Lista de obras - James Briscoe - Dominio Público Uruguay

A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.

artículo científico publicado en 1997

A fluorescent reporter of caspase activity for live imaging

artículo científico publicado en 2008

A focus on scope

artículo científico publicado en 2019

A gene regulatory motif that generates oscillatory or multiway switch outputs

artículo científico publicado en 2012

A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube

artículo científico publicado en 2005

A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube.

artículo científico publicado en 2001

A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube

scientific journal article

A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

artículo científico publicado en 1995

A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range.

artículo científico publicado en 2009

A shared transcriptional code orchestrates temporal patterning of the central nervous system

artículo científico publicado en 2021

A theoretical framework for the regulation of Shh morphogen-controlled gene expression

artículo científico publicado en 2014

ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis

artículo científico publicado en 2014

Agonizing Hedgehog

artículo científico publicado en 2006

An amphioxus Gli gene reveals conservation of midline patterning and the evolution of hedgehog signalling diversity in chordates

artículo científico publicado en 2007

An inducible transgene expression system for zebrafish and chick

artículo científico publicado en 2013

An interview with Olivier Pourquie

artículo científico publicado en 2010

An intuitive graphical visualization technique for the interrogation of transcriptome data

artículo científico publicado en 2011

An ode to the Node: 10 years in the life of a community blog

artículo científico publicado en 2020

Anterior Hox genes interact with components of the neural crest specification network to induce neural crest fates

artículo científico publicado en 2011

Applying an adaptive watershed to the tissue cell quantification during T-cell migration and embryonic development.

artículo científico publicado en 2010

Canonical BMP7 activity is required for the generation of discrete neuronal populations in the dorsal spinal cord

artículo científico publicado en 2011

Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways

artículo científico publicado en 1993

Coordination of progenitor specification and growth in mouse and chick spinal cord

artículo científico publicado en 2014

Decoding of position in the developing neural tube from antiparallel morphogen gradients.

artículo científico publicado en 2017

Developing new associations

scientific article published on 05 March 2020

Development-on-chip: in vitro neural tube patterning with a microfluidic device

artículo científico publicado en 2016

Developmental Pattern Formation in Phases.

artículo científico

Developmental pattern formation: insights from physics and biology

artículo científico publicado en 2012

Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube

artículo científico publicado en 2010

Distinct regulatory mechanisms act to establish and maintain Pax3 expression in the developing neural tube

artículo científico publicado en 2013

Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity

artículo científico publicado en 2002

Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog

artículo científico publicado en 2010

ERK1/2 signalling dynamics promote neural differentiation by regulating the polycomb repressive complex

article published in 2019

Epithelial organisation revealed by a network of cellular contacts

artículo científico publicado en 2011

Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedback

artículo científico publicado en 2009

Establishing neuronal circuitry: Hox genes make the connection.

artículo científico publicado en 2004

Establishing neuronal diversity in the spinal cord: a time and a place

scientific article published on 25 November 2019

Floor Plate Patterning of Ventral Cell Types: Ventral Patterning

scholarly article published 2009

Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development

artículo científico publicado en 2009

Foxj1 regulates floor plate cilia architecture and modifies the response of cells to sonic hedgehog signalling

artículo científico publicado en 2010

G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.

artículo científico publicado en 2018

Gene expression dysregulation domains are not a specific feature of Down syndrome

scientific article published on 06 June 2019

Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube

artículo científico publicado en 2012

Generation of mice with functional inactivation of talpid3, a gene first identified in chicken

scientific journal article

Genetics of system biology

artículo científico publicado en 2012

Gli proteins and the control of spinal-cord patterning

artículo científico publicado en 2003

Hedgehog signaling: from the Drosophila cuticle to anti-cancer drugs.

artículo científico publicado en 2005

Hedgehog signaling: measuring ligand concentrations with receptor ratios

artículo científico publicado en 2004

Hedgehog threads to spread

artículo científico publicado en 2013

Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling

scientific journal article

Homozygous Ft embryos are affected in floor plate maintenance and ventral neural tube patterning.

artículo científico publicado en 2005

Human axial progenitors generate trunk neural crest cells in vitro

scientific article published on 10 August 2018

In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity

artículo científico publicado en 2014

Inclusion and diversity in developmental biology: introducing the Node Network

artículo científico publicado en 2020

Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung's disease in Bardet-Biedl syndrome

artículo científico publicado en 2008

Inhibitory Gli3 activity negatively regulates Wnt/beta-catenin signaling

artículo científico publicado en 2007

Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain

artículo científico publicado en 2009

Integration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversity

artículo científico publicado en 2014

Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism

artículo científico publicado en 2007

Intrinsic Noise Profoundly Alters the Dynamics and Steady State of Morphogen-Controlled Bistable Genetic Switches ⬇️

artículo científico publicado en 2016

JAKs and STATs branch out.

artículo científico publicado en 1996

JAKs, STATs and signal transduction in response to the interferons and other cytokines

artículo científico publicado en 1996

Jagged2 controls the generation of motor neuron and oligodendrocyte progenitors in the ventral spinal cord.

artículo científico publicado en 2011

Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state

artículo científico publicado en 1996

Let there be preLights: one year on

artículo científico publicado en 2019

Limbs made to measure

artículo científico publicado en 2010

Local retinoic acid signaling directs emergence of the extraocular muscle functional unit

scientific article published on 17 November 2020

Looking at neurodevelopment through a big data lens

scientific article published on 01 September 2020

Making a grade: Sonic Hedgehog signalling and the control of neural cell fate

artículo científico publicado en 2009

Mathematical models help explain experimental data. Response to 'Transcriptional interpretation of Shh morphogen signaling: computational modeling validates empirically established models'.

artículo científico publicado en 2016

Memory functions reveal structural properties of gene regulatory networks.

artículo científico publicado en 2018

Morphogen interpretation: concentration, time, competence, and signaling dynamics

artículo científico publicado en 2017

Morphogen interpretation: the transcriptional logic of neural tube patterning

artículo científico

Morphogen rules: design principles of gradient-mediated embryo patterning

artículo científico publicado en 2015

Morphogens, modeling and patterning the neural tube: an interview with James Briscoe

artículo científico publicado en 2015

Mouse mutagenesis identifies novel roles for left-right patterning genes in pulmonary, craniofacial, ocular, and limb development

artículo científico publicado en 2009

Neural Progenitors Adopt Specific Identities by Directly Repressing All Alternative Progenitor Transcriptional Programs

artículo científico publicado en 2016

Neural crest development is regulated by the transcription factor Sox9.

artículo científico publicado en 2003

Neuronal differentiation affects tissue mechanics and progenitor arrangement in the vertebrate neuroepithelium

Neuronal differentiation influences progenitor arrangement in the vertebrate neuroepithelium

scientific article published on 04 December 2019

New Year PlanS

scientific article published on 04 January 2019

Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling

artículo científico publicado en 2015

Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics

artículo científico publicado en 2018

Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics

Oncogenicity of the developmental transcription factor Sox9.

artículo científico publicado en 2012

Otx2 regulates subtype specification and neurogenesis in the midbrain

scientific journal article

Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network

artículo científico publicado en 2008

Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling

scientific journal article

Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling. ⬇️

artículo científico publicado en 2013

Please allow me to introduce myself

Primary cilia and graded Sonic Hedgehog signaling

artículo científico publicado en 2012

Ptch1 and Gli regulate Shh signalling dynamics via multiple mechanisms

artículo científico publicado en 2015

Publisher Correction: c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells

article

Reduced cholesterol levels impair Smoothened activation in Smith-Lemli-Opitz syndrome.

artículo científico publicado en 2015

Regionalization of the nervous system requires axial allocation prior to neural lineage commitment

Regulation of the neural patterning activity of sonic hedgehog by secreted BMP inhibitors expressed by notochord and somites.

artículo científico publicado en 2000

Regulatory pathways linking progenitor patterning, cell fates and neurogenesis in the ventral neural tube

artículo científico publicado en 2008

Retinoid Acid Specifies Neuronal Identity through Graded Expression of Ascl1.

artículo científico publicado en 2013

Retinoid acid specifies neuronal identity through graded expression of Ascl1.

artículo científico publicado en 2013

SOX9 induces and maintains neural stem cells

scientific journal article

SUMOylation by Pias1 regulates the activity of the Hedgehog dependent Gli transcription factors

artículo científico publicado en 2010

Scaling Pattern to Variations in Size during Development of the Vertebrate Neural Tube

artículo científico publicado en 2016

Signal transduction. Just another signalling pathway.

artículo científico publicado en 1994

Singapore signalling: the 2012 hedgehog pathway cocktail

artículo científico publicado en 2012

Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

artículo científico publicado en 2019

Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

Single-cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human-specific features

artículo científico publicado en 2021

Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened

artículo científico publicado en 2011

Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation

artículo científico publicado en 2022

Species-specific pace of development is associated with differences in protein stability

artículo científico publicado en 2020

TRF2-independent chromosome end protection during pluripotency

artículo científico publicado en 2020

Temporal control of BMP signalling determines neuronal subtype identity in the dorsal neural tube.

artículo científico publicado en 2013

Temporal dynamics of patterning by morphogen gradients

scientific article published on 10 July 2009

The PAX-FOXO1s trigger fast trans-differentiation of chick embryonic neural cells into alveolar rhabdomyosarcoma with tissue invasive properties limited by S phase entry inhibition

artículo científico publicado en 2020

The Sonic hedgehog pathway independently controls the patterning, proliferation and survival of neuroepithelial cells by regulating Gli activity

artículo científico publicado en 2006

The antiviral response to gamma interferon

artículo científico publicado en 2002

The chicken talpid3 gene encodes a novel protein essential for Hedgehog signaling

artículo científico publicado en 2006

The floor plate: multiple cells, multiple signals

artículo científico publicado en 2005

The generation and diversification of spinal motor neurons: signals and responses

artículo científico publicado en 2004

The interpretation of morphogen gradients

artículo científico publicado en 2006

The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling

scientific journal article

The mechanisms of Hedgehog signalling and its roles in development and disease

artículo científico

The physics of development 100years after D'Arcy Thompson's "On Growth and Form".

artículo científico publicado en 2017

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

artículo científico publicado en 1993

The route to spinal cord cell types: a tale of signals and switches

artículo científico

The specification of neuronal identity by graded Sonic Hedgehog signalling.

artículo científico publicado en 1999

The transcriptional control of trunk neural crest induction, survival, and delamination

scientific journal article

The transcriptional repressor Glis2 is a novel binding partner for p120 catenin

scientific journal article

The transition from differentiation to growth during dermomyotome-derived myogenesis depends on temporally restricted hedgehog signaling

artículo científico publicado en 2013

Thomas M. Jessell (1951-2019)

scientific article published on 24 May 2019

Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis

scientific journal article

Valproic acid silencing of ascl1b/Ascl1 results in the failure of serotonergic differentiation in a zebrafish model of fetal valproate syndrome

scientific article published on 17 October 2013

Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates

artículo científico publicado en 2000

What does time mean in development?

article

Zooming into 2021

artículo científico publicado en 2021

c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells.

artículo científico publicado en 2018

Lista de obras de James Briscoe

A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.

A fluorescent reporter of caspase activity for live imaging

A focus on scope

A gene regulatory motif that generates oscillatory or multiway switch outputs

A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube

A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube.

A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube

A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range.

A shared transcriptional code orchestrates temporal patterning of the central nervous system

A theoretical framework for the regulation of Shh morphogen-controlled gene expression

ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis

Agonizing Hedgehog

An amphioxus Gli gene reveals conservation of midline patterning and the evolution of hedgehog signalling diversity in chordates

An inducible transgene expression system for zebrafish and chick

An interview with Olivier Pourquie

An intuitive graphical visualization technique for the interrogation of transcriptome data

An ode to the Node: 10 years in the life of a community blog

Anterior Hox genes interact with components of the neural crest specification network to induce neural crest fates

Applying an adaptive watershed to the tissue cell quantification during T-cell migration and embryonic development.

Canonical BMP7 activity is required for the generation of discrete neuronal populations in the dorsal spinal cord

Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways

Coordination of progenitor specification and growth in mouse and chick spinal cord

Decoding of position in the developing neural tube from antiparallel morphogen gradients.

Developing new associations

Development-on-chip: in vitro neural tube patterning with a microfluidic device

Developmental Pattern Formation in Phases.

Developmental pattern formation: insights from physics and biology

Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube

Distinct regulatory mechanisms act to establish and maintain Pax3 expression in the developing neural tube

Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity

Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog

ERK1/2 signalling dynamics promote neural differentiation by regulating the polycomb repressive complex

Epithelial organisation revealed by a network of cellular contacts

Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedback

Establishing neuronal circuitry: Hox genes make the connection.

Establishing neuronal diversity in the spinal cord: a time and a place

Floor Plate Patterning of Ventral Cell Types: Ventral Patterning

Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development

Foxj1 regulates floor plate cilia architecture and modifies the response of cells to sonic hedgehog signalling

G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.

Gene expression dysregulation domains are not a specific feature of Down syndrome

Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube

Generation of mice with functional inactivation of talpid3, a gene first identified in chicken

Genetics of system biology

Gli proteins and the control of spinal-cord patterning

Hedgehog signaling: from the Drosophila cuticle to anti-cancer drugs.

Hedgehog signaling: measuring ligand concentrations with receptor ratios

Hedgehog threads to spread

Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling

Homozygous Ft embryos are affected in floor plate maintenance and ventral neural tube patterning.

Human axial progenitors generate trunk neural crest cells in vitro

In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity

Inclusion and diversity in developmental biology: introducing the Node Network

Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung's disease in Bardet-Biedl syndrome

Inhibitory Gli3 activity negatively regulates Wnt/beta-catenin signaling

Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain

Integration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversity

Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism

Intrinsic Noise Profoundly Alters the Dynamics and Steady State of Morphogen-Controlled Bistable Genetic Switches ⬇️

JAKs and STATs branch out.

JAKs, STATs and signal transduction in response to the interferons and other cytokines

Jagged2 controls the generation of motor neuron and oligodendrocyte progenitors in the ventral spinal cord.

Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state

Let there be preLights: one year on

Limbs made to measure

Local retinoic acid signaling directs emergence of the extraocular muscle functional unit

Looking at neurodevelopment through a big data lens

Making a grade: Sonic Hedgehog signalling and the control of neural cell fate

Mathematical models help explain experimental data. Response to 'Transcriptional interpretation of Shh morphogen signaling: computational modeling validates empirically established models'.

Memory functions reveal structural properties of gene regulatory networks.

Morphogen interpretation: concentration, time, competence, and signaling dynamics

Morphogen interpretation: the transcriptional logic of neural tube patterning

Morphogen rules: design principles of gradient-mediated embryo patterning

Morphogens, modeling and patterning the neural tube: an interview with James Briscoe

Mouse mutagenesis identifies novel roles for left-right patterning genes in pulmonary, craniofacial, ocular, and limb development

Neural Progenitors Adopt Specific Identities by Directly Repressing All Alternative Progenitor Transcriptional Programs

Neural crest development is regulated by the transcription factor Sox9.

Neuronal differentiation affects tissue mechanics and progenitor arrangement in the vertebrate neuroepithelium