Lista de obras - Jennifer L McKimm-Breschkin

A clinical trial lacking a control group

scientific article published on 16 October 2019

A generic system for the expression and purification of soluble and stable influenza neuraminidase

artículo científico publicado en 2011

A new method for the purification of the influenza A virus neuraminidase.

artículo científico publicado en 1991

A simplified plaque assay for respiratory syncytial virus--direct visualization of plaques without immunostaining

artículo científico publicado en 2004

Affinity ranking of influenza neuraminidase mutants with monoclonal antibodies using an optical biosensor. Comparison with ELISA and slot blot assays

artículo científico publicado en 1994

Anti-oxazolone hybridomas and strain distribution of the oxazolone idiotype

scientific article published on 01 November 1983

Catalytic mechanism and novel receptor binding sites of human parainfluenza virus type 3 hemagglutinin-neuraminidase (hPIV3 HN)

artículo científico publicado en 2015

Changes in the NS gene of neurovirulent strains of influenza affect splicing.

artículo científico publicado en 1995

Characterisation of an avian influenza virus nucleoprotein expressed in E. coli and in insect cells.

artículo científico publicado en 1990

Complexity in influenza virus targeted drug design: interaction with human sialidases.

artículo científico publicado en 2010

Detection of influenza viruses resistant to neuraminidase inhibitors in global surveillance during the first 3 years of their use.

artículo científico publicado en 2006

Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza.

artículo científico publicado en 2005

Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase ⬇️

artículo científico publicado el 15 de junio de 1998

ER stress triggers apoptosis by activating BH3-only protein Bim

artículo científico publicado en 2007

Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: report of the neuraminidase inhibitor susceptibility network.

artículo científico publicado en 2003

Expression of influenza neuraminidase in baculovirus-infected cells

artículo científico publicado en 1992

I222 Neuraminidase mutations further reduce oseltamivir susceptibility of Indonesian Clade 2.1 highly pathogenic Avian Influenza A(H5N1) viruses

artículo científico publicado en 2013

Identification of Indonesian clade 2.1 highly pathogenic influenza A(H5N1) viruses with N294S and S246N neuraminidase substitutions which further reduce oseltamivir susceptibility.

artículo científico publicado en 2018

Identification of a human influenza type B strain with reduced sensitivity to neuraminidase inhibitor drugs

artículo científico publicado en 2004

In vitro passaging of a pandemic H1N1/09 virus selects for viruses with neuraminidase mutations conferring high-level resistance to oseltamivir and peramivir, but not to zanamivir

artículo científico publicado en 2012

Influenza Virus Neuraminidase Structure and Functions

artículo científico publicado en 2019

Influenza neuraminidase inhibitors: antiviral action and mechanisms of resistance ⬇️

artículo científico publicado el 1 de enero de 2013

Inhibition of parainfluenza virus type 3 and Newcastle disease virus hemagglutinin-neuraminidase receptor binding: effect of receptor avidity and steric hindrance at the inhibitor binding sites.

artículo científico publicado en 2004

Interferon induction by measles virus.

artículo científico publicado en 1981

Isolation of very virulent Marek's disease viruses from vaccinated chickens in Australia

artículo científico publicado en 1990

Liquid nitrogen storage of cultured T lymphocytes

artículo científico publicado en 1985

Management of influenza virus infections with neuraminidase inhibitors: detection, incidence, and implications of drug resistance

artículo científico publicado en 2005

Mechanism-based covalent neuraminidase inhibitors with broad-spectrum influenza antiviral activity

artículo científico publicado en 2013

Meeting report: 4th ISIRV antiviral group conference: Novel antiviral therapies for influenza and other respiratory viruses

artículo científico publicado en 2016

Mixed influenza A and B infections complicate the detection of influenza viruses with altered sensitivities to neuraminidase inhibitors

artículo científico publicado en 2011

Mouse Saliva Inhibits Transit of Influenza Virus to the Lower Respiratory Tract by Efficiently Blocking Influenza Virus Neuraminidase Activity.

artículo científico publicado en 2017

Mutations conferring zanamivir resistance in human influenza virus N2 neuraminidases compromise virus fitness and are not stably maintained in vitro.

artículo científico publicado en 2006

Neuraminidase inhibitor susceptibility network position statement: antiviral resistance in influenza A/H5N1 viruses.

artículo científico publicado en 2005

Neuraminidase inhibitor-resistant and -sensitive influenza B viruses isolated from an untreated human patient

artículo científico publicado en 2006

Neuraminidase inhibitors for the treatment and prevention of influenza

artículo científico publicado en 2002

Neuraminidase mutations conferring resistance to laninamivir lead to faster drug binding and dissociation

artículo científico publicado en 2014

Neuraminidase sequence analysis and susceptibilities of influenza virus clinical isolates to zanamivir and oseltamivir.

artículo científico publicado en 2003

News about influenza B drug resistance that cannot be ignored

artículo científico publicado en 2007

Passaging of an influenza A(H1N1)pdm09 virus in a difluoro sialic acid inhibitor selects for a novel, but unfit I106M neuraminidase mutant

artículo científico publicado en 2019

Pertussigen enhances antigen-driven interferon-gamma production by sensitized lymphoid cells

scientific article published on 01 February 1986

Plaque formation assay for human parainfluenza virus type 1.

artículo científico publicado en 2011

Preparation of T cell growth factor free from interferon and factors stimulating hemopoietic cells and mast cells

artículo científico publicado en 1982

Prevention and treatment of respiratory viral infections: Presentations on antivirals, traditional therapies and host-directed interventions at the 5th ISIRV Antiviral Group conference

artículo científico publicado en 2017

Real time enzyme inhibition assays provide insights into differences in binding of neuraminidase inhibitors to wild type and mutant influenza viruses

artículo científico publicado en 2011

Reduced sensitivity of influenza A (H5N1) to oseltamivir

artículo científico publicado en 2007

Reduced susceptibility to all neuraminidase inhibitors of influenza H1N1 viruses with haemagglutinin mutations and mutations in non-conserved residues of the neuraminidase.

artículo científico publicado en 2013

Resistance of influenza viruses to neuraminidase inhibitors--a review.

artículo científico publicado en 2000

Solid phase assay for comparing reactivation rates of neuraminidases of influenza wild type and resistant mutants after inhibitor removal.

artículo científico publicado en 2014

Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses

artículo científico publicado en 2010

Structural and functional analysis of anti-influenza activity of 4-, 7-, 8- and 9-deoxygenated 2,3-difluoro-N-acetylneuraminic acid derivatives.

artículo científico publicado en 2018

Structural evidence for a second sialic acid binding site in avian influenza virus neuraminidases ⬇️

artículo científico publicado el 28 de octubre de 1997

Structure of a calcium-deficient form of influenza virus neuraminidase: implications for substrate binding

artículo científico publicado en 2006

Structure of an Influenza A virus N9 neuraminidase with a tetrabrachion-domain stalk

scientific article published on 23 January 2019

Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III

artículo científico publicado en 2004

Substitutions at H134 and in the 430-loop region in influenza B neuraminidases can confer reduced susceptibility to multiple neuraminidase inhibitors

artículo científico publicado en 2020

Substrate, inhibitor, or antibody stabilizes the Glu 119 Gly mutant influenza virus neuraminidase.

artículo científico publicado en 1998

Surveillance for neuraminidase-inhibitor-resistant influenza viruses in Japan, 1996-2007.

artículo científico publicado en 2009

Taking down the FLAG! How insect cell expression challenges an established tag-system

artículo científico publicado en 2012

Tethered neuraminidase inhibitors that bind an influenza virus: a first step towards a diagnostic method for influenza.

artículo científico publicado en 2003

The Interaction of Neuraminidase and Hemagglutinin Mutations in Influenza Virus in Resistance to 4-Guanidino-Neu5Ac2en ⬇️

artículo científico publicado el 20 de junio de 1998

The neuraminidases of MDCK grown human influenza A(H3N2) viruses isolated since 1994 can demonstrate receptor binding.

artículo científico publicado en 2015

The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor

artículo científico publicado el 1 de noviembre de 1992

The structure of the fusion glycoprotein of Newcastle disease virus suggests a novel paradigm for the molecular mechanism of membrane fusion

artículo científico publicado en 2001

The use of tetramethylbenzidine for solid phase immunoassays

scientific article published on 01 December 1990

Use of oligonucleotide probes for selecting potential high-yielding influenza reassortants

scientific article published on 01 November 1997

Lista de obras de Jennifer L McKimm-Breschkin

A clinical trial lacking a control group

A generic system for the expression and purification of soluble and stable influenza neuraminidase

A new method for the purification of the influenza A virus neuraminidase.

A simplified plaque assay for respiratory syncytial virus--direct visualization of plaques without immunostaining

Affinity ranking of influenza neuraminidase mutants with monoclonal antibodies using an optical biosensor. Comparison with ELISA and slot blot assays

Anti-oxazolone hybridomas and strain distribution of the oxazolone idiotype

Catalytic mechanism and novel receptor binding sites of human parainfluenza virus type 3 hemagglutinin-neuraminidase (hPIV3 HN)

Changes in the NS gene of neurovirulent strains of influenza affect splicing.

Characterisation of an avian influenza virus nucleoprotein expressed in E. coli and in insect cells.

Complexity in influenza virus targeted drug design: interaction with human sialidases.

Detection of influenza viruses resistant to neuraminidase inhibitors in global surveillance during the first 3 years of their use.

Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza.

Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase ⬇️

ER stress triggers apoptosis by activating BH3-only protein Bim

Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: report of the neuraminidase inhibitor susceptibility network.

Expression of influenza neuraminidase in baculovirus-infected cells

I222 Neuraminidase mutations further reduce oseltamivir susceptibility of Indonesian Clade 2.1 highly pathogenic Avian Influenza A(H5N1) viruses

Identification of Indonesian clade 2.1 highly pathogenic influenza A(H5N1) viruses with N294S and S246N neuraminidase substitutions which further reduce oseltamivir susceptibility.

Identification of a human influenza type B strain with reduced sensitivity to neuraminidase inhibitor drugs

In vitro passaging of a pandemic H1N1/09 virus selects for viruses with neuraminidase mutations conferring high-level resistance to oseltamivir and peramivir, but not to zanamivir

Influenza Virus Neuraminidase Structure and Functions

Influenza neuraminidase inhibitors: antiviral action and mechanisms of resistance ⬇️

Inhibition of parainfluenza virus type 3 and Newcastle disease virus hemagglutinin-neuraminidase receptor binding: effect of receptor avidity and steric hindrance at the inhibitor binding sites.

Interferon induction by measles virus.

Isolation of very virulent Marek's disease viruses from vaccinated chickens in Australia

Liquid nitrogen storage of cultured T lymphocytes

Management of influenza virus infections with neuraminidase inhibitors: detection, incidence, and implications of drug resistance

Mechanism-based covalent neuraminidase inhibitors with broad-spectrum influenza antiviral activity

Meeting report: 4th ISIRV antiviral group conference: Novel antiviral therapies for influenza and other respiratory viruses

Mixed influenza A and B infections complicate the detection of influenza viruses with altered sensitivities to neuraminidase inhibitors

Mouse Saliva Inhibits Transit of Influenza Virus to the Lower Respiratory Tract by Efficiently Blocking Influenza Virus Neuraminidase Activity.

Mutations conferring zanamivir resistance in human influenza virus N2 neuraminidases compromise virus fitness and are not stably maintained in vitro.

Neuraminidase inhibitor susceptibility network position statement: antiviral resistance in influenza A/H5N1 viruses.

Neuraminidase inhibitor-resistant and -sensitive influenza B viruses isolated from an untreated human patient

Neuraminidase inhibitors for the treatment and prevention of influenza

Neuraminidase mutations conferring resistance to laninamivir lead to faster drug binding and dissociation

Neuraminidase sequence analysis and susceptibilities of influenza virus clinical isolates to zanamivir and oseltamivir.

News about influenza B drug resistance that cannot be ignored

Passaging of an influenza A(H1N1)pdm09 virus in a difluoro sialic acid inhibitor selects for a novel, but unfit I106M neuraminidase mutant

Pertussigen enhances antigen-driven interferon-gamma production by sensitized lymphoid cells

Plaque formation assay for human parainfluenza virus type 1.

Preparation of T cell growth factor free from interferon and factors stimulating hemopoietic cells and mast cells

Prevention and treatment of respiratory viral infections: Presentations on antivirals, traditional therapies and host-directed interventions at the 5th ISIRV Antiviral Group conference

Real time enzyme inhibition assays provide insights into differences in binding of neuraminidase inhibitors to wild type and mutant influenza viruses

Reduced sensitivity of influenza A (H5N1) to oseltamivir

Reduced susceptibility to all neuraminidase inhibitors of influenza H1N1 viruses with haemagglutinin mutations and mutations in non-conserved residues of the neuraminidase.

Resistance of influenza viruses to neuraminidase inhibitors--a review.

Solid phase assay for comparing reactivation rates of neuraminidases of influenza wild type and resistant mutants after inhibitor removal.

Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses

Structural and functional analysis of anti-influenza activity of 4-, 7-, 8- and 9-deoxygenated 2,3-difluoro-N-acetylneuraminic acid derivatives.

Structural evidence for a second sialic acid binding site in avian influenza virus neuraminidases ⬇️

Structure of a calcium-deficient form of influenza virus neuraminidase: implications for substrate binding

Structure of an Influenza A virus N9 neuraminidase with a tetrabrachion-domain stalk

Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III

Substitutions at H134 and in the 430-loop region in influenza B neuraminidases can confer reduced susceptibility to multiple neuraminidase inhibitors

Substrate, inhibitor, or antibody stabilizes the Glu 119 Gly mutant influenza virus neuraminidase.

Surveillance for neuraminidase-inhibitor-resistant influenza viruses in Japan, 1996-2007.

Taking down the FLAG! How insect cell expression challenges an established tag-system

Tethered neuraminidase inhibitors that bind an influenza virus: a first step towards a diagnostic method for influenza.

The Interaction of Neuraminidase and Hemagglutinin Mutations in Influenza Virus in Resistance to 4-Guanidino-Neu5Ac2en ⬇️

The neuraminidases of MDCK grown human influenza A(H3N2) viruses isolated since 1994 can demonstrate receptor binding.

The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor

The structure of the fusion glycoprotein of Newcastle disease virus suggests a novel paradigm for the molecular mechanism of membrane fusion

The use of tetramethylbenzidine for solid phase immunoassays

Use of oligonucleotide probes for selecting potential high-yielding influenza reassortants

Zanamivir