Lista de obras - Jette S Kastrup - Dominio Público Uruguay

(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements, Structural and Biological Investigation

artículo científico publicado en 2018

7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency

artículo científico publicado en 2017

A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study

artículo científico publicado en 2005

A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils

artículo científico publicado en 2007

A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

artículo científico publicado en 2012

A new phenylalanine derivative acts as an antagonist at the AMPA receptor GluA2 and introduces partial domain closure: synthesis, resolution, pharmacology, and crystal structure

artículo científico publicado en 2011

A novel dualistic profile of an allosteric AMPA receptor modulator identified through studies on recombinant receptors, mouse hippocampal synapses and crystal structures.

artículo científico publicado en 2015

A parallel panning scheme used for selection of a GluA4-specific Fab targeting the ligand-binding domain

artículo científico publicado en 2016

A pharmacological profile of the high-affinity GluK5 kainate receptor.

artículo científico publicado en 2016

A tetrazolyl-substituted subtype-selective AMPA receptor agonist

artículo científico publicado en 2007

A unique set of SH3-SH3 interactions controls IB1 homodimerization

artículo científico publicado en 2006

Acetylcholine-Binding Protein Engineered to Mimic the α4-α4 Binding Pocket in α4β2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity

artículo científico publicado en 2015

Atomic resolution structure of human HBP/CAP37/azurocidin

artículo científico publicado en 1998

Binding mode of an α-amino acid-linked quinoxaline-2,3-dione analogue at glutamate receptor subtype GluK1

artículo científico publicado en 2015

Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2

artículo científico publicado en 2020

Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate

artículo científico publicado en 2011

Biostructural and pharmacological studies of bicyclic analogues of the 3-isoxazolol glutamate receptor agonist ibotenic acid

artículo científico publicado en 2010

Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters

artículo científico publicado en 2013

Crystal Structure and Pharmacological Characterization of a Novel N-Methyl-D-aspartate (NMDA) Receptor Antagonist at the GluN1 Glycine Binding Site

artículo científico publicado en 2013

Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHβE Suggests a Unique Mode of Antagonism

artículo científico publicado en 2012

Crystal Structure of a Partly Self-Complementary Peptide Nucleic Acid (PNA) Oligomer Showing a Duplex−Triplex Network†

artículo científico publicado en 2005

Crystal Structures of Potent Dimeric Positive Allosteric Modulators at the Ligand-Binding Domain of the GluA2 Receptor

artículo científico publicado en 2018

Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis

artículo científico publicado en 2004

Crystal structure of tetranectin, a trimeric plasminogen‐binding protein with an α‐helical coiled coil ⬇️

artículo científico publicado el 28 de julio de 1997

Crystal structure of the Ig1 domain of the neural cell adhesion molecule NCAM2 displays domain swapping

artículo científico publicado en 2008

Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate

artículo científico publicado en 2005

Crystal structures of two peptide–HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype

artículo científico publicado en 2006

Crystallization and molecular-replacement solution of a truncated form of human recombinant tetranectin

artículo científico publicado en 2000

Crystallization and preliminary X-ray analysis of a PNA-DNA complex

artículo científico publicado en 1995

Design and Synthesis of a Series of l-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1

artículo científico publicado en 2016

Dimerization effect of sucrose octasulfate on rat FGF1

artículo científico publicado en 2008

Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2

artículo científico publicado en 2009

Engineered α4β2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4-α4 interface.

artículo científico publicado en 2015

Enhancing Action of Positive Allosteric Modulators through the Design of Dimeric Compounds

artículo científico publicado en 2018

Enthalpy-Entropy Compensation in the Binding of Modulators at Ionotropic Glutamate Receptor GluA2.

artículo científico publicado en 2016

Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases

article published in 2011

Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP.

artículo científico publicado en 2005

Expression, crystallization and preliminary X-ray analysis of extracellular modules of the neural cell-adhesion molecules NCAM and L1.

artículo científico publicado en 2004

Expression, crystallization and preliminary X-ray analysis of the extracellular Ig modules I-IV and F3 modules I-III of the neural cell-adhesion molecule L1

artículo científico publicado en 2005

Full Domain Closure of the Ligand-binding Core of the Ionotropic Glutamate Receptor iGluR5 Induced by the High Affinity Agonist Dysiherbaine and the Functional Antagonist 8,9-Dideoxyneodysiherbaine

artículo científico publicado en 2009

GluR2 ligand-binding core complexes: importance of the isoxazolol moiety and 5-substituent for the binding mode of AMPA-type agonists

artículo científico publicado en 2002

High resolution crystal structures of the p120 RasGAP SH3 domain

artículo científico publicado en 2007

High-resolution structure of HLA-A*1101 in complex with SARS nucleocapsid peptide

artículo científico publicado en 2005

Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate Receptors

artículo científico publicado en 2017

Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy

artículo científico publicado en 2013

Intersubunit Bridge Formation Governs Agonist Efficacy at Nicotinic Acetylcholine 4 2 Receptors: UNIQUE ROLE OF HALOGEN BONDING REVEALED

artículo científico publicado en 2012

Invisible detergents for structure determination of membrane proteins by small-angle neutron scattering.

artículo científico publicado en 2017

Ionotropic glutamate-like receptor 2 binds D-serine and glycine

artículo científico publicado en 2007

Kainate induces various domain closures in AMPA and kainate receptors

artículo científico publicado en 2012

L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain

artículo científico publicado en 2014

Lessons from crystal structures of kainate receptors

artículo científico publicado en 2016

Ligand binding analyses of the putative peptide transporter YjdL from E. coli display a significant selectivity towards dipeptides.

artículo científico publicado en 2009

Lipopolysaccharide affinity measurement by scintillation proximity assay: application to human heparin binding protein

artículo científico publicado en 2000

Measurement of apoptosis by the TUNEL method using scintillating microplates.

artículo científico publicado en 2000

Modulation of the dimer interface at ionotropic glutamate-like receptor delta2 by D-serine and extracellular calcium

artículo científico publicado en 2009

Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors

artículo científico publicado en 2012

Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4

artículo científico publicado en 2008

Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors

artículo científico publicado en 2014

Molecular recognition of two 2,4-syn-functionalized (S)-glutamate analogues by the kainate receptor GluK3 ligand binding domain

artículo científico publicado en 2014

N-(7-(1H-Imidazol-1-yl)-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)benzamide, a New Kainate Receptor Selective Antagonist and Analgesic: Synthesis, X-ray Crystallography, Structure-Affinity Relationships, and in Vitro and in Vivo P

scientific article published on 31 October 2019

N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships, and in Vitro Pharmacology

scientific article published on 23 January 2019

Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor

artículo científico publicado en 2010

Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus

artículo científico publicado en 2010

Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid

artículo científico publicado en 2007

Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors

artículo científico publicado en 2012

Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors

artículo científico publicado en 2015

Recovery from desensitization in GluA2 AMPA receptors is affected by a single mutation in the N-terminal domain interface

artículo científico publicado en 2024

Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis.

artículo científico publicado en 2004

Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization

artículo científico publicado en 2011

Small angle X-ray studies reveal that Aspergillus niger glucoamylase has a defined extended conformation and can form dimers in solution

artículo científico publicado en 2008

Structural Studies of Nicotinic Acetylcholine Receptors: Using Acetylcholine-Binding Protein as a Structural Surrogate.

artículo científico publicado en 2015

Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors

artículo científico publicado en 2014

Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors

artículo científico publicado en 2012

Structural basis of cell-cell adhesion by NCAM

artículo científico publicado en 2000

Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family

artículo científico publicado en 2004

Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule

artículo científico publicado en 2011

Structural rearrangements of sucrose phosphorylase from Bifidobacterium adolescentis during sucrose conversion.

artículo científico

Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.

artículo científico publicado en 2017

Structure and Interactions of NCAM Ig1-2-3 Suggest a Novel Zipper Mechanism for Homophilic Adhesion ⬇️

artículo científico publicado el 1 de octubre de 2003

Structure and function of the N-linked glycans of HBP/CAP37/azurocidin: crystal structure determination and biological characterization of nonglycosylated HBP.

artículo científico publicado en 1999

Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue.

artículo científico publicado en 2006

Structure of a SARS coronavirus-derived peptide bound to the human major histocompatibility complex class I molecule HLA-B*1501

artículo científico publicado en 2008

Structure of rat acidic fibroblast growth factor at 1.4 Å resolution

artículo científico publicado en 2007

Structure of recombinant Ves v 2 at 2.0 Angstrom resolution: structural analysis of an allergenic hyaluronidase from wasp venom.

artículo científico publicado en 2006

Structure of the C-Type Lectin Carbohydrate Recognition Domain of Human Tetranectin ⬇️

artículo científico publicado el 1 de septiembre de 1998

Structure of the first PDZ domain of human PSD-93

artículo científico publicado en 2009

Structure of the house dust mite allergen Der f 2: implications for function and molecular basis of IgE cross-reactivity

artículo científico publicado en 2005

Structure-Activity Relationship Study of Ionotropic Glutamate Receptor Antagonist (2S,3R)-3-(3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid

artículo científico publicado en 2015

Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency

artículo científico publicado en 2008

Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

artículo científico publicado en 2012

Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors

artículo científico publicado en 2016

Studies on an ( S )-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic Acid (AMPA) Receptor Antagonist IKM-159: Asymmetric Synthesis, Neuroactivity, and Structural Characterization

artículo científico publicado en 2013

Synthesis and Pharmacology of Mono-, Di-, and Trialkyl-Substituted 7-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides Combined with X-ray Structure Analysis to Understand the Unexpected Structure-Activity Relationship at AMPA Receptors

artículo científico publicado en 2016

Synthesis, pharmacological and structural characterization, and thermodynamic aspects of GluA2-positive allosteric modulators with a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide scaffold

artículo científico publicado en 2013

Synthesis, pharmacology, and biostructural characterization of novel α4β2 nicotinic acetylcholine receptor agonists

artículo científico publicado en 2013

The SAXS solution structure of RF1 differs from its crystal structure and is similar to its ribosome bound cryo-EM structure

artículo científico publicado en 2005

The Structure of a High-Affinity Kainate Receptor: GluK4 Ligand-Binding Domain Crystallized with Kainate

artículo científico publicado en 2016

The apo structure of sucrose hydrolase from Xanthomonas campestris pv. campestris shows an open active-site groove

artículo científico publicado en 2009

The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization

artículo científico publicado en 2009

The influence of a chiral amino acid on the helical handedness of PNA in solution and in crystals

artículo científico publicado en 2004

The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region.

artículo científico publicado en 2017

The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209.

artículo científico publicado en 2006

The structure of the complex between a branched pentasaccharide and Thermobacillus xylanilyticus GH-51 arabinofuranosidase reveals xylan-binding determinants and induced fit

artículo científico publicado en 2008

The structure of the mite allergen Blo t 1 explains the limited antibody cross-reactivity to Der p 1.

artículo científico publicado en 2016

Thermodynamic characterization of new positive allosteric modulators binding to the glutamate receptor A2 ligand-binding domain: combining experimental and computational methods unravels differences in driving forces

artículo científico publicado en 2014

Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2

artículo científico publicado en 2012

Tweaking Subtype Selectivity and Agonist Efficacy at (S)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) Receptors in a Small Series of BnTetAMPA Analogues

artículo científico publicado en 2016

Two distinct allosteric binding sites at α4β2 nicotinic acetylcholine receptors revealed by NS206 and NS9283 give unique insights to binding activity-associated linkage at Cys-loop receptors.

artículo científico publicado en 2013

Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2.

artículo científico publicado en 2004

Use of the 4-Hydroxytriazole Moiety as a Bioisosteric Tool in the Development of Ionotropic Glutamate Receptor Ligands

scientific article published on 18 April 2019

Water-molecule network and active-site flexibility of apo protein tyrosine phosphatase 1B.

artículo científico publicado en 2004

X-ray structure of the 154-amino-acid form of recombinant human basic fibroblast growth factor. comparison with the truncated 146-amino-acid form.

artículo científico publicado en 1997

Lista de obras de Jette S Kastrup

(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements, Structural and Biological Investigation

7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency

A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study

A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils

A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

A new phenylalanine derivative acts as an antagonist at the AMPA receptor GluA2 and introduces partial domain closure: synthesis, resolution, pharmacology, and crystal structure

A novel dualistic profile of an allosteric AMPA receptor modulator identified through studies on recombinant receptors, mouse hippocampal synapses and crystal structures.

A parallel panning scheme used for selection of a GluA4-specific Fab targeting the ligand-binding domain

A pharmacological profile of the high-affinity GluK5 kainate receptor.

A tetrazolyl-substituted subtype-selective AMPA receptor agonist

A unique set of SH3-SH3 interactions controls IB1 homodimerization

Acetylcholine-Binding Protein Engineered to Mimic the α4-α4 Binding Pocket in α4β2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity

Atomic resolution structure of human HBP/CAP37/azurocidin

Binding mode of an α-amino acid-linked quinoxaline-2,3-dione analogue at glutamate receptor subtype GluK1

Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2

Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate

Biostructural and pharmacological studies of bicyclic analogues of the 3-isoxazolol glutamate receptor agonist ibotenic acid

Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters

Crystal Structure and Pharmacological Characterization of a Novel N-Methyl-D-aspartate (NMDA) Receptor Antagonist at the GluN1 Glycine Binding Site

Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHβE Suggests a Unique Mode of Antagonism

Crystal Structure of a Partly Self-Complementary Peptide Nucleic Acid (PNA) Oligomer Showing a Duplex−Triplex Network†

Crystal Structures of Potent Dimeric Positive Allosteric Modulators at the Ligand-Binding Domain of the GluA2 Receptor

Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis

Crystal structure of tetranectin, a trimeric plasminogen‐binding protein with an α‐helical coiled coil ⬇️

Crystal structure of the Ig1 domain of the neural cell adhesion molecule NCAM2 displays domain swapping

Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate

Crystal structures of two peptide–HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype

Crystallization and molecular-replacement solution of a truncated form of human recombinant tetranectin

Crystallization and preliminary X-ray analysis of a PNA-DNA complex

Design and Synthesis of a Series of l-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1

Dimerization effect of sucrose octasulfate on rat FGF1

Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2

Engineered α4β2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4-α4 interface.

Enhancing Action of Positive Allosteric Modulators through the Design of Dimeric Compounds

Enthalpy-Entropy Compensation in the Binding of Modulators at Ionotropic Glutamate Receptor GluA2.

Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases

Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP.

Expression, crystallization and preliminary X-ray analysis of extracellular modules of the neural cell-adhesion molecules NCAM and L1.

Expression, crystallization and preliminary X-ray analysis of the extracellular Ig modules I-IV and F3 modules I-III of the neural cell-adhesion molecule L1

Full Domain Closure of the Ligand-binding Core of the Ionotropic Glutamate Receptor iGluR5 Induced by the High Affinity Agonist Dysiherbaine and the Functional Antagonist 8,9-Dideoxyneodysiherbaine

GluR2 ligand-binding core complexes: importance of the isoxazolol moiety and 5-substituent for the binding mode of AMPA-type agonists

High resolution crystal structures of the p120 RasGAP SH3 domain

High-resolution structure of HLA-A*1101 in complex with SARS nucleocapsid peptide

Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate Receptors

Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy

Intersubunit Bridge Formation Governs Agonist Efficacy at Nicotinic Acetylcholine 4 2 Receptors: UNIQUE ROLE OF HALOGEN BONDING REVEALED

Invisible detergents for structure determination of membrane proteins by small-angle neutron scattering.

Ionotropic glutamate-like receptor 2 binds D-serine and glycine

Kainate induces various domain closures in AMPA and kainate receptors

L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain

Lessons from crystal structures of kainate receptors

Ligand binding analyses of the putative peptide transporter YjdL from E. coli display a significant selectivity towards dipeptides.

Lipopolysaccharide affinity measurement by scintillation proximity assay: application to human heparin binding protein

Measurement of apoptosis by the TUNEL method using scintillating microplates.

Modulation of the dimer interface at ionotropic glutamate-like receptor delta2 by D-serine and extracellular calcium

Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors

Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4

Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors

Molecular recognition of two 2,4-syn-functionalized (S)-glutamate analogues by the kainate receptor GluK3 ligand binding domain

N-(7-(1H-Imidazol-1-yl)-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)benzamide, a New Kainate Receptor Selective Antagonist and Analgesic: Synthesis, X-ray Crystallography, Structure-Affinity Relationships, and in Vitro and in Vivo P

N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships, and in Vitro Pharmacology

Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor

Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus

Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid

Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors

Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors

Recovery from desensitization in GluA2 AMPA receptors is affected by a single mutation in the N-terminal domain interface

Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis.

Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization

Small angle X-ray studies reveal that Aspergillus niger glucoamylase has a defined extended conformation and can form dimers in solution

Structural Studies of Nicotinic Acetylcholine Receptors: Using Acetylcholine-Binding Protein as a Structural Surrogate.

Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors

Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors

Structural basis of cell-cell adhesion by NCAM

Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family

Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule

Structural rearrangements of sucrose phosphorylase from Bifidobacterium adolescentis during sucrose conversion.

Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.

Structure and Interactions of NCAM Ig1-2-3 Suggest a Novel Zipper Mechanism for Homophilic Adhesion ⬇️