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Lista de obras de Gautam Sethi

'Lnc'-ing Wnt in female reproductive cancers: therapeutic potential of long non-coding RNAs in Wnt signalling.

artículo científico publicado en 2017

6-Shogaol exerts anti-proliferative and pro-apoptotic effects through the modulation of STAT3 and MAPKs signaling pathways.

artículo científico publicado en 2014

A brief update on potential molecular mechanisms underlying antimicrobial and wound-healing potency of snake venom molecules.

artículo científico publicado en 2016

A facile assay to monitor secretory phospholipase A₂ using 8-anilino-1-naphthalenesulfonic acid

artículo científico publicado en 2014

A novel 4,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazole derivative inhibits tumor cell invasion and potentiates the apoptotic effect of TNFα by abrogating NF-κB activation cascade

artículo científico publicado en 2016

A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma

artículo científico publicado en 2017

A novel combinatorial strategy using Seliciclib(®) and Belinostat(®) for eradication of non-small cell lung cancer via apoptosis induction and BID activation

artículo científico publicado en 2016

A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells

artículo científico publicado en 2006

ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and c-Myc to reduce breast cancer proliferation

artículo científico publicado en 2016

Aberrant lysine acetylation in tumorigenesis: Implications in the development of therapeutics

artículo científico publicado en 2016

Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model.

artículo científico publicado en 2014

Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM-p73 mediated apoptosis in oral squamous cell carcinoma.

artículo científico publicado en 2017

Activation of c-Jun N-terminal kinase is required for ultraviolet B-induced apoptosis of murine peritoneal macrophages in vitro

artículo científico publicado en 2004

Adamantyl-tethered-biphenylic compounds induce apoptosis in cancer cells by targeting Bcl homologs

artículo científico publicado en 2015

Ageing and the telomere connection: An intimate relationship with inflammation

artículo científico publicado en 2015

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.

artículo científico publicado en 2013

Analysis of the intricate relationship between chronic inflammation and cancer.

artículo científico

Animal venoms as antimicrobial agents.

artículo científico publicado en 2017

Annexin-A1 controls an ERK-RhoA-NFκB activation loop in breast cancer cells.

artículo científico publicado en 2015

Annexin-A1 regulates microRNA-26b* and microRNA-562 to directly target NF-κB and angiogenesis in breast cancer cells.

artículo científico publicado en 2014

Anti-Inflammatory activity of Angelica keiskei through suppression of mitogen-activated protein kinases and nuclear factor-kappaB activation pathways.

artículo científico publicado en 2010

Anti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives

artículo científico publicado en 2012

Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway.

artículo científico publicado en 2011

Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its development

artículo científico publicado en 2016

Artesunate suppresses tumor growth and induces apoptosis through the modulation of multiple oncogenic cascades in a chronic myeloid leukemia xenograft mouse model

artículo científico publicado en 2015

Ascochlorin Enhances the Sensitivity of Doxorubicin Leading to the Reversal of Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma

artículo científico publicado en 2016

Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3.

artículo científico publicado en 2015

Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.

artículo científico publicado en 2008

Bergamottin, a natural furanocoumarin obtained from grapefruit juice induces chemosensitization and apoptosis through the inhibition of STAT3 signaling pathway in tumor cells

artículo científico publicado en 2014

Bioactive natural products in cancer prevention and therapy: Progress and promise

artículo científico publicado en 2016

Biopharmacological considerations for accelerating drug development of deguelin, a rotenoid with potent chemotherapeutic and chemopreventive potential

scientific article published on 01 April 2019

Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel

artículo científico publicado en 2015

Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4.

artículo científico publicado en 2017

Butein and Its Role in Chronic Diseases.

artículo científico publicado en 2016

Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells.

artículo científico publicado en 2010

Butein in health and disease: A comprehensive review

artículo científico publicado en 2016

Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue

artículo científico publicado en 2007

Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds.

artículo científico publicado en 2016

Capillarisin inhibits constitutive and inducible STAT3 activation through induction of SHP-1 and SHP-2 tyrosine phosphatases

artículo científico publicado en 2013

Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancer

artículo científico publicado en 2016

Cardamonin represses proliferation, invasion, and causes apoptosis through the modulation of signal transducer and activator of transcription 3 pathway in prostate cancer

artículo científico publicado en 2016

Casticin inhibits growth and enhances ionizing radiation-induced apoptosis through the suppression of STAT3 signaling cascade

artículo científico publicado en 2018

Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells.

artículo científico publicado en 2011

Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways ⬇️

artículo científico publicado el 1 de octubre de 2011

Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo

artículo científico publicado en 2012

Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation

artículo científico publicado en 2007

Cellular Uptake of Ginsenosides in Korean White Ginseng and Red Ginseng and Their Apoptotic Activities in Human Breast Cancer Cells ⬇️

artículo científico publicado el 28 de julio de 2010

Chalepin: isolated from Ruta angustifolia L. Pers induces mitochondrial mediated apoptosis in lung carcinoma cells

artículo científico publicado en 2016

Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5α-reductase and extracellular signal-regulated kinase

artículo científico publicado en 2016

Combined use of irinotecan with histone deacetylase inhibitor belinostat could cause severe toxicity by inhibiting SN-38 glucuronidation via UGT1A1.

artículo científico publicado en 2017

Conditioned media from adipocytes promote proliferation, migration, and invasion in melanoma and colorectal cancer cells

artículo científico publicado en 2019

Corilagin in Cancer: A Critical Evaluation of Anticancer Activities and Molecular Mechanisms

scientific article published on 19 September 2019

Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model

artículo científico publicado en 2009

Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in IFN-alpha-sensitive and IFN-alpha-resistant human bladder cance

artículo científico publicado en 2007

Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism.

artículo científico publicado en 2007

Curcumin: getting back to the roots.

artículo científico publicado en 2005

DEAD-box helicase DP103 defines metastatic potential of human breast cancers

artículo científico publicado en 2014

Deficiency of NRH:quinone oxidoreductase 2 differentially regulates TNF signaling in keratinocytes: up-regulation of apoptosis correlates with down-regulation of cell survival kinases

artículo científico publicado en 2007

Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action

artículo científico publicado en 2015

Design and synthesis of benzimidazole-based Rho kinase inhibitors for the treatment of glaucoma

artículo científico publicado en 2017

Development of Novel Triazolo-Thiadiazoles from Heterogeneous "Green" Catalysis as Protein Tyrosine Phosphatase 1B Inhibitors

artículo científico publicado en 2015

Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo

artículo científico publicado en 2014

Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells.

artículo científico publicado en 2010

Do STAT3 inhibitors have potential in the future for cancer therapy?

artículo científico publicado en 2017

Dual role of autophagy in hallmarks of cancer.

artículo científico publicado en 2017

Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades.

artículo científico publicado en 2012

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

artículo científico publicado en 2013

Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma

artículo científico publicado en 2013

Epidermal growth factor (EGF) activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkappaBalpha

artículo científico publicado en 2007

Epidermal growth factor (EGF) activates nuclear factor-κB through IκBα kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IκBα.

artículo científico publicado en 2015

Evidence that genetic deletion of the TNF receptor p60 or p80 inhibits Fas mediated apoptosis in macrophages

scientific article published on 10 July 2007

Exosome-Mediated Metastasis: From Epithelial-Mesenchymal Transition to Escape from Immunosurveillance

artículo científico publicado en 2016

Expression of NF-kappaB parallels COX-2 expression in oral precancer and cancer: association with smokeless tobacco.

artículo científico

Farnesol inhibits tumor growth and enhances the anticancer effects of bortezomib in multiple myeloma xenograft mouse model through the modulation of STAT3 signaling pathway.

artículo científico publicado en 2015

First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway.

artículo científico publicado en 2012

Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells

artículo científico publicado en 2016

Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances ap

artículo científico publicado en 2008

From traditional Ayurvedic medicine to modern medicine: identification of therapeutic targets for suppression of inflammation and cancer.

artículo científico publicado en 2006

Functional characterization of selective exosite-binding inhibitors of matrix metalloproteinase-13 (MMP-13) - experimental validation in human breast and colon cancer

artículo científico publicado en 2016

Functionalized tetrahydro-1H-pyrido[4,3-b]indoles: a novel chemotype with Sirtuin 2 inhibitory activity

artículo científico publicado en 2014

Gamma Radiation-Induced Disruption of Cellular Junctions in HUVECs Is Mediated through Affecting MAPK/NF-κB Inflammatory Pathways

scientific article published on 04 August 2019

Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis.

artículo científico publicado en 2006

Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers.

artículo científico publicado en 2015

Garcinol, a polyisoprenylated benzophenone modulates multiple proinflammatory signaling cascades leading to the suppression of growth and survival of head and neck carcinoma

artículo científico publicado en 2013

Garcinol: Current status of its anti-oxidative, anti-inflammatory and anti-cancer effects.

artículo científico

Gene Microarray Analyses of Daboia russelli russelli Daboiatoxin Treatment of THP-1 Human Macrophages Infected with Burkholderia pseudomallei.

artículo científico publicado en 2015

Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis

artículo científico publicado en 2006

Ginkgolic Acid C 17:1, Derived from Ginkgo biloba Leaves, Suppresses Constitutive and Inducible STAT3 Activation through Induction of PTEN and SHP-1 Tyrosine Phosphatase.

artículo científico publicado en 2017

Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products. ⬇️

artículo científico publicado en 2007

Guggulsterone, a farnesoid X receptor antagonist, inhibits constitutive and inducible STAT3 activation through induction of a protein tyrosine phosphatase SHP-1.

artículo científico publicado en 2008

Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway

scientific article published on 01 September 2006

Identification of a novel Calotropis procera protein that can suppress tumor growth in breast cancer through the suppression of NF-κB pathway

artículo científico publicado en 2012

Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.

artículo científico publicado en 2010

Identification of natural peptides as a new class of antimalarial drugs by in silico approaches

artículo científico publicado en 2017

Identification of novel peroxisome proliferator-activated receptor-gamma (PPARγ) agonists using molecular modeling method.

artículo científico publicado en 2014

In vitro activation of murine peritoneal macrophages by ultraviolet B radiation: upregulation of CD18, production of NO, proinflammatory cytokines and a signal transduction pathway.

artículo científico publicado en 2004

Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway.

artículo científico publicado en 2006

Inflammation and cancer: how hot is the link?

artículo científico publicado en 2006

Influenza A virus enhances its propagation through the modulation of Annexin-A1 dependent endosomal trafficking and apoptosis.

artículo científico publicado en 2016

Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model

artículo científico publicado en 2011

Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

artículo científico publicado en 2014

Inhibition of p300 lysine acetyltransferase activity by luteolin reduces tumor growth in head and neck squamous cell carcinoma (HNSCC) xenograft mouse model

artículo científico publicado en 2015

Involvement of MAP kinase signal transduction pathway in UVB-induced activation of macrophages in vitro.

artículo científico publicado en 2003

Involvement of fas/fas ligand in ultraviolet B-induced apoptosis of murine peritoneal macrophages.

artículo científico publicado en 2004

Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer.

artículo científico publicado en 2015

Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer.

artículo científico publicado en 2012

Isorhynchophylline, a Potent Plant Alkaloid, Induces Apoptotic and Anti-Metastatic Effects in Human Hepatocellular Carcinoma Cells through the Modulation of Diverse Cell Signaling Cascades.

artículo científico publicado en 2017

Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and Perspectives

artículo científico publicado en 2016

Key cell signaling pathways modulated by zerumbone: role in the prevention and treatment of cancer.

artículo científico

LDL cholesterol promotes the proliferation of prostate and pancreatic cancer cells by activating the STAT3 pathway

artículo científico publicado en 2020

Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases

artículo científico publicado en 2019

Melioidosis: Clinical impact and public health threat in the tropics.

artículo científico publicado en 2017

Mending the bones with natural products

artículo científico publicado en 2007

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn.

artículo científico publicado en 2017

Molecular Targets of Ascochlorin and Its Derivatives for Cancer Therapy

artículo científico publicado en 2017

Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements

scientific article published on 12 February 2020

Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer.

artículo científico publicado en 2010

Morin (3,5,7,2',4'-Pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosis

artículo científico publicado en 2007

Multifaceted link between cancer and inflammation ⬇️

artículo científico publicado el 1 de febrero de 2012

N'-Alkylaminosulfonyl Analogues of 6-Fluorobenzylideneindolinones with Desirable Physicochemical Profiles and Potent Growth Inhibitory Activities on Hepatocellular Carcinoma.

artículo científico publicado en 2015

NF-κB in cancer therapy.

artículo científico publicado en 2015

NMR Structure of Carcinoscorpius rotundicauda Thioredoxin-related Protein 16 and Its Role in Regulating Transcription Factor NF-κB Activity ⬇️

artículo científico publicado el 3 de julio de 2012

Natural bioactives and phytochemicals serve in cancer treatment and prevention.

artículo científico publicado en 2013

Natural bioactives in cancer treatment and prevention

artículo científico publicado en 2015

Natural products as a gold mine for arthritis treatment.

artículo científico publicado en 2007

Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells.

artículo científico publicado en 2014

Neuronal Development-Related miRNAs as Biomarkers for Alzheimer's disease, Depression, Schizophrenia and Ionizing Radiation Exposure

scientific article published on 21 January 2020

Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model.

artículo científico publicado en 2015

Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo

artículo científico publicado en 2016

Novel medicines and strategies in cancer treatment and prevention

artículo científico publicado en 2014

Novel phospholipase A2 inhibitors from python serum are potent peptide antibiotics.

artículo científico publicado en 2015

Novel synthetic biscoumarins target tumor necrosis factor-α in hepatocellular carcinoma in vitro and in vivo

artículo científico publicado en 2014

Novel synthetic coumarins that targets NF-κB in Hepatocellular carcinoma

artículo científico publicado en 2014

Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1.

artículo científico publicado en 2010

Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives.

artículo científico publicado en 2014

Oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer: preclinical and clinical evidence.

scientific article published on 30 January 2014

Oleuropein induces apoptosis via abrogating NF-κB activation cascade in estrogen receptor-negative breast cancer cells

scientific article published on 27 September 2018

Ophiopogonin D modulates multiple oncogenic signaling pathways, leading to suppression of proliferation and chemosensitization of human lung cancer cells

artículo científico publicado en 2018

Overexpression of tissue transglutaminase leads to constitutive activation of nuclear factor-kappaB in cancer cells: delineation of a novel pathway

artículo científico publicado en 2006

PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple Negative Breast Cancers

artículo científico

Pan-HDAC inhibition by panobinostat mediates chemosensitization to carboplatin in non-small cell lung cancer via attenuation of EGFR signaling

artículo científico publicado en 2018

Phytometabolites Targeting the Warburg Effect in Cancer Cells: A Mechanistic Review

artículo científico publicado en 2016

Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.

artículo científico publicado en 2008

Plant-based hydrocarbon esters from Tragia involucrata possess antimicrobial and anti-inflammatory activities.

artículo científico publicado en 2013

Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4

artículo científico publicado en 2011

Polo-like kinase inhibitors: an emerging opportunity for cancer therapeutics.

artículo científico publicado en 2010

Potent anti-inflammatory activity of ursolic acid, a triterpenoid antioxidant, is mediated through suppression of NF-κB, AP-1 and NF-AT

artículo científico publicado en 2012

Potential Benefits of Edible Berries in the Management of Aerodigestive and Gastrointestinal Tract Cancers: Preclinical and Clinical Evidence.

artículo científico

Potential Protective Effects of Ursolic Acid against Gamma Irradiation-Induced Damage Are Mediated through the Modulation of Diverse Inflammatory Mediators.

artículo científico publicado en 2017

Potential Role of Natural Compounds as Anti-Angiogenic Agents in Cancer

artículo científico publicado en 2017

Potential of neem (Azadirachta indica L.) for prevention and treatment of oncologic diseases

artículo científico publicado en 2016

Potential role of targeted therapies in the treatment of triple-negative breast cancer.

artículo científico

Probiotic Lactobacillus reuteri promotes TNF-induced apoptosis in human myeloid leukemia-derived cells by modulation of NF-kappaB and MAPK signalling

artículo científico publicado en 2008

Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells.

artículo científico publicado en 2016

Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells.

artículo científico publicado en 2006

Retraction notice to "Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines" [Biochem. Pharmacol. 73 (2007) 1024

artículo científico publicado en 2016

SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IkappaBalpha kinase activation

artículo científico publicado en 2008

SREBP-1c as a molecular bridge between lipogenesis and cell cycle progression of clear cell renal carcinoma.

artículo científico publicado en 2017

Silymarin and hepatocellular carcinoma: a systematic, comprehensive, and critical review.

artículo científico publicado en 2015

Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products.

artículo científico publicado en 2014

Simvastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, suppresses osteoclastogenesis induced by receptor activator of nuclear factor-kappaB ligand through modulation of NF-kappaB pathway.

artículo científico publicado en 2008

Snake venom phospholipases A(2): a novel tool against bacterial diseases.

artículo científico publicado en 2012

Suppression of signal transducer and activator of transcription 3 activation by butein inhibits growth of human hepatocellular carcinoma in vivo

scientific article published on 03 December 2010

Synthetic Lethality of a Novel Small Molecule Against Mutant KRAS-Expressing Cancer Cells Involves AKT-Dependent ROS Production

artículo científico publicado en 2015

TNF-alpha-induced mitochondrial alterations in human T cells requires FADD and caspase-8 activation but not RIP and caspase-3 activation

artículo científico publicado en 2010

TNF: a master switch for inflammation to cancer

artículo científico publicado en 2008

Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer.

artículo científico publicado en 2013

Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: potential role in prevention and therapy of cancer

artículo científico publicado en 2012

Targeting PPARγSignaling Cascade for the Prevention and Treatment of Prostate Cancer ⬇️

artículo científico publicado el 14 de noviembre de 2012

Targeting TNF for Treatment of Cancer and Autoimmunity

artículo científico publicado en 2009

Targeting TNF-related apoptosis-inducing ligand (TRAIL) receptor by natural products as a potential therapeutic approach for cancer therapy

artículo científico publicado en 2015

Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention.

artículo científico publicado en 2017

Targeting arachidonic acid pathway by natural products for cancer prevention and therapy.

artículo científico publicado en 2016

Targeting autophagy using natural compounds for cancer prevention and therapy

scientific article published on 12 February 2019

Targeting cell signaling and apoptotic pathways by dietary agents: role in the prevention and treatment of cancer.

artículo científico publicado en 2011

Targeting multiple oncogenic pathways for the treatment of hepatocellular carcinoma

artículo científico publicado en 2016

Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis.

artículo científico publicado en 2008

Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution

artículo científico publicado en 2006

Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

artículo científico publicado en 2015

Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors.

artículo científico publicado en 2014

Targeting transcription factor NF-kappaB to overcome chemoresistance and radioresistance in cancer therapy.

scientific article published on 14 January 2010

Targeting transcription factor STAT3 for cancer prevention and therapy.

artículo científico publicado en 2015

The Role of Resveratrol in Cancer Therapy.

artículo científico publicado en 2017

The butanol fraction of guava (Psidium cattleianum Sabine) leaf extract suppresses MMP-2 and MMP-9 expression and activity through the suppression of the ERK1/2 MAPK signaling pathway

artículo científico publicado en 2012

The multifaceted role of curcumin in cancer prevention and treatment.

artículo científico publicado en 2015

The multifaceted role of reactive oxygen species in tumorigenesis

artículo científico publicado en 2020

The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy

artículo científico publicado en 2020

The potential role of boswellic acids in cancer prevention and treatment.

artículo científico publicado en 2016

The role of hydrogen sulfide in cyclic nucleotide signaling.

artículo científico publicado en 2017

The vascular endothelium and human diseases

artículo científico publicado en 2013

The vital role of ATP citrate lyase in chronic diseases

artículo científico publicado en 2019

Therapeutic implications of toll-like receptors in peripheral neuropathic pain

artículo científico publicado en 2016

Therapeutic potential of gambogic acid, a caged xanthone, to target cancer

artículo científico publicado en 2017

Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway

artículo científico publicado en 2010

Thymoquinone inhibits tumor growth and induces apoptosis in a breast cancer xenograft mouse model: the role of p38 MAPK and ROS

artículo científico publicado en 2013

Thymoquinone: potential cure for inflammatory disorders and cancer

artículo científico publicado en 2011

Tocotrienols: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics

artículo científico publicado en 2017

Traditional Chinese Medicine in Neuroprotection after Brain Insults with Special Reference to Radioprotection

article

Triple negative breast cancer in Asia: An insider's view

artículo científico publicado en 2017

Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway

artículo científico publicado en 2016

Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies.

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