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Lista de obras de Nicholas Pugh

A role for adhesion and degranulation-promoting adapter protein in collagen-induced platelet activation mediated via integrin α(2) β(1)

artículo científico publicado en 2012

Agonist-Evoked Increases in Intra-Platelet Zinc Couple to Functional Responses

article

Anti-thrombotic efficacy of S007-867: Pre-clinical evaluation in experimental models of thrombosis in vivo and in vitro.

artículo científico publicado en 2018

Cell-collagen interactions: the use of peptide Toolkits to investigate collagen-receptor interactions.

artículo científico publicado en 2008

Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood

artículo científico publicado en 2012

Differential integrin activity mediated by platelet collagen receptor engagement under flow conditions.

artículo científico publicado en 2017

Dynamic analysis of platelet deposition to resolve platelet adhesion receptor activity in whole blood at arterial shear rate.

artículo científico publicado en 2014

Expression of the Ian family of putative GTPases during T cell development and description of an Ian with three sets of GTP/GDP-binding motifs

scientific journal article

Extracellular chloride is required for efficient platelet aggregation.

artículo científico

Identification of platelet function defects by multi-parameter assessment of thrombus formation

artículo científico publicado en 2014

MMP-13 binds to platelet receptors αIIbβ3 and GPVI and impairs aggregation and thrombus formation

artículo científico publicado en 2018

Modified platelet deposition on matrix metalloproteinase 13 digested collagen I.

artículo científico publicado en 2015

Monitoring the intracellular store Ca2+ concentration in agonist-stimulated, intact human platelets by using Fluo-5N

scientific article published on 01 March 2011

OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice

artículo científico publicado en 2011

Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets.

artículo científico publicado en 2013

Probing luminal negative charge in the type 3 ryanodine receptor.

artículo científico publicado en 2005

Putative GTPase GIMAP1 is critical for the development of mature B and T lymphocytes

scientific journal article

Single domain antibodies against the collagen signalling receptor glycoprotein VI are inhibitors of collagen induced thrombus formation

artículo científico publicado en 2009

Stapled peptides as a new technology to investigate protein-protein interactions in human platelets.

artículo científico publicado en 2018

The contribution of zinc to platelet behaviour during haemostasis and thrombosis.

artículo científico

The impact of factor Xa inhibition on axial dependent arterial thrombus formation triggered by a tissue factor rich surface.

artículo científico publicado en 2012

The properties conferred upon triple-helical collagen-mimetic peptides by the presence of cysteine residues.

artículo científico publicado en 2012

Thrombospondin-1 promotes matrix homeostasis by interacting with collagen and lysyl oxidase precursors and collagen cross-linking sites

artículo científico publicado en 2018

Zinc is a transmembrane agonist that induces platelet activation in a tyrosine phosphorylation-dependent manner.

artículo científico publicado en 2015

Zinc regulates reactive oxygen species generation in platelets

scientific article published on 05 April 2020

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