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Lista de obras de Dickson TC

A Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During Disease

artículo científico publicado en 2016

Acute reactive and regenerative changes in mature cortical axons following injury.

artículo científico publicado en 2007

Alpha-synuclein is upregulated in neurones in response to chronic oxidative stress and is associated with neuroprotection.

artículo científico publicado en 2005

Altered synapses and gliotransmission in Alzheimer's disease and AD model mice.

artículo científico publicado en 2013

Amyloid β precursor protein regulates neuron survival and maturation in the adult mouse brain

artículo científico publicado en 2016

Amyotrophic lateral sclerosis associated mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex

artículo científico publicado en 2020

Amyotrophic lateral sclerosis mutant TDP-43 may cause synaptic dysfunction through altered dendritic spine function

scientific article published on 17 May 2019

Axonal degeneration, distal collateral branching and neuromuscular junction architecture alterations occur prior to symptom onset in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

artículo científico publicado en 2016

Axonal shearing in mature cortical neurons induces attempted regeneration and the reestablishment of neurite polarity

artículo científico publicado en 2009

Axonopathy and cytoskeletal disruption in degenerative diseases of the central nervous system.

artículo científico publicado en 2009

Binding partners L1 cell adhesion molecule and the ezrin-radixin-moesin (ERM) proteins are involved in development and the regenerative response to injury of hippocampal and cortical neurons

scientific journal article

Calretinin and Neuropeptide Y interneurons are differentially altered in the motor cortex of the SOD1G93A mouse model of ALS.

artículo científico publicado en 2017

Chronic excitotoxin-induced axon degeneration in a compartmented neuronal culture model

artículo científico publicado en 2012

Cortical murine neurons lacking the neurofilament light chain protein have an attenuated response to injury in vitro.

artículo científico publicado en 2013

Cyclosporin-A treatment attenuates delayed cytoskeletal alterations and secondary axotomy following mild axonal stretch injury.

artículo científico publicado en 2007

Cytoplasmic cytochrome c immunolabelling in dystrophic neurites in Alzheimer's disease.

artículo científico publicado en 2006

Cytoskeletal alterations differentiate presenilin-1 and sporadic Alzheimer's disease

artículo científico publicado en 2008

Cytoskeletal changes during development and aging in the cortex of neurofilament light protein knockout mice

artículo científico publicado en 2013

Degeneration of axons in spinal white matter in G93A mSOD1 mouse characterized by NFL and α-internexin immunoreactivity

artículo científico publicado en 2012

Denervation of the olfactory bulb leads to decreased Aβ plaque load in a transgenic mouse model of Alzheimer' s disease

artículo científico publicado en 2013

Direct determination of the proportion of intra- and extra-cellular neocortical neurofibrillary tangles in Alzheimer's disease.

artículo científico publicado en 2003

Disruption of the ubiquitin proteasome system following axonal stretch injury accelerates progression to secondary axotomy.

artículo científico publicado en 2009

Does beta-amyloid plaque formation cause structural injury to neuronal processes?

artículo científico publicado en 2005

Dystrophic neurites in TgCRND8 and Tg2576 mice mimic human pathological brain aging.

artículo científico publicado en 2007

ERM proteins regulate growth cone responses to Sema3A

artículo científico publicado en 2008

ERMs colocalize transiently with L1 during neocortical axon outgrowth

scientific journal article

Efficacy of epothilones in central nervous system trauma treatment: what has age got to do with it?

artículo científico publicado en 2021

Epothilone D accelerates disease progression in the SOD1G93A mouse model of Amyotrophic Lateral Sclerosis

artículo científico publicado en 2018

Epothilone D inhibits microglia-mediated spread of alpha-synuclein aggregates

artículo científico publicado en 2018

Excitotoxicity mediated by non-NMDA receptors causes distal axonopathy in long-term cultured spinal motor neurons.

artículo científico publicado en 2007

Focal damage to the adult rat neocortex induces wound healing accompanied by axonal sprouting and dendritic structural plasticity

artículo científico publicado en 2010

Focal demyelination in Alzheimer's disease and transgenic mouse models.

artículo científico publicado en 2010

Functional binding interaction identified between the axonal CAM L1 and members of the ERM family

artículo científico publicado en 2002

Identification and characterization of a population of motile neurons in long-term cortical culture.

artículo científico publicado en 2007

Identifying the primary site of pathogenesis in amyotrophic lateral sclerosis - vulnerability of lower motor neurons to proximal excitotoxicity

artículo científico publicado en 2015

Inducing Chronic Excitotoxicity in the Mouse Spinal Cord to Investigate Lower Motor Neuron Degeneration

artículo científico publicado en 2016

Inhibitory dysfunction in amyotrophic lateral sclerosis: future therapeutic opportunities

artículo científico publicado en 2015

Initial calcium release from intracellular stores followed by calcium dysregulation is linked to secondary axotomy following transient axonal stretch injury

artículo científico publicado en 2009

Intrinsic regenerative ability of mature CNS neurons.

artículo científico publicado en 2004

Localization of glutamate receptors in developing cortical neurons in culture and relationship to susceptibility to excitotoxicity.

artículo científico publicado en 2006

Microfluidic Device for Studying Traumatic Brain Injury

Microfluidic culture platform for studying neuronal response to mild to very mild axonal stretch injury.

artículo científico publicado en 2014

Microfluidic primary culture model of the lower motor neuron-neuromuscular junction circuit

artículo científico publicado en 2013

Mild Traumatic Brain Injury Leads to Decreased Inhibition and a Differential Response of Calretinin Positive Interneurons in the Injured Cortex.

artículo científico publicado en 2017

Mild and repetitive very mild axonal stretch injury triggers cystoskeletal mislocalization and growth cone collapse

artículo científico publicado en 2017

Mild axonal stretch injury in vitro induces a progressive series of neurofilament alterations ultimately leading to delayed axotomy

artículo científico publicado en 2005

Neurites containing the neurofilament-triplet proteins are selectively vulnerable to cytoskeletal pathology in Alzheimer's disease and transgenic mouse models.

artículo científico publicado en 2013

Neurochemical diversity of dystrophic neurites in the early and late stages of Alzheimer's disease.

artículo científico publicado en 1999

Neurofilament triplet proteins are restricted to a subset of neurons in the rat neocortex.

artículo científico publicado en 2002

Neuroprotective upregulation of endogenous α-synuclein precedes ubiquitination in cultured dopaminergic neurons.

artículo científico publicado en 2010

No difference in expression of apoptosis-related proteins and apoptotic morphology in control, pathologically aged and Alzheimer's disease cases

scientific article published on 09 January 2006

Olfactory ensheathing cells promote neurite sprouting of injured axons in vitro by direct cellular contact and secretion of soluble factors

scientific article published on 01 May 2004

Pathogenic or protective? Neuropeptide Y in amyotrophic lateral sclerosis

scientific article published on 12 July 2020

Physical damage to rat cortical axons mimics early Alzheimer's neuronal pathology.

artículo científico publicado en 1997

Reduced Excitability and Increased Neurite Complexity of Cortical Interneurons in a Familial Mouse Model of Amyotrophic Lateral Sclerosis

artículo científico publicado en 2018

Relationship between apolipoprotein E and the amyloid deposits and dystrophic neurites of Alzheimer's disease

artículo científico publicado en 1997

Rho kinase activates ezrin-radixin-moesin (ERM) proteins and mediates their function in cortical neuron growth, morphology and motility in vitro

artículo científico publicado en 2007

Sequence of cellular changes following localized axotomy to cortical neurons in glia-free culture

artículo científico publicado en 2000

Stainless steel pinholes for fast fabrication of high-performance microchip electrophoresis devices by CO2 laser ablation

artículo científico publicado en 2013

Synapse Dysfunction of Layer V Pyramidal Neurons Precedes Neurodegeneration in a Mouse Model of TDP-43 Proteinopathies.

artículo científico publicado en 2016

The Microtubule-Modulating Drug Epothilone D Alters Dendritic Spine Morphology in a Mouse Model of Mild Traumatic Brain Injury

artículo científico publicado en 2018

The cause of neuronal degeneration in Alzheimer's disease

artículo científico publicado en 2000

The degree of astrocyte activation in multiple system atrophy is inversely proportional to the distance to α-synuclein inclusions

artículo científico publicado en 2015

The microtubule-stabilizing drug Epothilone D increases axonal sprouting following transection injury in vitro.

artículo científico publicado en 2015

The morphological phenotype of beta-amyloid plaques and associated neuritic changes in Alzheimer's disease

artículo científico publicado en 2001

The pathologic outcomes and efficacy of epothilone treatment following traumatic brain injury is determined by age

artículo científico publicado en 2020

Vaccination Strategies for Alzheimer???s Disease

artículo científico publicado en 2007

alpha-Internexin immunoreactivity reflects variable neuronal vulnerability in Alzheimer's disease and supports the role of the beta-amyloid plaques in inducing neuronal injury

artículo científico publicado en 2005

α-Synuclein protects neurons from apoptosis downstream of free-radical production through modulation of the MAPK signalling pathway.

artículo científico publicado en 2012