Lista de obras - Patrizia Lavia - Dominio Público Uruguay

A role for endogenous reverse transcriptase in tumorigenesis and as a target in differentiating cancer therapy.

artículo científico publicado en 2006

A role of p73 in mitotic exit.

artículo científico publicado en 2005

Activation of human ribosomal genes by 5-azacytidine

article

Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity.

artículo científico publicado en 2008

Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forces

artículo científico publicado en 2011

Clonal inheritance of rRNA gene activity: Cytological evidence in human cells

article

Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epithelium

artículo científico publicado en 2000

Control of Aurora-A stability through interaction with TPX2.

artículo científico publicado en 2010

Cytosine methylation transforms an E2F site in the retinoblastoma gene promoter into a binding site for the general repressor methylcytosine-binding protein 2 (MeCP2).

artículo científico publicado en 1999

Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.

artículo científico publicado en 2011

Different effects of histone H1 on de novo DNA methylation in vitro depend on both the DNA base composition and the DNA methyltransferase.

artículo científico publicado en 1996

Effect of 5-azacytidine (5-azaC) on the induction of chromatid aberrations (CA) and sister-chromatid exchanges (SCE)

artículo científico publicado en 1985

Identification of small molecule inhibitors of the Aurora-A/TPX2 complex

artículo científico publicado en 2017

Importin-β and CRM1 control a RANBP2 spatiotemporal switch essential for mitotic kinetochore function.

artículo científico publicado en 2017

Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores.

artículo científico publicado en 2012

Importin-β/karyopherin-β1 modulates mitotic microtubule function and taxane sensitivity in cancer cells via its nucleoporin-binding region

scientific article published on 06 September 2019

Interactions with Single-stranded and Double-stranded DNA-binding Factors and Alternative Promoter Conformation upon Transcriptional Activation of the Htf9-a/RanBP1 and Htf9-c Genes ⬇️

artículo científico publicado el 2 de enero de 1998

Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cells

artículo científico publicado en 2008

Mammalian RanBP1 regulates centrosome cohesion during mitosis

artículo científico publicado en 2003

Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules

artículo científico publicado en 2017

Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors

artículo científico publicado en 2011

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer

artículo científico publicado en 2015

New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer

artículo científico publicado en 2014

Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity.

artículo científico publicado en 2003

Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy

artículo científico publicado en 2015

RANBP1 localizes a subset of mitotic regulatory factors on spindle microtubules and regulates chromosome segregation in human cells.

artículo científico publicado en 2007

Ran control of mitosis in human cells: gradients and local signals

artículo científico publicado en 2010

Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high-risk neuroblastoma

article

Subcellular localization of the five members of the human steroid 5α-reductase family

artículo científico publicado en 2017

Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.

artículo científico publicado en 2016

The GTPase RAN regulates multiple steps of the centrosome life cycle

artículo científico publicado en 2016

The GTPase Ran: regulation of cell life and potential roles in cell transformation.

artículo científico publicado en 2008

The Mitotic Apparatus and Kinetochores in Microcephaly and Neurodevelopmental Diseases

artículo científico publicado en 2019

Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors

artículo científico publicado en 2012

Two E2F sites control growth-regulated and cell cycle-regulated transcription of the Htf9-a/RanBP1 gene through functionally distinct mechanisms.

artículo científico publicado en 1999

Visualization of human karyopherin beta-1/importin beta-1 interactions with protein partners in mitotic cells by co-immunoprecipitation and proximity ligation assays

artículo científico publicado en 2018

p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells.

artículo científico publicado en 2016

p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle.

artículo científico publicado en 2001

p53 localization at centrosomes during mitosis and postmitotic checkpoint are ATM-dependent and require serine 15 phosphorylation.

artículo científico publicado en 2004

p53-independent apoptosis and p53-dependent block of DNA rereplication following mitotic spindle inhibition in human cells

artículo científico publicado en 1999

Lista de obras de Patrizia Lavia

A role for endogenous reverse transcriptase in tumorigenesis and as a target in differentiating cancer therapy.

A role of p73 in mitotic exit.

Activation of human ribosomal genes by 5-azacytidine

Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity.

Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forces

Clonal inheritance of rRNA gene activity: Cytological evidence in human cells

Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epithelium

Control of Aurora-A stability through interaction with TPX2.

Cytosine methylation transforms an E2F site in the retinoblastoma gene promoter into a binding site for the general repressor methylcytosine-binding protein 2 (MeCP2).

Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.

Different effects of histone H1 on de novo DNA methylation in vitro depend on both the DNA base composition and the DNA methyltransferase.

Effect of 5-azacytidine (5-azaC) on the induction of chromatid aberrations (CA) and sister-chromatid exchanges (SCE)

Identification of small molecule inhibitors of the Aurora-A/TPX2 complex

Importin-β and CRM1 control a RANBP2 spatiotemporal switch essential for mitotic kinetochore function.

Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores.

Importin-β/karyopherin-β1 modulates mitotic microtubule function and taxane sensitivity in cancer cells via its nucleoporin-binding region

Interactions with Single-stranded and Double-stranded DNA-binding Factors and Alternative Promoter Conformation upon Transcriptional Activation of the Htf9-a/RanBP1 and Htf9-c Genes ⬇️

Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cells

Mammalian RanBP1 regulates centrosome cohesion during mitosis

Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules

Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer

New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer

Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity.

Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy

RANBP1 localizes a subset of mitotic regulatory factors on spindle microtubules and regulates chromosome segregation in human cells.

Ran control of mitosis in human cells: gradients and local signals

Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high-risk neuroblastoma

Subcellular localization of the five members of the human steroid 5α-reductase family

Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.

The GTPase RAN regulates multiple steps of the centrosome life cycle

The GTPase Ran: regulation of cell life and potential roles in cell transformation.

The Mitotic Apparatus and Kinetochores in Microcephaly and Neurodevelopmental Diseases

Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors

Two E2F sites control growth-regulated and cell cycle-regulated transcription of the Htf9-a/RanBP1 gene through functionally distinct mechanisms.

Visualization of human karyopherin beta-1/importin beta-1 interactions with protein partners in mitotic cells by co-immunoprecipitation and proximity ligation assays

p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells.

p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle.

p53 localization at centrosomes during mitosis and postmitotic checkpoint are ATM-dependent and require serine 15 phosphorylation.

p53-independent apoptosis and p53-dependent block of DNA rereplication following mitotic spindle inhibition in human cells