Lista de obras - Jana Janockova - Dominio Público Uruguay

Assessment of DNA-binding affinity of cholinesterase reactivators and electrophoretic determination of their effect on topoisomerase I and II activity.

artículo científico publicado en 2016

Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation

artículo científico publicado en 2016

Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer's disease treatment

artículo científico publicado en 2016

In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers

artículo científico publicado en 2019

Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds.

artículo científico publicado en 2015

Interaction of cholinesterase modulators with DNA and their cytotoxic activity.

artículo científico publicado en 2013

Investigation of New Orexin 2 Receptor Modulators Using and In Vitro Methods

artículo científico publicado en 2018

Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases.

artículo científico publicado en 2017

N-alkylated Tacrine Derivatives as Potential Agents in Alzheimer's Disease Therapy

artículo científico publicado en 2019

New spiro tria(thia)zolidine-acridines as topoisomerase inhibitors, DNA binders and cytostatic compounds

artículo científico publicado en 2016

Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer's Agents: Design, Synthesis and Biological Evaluation.

artículo científico publicado en 2017

Novel cholinesterase modulators and their ability to interact with DNA.

artículo científico publicado en 2013

Orexin supplementation in narcolepsy treatment: A review

scientific article published on 14 November 2018

Profiling donepezil template into multipotent hybrids with antioxidant properties.

artículo científico publicado en 2018

Proliferation inhibition of novel diphenylamine derivatives

scientific article published on 02 November 2018

Rational design of novel TLR4 ligands by in silico screening and their functional and structural characterization in vitro.

artículo científico publicado en 2018

Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives

scientific article published on 26 June 2019

Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease.

artículo científico publicado en 2016

Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy

artículo científico publicado en 2019

Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment

artículo científico publicado en 2016

Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase

artículo científico publicado en 2019

Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors.

artículo científico publicado en 2015

Tacrine-coumarin and Tacrine-7-chloroquinoline Hybrids with Thiourea Linkers: Cholinesterase Inhibition Properties, Kinetic Study, Molecular Docking and Permeability Assay for Blood-brain Barrier

artículo científico publicado en 2018

Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapy

artículo científico publicado en 2016

The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators

artículo científico publicado en 2016

Lista de obras de Jana Janockova

Assessment of DNA-binding affinity of cholinesterase reactivators and electrophoretic determination of their effect on topoisomerase I and II activity.

Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation

Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer's disease treatment

In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers

Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds.

Interaction of cholinesterase modulators with DNA and their cytotoxic activity.

Investigation of New Orexin 2 Receptor Modulators Using and In Vitro Methods

Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases.

N-alkylated Tacrine Derivatives as Potential Agents in Alzheimer's Disease Therapy

New spiro tria(thia)zolidine-acridines as topoisomerase inhibitors, DNA binders and cytostatic compounds

Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer's Agents: Design, Synthesis and Biological Evaluation.

Novel cholinesterase modulators and their ability to interact with DNA.

Orexin supplementation in narcolepsy treatment: A review

Profiling donepezil template into multipotent hybrids with antioxidant properties.

Proliferation inhibition of novel diphenylamine derivatives

Rational design of novel TLR4 ligands by in silico screening and their functional and structural characterization in vitro.

Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives

Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease.

Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy

Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment

Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase

Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors.

Tacrine-coumarin and Tacrine-7-chloroquinoline Hybrids with Thiourea Linkers: Cholinesterase Inhibition Properties, Kinetic Study, Molecular Docking and Permeability Assay for Blood-brain Barrier

Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapy

The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators