activate different Cl(-) and HCO3(-) fluxes in C127 cells expressing CFTR.

artículo científico publicado en 2001

The response of chloride transport to cyclic AMP, calcium and hypotonic shock in normal and cystic fibrosis fibroblasts

artículo científico publicado en 1990

Volume regulation in human fibroblasts: role of Ca2+ and 5-lipoxygenase products in the activation of the Cl- efflux

scientific article published on 01 October 1993

Why mitochondria must fuse to maintain their genome integrity

artículo científico publicado en 2013

pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant

artículo científico publicado en 2005

Lista de obras de Michela Rugolo

'Behr syndrome' with OPA1 compound heterozygote mutations

7-Ketocholesterol and staurosporine induce opposite changes in intracellular pH, associated with distinct types of cell death in ECV304 cells

A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16.

A mutation threshold distinguishes the antitumorigenic effects of the mitochondrial gene MTND1, an oncojanus function.

A novel in-frame 18-bp microdeletion in MT-CYB causes a multisystem disorder with prominent exercise intolerance

A volume-sensitive chloride conductance revealed in cultured human keratinocytes by 36Cl- efflux and whole-cell patch clamp recording

Activation of Ca(2+)-dependent K+ and Cl- currents by UTP and ATP in CFPAC-1 cells

An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells

Apoptotic cell death of cybrid cells bearing Leber's hereditary optic neuropathy mutations is caspase independent

Arachidonic acid release by ionomycin and phorbol ester is similar in C127 epithelial cells expressing wild-type or mutated (delta F508) cystic fibrosis transmembrane conductance regulator

Bioenergetics shapes cellular death pathways in Leber's hereditary optic neuropathy: a model of mitochondrial neurodegeneration

Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G.

Changes in membrane permeability in cells infected by human cytomegalovirus

Characterization of chloride transport pathways in cultured human keratinocytes.

Chloride transport in human fibroblasts is activated by hypotonic shock

Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III.

Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment

Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors.

Efflux of magnesium and potassium ions from liver mitochondria induced by inorganic phosphate and by diamide

Extracellular 2-chloroadenosine and ATP stimulate volume-sensitive Cl- current and calcium mobilization in human tracheal 9HTEo- cells

Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α.

Glucose transport activation in human hematopoietic cells M07e is modulated by cytosolic calcium and calmodulin

Green tea modulates alpha(1)-adrenergic stimulated glucose transport in cultured rat cardiomyocytes

Hypotonic shock activated Cl- and K+ pathways in human fibroblasts

Increased chloride efflux in fibroblasts from X-linked muscular dystrophies and clones from Duchenne carriers.

Inhibition of the mitochondrial bc1 complex by dibromothymoquinone

Involvement of endogenous phospholipase A2 in Ca2+ and Mg2+ movement induced by inorganic phosphate and diamide in rat liver mitochondria

Kinetic alterations of cytochrome-c oxidase in cystic fibrosis

Kinetic analysis of chloride efflux from normal and cystic fibrosis fibroblasts

Learning from oncocytic tumors: Why choose inefficient mitochondria?

Leber's hereditary optic neuropathy (LHON) pathogenic mutations induce mitochondrial-dependent apoptotic death in transmitochondrial cells incubated with galactose medium

Mitochondria: Biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations.

Molecular mechanisms of superoxide production by complex III: A bacterial versus human mitochondrial comparative case study ⬇️

Monitoring of the mitochondrial and plasma membrane potentials in human fibroblasts by tetraphenylphosphonium ion distribution

OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion

OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes

Pertussis toxin- and PMA-insensitive calcium mobilization by sphingosine in CFPAC-1 cells: evidence for a phosphatidic acid-dependent mechanism

Phosphate transport in mitochondria and submitochondrial particles: the influence of thiol oxidation

Phospholipase D stimulation is required for sphingosine-1-phosphate activation of actin stress fibre assembly in human airway epithelial cells

Phospholipase D1 is threonine-phosphorylated in human-airway epithelial cells stimulated by sphingosine-1-phosphate by a mechanism involving Src tyrosine kinase and protein kinase Cdelta

Protection against oxidant-induced apoptosis by exogenous glutathione in Leber hereditary optic neuropathy cybrids

Rare mtDNA variants in Leber hereditary optic neuropathy families with recurrence of myoclonus.

Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels

Role of CFTR and anion exchanger in bicarbonate fluxes in C127 cell lines.

Sphingosine-1-phosphate activates phospholipase D in human airway epithelial cells via a G protein-coupled receptor

Sphingosine-induced inhibition of capacitative calcium influx in CFPAC-1 cells

Staurosporine induces apoptotic volume decrease (AVD) in ECV304 cells.

Studies on the transport of carnitine in the brain using synaptosomes isolated from guinea-pig cerebral cortex.

Syndromic parkinsonism and dementia associated with OPA1 missense mutations

Synergic action of calcium ions and diamide on mitochondrial swelling

The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I.

The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity

The cytochrome b p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes

The effects of idebenone on mitochondrial bioenergetics ⬇️

The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization

The phorbol ester PMA and cyclic AMP activate different Cl(-) and HCO3(-) fluxes in C127 cells expressing CFTR.

The response of chloride transport to cyclic AMP, calcium and hypotonic shock in normal and cystic fibrosis fibroblasts

Volume regulation in human fibroblasts: role of Ca2+ and 5-lipoxygenase products in the activation of the Cl- efflux

Why mitochondria must fuse to maintain their genome integrity

pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant