Lista de obras - Samuel Silvestre - Dominio Público Uruguay

3,3′-Diamino-N-methyldipropylamine as a versatile affinity ligand

artículo científico publicado en 2015

5-Hydrazinylethylidenepyrimidines effective against multidrug-resistant Acinetobacter baumannii: Synthesis and in vitro biological evaluation of antibacterial, radical scavenging and cytotoxic activities

scientific article published on 21 June 2019

Anticancer steroids: linking natural and semi-synthetic compounds ⬇️

artículo científico publicado el 1 de febrero de 2013

Bismuth compounds in medicinal chemistry.

artículo científico publicado en 2012

Bismuth(III) reagents in steroid and terpene chemistry.

artículo científico publicado en 2011

Cell proliferation effects of calix[4]arene derivatives

Considerations and Pitfalls in Selecting the Drug Vehicles for Evaluation of New Drug Candidates: Focus on in vivo Pharmaco-Toxicological Assays Based on the Rotarod Performance Test

artículo científico publicado en 2018

Dehydroepiandrosterone and 7-oxo-dehydroepiandrosterone in male reproductive health: Implications of differential regulation of human Sertoli cells metabolic profile

artículo científico publicado en 2015

Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology.

artículo científico publicado en 2016

Early preclinical evaluation of dihydropyrimidin(thi)ones as potential anticonvulsant drug candidates

artículo científico publicado en 2017

Effects of Hypericum perforatum extract and its main bioactive compounds on the cytotoxicity and expression of CYP1A2 and CYP2D6 in hepatic cells

artículo científico publicado en 2015

Effects of Hypericum perforatum hydroalcoholic extract, hypericin, and hyperforin on cytotoxicity and CYP3A4 mRNA expression in hepatic cell lines: a comparative study

From Xanthine Oxidase Inhibition to In Vivo Hypouricemic Effect: An Integrated Overview of In Vitro and In Vivo Studies with Focus on Natural Molecules and Analogues

scientific article published on 25 February 2020

Gastrodia elata and epilepsy: Rationale and therapeutic potential

artículo científico publicado en 2016

HepaRG cell line as an in vitro model for screening drug-drug interactions mediated by metabolic induction: amiodarone used as a model substance

artículo científico publicado en 2014

Natural Products as a Source for New Leads in Gout Treatment

artículo científico publicado en 2020

New applications for bismuth(III) salts in organic synthesis: from bulk chemicals to steroid and terpene chemistry

artículo científico publicado en 2012

Novel 4-acetamide-2-alkylthio-N-acetanilides resembling nimesulide: Synthesis, cell viability evaluation and in silico studies

artículo científico publicado en 2017

Nucleophilic Substitution of Hydrogen Facilitated by Quinone Methide Moieties in Benzo[cd]azulen-3-ones

artículo científico publicado en 2017

Oleanane-, ursane-, and quinone methide friedelane-type triterpenoid derivatives: Recent advances in cancer treatment

artículo científico publicado en 2017

Potential antitumoral 3,4-dihydropyrimidin-2-(1H)-ones: synthesis, in vitro biological evaluation and QSAR studies

scholarly article in RSC Advances, vol. 6 no. 88, 2016

Recent Developments in New Therapeutic Agents against Alzheimer and Parkinson Diseases: In-Silico Approaches

artículo científico publicado en 2021

Recent Highlights on Molecular Hybrids Potentially Useful in Central Nervous System Disorders

artículo científico publicado en 2016

Screening of pharmacokinetic properties of fifty dihydropyrimidin(thi)one derivatives using a combo of in vitro and in silico assays

artículo científico

Simultaneous Quantification of Antidepressants and Metabolites in Urine and Plasma Samples by GC–MS for Therapeutic Drug Monitoring

Sodium Tripolyphosphate: an excipient with intrinsic in vitro anti-Candida activity

artículo científico publicado en 2011

Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases.

artículo científico

Steroidal oximes: useful compounds with antitumor activities

artículo científico publicado en 2017

Synthesis and process optimization of symmetric and unsymmetric barbiturates C5-coupled with 2,1-benzisoxazoles

scientific article published on 14 March 2019

Synthesis, in vitro evaluation and QSAR modelling of potential antitumoral 3,4-dihydropyrimidin-2-(1H)-thiones

Targeting of mitochondria-endoplasmic reticulum by fluorescent macrocyclic compounds.

artículo científico publicado en 2011

Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative agents.

artículo científico publicado en 2017

Lista de obras de Samuel Silvestre

3,3′-Diamino-N-methyldipropylamine as a versatile affinity ligand

5-Hydrazinylethylidenepyrimidines effective against multidrug-resistant Acinetobacter baumannii: Synthesis and in vitro biological evaluation of antibacterial, radical scavenging and cytotoxic activities

Anticancer steroids: linking natural and semi-synthetic compounds ⬇️

Bismuth compounds in medicinal chemistry.

Bismuth(III) reagents in steroid and terpene chemistry.

Cell proliferation effects of calix[4]arene derivatives

Considerations and Pitfalls in Selecting the Drug Vehicles for Evaluation of New Drug Candidates: Focus on in vivo Pharmaco-Toxicological Assays Based on the Rotarod Performance Test

Dehydroepiandrosterone and 7-oxo-dehydroepiandrosterone in male reproductive health: Implications of differential regulation of human Sertoli cells metabolic profile

Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology.

Early preclinical evaluation of dihydropyrimidin(thi)ones as potential anticonvulsant drug candidates

Effects of Hypericum perforatum extract and its main bioactive compounds on the cytotoxicity and expression of CYP1A2 and CYP2D6 in hepatic cells

Effects of Hypericum perforatum hydroalcoholic extract, hypericin, and hyperforin on cytotoxicity and CYP3A4 mRNA expression in hepatic cell lines: a comparative study

From Xanthine Oxidase Inhibition to In Vivo Hypouricemic Effect: An Integrated Overview of In Vitro and In Vivo Studies with Focus on Natural Molecules and Analogues

Gastrodia elata and epilepsy: Rationale and therapeutic potential

HepaRG cell line as an in vitro model for screening drug-drug interactions mediated by metabolic induction: amiodarone used as a model substance

Natural Products as a Source for New Leads in Gout Treatment

New applications for bismuth(III) salts in organic synthesis: from bulk chemicals to steroid and terpene chemistry

Novel 4-acetamide-2-alkylthio-N-acetanilides resembling nimesulide: Synthesis, cell viability evaluation and in silico studies

Nucleophilic Substitution of Hydrogen Facilitated by Quinone Methide Moieties in Benzo[cd]azulen-3-ones

Oleanane-, ursane-, and quinone methide friedelane-type triterpenoid derivatives: Recent advances in cancer treatment

Potential antitumoral 3,4-dihydropyrimidin-2-(1H)-ones: synthesis, in vitro biological evaluation and QSAR studies

Recent Developments in New Therapeutic Agents against Alzheimer and Parkinson Diseases: In-Silico Approaches

Recent Highlights on Molecular Hybrids Potentially Useful in Central Nervous System Disorders

Screening of pharmacokinetic properties of fifty dihydropyrimidin(thi)one derivatives using a combo of in vitro and in silico assays

Simultaneous Quantification of Antidepressants and Metabolites in Urine and Plasma Samples by GC–MS for Therapeutic Drug Monitoring

Sodium Tripolyphosphate: an excipient with intrinsic in vitro anti-Candida activity

Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases.

Steroidal oximes: useful compounds with antitumor activities

Synthesis and process optimization of symmetric and unsymmetric barbiturates C5-coupled with 2,1-benzisoxazoles

Synthesis, in vitro evaluation and QSAR modelling of potential antitumoral 3,4-dihydropyrimidin-2-(1H)-thiones

Targeting of mitochondria-endoplasmic reticulum by fluorescent macrocyclic compounds.

Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative agents.