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Lista de obras de Rami A Al-Horani

A small group of sulfated benzofurans induces steady-state submaximal inhibition of thrombin

artículo científico publicado en 2018

A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding

scientific article published on 10 September 2019

Allosteric Inhibition of Factor XIIIa. Non-Saccharide Glycosaminoglycan Mimetics, but Not Glycosaminoglycans, Exhibit Promising Inhibition Profile.

artículo científico publicado en 2016

Allosteric Partial Inhibition of Monomeric Proteases. Sulfated Coumarins Induce Regulation, not just Inhibition, of Thrombin.

artículo científico publicado en 2016

Allosteric inhibition of factor XIa. Sulfated non-saccharide glycosaminoglycan mimetics as promising anticoagulants

artículo científico publicado en 2015

Chemical sulfation of small molecules—advances and challenges

artículo científico publicado el 17 de abril de 2010

Designing allosteric inhibitors of factor XIa. Lessons from the interactions of sulfated pentagalloylglucopyranosides

artículo científico publicado en 2014

Designing nonsaccharide, allosteric activators of antithrombin for accelerated inhibition of factor Xa.

artículo científico publicado en 2011

Discovery of Allosteric Modulators of Factor XIa by Targeting Hydrophobic Domains Adjacent to Its Heparin-Binding Site

artículo científico publicado el 18 de marzo de 2013

Discovery of Benzyl Tetraphosphonate Derivative as Inhibitor of Human Factor Xia

artículo científico publicado en 2020

Discovery of Chromen-7-yl Furan-2-Carboxylate as a Potent and Selective Factor XIa Inhibitor

artículo científico publicado en 2017

Electronically Rich N-Substituted Tetrahydroisoquinoline 3-Carboxylic Acid Esters: Concise Synthesis and Conformational Studies

artículo científico publicado en 2012

Factor XI(a) inhibitors for thrombosis: an updated patent review (2016-present)

scientific article published on 19 December 2019

Factor XIa inhibitors: A review of the patent literature

artículo científico publicado en 2016

Glycosaminoglycan-protein interaction studies using fluorescence spectroscopy.

artículo científico publicado en 2015

Inhibition of Herpes Simplex Virus-1 Entry into Human Cells by Nonsaccharide Glycosaminoglycan Mimetics

artículo científico publicado en 2018

New Small Molecule Drugs for Thrombocytopenia: Chemical, Pharmacological, and Therapeutic Use Considerations

scientific article published on 20 June 2019

Plasmin regulation through allosteric, sulfated, small molecules.

artículo científico publicado en 2015

Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffold.

artículo científico publicado en 2012

Potent, Selective, Allosteric Inhibition of Human Plasmin by Sulfated Non-Saccharide Glycosaminoglycan Mimetics.

artículo científico publicado en 2016

Potential Anti-COVID-19 Therapeutics that Block the Early Stage of the Viral Life Cycle: Structures, Mechanisms, and Clinical Trials

artículo científico publicado en 2020

Potential Anti-SARS-CoV-2 Therapeutics That Target the Post-Entry Stages of the Viral Life Cycle: A Comprehensive Review

artículo científico publicado en 2020

Potential Therapeutic Roles for Direct Factor Xa Inhibitors in Coronavirus Infections

scientific article published on 12 September 2020

Recent advances in the discovery and development of factor XI/XIa inhibitors

artículo científico publicado en 2018

Recent advances on plasmin inhibitors for the treatment of fibrinolysis-related disorders

artículo científico

Serpin regulation of fibrinolytic system: implications for therapeutic applications in cardiovascular diseases

artículo científico publicado en 2014

Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa

artículo científico publicado en 2013

Synthesis of glycosaminoglycan mimetics through sulfation of polyphenols

artículo científico publicado en 2015

Synthetic, non-saccharide, glycosaminoglycan mimetics selectively target colon cancer stem cells.

artículo científico publicado en 2014

Targeting factor XI(a) for anticoagulation therapy: a patent landscape

artículo científico publicado en 2020

The In Vitro Effects of Pentamidine Isethionate on Coagulation and Fibrinolysis

scientific article published on 06 June 2019

Thrombin Inhibition by Argatroban: Potential Therapeutic Benefits in COVID-19

scientific article published on 01 September 2020