Lista de obras - Christian M Hedrich - Dominio Público Uruguay

"Mutation negative" familial cold autoinflammatory syndrome (FCAS) in an 8-year-old boy: clinical course and functional studies

artículo científico publicado en 2011

A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome.

scientific article published on 09 September 2009

A novel isoform of the orphan receptor RORγt suppresses IL-17 production in human T cells

artículo científico publicado en 2012

Acrodermatitis Chronica Atrophicans.

artículo científico publicado en 2015

Altered expression of IL-10 family cytokines in CRMO result in enhanced inflammasome activation.

artículo científico publicado en 2015

Altered expression of IL-10 family cytokines in monocytes from CRMO patients result in enhanced IL-1β expression and release

artículo científico publicado en 2015

Anakinra: a safe and effective first-line treatment in systemic onset juvenile idiopathic arthritis (SoJIA)

artículo científico publicado en 2011

Attenuated TLR4/MAPK signaling in monocytes from patients with CRMO results in impaired IL-10 expression.

artículo científico publicado en 2012

Autoinflammatory bone disorders with special focus on chronic recurrent multifocal osteomyelitis (CRMO).

artículo científico publicado en 2013

Autoinflammatory bone disorders.

artículo científico

Autologous stem cell transplantation in refractory paediatric Wegener's granulomatosis

artículo científico publicado el 1 de septiembre de 2011

Autosomal dominant neurohypophyseal diabetes insipidus in two families. Molecular analysis of the vasopressin-neurophysin II gene and functional studies of three missense mutations.

artículo científico publicado en 2009

Biological properties and regulation of IL-10 related cytokines and their contribution to autoimmune disease and tissue injury.

artículo científico publicado en 2012

Bridging the gap between autoinflammation and autoimmunity

artículo científico publicado en 2013

CD3-T Cell Receptor Co-stimulation through SLAMF3 and SLAMF6 Receptors Enhances RORγt Recruitment to the IL17A Promoter in Human T Lymphocytes ⬇️

artículo científico publicado el 18 de septiembre de 2012

CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance

artículo científico publicado en 2014

Caspase-1 regulates autoinflammation in rheumatic diseases

artículo científico publicado en 2016

Cell-Specific Requirements for STAT Proteins and Type I IFN Receptor Signaling Discretely Regulate IL-24 and IL-10 Expression in NK Cells and Macrophages.

artículo científico publicado en 2018

Chilblain lupus erythematosus--a review of literature.

artículo científico publicado en 2008

Chilblain lupus erythematosus-a review of literature.

artículo científico publicado en 2008

Choosing the right treatment for patients with a severe course of chronic non-bacterial osteomyelitis (CNO) - pamidronate or TNF-α blockade?

artículo científico publicado en 2015

Chorioretinitis in a 7-year-old African girl, probably related to JSSc resolving to methotrexate therapy ⬇️

artículo científico publicado el 3 de febrero de 2011

Chronic non-bacterial osteomyelitis is associated with impaired Sp1 signaling, reduced IL10 promoter phosphorylation, and reduced myeloid IL-10 expression.

artículo científico publicado en 2011

Clinical and laboratory characteristics in juvenile-onset systemic lupus erythematosus across age groups

artículo científico publicado en 2020

Clinical and laboratory phenotypes in juvenile-onset Systemic Lupus Erythematosus across ethnicities in the UK

artículo científico publicado en 2021

Current understanding of the pathophysiology of systemic juvenile idiopathic arthritis (sJIA) and target-directed therapeutic approaches

artículo científico

DNA methylation in systemic lupus erythematosus

artículo científico publicado en 2016

Diclofenac inhibits proliferation and matrix formation of osteoblast cells

artículo científico publicado en 2005

Dynamic CpG-DNA methylation of Il10 and Il19 in CD4+ T lymphocytes and macrophages: effects on tissue-specific gene expression

artículo científico publicado en 2011

Dynamic DNA methylation patterns across the mouse and human IL10 genes during CD4+ T cell activation; influence of IL-27.

artículo científico publicado en 2010

Early onset systemic lupus erythematosus: differential diagnoses, clinical presentation, and treatment options.

scientific article published on October 2010

Enzymatically Inactive Procaspase 1 stabilizes the ASC Pyroptosome and Supports Pyroptosome Spreading during Cell Division

artículo científico publicado en 2016

Epigenetic mechanisms in systemic lupus erythematosus and other autoimmune diseases

artículo científico publicado en 2011

Epigenetic patterns in systemic sclerosis and their contribution to attenuated CD70 signaling cascades

artículo científico publicado en 2012

Epigenetic regulation of cytokine expression in systemic lupus erythematosus with special focus on T cells

artículo científico publicado en 2014

Fluorescent tags influence the enzymatic activity and subcellular localization of procaspase-1.

artículo científico publicado en 2015

Gene-function studies in systemic lupus erythematosus.

artículo científico

Good response to IL-1beta blockade by anakinra in a 23-year-old CINCA/NOMID patient without mutations in the CIAS1 gene. Cytokine profiles and functional studies

artículo científico publicado en 2008

Innately Adaptive or Truly Autoimmune: Is There Something Unique About Systemic Juvenile Idiopathic Arthritis?

scientific article published on 02 January 2020

Mast cells enhance sterile inflammation in chronic nonbacterial osteomyelitis

scientific article published on 20 August 2019

Meningoencephalitis caused by varicella-zoster virus reactivation in a child with dominant partial interferon-gamma receptor-1 deficiency ⬇️

artículo científico publicado el 1 de marzo de 2011

Orbital inflammation and colitis in pediatric IgG4-related disease: A case report and review of the literature

artículo científico publicado en 2019

Panel sequencing links rare, likely damaging gene variants with distinct clinical phenotypes and outcomes in juvenile-onset SLE

artículo científico publicado en 2022

Pilot study: possible association of IL10 promoter polymorphisms with CRMO

artículo científico publicado en 2011

Presentations and treatment of childhood scleroderma: localized scleroderma, eosinophilic fasciitis, systemic sclerosis, and graft-versus-host disease

artículo científico publicado en 2011

Protein Phosphatase 2A Enables Expression of Interleukin 17 (IL-17) through Chromatin Remodeling ⬇️

artículo científico publicado el 5 de agosto de 2013

SNPs talk to genes using landlines: long-range chromatin interactions link genetic risk with epigenetic patterns in Takayasu arteritis

artículo científico publicado en 2019

Serum biomarkers for the diagnosis and monitoring of chronic recurrent multifocal osteomyelitis (CRMO).

artículo científico publicado en 2016

Serum biomarkers for the diagnosis of chronic recurrent multifocal osteomyelitis (CRMO).

artículo científico publicado en 2015

Shaping the spectrum - From autoinflammation to autoimmunity.

artículo científico publicado en 2016

Stat3 promotes IL-10 expression in lupus T cells through trans-activation and chromatin remodeling

artículo científico publicado en 2014

Still's disease in children and adults

artículo científico publicado en 2017

TCR+CD3+CD4-CD8- effector T cells in psoriasis

artículo científico

Treatment Response and Longterm Outcomes in Children with Chronic Nonbacterial Osteomyelitis.

artículo científico publicado en 2017

Unexpectedly high incidences of chronic non-bacterial as compared to bacterial osteomyelitis in children.

artículo científico publicado en 2016

Update: Cytokine Dysregulation in Chronic Nonbacterial Osteomyelitis (CNO) ⬇️

artículo científico publicado el 21 de mayo de 2012

Urine and serum S100A8/A9 and S100A12 associate with active lupus nephritis and may predict response to rituximab treatment

artículo científico publicado en 2020

[Inflammasome and gout]

artículo científico publicado en 2016

[Osteoid osteomas of the fingers: an atypical localization? Two case reports and a review of the literature]

artículo científico publicado en 2008

cAMP Response Element Modulator α Induces Dual Specificity Protein Phosphatase 4 to Promote Effector T Cells in Juvenile-Onset Lupus

scientific article published on 25 October 2019

cAMP response element modulator α controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus.

artículo científico publicado en 2012

cAMP responsive element modulator (CREM) α mediates chromatin remodeling of CD8 during the generation of CD3+ CD4- CD8- T cells

artículo científico publicado en 2013

cAMP responsive element modulator: a critical regulator of cytokine production

artículo científico publicado en 2013

cAMP-responsive element modulator (CREM)α protein induces interleukin 17A expression and mediates epigenetic alterations at the interleukin-17A gene locus in patients with systemic lupus erythematosus

artículo científico publicado en 2011

cAMP-responsive element modulator (CREM)α protein signaling mediates epigenetic remodeling of the human interleukin-2 gene: implications in systemic lupus erythematosus

artículo científico publicado en 2011

cAMP-responsive element modulator α (CREMα) suppresses IL-17F protein expression in T lymphocytes from patients with systemic lupus erythematosus (SLE).

artículo científico publicado en 2011

cAMP-responsive element modulator α (CREMα) trans-represses the transmembrane glycoprotein CD8 and contributes to the generation of CD3+CD4-CD8- T cells in health and disease

artículo científico publicado en 2013

Lista de obras de Christian M Hedrich

"Mutation negative" familial cold autoinflammatory syndrome (FCAS) in an 8-year-old boy: clinical course and functional studies

A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome.

A novel isoform of the orphan receptor RORγt suppresses IL-17 production in human T cells

Acrodermatitis Chronica Atrophicans.

Altered expression of IL-10 family cytokines in CRMO result in enhanced inflammasome activation.

Altered expression of IL-10 family cytokines in monocytes from CRMO patients result in enhanced IL-1β expression and release

Anakinra: a safe and effective first-line treatment in systemic onset juvenile idiopathic arthritis (SoJIA)

Attenuated TLR4/MAPK signaling in monocytes from patients with CRMO results in impaired IL-10 expression.

Autoinflammatory bone disorders with special focus on chronic recurrent multifocal osteomyelitis (CRMO).

Autoinflammatory bone disorders.

Autologous stem cell transplantation in refractory paediatric Wegener's granulomatosis

Autosomal dominant neurohypophyseal diabetes insipidus in two families. Molecular analysis of the vasopressin-neurophysin II gene and functional studies of three missense mutations.

Biological properties and regulation of IL-10 related cytokines and their contribution to autoimmune disease and tissue injury.

Bridging the gap between autoinflammation and autoimmunity

CD3-T Cell Receptor Co-stimulation through SLAMF3 and SLAMF6 Receptors Enhances RORγt Recruitment to the IL17A Promoter in Human T Lymphocytes ⬇️

CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance

Caspase-1 regulates autoinflammation in rheumatic diseases

Cell-Specific Requirements for STAT Proteins and Type I IFN Receptor Signaling Discretely Regulate IL-24 and IL-10 Expression in NK Cells and Macrophages.

Chilblain lupus erythematosus--a review of literature.

Chilblain lupus erythematosus-a review of literature.

Choosing the right treatment for patients with a severe course of chronic non-bacterial osteomyelitis (CNO) - pamidronate or TNF-α blockade?

Chorioretinitis in a 7-year-old African girl, probably related to JSSc resolving to methotrexate therapy ⬇️

Chronic non-bacterial osteomyelitis is associated with impaired Sp1 signaling, reduced IL10 promoter phosphorylation, and reduced myeloid IL-10 expression.

Clinical and laboratory characteristics in juvenile-onset systemic lupus erythematosus across age groups

Clinical and laboratory phenotypes in juvenile-onset Systemic Lupus Erythematosus across ethnicities in the UK

Current understanding of the pathophysiology of systemic juvenile idiopathic arthritis (sJIA) and target-directed therapeutic approaches

DNA methylation in systemic lupus erythematosus

Diclofenac inhibits proliferation and matrix formation of osteoblast cells

Dynamic CpG-DNA methylation of Il10 and Il19 in CD4+ T lymphocytes and macrophages: effects on tissue-specific gene expression

Dynamic DNA methylation patterns across the mouse and human IL10 genes during CD4+ T cell activation; influence of IL-27.

Early onset systemic lupus erythematosus: differential diagnoses, clinical presentation, and treatment options.

Enzymatically Inactive Procaspase 1 stabilizes the ASC Pyroptosome and Supports Pyroptosome Spreading during Cell Division

Epigenetic mechanisms in systemic lupus erythematosus and other autoimmune diseases

Epigenetic patterns in systemic sclerosis and their contribution to attenuated CD70 signaling cascades

Epigenetic regulation of cytokine expression in systemic lupus erythematosus with special focus on T cells

Fluorescent tags influence the enzymatic activity and subcellular localization of procaspase-1.

Gene-function studies in systemic lupus erythematosus.

Good response to IL-1beta blockade by anakinra in a 23-year-old CINCA/NOMID patient without mutations in the CIAS1 gene. Cytokine profiles and functional studies

Innately Adaptive or Truly Autoimmune: Is There Something Unique About Systemic Juvenile Idiopathic Arthritis?

Mast cells enhance sterile inflammation in chronic nonbacterial osteomyelitis

Meningoencephalitis caused by varicella-zoster virus reactivation in a child with dominant partial interferon-gamma receptor-1 deficiency ⬇️

Orbital inflammation and colitis in pediatric IgG4-related disease: A case report and review of the literature

Panel sequencing links rare, likely damaging gene variants with distinct clinical phenotypes and outcomes in juvenile-onset SLE

Pilot study: possible association of IL10 promoter polymorphisms with CRMO

Presentations and treatment of childhood scleroderma: localized scleroderma, eosinophilic fasciitis, systemic sclerosis, and graft-versus-host disease

Protein Phosphatase 2A Enables Expression of Interleukin 17 (IL-17) through Chromatin Remodeling ⬇️

SNPs talk to genes using landlines: long-range chromatin interactions link genetic risk with epigenetic patterns in Takayasu arteritis

Serum biomarkers for the diagnosis and monitoring of chronic recurrent multifocal osteomyelitis (CRMO).

Serum biomarkers for the diagnosis of chronic recurrent multifocal osteomyelitis (CRMO).

Shaping the spectrum - From autoinflammation to autoimmunity.

Stat3 promotes IL-10 expression in lupus T cells through trans-activation and chromatin remodeling

Still's disease in children and adults

TCR+CD3+CD4-CD8- effector T cells in psoriasis

Treatment Response and Longterm Outcomes in Children with Chronic Nonbacterial Osteomyelitis.

Unexpectedly high incidences of chronic non-bacterial as compared to bacterial osteomyelitis in children.

Update: Cytokine Dysregulation in Chronic Nonbacterial Osteomyelitis (CNO) ⬇️

Urine and serum S100A8/A9 and S100A12 associate with active lupus nephritis and may predict response to rituximab treatment

[Inflammasome and gout]

[Osteoid osteomas of the fingers: an atypical localization? Two case reports and a review of the literature]

cAMP Response Element Modulator α Induces Dual Specificity Protein Phosphatase 4 to Promote Effector T Cells in Juvenile-Onset Lupus

cAMP response element modulator α controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus.

cAMP responsive element modulator (CREM) α mediates chromatin remodeling of CD8 during the generation of CD3+ CD4- CD8- T cells

cAMP responsive element modulator: a critical regulator of cytokine production

cAMP-responsive element modulator (CREM)α protein induces interleukin 17A expression and mediates epigenetic alterations at the interleukin-17A gene locus in patients with systemic lupus erythematosus

cAMP-responsive element modulator (CREM)α protein signaling mediates epigenetic remodeling of the human interleukin-2 gene: implications in systemic lupus erythematosus

cAMP-responsive element modulator α (CREMα) suppresses IL-17F protein expression in T lymphocytes from patients with systemic lupus erythematosus (SLE).

cAMP-responsive element modulator α (CREMα) trans-represses the transmembrane glycoprotein CD8 and contributes to the generation of CD3+CD4-CD8- T cells in health and disease