Lista de obras - Juan Chen - Dominio Público Uruguay

"Zipper" molecular beacons: a generalized strategy to optimize the performance of activatable protease probes

artículo científico publicado en 2009

A Nanoemulsion with A Porphyrin Shell for Cancer Theranostics

scientific article published on 05 September 2019

A PEGylation-Free Biomimetic Porphyrin Nanoplatform for Personalized Cancer Theranostics

artículo científico publicado en 2015

A tumor mRNA-triggered photodynamic molecular beacon based on oligonucleotide hairpin control of singlet oxygen production

artículo científico publicado en 2008

Ablation of hypoxic tumors with dose-equivalent photothermal, but not photodynamic, therapy using a nanostructured porphyrin assembly

artículo científico publicado en 2013

Activatable photosensitizers for imaging and therapy.

artículo científico publicado en 2010

Activation Kinetics of Zipper Molecular Beacons

Attenuation of nontargeted cell-kill using a high-density lipoprotein-mimicking peptide--phospholipid nanoscaffold.

artículo científico publicado en 2011

Biologically-targeted detection of primary and micro-metastatic ovarian cancer

artículo científico publicado en 2013

Biomimetic nanocarrier for direct cytosolic drug delivery.

artículo científico publicado en 2009

Chlorosome-Inspired Synthesis of Templated Metallochlorin-Lipid Nanoassemblies for Biomedical Applications

artículo científico publicado en 2016

Conformational modulation of in vitro activity of cyclic RGD peptides via aziridine aldehyde-driven macrocyclization chemistry.

artículo científico publicado en 2012

Cytosolic delivery of LDL nanoparticle cargo using photochemical internalization.

artículo científico publicado en 2011

Effect of removing Kupffer cells on nanoparticle tumor delivery.

artículo científico publicado en 2017

Efficient Systemic Delivery of siRNA by Using High-Density Lipoprotein-Mimicking Peptide Lipid Nanoparticles ⬇️

artículo científico publicado el 26 de julio de 2012

Efficient cytosolic delivery of siRNA using HDL-mimicking nanoparticles.

artículo científico publicado en 2011

Evaluation of Novel Imaging Devices for Nanoparticle-Mediated Fluorescence-Guided Lung Tumor Therapy

scientific article published on 08 February 2019

FRET quenching of photosensitizer singlet oxygen generation

artículo científico publicado en 2009

Facile Synthesis of Advanced Photodynamic Molecular Beacon Architectures

artículo científico publicado en 2010

HDL-mimicking peptide-lipid nanoparticles with improved tumor targeting

artículo científico publicado en 2010

Imaging of specific activation of photodynamic molecular beacons in breast cancer vertebral metastases

artículo científico publicado en 2011

Imaging the cytosolic drug delivery mechanism of HDL-like nanoparticles.

artículo científico publicado en 2013

Investigating the impact of nanoparticle size on active and passive tumor targeting efficiency.

artículo científico publicado en 2014

Investigating the specific uptake of EGF-conjugated nanoparticles in lung cancer cells using fluorescence imaging.

artículo científico publicado en 2010

Killer beacons for combined cancer imaging and therapy.

artículo científico publicado en 2007

Learning from biology: synthetic lipoproteins for drug delivery

artículo científico publicado en 2014

Ligand conjugated low-density lipoprotein nanoparticles for enhanced optical cancer imaging in vivo.

artículo científico publicado en 2007

Lipid-based nanoparticles in the systemic delivery of siRNA.

artículo científico

Lipoprotein nanoplatform for targeted delivery of diagnostic and therapeutic agents

artículo científico publicado en 2009

Lipoprotein-based nanoparticles rescue the memory loss of mice with Alzheimer's disease by accelerating the clearance of amyloid-beta

artículo científico publicado en 2014

Long-Circulating Prostate-Specific Membrane Antigen-Targeted NIR Phototheranostic Agent

artículo científico publicado en 2019

Low-density lipoprotein nanoparticles as magnetic resonance imaging contrast agents

artículo científico publicado en 2006

Matrix metalloproteinase-based photodynamic molecular beacons for targeted destruction of bone metastases in vivo

artículo científico publicado en 2016

Mixed and Matched Metallo-Nanotexaphyrin for Customizable Biomedical Imaging

artículo científico publicado en 2018

Modulation of reactive oxygen species photogeneration of bacteriopheophorbide a derivatives by exocyclic E-ring opening and charge modifications.

artículo científico publicado en 2013

Molecular imaging in drug development: Update and challenges for radiolabeled antibodies and nanotechnology.

artículo científico publicado en 2017

Multimodal Image-Guided Surgical and Photodynamic Interventions in Head and Neck Cancer: From Primary Tumor to Metastatic Drainage

artículo científico publicado en 2015

Multimodal Nanoparticle for Primary Tumor Delineation and Lymphatic Metastasis Mapping in a Head-and-Neck Cancer Rabbit Model

artículo científico publicado en 2015

Multimodal bacteriochlorophyll theranostic agent.

artículo científico publicado en 2011

Multipronged Biomimetic Approach To Create Optically Tunable Nanoparticles

scientific article published on 06 June 2018

Nanoparticle targeted folate receptor 1-enhanced photodynamic therapy for lung cancer.

artículo científico publicado en 2017

Nanoparticle-Enabled Selective Destruction of Prostate Tumor Using MRI-Guided Focal Photothermal Therapy

artículo científico publicado en 2016

Nanoparticle-enabled, image-guided treatment planning of target specific RNAi therapeutics in an orthotopic prostate cancer model.

artículo científico publicado en 2014

Nanostructure‐Driven Indocyanine Green Dimerization Generates Ultra‐Stable Phototheranostics Nanoparticles

artículo científico publicado en 2023

Nanotexaphyrin: One-Pot Synthesis of a Manganese Texaphyrin-Phospholipid Nanoparticle for Magnetic Resonance Imaging

artículo científico publicado en 2016

Naphthalocyanine-reconstituted LDL nanoparticles for in vivo cancer imaging and treatment.

artículo científico publicado en 2007

Optical glucose analogs of aminolevulinic acid for fluorescence-guided tumor resection and photodynamic therapy

artículo científico publicado en 2014

Organized Aggregation of Porphyrins in Lipid Bilayers for Third Harmonic Generation Microscopy.

artículo científico publicado en 2015

Peptide-based molecular beacons for cancer imaging and therapy.

scientific article published on 19 February 2010

Peptide-based pharmacomodulation of a cancer-targeted optical imaging and photodynamic therapy agent.

artículo científico publicado en 2007

Personalized siRNA-Nanoparticle Systemic Therapy using Metastatic Lymph Node Specimens Obtained with EBUS-TBNA in Lung Cancer.

artículo científico publicado en 2017

Photodynamic molecular beacon as an activatable photosensitizer based on protease-controlled singlet oxygen quenching and activation

artículo científico publicado en 2007

Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers

scientific article published on January 2009

Photodynamic therapy enables tumor-specific ablation in preclinical models of thyroid cancer

artículo científico publicado en 2020

Phototheranostic Porphyrin Nanoparticles Enable Visualization and Targeted Treatment of Head and Neck Cancer in Clinically Relevant Models.

artículo científico publicado en 2015

Porphyrin FRET Acceptors for Apoptosis Induction and Monitoring

scientific article published on 28 October 2011

Porphyrin Nanodroplets: Sub-micrometer Ultrasound and Photoacoustic Contrast Imaging Agents

artículo científico publicado en 2015

Porphyrin-lipid stabilized paclitaxel nanoemulsion for combined photodynamic therapy and chemotherapy

artículo científico publicado en 2021

PorphyrinHDL: A Novel Photosensitizing Nanoparticle for Lung Cancer Therapy

artículo científico publicado en 2018

Porphysome nanoparticles for enhanced photothermal therapy in a patient-derived orthotopic pancreas xenograft cancer model: a pilot study

article

Preclinical investigation of folate receptor-targeted nanoparticles for photodynamic therapy of malignant pleural mesothelioma

artículo científico publicado en 2018

Protease-triggered photosensitizing beacon based on singlet oxygen quenching and activation

artículo científico publicado en 2004

QUANTIFYING NANOPARTICLE TRANSPORT IN VIVO USING HYPERSPECTRAL IMAGING WITH A DORSAL SKINFOLD WINDOW CHAMBER.

artículo científico publicado en 2012

Stable J-Aggregation of an aza-BODIPY-Lipid in a Liposome for Optical Cancer Imaging

artículo científico publicado en 2019

Stable J-aggregation enabled dual photoacoustic and fluorescence nanoparticles for intraoperative cancer imaging

artículo científico publicado en 2016

Subtherapeutic Photodynamic Treatment Facilitates Tumor Nanomedicine Delivery and Overcomes Desmoplasia

artículo científico publicado en 2020

Synthesis and evaluation of a stable bacteriochlorophyll-analog and its incorporation into high-density lipoprotein nanoparticles for tumor imaging.

artículo científico publicado en 2009

Tailored theranostic apolipoprotein E3 porphyrin-lipid nanoparticles target glioblastoma.

artículo científico publicado en 2017

Tailoring Porphyrin Conjugation for Nanoassembly-Driven Phototheranostic Properties

scientific article published on 01 April 2019

Tailoring nanoparticle designs to target cancer based on tumor pathophysiology.

artículo científico publicado en 2016

Targeting-triggered porphysome nanostructure disruption for activatable photodynamic therapy.

artículo científico publicado en 2014

The dose threshold for nanoparticle tumour delivery

artículo científico publicado en 2020

Theranostic lipid nanoparticles for cancer medicine.

artículo científico

Topical MMP beacon enabled fluorescence-guided resection of oral carcinoma

artículo científico publicado en 2016

Transforming a Targeted Porphyrin Theranostic Agent into a PET Imaging Probe for Cancer.

artículo científico publicado en 2011

Use of Porphysomes to detect primary tumour, lymph node metastases, intra-abdominal metastases and as a tool for image-guided lymphadenectomy: proof of concept in endometrial cancer

artículo científico publicado en 2019

Using Fluorescence Imaging to Track Drug Delivery and Guide Treatment Planning In Vivo

artículo científico publicado en 2016

Using molecular beacons for cancer imaging and treatment

artículo científico publicado en 2007

Using the singlet oxygen scavenging property of carotenoid in photodynamic molecular beacons to minimize photodamage to non-targeted cells

artículo científico publicado en 2007

Lista de obras de Juan Chen

"Zipper" molecular beacons: a generalized strategy to optimize the performance of activatable protease probes

A Nanoemulsion with A Porphyrin Shell for Cancer Theranostics

A PEGylation-Free Biomimetic Porphyrin Nanoplatform for Personalized Cancer Theranostics

A tumor mRNA-triggered photodynamic molecular beacon based on oligonucleotide hairpin control of singlet oxygen production

Ablation of hypoxic tumors with dose-equivalent photothermal, but not photodynamic, therapy using a nanostructured porphyrin assembly

Activatable photosensitizers for imaging and therapy.

Activation Kinetics of Zipper Molecular Beacons

Attenuation of nontargeted cell-kill using a high-density lipoprotein-mimicking peptide--phospholipid nanoscaffold.

Biologically-targeted detection of primary and micro-metastatic ovarian cancer

Biomimetic nanocarrier for direct cytosolic drug delivery.

Chlorosome-Inspired Synthesis of Templated Metallochlorin-Lipid Nanoassemblies for Biomedical Applications

Conformational modulation of in vitro activity of cyclic RGD peptides via aziridine aldehyde-driven macrocyclization chemistry.

Cytosolic delivery of LDL nanoparticle cargo using photochemical internalization.

Effect of removing Kupffer cells on nanoparticle tumor delivery.

Efficient Systemic Delivery of siRNA by Using High-Density Lipoprotein-Mimicking Peptide Lipid Nanoparticles ⬇️

Efficient cytosolic delivery of siRNA using HDL-mimicking nanoparticles.

Evaluation of Novel Imaging Devices for Nanoparticle-Mediated Fluorescence-Guided Lung Tumor Therapy

FRET quenching of photosensitizer singlet oxygen generation

Facile Synthesis of Advanced Photodynamic Molecular Beacon Architectures

HDL-mimicking peptide-lipid nanoparticles with improved tumor targeting

Imaging of specific activation of photodynamic molecular beacons in breast cancer vertebral metastases

Imaging the cytosolic drug delivery mechanism of HDL-like nanoparticles.

Investigating the impact of nanoparticle size on active and passive tumor targeting efficiency.

Investigating the specific uptake of EGF-conjugated nanoparticles in lung cancer cells using fluorescence imaging.

Killer beacons for combined cancer imaging and therapy.

Learning from biology: synthetic lipoproteins for drug delivery

Ligand conjugated low-density lipoprotein nanoparticles for enhanced optical cancer imaging in vivo.

Lipid-based nanoparticles in the systemic delivery of siRNA.

Lipoprotein nanoplatform for targeted delivery of diagnostic and therapeutic agents

Lipoprotein-based nanoparticles rescue the memory loss of mice with Alzheimer's disease by accelerating the clearance of amyloid-beta

Long-Circulating Prostate-Specific Membrane Antigen-Targeted NIR Phototheranostic Agent

Low-density lipoprotein nanoparticles as magnetic resonance imaging contrast agents

Matrix metalloproteinase-based photodynamic molecular beacons for targeted destruction of bone metastases in vivo

Mixed and Matched Metallo-Nanotexaphyrin for Customizable Biomedical Imaging

Modulation of reactive oxygen species photogeneration of bacteriopheophorbide a derivatives by exocyclic E-ring opening and charge modifications.

Molecular imaging in drug development: Update and challenges for radiolabeled antibodies and nanotechnology.

Multimodal Image-Guided Surgical and Photodynamic Interventions in Head and Neck Cancer: From Primary Tumor to Metastatic Drainage

Multimodal Nanoparticle for Primary Tumor Delineation and Lymphatic Metastasis Mapping in a Head-and-Neck Cancer Rabbit Model

Multimodal bacteriochlorophyll theranostic agent.

Multipronged Biomimetic Approach To Create Optically Tunable Nanoparticles

Nanoparticle targeted folate receptor 1-enhanced photodynamic therapy for lung cancer.

Nanoparticle-Enabled Selective Destruction of Prostate Tumor Using MRI-Guided Focal Photothermal Therapy

Nanoparticle-enabled, image-guided treatment planning of target specific RNAi therapeutics in an orthotopic prostate cancer model.

Nanostructure‐Driven Indocyanine Green Dimerization Generates Ultra‐Stable Phototheranostics Nanoparticles

Nanotexaphyrin: One-Pot Synthesis of a Manganese Texaphyrin-Phospholipid Nanoparticle for Magnetic Resonance Imaging

Naphthalocyanine-reconstituted LDL nanoparticles for in vivo cancer imaging and treatment.

Optical glucose analogs of aminolevulinic acid for fluorescence-guided tumor resection and photodynamic therapy

Organized Aggregation of Porphyrins in Lipid Bilayers for Third Harmonic Generation Microscopy.

Peptide-based molecular beacons for cancer imaging and therapy.

Peptide-based pharmacomodulation of a cancer-targeted optical imaging and photodynamic therapy agent.

Personalized siRNA-Nanoparticle Systemic Therapy using Metastatic Lymph Node Specimens Obtained with EBUS-TBNA in Lung Cancer.

Photodynamic molecular beacon as an activatable photosensitizer based on protease-controlled singlet oxygen quenching and activation

Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers

Photodynamic therapy enables tumor-specific ablation in preclinical models of thyroid cancer

Phototheranostic Porphyrin Nanoparticles Enable Visualization and Targeted Treatment of Head and Neck Cancer in Clinically Relevant Models.

Porphyrin FRET Acceptors for Apoptosis Induction and Monitoring

Porphyrin Nanodroplets: Sub-micrometer Ultrasound and Photoacoustic Contrast Imaging Agents

Porphyrin-lipid stabilized paclitaxel nanoemulsion for combined photodynamic therapy and chemotherapy

PorphyrinHDL: A Novel Photosensitizing Nanoparticle for Lung Cancer Therapy

Porphysome nanoparticles for enhanced photothermal therapy in a patient-derived orthotopic pancreas xenograft cancer model: a pilot study

Preclinical investigation of folate receptor-targeted nanoparticles for photodynamic therapy of malignant pleural mesothelioma

Protease-triggered photosensitizing beacon based on singlet oxygen quenching and activation

QUANTIFYING NANOPARTICLE TRANSPORT IN VIVO USING HYPERSPECTRAL IMAGING WITH A DORSAL SKINFOLD WINDOW CHAMBER.

Stable J-Aggregation of an aza-BODIPY-Lipid in a Liposome for Optical Cancer Imaging

Stable J-aggregation enabled dual photoacoustic and fluorescence nanoparticles for intraoperative cancer imaging

Subtherapeutic Photodynamic Treatment Facilitates Tumor Nanomedicine Delivery and Overcomes Desmoplasia

Synthesis and evaluation of a stable bacteriochlorophyll-analog and its incorporation into high-density lipoprotein nanoparticles for tumor imaging.

Tailored theranostic apolipoprotein E3 porphyrin-lipid nanoparticles target glioblastoma.

Tailoring Porphyrin Conjugation for Nanoassembly-Driven Phototheranostic Properties

Tailoring nanoparticle designs to target cancer based on tumor pathophysiology.

Targeting-triggered porphysome nanostructure disruption for activatable photodynamic therapy.

The dose threshold for nanoparticle tumour delivery

Theranostic lipid nanoparticles for cancer medicine.

Topical MMP beacon enabled fluorescence-guided resection of oral carcinoma

Transforming a Targeted Porphyrin Theranostic Agent into a PET Imaging Probe for Cancer.

Use of Porphysomes to detect primary tumour, lymph node metastases, intra-abdominal metastases and as a tool for image-guided lymphadenectomy: proof of concept in endometrial cancer

Using Fluorescence Imaging to Track Drug Delivery and Guide Treatment Planning In Vivo

Using molecular beacons for cancer imaging and treatment

Using the singlet oxygen scavenging property of carotenoid in photodynamic molecular beacons to minimize photodamage to non-targeted cells