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Lista de obras de Mitsunori Fukuda

A Novel Method for Visualizing Melanosome and Melanin Distribution in Human Skin Tissues

artículo científico publicado en 2020

A Varp-Binding Protein, RACK1, Regulates Dendrite Outgrowth through Stabilization of Varp Protein in Mouse Melanocytes

artículo científico publicado en 2016

A comprehensive analysis of Rab GTPases reveals a role for Rab34 in serum-starvation-induced primary ciliogenesis

scientific article published on 15 July 2020

A novel alternatively spliced variant of synaptotagmin VI lacking a transmembrane domain. Implications for distinct functions of the two isoforms

scientific journal article

A possible role of Atg8 homologs as a scaffold for signal transduction

artículo científico publicado en 2011

A unique spacer domain of synaptotagmin IV is essential for Golgi localization.

artículo científico publicado en 2001

AATYK1A phosphorylation by Cdk5 regulates the recycling endosome pathway.

artículo científico publicado en 2010

ALS2, the small GTPase Rab17-interacting protein, regulates maturation and sorting of Rab17-associated endosomes

artículo científico publicado en 2020

AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain

artículo científico publicado en 2005

Activation-Inactivation Cycling of Rab35 and ARF6 Is Required for Phagocytosis of Zymosan in RAW264 Macrophages

artículo científico publicado en 2015

Acute accumulation of free cholesterol induces the degradation of perilipin 2 and Rab18-dependent fusion of ER and lipid droplets in cultured human hepatocytes

artículo científico publicado en 2016

Adenovirus-mediated silencing of synaptotagmin 9 inhibits Ca2+-dependent insulin secretion in islets

scientific journal article

All members of the EPI64 subfamily of TBC/RabGAPs also have GAP activities towards Ras.

artículo científico publicado en 2012

Alternative splicing in the first alpha-helical region of the Rab-binding domain of Rim regulates Rab3A binding activity: is Rim a Rab3 effector protein during evolution?

artículo científico publicado en 2004

Amino acid residues before the hydrophobic region which are critical for membrane translocation of the N‐terminal domain of synaptotagmin II ⬇️

artículo científico publicado el 2 de noviembre de 2001

An ARF6/Rab35 GTPase cascade for endocytic recycling and successful cytokinesis

artículo científico publicado en 2012

An autophagy-dependent tubular lysosomal network synchronizes degradative activity required for muscle remodeling

scientific article published on 19 October 2020

An ultra-stable cytoplasmic antibody engineered for in vivo applications

scientific article published on 17 January 2020

Analysis of the role of Rab27 effector Slp4-a/Granuphilin-a in dense-core vesicle exocytosis

artículo científico publicado en 2005

Androgen Receptor Signaling Reduces the Efficacy of Bacillus Calmette-Guérin Therapy for Bladder Cancer via Modulating Rab27b-induced Exocytosis

artículo científico publicado en 2020

Anterograde transport of TrkB in axons is mediated by direct interaction with Slp1 and Rab27.

artículo científico publicado en 2009

Arf6, Rab11 and transferrin receptor define distinct populations of recycling endosomes.

artículo científico publicado en 2013

Assay and functional interactions of Rim2 with Rab3

artículo científico publicado en 2005

Assay of Rab17 and its guanine nucleotide exchange factor Rabex-5 in the dendrites of hippocampal neurons

artículo científico publicado en 2015

Assay of the Rab-binding specificity of rabphilin and Noc2: target molecules for Rab27

artículo científico publicado en 2005

Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity.

artículo científico publicado en 2012

Atg16L2, a novel isoform of mammalian Atg16L that is not essential for canonical autophagy despite forming an Atg12–5-16L2 complex ⬇️

artículo científico publicado el 1 de diciembre de 2011

Atmospheric scanning electron microscope system with an open sample chamber: configuration and applications

artículo científico publicado en 2014

Axolemmal repair requires proteins that mediate synaptic vesicle fusion

artículo científico publicado en 2000

BCA2/Rabring7 promotes tetherin-dependent HIV-1 restriction

artículo científico publicado en 2009

Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction

scientific journal article

C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia

artículo científico publicado en 2017

CD2-associated protein (CD2AP) overexpression accelerates amyloid precursor protein (APP) transfer from early endosomes to the lysosomal degradation pathway

artículo científico publicado en 2019

Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis

artículo científico publicado en 2002

Calcium-dependent and -independent hetero-oligomerization in the synaptotagmin family.

artículo científico publicado en 2000

Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B

scientific article published in Scientific Reports

Cdk5 Regulation of the GRAB-Mediated Rab8-Rab11 Cascade in Axon Outgrowth

artículo científico publicado en 2017

Characterization of a novel C. elegans RGS protein with a C2 domain: evidence for direct association between C2 domain and Galphaq subunit

artículo científico publicado en 2003

Characterization of the Pleckstrin Homology Domain of Btk as an Inositol Polyphosphate and Phosphoinositide Binding Domain ⬇️

artículo científico publicado el 18 de julio de 1997

Cholesterol controls lipid endocytosis through Rab11.

artículo científico publicado en 2007

Classical protein kinase C(s) regulates targeting of synaptotagmin IX to the endocytic recycling compartment.

artículo científico publicado en 2005

Comprehensive knockout analysis of the Rab family GTPases in epithelial cells

artículo científico publicado en 2019

Comprehensive screening for novel rab-binding proteins by GST pull-down assay using 60 different mammalian Rabs.

artículo científico publicado en 2010

Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X

scientific journal article

Constitutive GDP/GTP exchange and secretion-dependent GTP hydrolysis activity for Rab27 in platelets

artículo científico publicado en 2006

Cytoplasmic control of Rab family small GTPases through BAG6

artículo científico publicado en 2019

Dab1‐mediated colocalization of multi‐adaptor protein CIN85 with Reelin receptors, ApoER2 and VLDLR, in neurons ⬇️

artículo científico publicado el 19 de marzo de 2013

Decoding the regulation of mast cell exocytosis by networks of Rab GTPases

artículo científico publicado en 2012

Decreased basal mucus secretion by Slp2-a-deficient gastric surface mucous cells

scientific journal article

Dennd3 functions as a guanine nucleotide exchange factor for small GTPase Rab12 in mouse embryonic fibroblasts

artículo científico publicado en 2014

Differential distribution of synaptotagmin-1, -4, -7, and -9 in rat adrenal chromaffin cells.

artículo científico publicado en 2011

Differing susceptibility to autophagic degradation of two LC3-binding proteins: SQSTM1/p62 and TBC1D25/OATL1

artículo científico publicado en 2016

Dissociation of inositol polyphosphates from the C2B domain of synaptotagmin facilitates spontaneous release of catecholamines in adrenal chromaffin cells. A suggestive evidence of a fusion clamp by synaptotagmin

artículo científico publicado en 2011

Distinct Rab27A binding affinities of Slp2-a and Slac2-a/melanophilin: Hierarchy of Rab27A effectors

artículo científico publicado en 2006

Distinct roles of C2A and C2B domains of synaptotagmin in the regulation of exocytosis in adrenal chromaffin cells.

artículo científico publicado en 1997

Doc2gamma, a third isoform of double C2 protein, lacking calcium-dependent phospholipid binding activity

artículo científico publicado en 2000

Drosophila AD3 mutation of synaptotagmin impairs calcium-dependent self-oligomerization activity

artículo científico publicado en 2000

Dvl regulates endo- and exocytotic processes through binding to synaptotagmin

scientific article published on 01 January 2007

Dysferlin deficiency shows compensatory induction of Rab27A/Slp2a that may contribute to inflammatory onset.

artículo científico publicado en 2008

EPI64 Protein Functions as a Physiological GTPase-activating Protein for Rab27 Protein and Regulates Amylase Release in Rat Parotid Acinar Cells ⬇️

artículo científico publicado el 5 de agosto de 2011

Effect of forskolin on synaptotagmin IV protein trafficking in PC12 cells.

artículo científico publicado en 2004

Erratum to: drosophila AD3 mutation of synaptotagmin impairs calcium-dependent self-oligomerization activity (FEBS 24173)

artículo científico publicado en 2000

Essential role of RAB27A in determining constitutive human skin color ⬇️

artículo científico publicado el 23 de julio de 2012

Exclusion of synaptotagmin V at the phagocytic cup by Leishmania donovani lipophosphoglycan results in decreased promastigote internalization.

artículo científico publicado en 2011

Exome sequencing reveals a homozygous SYT14 mutation in adult-onset, autosomal-recessive spinocerebellar ataxia with psychomotor retardation

artículo científico publicado en 2011

Expression of Rab27B-binding protein Slp1 in pancreatic acinar cells and its involvement in amylase secretion

artículo científico publicado en 2008

Expression of synaptotagmin I or II promotes neurite outgrowth in PC12 cells

artículo científico publicado en 2000

Functional analysis of Rab27A and its effector Slp2-a in renal epithelial cells.

artículo científico publicado en 2015

Functional analysis of Slac2-c/MyRIP as a linker protein between melanosomes and myosin VIIa.

artículo científico publicado en 2005

Functional analysis of slac2-a/melanophilin as a linker protein between Rab27A and myosin Va in melanosome transport.

artículo científico

Functional diversity of C2 domains of synaptotagmin family. Mutational analysis of inositol high polyphosphate binding domain.

artículo científico publicado en 1995

Functional involvement of Noc2, a Rab27 effector, in rat parotid acinar cells

scientific journal article

Functional involvement of Rab1A in microtubule-dependent anterograde melanosome transport in melanocytes

scientific journal article

Functional involvement of synaptotagmin I/II C2A domain in neurite outgrowth of chick dorsal root ganglion neuron

artículo científico publicado en 1999

Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells.

artículo científico publicado en 2008

Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy

scientific article published on 07 January 2017

Genome-wide investigation of the Rab binding activity of RUN domains: development of a novel tool that specifically traps GTP-Rab35.

artículo científico publicado en 2011

Genomic structures of synaptotagmin II protein: comparison of exon-intron organization of the synaptotagmin gene family.

artículo científico publicado en 2000

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Identification and biochemical analysis of Slac2-c/MyRIP as a Rab27A-, myosin Va/VIIa-, and actin-binding protein

scientific article published on 01 January 2005

Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity

artículo científico publicado en 2009

Identification of EPI64 as a GTPase-activating protein specific for Rab27A

artículo científico publicado en 2006

Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling

artículo científico publicado en 2014

Imaging FITC-dextran as a Reporter for Regulated Exocytosis.

artículo científico publicado en 2018

Increased plasma membrane localization of O-glycosylation-deficient mutant of synaptotagmin I in PC12 cells

artículo científico publicado en 2008

Inhibition of endocytic vesicle fusion by Plk1-mediated phosphorylation of vimentin during mitosis

artículo científico publicado en 2013

Inositol 1,3,4,5-tetrakisphosphate binding activities of neuronal and non-neuronal synaptotagmins. Identification of conserved amino acid substitutions that abolish inositol 1,3,4,5-tetrakisphosphate binding to synaptotagmins III, V, and X.

artículo científico publicado en 1998

Inositol-1,3,4,5-tetrakisphosphate binding sites in control and ras-transformed NIH/3T3 fibroblasts.

artículo científico publicado en 1997

Intracellular trafficking of Clostridium perfringens iota-toxin b.

artículo científico publicado en 2012

Investigating mast cell secretory granules; from biosynthesis to exocytosis

artículo científico publicado en 2015

Involvement of the Rab27 binding protein Slac2c/MyRIP in insulin exocytosis

artículo científico publicado en 2003

JNK phosphorylates synaptotagmin-4 and enhances Ca2+-evoked release

scientific journal article

LMTK1 regulates dendritic formation by regulating movement of Rab11A-positive endosomes.

artículo científico publicado en 2014

LMTK1/AATYK1 is a novel regulator of axonal outgrowth that acts via Rab11 in a Cdk5-dependent manner

scientific journal article

LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis

article published in the Proceedings of the National Academy of Sciences of the United States of America

Leishmania promastigotes induce cytokine secretion in macrophages through the degradation of synaptotagmin XI

scientific journal article

Lys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein

artículo científico publicado en 2014

M-INK, a novel tool for visualizing melanosomes and melanocores.

artículo científico publicado en 2017

MADD/DENN/Rab3GEP functions as a guanine nucleotide exchange factor for Rab27 during granule exocytosis of rat parotid acinar cells ⬇️

artículo científico publicado el 20 de mayo de 2013

Measurement of Rab35 activity with the GTP-Rab35 trapper RBD35.

artículo científico publicado en 2015

Mechanism of the SDS-resistant synaptotagmin clustering mediated by the cysteine cluster at the interface between the transmembrane and spacer domains.

artículo científico publicado en 2001

Melanoregulin regulates retrograde melanosome transport through interaction with the RILP·p150Glued complex in melanocytes ⬇️

artículo científico publicado el 24 de enero de 2012

Methods of analysis of the membrane trafficking pathway from recycling endosomes to lysosomes

artículo científico publicado en 2014

Molecular cloning, expression, and characterization of a novel class of synaptotagmin (Syt XIV) conserved from Drosophila to humans

scientific journal article

Molecular mechanism of myosin Va recruitment to dense core secretory granules

artículo científico publicado en 2011

Molecular mechanisms of Streptococcus pneumoniae-targeted autophagy via pneumolysin, Golgi-resident Rab41, and Nedd4-1-mediated K63-linked ubiquitination

artículo científico publicado en 2018

Mon1-Ccz1 activates Rab7 only on late endosomes and dissociates from the lysosome in mammalian cells

artículo científico publicado en 2015

Multiple Roles of VARP in Endosomal Trafficking: Rabs, Retromer Components and R-SNARE VAMP7 Meet on VARP

artículo científico publicado en 2016

Multiple Types of Guanine Nucleotide Exchange Factors (GEFs) for Rab Small GTPases.

artículo científico publicado en 2016

Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets.

artículo científico publicado en 2003

Mutation of the pleckstrin homology domain of Bruton's tyrosine kinase in immunodeficiency impaired inositol 1,3,4,5-tetrakisphosphate binding capacity

scientific article published on 01 November 1996

Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells

artículo científico publicado en 2007

NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by switching binding specificity from phosphatidylserine to Sec15 ⬇️

artículo científico publicado el 22 de febrero de 2013

Nerve growth factor-dependent sorting of synaptotagmin IV protein to mature dense-core vesicles that undergo calcium-dependent exocytosis in PC12 cells.

artículo científico publicado en 2002

Neuronal calcium sensor-1 and phosphatidylinositol 4-kinase beta stimulate extracellular signal-regulated kinase 1/2 signaling by accelerating recycling through the endocytic recycling compartment.

artículo científico publicado en 2006

Non-polarized distribution of synaptotagmin IV in neurons: evidence that synaptotagmin IV is not a synaptic vesicle protein

scientific journal article

Novel splicing isoforms of synaptotagmin-like proteins 2 and 3: identification of the Slp homology domain

scientific journal article

OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation

artículo científico publicado en 2011

P53- and mevalonate pathway-driven malignancies require Arf6 for metastasis and drug resistance.

artículo científico publicado en 2016

Parkin promotes proteasomal degradation of synaptotagmin IV by accelerating polyubiquitination.

artículo científico publicado en 2017

Parkinson's disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking

artículo científico publicado en 2018

Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis

artículo científico publicado en 2010

Phospholipase C-related but Catalytically Inactive Protein (PRIP) Modulates Synaptosomal-associated Protein 25 (SNAP-25) Phosphorylation and Exocytosis ⬇️

artículo científico publicado el 6 de febrero de 2012

Phosphorylation of AATYK1 by Cdk5 suppresses its tyrosine phosphorylation

artículo científico publicado en 2010

Plasmalemmal sealing of transected mammalian neurites is a gradual process mediated by Ca(2+)-regulated proteins.

artículo científico publicado en 2003

Polymorphic hemoglobin from a midge larva (Tokunagayusurika akamusi) can be divided into two different types.

artículo científico publicado en 1993

Presynaptic injection of syntaxin-specific antibodies blocks transmission in the squid giant synapse.

artículo científico publicado en 1998

Protein kinase C-mediated phosphorylation of the two polybasic regions of synaptotagmin VI regulates their function in acrosomal exocytosis.

artículo científico publicado en 2005

Proteomics analysis of insulin secretory granules.

artículo científico publicado en 2007

RNA interference-mediated silencing of synaptotagmin IX, but not synaptotagmin I, inhibits dense-core vesicle exocytosis in PC12 cells

scientific journal article

RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes

scientific journal article

Rab GTPases: key players in melanosome biogenesis, transport, and transfer

scientific article published on 30 September 2020

Rab family of small GTPases: an updated view on their regulation and functions

artículo científico publicado en 2020

Rab10 in insulin-stimulated GLUT4 translocation.

artículo científico publicado en 2008

Rab10 regulates tubular endosome formation through KIF13A and KIF13B motors

scientific article published on 19 February 2019

Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane

scientific journal article

Rab11a-Rab8a cascade regulates the formation of tunneling nanotubes through vesicle recycling

artículo científico publicado en 2018

Rab12 Regulates Retrograde Transport of Mast Cell Secretory Granules by Interacting with the RILP-Dynein Complex.

artículo científico publicado en 2016

Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4.

artículo científico publicado en 2013

Rab13 acts downstream of the kinase Mst1 to deliver the integrin LFA-1 to the cell surface for lymphocyte trafficking.

artículo científico publicado en 2014

Rab1A regulates anterograde melanosome transport by recruiting kinesin-1 to melanosomes through interaction with SKIP.

artículo científico publicado en 2015

Rab20, a novel Rab small GTPase that negatively regulates neurite outgrowth of PC12 cells

artículo científico publicado en 2017

Rab27 effector Slp2-a transports the apical signaling molecule podocalyxin to the apical surface of MDCK II cells and regulates claudin-2 expression.

artículo científico publicado en 2012

Rab27 effectors, pleiotropic regulators in secretory pathways.

artículo científico

Rab27A regulates transport of cell surface receptors modulating multinucleation and lysosome-related organelles in osteoclasts.

artículo científico publicado en 2015

Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes.

artículo científico publicado en 2004

Rab27a and Rab27b control different steps of the exosome secretion pathway

artículo científico publicado en 2010

Rab27a regulates epithelial sodium channel (ENaC) activity through synaptotagmin-like protein (SLP-5) and Munc13-4 effector mechanism

artículo científico publicado en 2006

Rab27a regulates exocytosis of tertiary and specific granules in human neutrophils.

artículo científico publicado en 2008

Rab32 subfamily small GTPases: pleiotropic Rabs in endosomal trafficking

artículo científico publicado en 2017

Rab33a mediates anterograde vesicular transport for membrane exocytosis and axon outgrowth.

artículo científico publicado en 2012

Rab35 Functions in Axon Elongation Are Regulated by P53-Related Protein Kinase in a Mechanism That Involves Rab35 Protein Degradation and the Microtubule-Associated Protein 1B.

artículo científico publicado en 2016

Rab35 and its GAP EPI64C in T cells regulate receptor recycling and immunological synapse formation.

artículo científico publicado en 2008

Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth

scientific journal article

Rab35 is translocated from Arf6-positive perinuclear recycling endosomes to neurite tips during neurite outgrowth.

artículo científico publicado en 2014

Rab35 promotes the recruitment of Rab8, Rab13 and Rab36 to recycling endosomes through MICAL-L1 during neurite outgrowth

artículo científico publicado en 2014

Rab35 regulates Arf6 activity through centaurin-β2 (ACAP2) during neurite outgrowth

artículo científico publicado en 2012

Rab35 regulates phagosome formation through recruitment of ACAP2 in macrophages during Fc R-mediated phagocytosis

scientific article published on 01 November 2011

Rab35-GEFs, DENND1A and folliculin differentially regulate podocalyxin trafficking in two- and three-dimensional epithelial cell cultures

artículo científico publicado en 2020

Rab38 targets to lamellar bodies and normalizes their sizes in lung alveolar type II epithelial cells ⬇️

artículo científico publicado el 15 de julio de 2011

Rab3A and Rab27A cooperatively regulate the docking step of dense-core vesicle exocytosis in PC12 cells

scientific article published on 09 May 2006

Rab3A, a possible marker of cortical granules, participates in cortical granule exocytosis in mouse eggs

artículo científico publicado en 2016

Rab40C is a novel Varp-binding protein that promotes proteasomal degradation of Varp in melanocytes

artículo científico publicado en 2015

Rab5 activation on macropinosomes requires ALS2, and subsequent Rab5 inactivation through ALS2 detachment requires active Rab7

scientific article published on 07 December 2018

Rab5 is a novel regulator of mast cell secretory granules: impact on size, cargo, and exocytosis

artículo científico publicado en 2014

Rab5 is critical for SNAP23 regulated granule-granule fusion during compound exocytosis.

artículo científico publicado en 2017

Rab7 knockout unveiled regulated autolysosome maturation induced by glutamine starvation

artículo científico publicado en 2018

Rabex-5 protein regulates dendritic localization of small GTPase Rab17 and neurite morphogenesis in hippocampal neurons

artículo científico publicado en 2013

Rabin8 regulates neurite outgrowth in both GEF activity-dependent and -independent manners

artículo científico publicado en 2016

Rabin8 suppresses autophagosome formation independently of its guanine nucleotide-exchange activity towards Rab8.

artículo científico publicado en 2015

Rabphilin and Noc2 are recruited to dense-core vesicles through specific interaction with Rab27A in PC12 cells

scientific journal article

Recent advances in understanding the molecular basis of melanogenesis in melanocytes

artículo científico publicado en 2020

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin.

artículo científico publicado en 2013

Regulation by bivalent cations of phospholipid binding to the C2A domain of synaptotagmin III.

artículo científico publicado en 1997

Regulation of AP-2-synaptotagmin interaction by inositol high polyphosphates.

artículo científico publicado en 1997

Regulation of podocalyxin trafficking by Rab small GTPases in 2D and 3D epithelial cell cultures.

artículo científico publicado en 2016

Regulation of podocalyxin trafficking by Rab small GTPases in epithelial cells.

artículo científico publicado en 2016

Regulation of synaptic transmission by RAB-3 and RAB-27 in Caenorhabditis elegans

artículo científico publicado en 2006

Release of Infectious Hepatitis C Virus from Huh7 Cells Occurs via a trans-Golgi Network-to-Endosome Pathway Independent of Very-Low-Density Lipoprotein Secretion ⬇️

artículo científico publicado en 2016

Revisiting Rab7 Functions in Mammalian Autophagy: Rab7 Knockout Studies

Role of Rab family GTPases and their effectors in melanosomal logistics.

artículo científico

Role of Rab27 in synaptic transmission at the squid giant synapse

artículo científico publicado en 2008

Role of the C2A domain of synaptotagmin in transmitter release as determined by specific antibody injection into the squid giant synapse preterminal.

artículo científico publicado en 1995

Role of the C2B domain of synaptotagmin in vesicular release and recycling as determined by specific antibody injection into the squid giant synapse preterminal.

artículo científico publicado en 1995

Roles of synaptotagmin C2 domains in neurotransmitter secretion and inositol high-polyphosphate binding at mammalian cholinergic synapses

artículo científico publicado en 1997

SNARE dynamics during melanosome maturation

artículo científico publicado en 2018

Selective photoaffinity labeling of the inositol polyphosphate binding C2B domains of synaptotagmins

scientific article published on 01 February 1997

Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells

artículo científico publicado en 2016

Slac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actin

scientific journal article

Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse

artículo científico publicado en 2008

Slp2-a controls renal epithelial cell size through regulation of Rap-ezrin signaling independently of Rab27

artículo científico publicado en 2014

Slp2-a inactivates ezrin by recruiting protein phosphatase 1 to the plasma membrane

artículo científico publicado en 2015

Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells

artículo científico publicado en 2003

Slp4-a/granuphilin-a interacts with syntaxin-2/3 in a Munc18-2-dependent manner

artículo científico publicado en 2005

Small GTPase Rab12 regulates constitutive degradation of transferrin receptor

scientific journal article

Small GTPase Rab17 regulates dendritic morphogenesis and postsynaptic development of hippocampal neurons

scientific journal article

Small GTPase Rab17 regulates the surface expression of kainate receptors but not α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in hippocampal neurons via dendritic trafficking of Syntaxin-4 protein.

artículo científico publicado en 2014

Small GTPase Rab2B and Its Specific Binding Protein Golgi-associated Rab2B Interactor-like 4 (GARI-L4) Regulate Golgi Morphology

artículo científico publicado en 2015

Small GTPase Rab39A interacts with UACA and regulates the retinoic acid-induced neurite morphology of Neuro2A cells

scientific journal article

Small Interfering RNA Screening for the Small GTPase Rab Proteins Identifies Rab5B as a Major Regulator of Hepatitis B Virus Production

artículo científico publicado en 2019

Spatial segregation of degradation- and recycling-trafficking pathways in COS-1 cells

artículo científico publicado en 2007

Specific TBC Domain-Containing Proteins Control the ER-Golgi-Plasma Membrane Trafficking of GPCRs

scientific article published on 01 July 2019

Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases

artículo científico publicado en 2008

Structure-function analyses of the small GTPase Rab35 and its effector protein centaurin-β2/ACAP2 during neurite outgrowth of PC12 cells.

artículo científico

Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes.

artículo científico publicado en 2010

Structure-function relationships of the mouse Gap1m. Determination of the inositol 1,3,4,5-tetrakisphosphate-binding domain.

artículo científico publicado en 1996

Synaptotagmin (Syt) IX is an essential determinant for protein sorting to secretory granules in mast cells.

artículo científico publicado en 2006

Synaptotagmin I and IV are differentially regulated in the brain by the recreational drug 3,4-methylenedioxymethamphetamine (MDMA).

artículo científico publicado en 2002

Synaptotagmin I and IV define distinct populations of neuronal transport vesicles

scientific article published on 01 April 2000

Synaptotagmin I binds intestinal epithelial NHE3 and mediates cAMP- and Ca2+-induced endocytosis by recruitment of AP2 and clathrin

scientific article published on 15 February 2007

Synaptotagmin IV acts as a multi-functional regulator of Ca2+-dependent exocytosis

scientific journal article

Synaptotagmin IV is present at the Golgi and distal parts of neurites

scientific journal article

Synaptotagmin IV regulates glial glutamate release

scientific journal article

Synaptotagmin IX Regulates Ca2+-dependent Secretion in PC12 Cells ⬇️

artículo científico publicado el 21 de diciembre de 2001

Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules.

artículo científico publicado en 2003

Synaptotagmin V and IX isoforms control Ca2+ -dependent insulin exocytosis.

artículo científico publicado en 2004

Synaptotagmin V is targeted to dense-core vesicles that undergo calcium-dependent exocytosis in PC12 cells

scientific journal article

Synaptotagmin VII is targeted to dense-core vesicles and regulates their Ca2+ -dependent exocytosis in PC12 cells.

artículo científico publicado en 2004

Synaptotagmin XI Regulates Phagocytosis and Cytokine Secretion in Macrophages ⬇️

artículo científico publicado el 9 de enero de 2013

Synaptotagmin interaction with the syntaxin/SNAP-25 dimer is mediated by an evolutionarily conserved motif and is sensitive to inositol hexakisphosphate

artículo científico publicado en 2004

Synaptotagmin is an inositol polyphosphate binding protein: isolation and characterization as an Ins 1,3,4,5-P4 binding protein

scientific article published on 01 December 1994

Synaptotagmin-like protein (Slp) homology domain 1 of Slac2-a/melanophilin is a critical determinant of GTP-dependent specific binding to Rab27A.

artículo científico publicado en 2002

Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells

artículo científico publicado en 2012

Syntaxin-3 is required for melanosomal localization of Tyrp1 in melanocytes

scientific journal article

TBC proteins: GAPs for mammalian small GTPase Rab?

artículo científico publicado en 2011

TBC1D12 is a novel Rab11-binding protein that modulates neurite outgrowth of PC12 cells

artículo científico publicado en 2017

TBC1D9B functions as a GTPase-activating protein for Rab11a in polarized MDCK cells

artículo científico publicado en 2014

The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy

artículo científico publicado en 2008

The BLOC-3 subunit HPS4 is required for activation of Rab32/38 GTPases in melanogenesis, but its Rab9 activity is dispensable for melanogenesis

artículo científico publicado en 2019

The C2A domain of double C2 protein gamma contains a functional nuclear localization signal

artículo científico publicado en 2001

The C2A domain of synaptotagmin-like protein 3 (Slp3) is an atypical calcium-dependent phospholipid-binding machine: comparison with the C2A domain of synaptotagmin I.

artículo científico publicado en 2002

The GTPase Rab37 Participates in the Control of Insulin Exocytosis

artículo científico publicado en 2013

The GTPase Rab43 Controls the Anterograde ER-Golgi Trafficking and Sorting of GPCRs

artículo científico publicado en 2017

The GTPase-deficient Rab27A(Q78L) mutant inhibits melanosome transport in melanocytes through trapping of Rab27A effector protein Slac2-a/melanophilin in their cytosol: development of a novel melanosome-targetinG tag.

artículo científico publicado en 2014

The LMTK1-TBC1D9B-Rab11A Cascade Regulates Dendritic Spine Formation via Endosome Trafficking

scientific article published on 18 October 2019

The Leishmania donovani lipophosphoglycan excludes the vesicular proton-ATPase from phagosomes by impairing the recruitment of synaptotagmin V.

artículo científico publicado en 2009

The N-terminal cysteine cluster is essential for membrane targeting of B/K protein ⬇️

artículo científico publicado el 1 de diciembre de 2001

The Rab interacting lysosomal protein (RILP) homology domain functions as a novel effector domain for small GTPase Rab36: Rab36 regulates retrograde melanosome transport in melanocytes.

artículo científico publicado en 2012

The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes

scientific journal article

The Slp Homology Domain of Synaptotagmin-like Proteins 1–4 and Slac2 Functions as a Novel Rab27A Binding Domain ⬇️

artículo científico publicado el 31 de diciembre de 2001

The Slp4-a linker domain controls exocytosis through interaction with Munc18-1.syntaxin-1a complex.

artículo científico publicado en 2006

The calcium-binding loops of the tandem C2 domains of synaptotagmin VII cooperatively mediate calcium-dependent oligomerization.

artículo científico publicado en 2002

The drs tumor suppressor is involved in the maturation process of autophagy induced by low serum

scientific journal article

The extra-cellular signal regulated kinases ERK1 and ERK2 segregate displaying distinct spatiotemporal characteristics in activated mast cells

artículo científico publicado en 2013

The first C2 domain of synaptotagmin is required for exocytosis of insulin from pancreatic beta-cells: action of synaptotagmin at low micromolar calcium.

artículo científico publicado en 1997

The function of inositol high polyphosphate binding proteins ⬇️

artículo científico publicado el 1 de julio de 1997

The host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole

artículo científico publicado en 2019

The inositol high-polyphosphate series blocks synaptic transmission by preventing vesicular fusion: a squid giant synapse study.

artículo científico publicado en 1994

The pH-dependent swinging-out of the distal histidine residue in ferric hemoglobin of a midge larva (Tokunagayusurika akamusi).

artículo científico publicado en 1994

The polybasic sequence in the C2B domain of rabphilin is required for the vesicle docking step in PC12 cells

scientific article published on 29 November 2006

The primate-specific protein TBC1D3 is required for optimal macropinocytosis in a novel ARF6-dependent pathway

artículo científico publicado en 2008

The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking

scientific journal article

The secretory granule-associated protein CAPS2 regulates neurotrophin release and cell survival

scientific journal article

The short apical membrane half-life of rescued {Delta}F508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of {Delta}F508-CFTR in polarized human airway epithelial cells

artículo científico publicado en 2005

The small GTPase Rab33A participates in regulation of amylase release from parotid acinar cells

artículo científico

Versatile role of Rab27 in membrane trafficking: focus on the Rab27 effector families.

artículo científico publicado en 2005

Versatile roles of R-Ras GAP in neurite formation of PC12 cells and embryonic vascular development

artículo científico publicado en 2006

Vesicle-associated membrane protein-2/synaptobrevin binding to synaptotagmin I promotes O-glycosylation of synaptotagmin I.

artículo científico publicado en 2002

Vesicular reuptake inhibition by a synaptotagmin I C2B domain antibody at the squid giant synapse

artículo científico publicado en 2004

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

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