Lista de obras - Lawrence Paul Wennogle - Dominio Público Uruguay

5-Aryl-3-azabicyclo[3.2.0]heptan-6-one ketals, compounds with morphine-like analgesic activity

artículo científico publicado en 1984

A fluorometric assay for peptidyl alpha-amidation activity using high-performance liquid chromatography.

artículo científico publicado en 1988

Allosteric interaction between the site labeled by [3H]imipramine and the serotonin transporter in human platelets

artículo científico publicado en 1987

Backbone resonance assignment of the 298 amino acid catalytic domain of protein tyrosine phosphatase 1B (PTP1B).

artículo científico publicado en 2002

C5a receptor antagonists.

artículo científico publicado en 1999

Characterization of the binding of Bolton-Hunter labeled [125I]C5a to human neutrophil, monocyte and U-937 cell membranes

scientific article published on 01 November 1992

Characterization, crystallization and preliminary crystallographic analysis of human recombinant cyclooxygenase-2.

artículo científico publicado en 1997

Comparison of recombinant cyclooxygenase-2 to native isoforms: aspirin labeling of the active site

artículo científico publicado en 1995

Conditions for the selective labelling of the 66 000 dalton chain of the acetylcholine receptor by the covalent non-competitive blocker 5-azido-[3H]trimethisoquin

artículo científico publicado en 1980

Covalent attachment of polydeoxythymidylic acid to human erythrocytes

artículo científico publicado en 1978

Differential effects of PDE5 inhibitors on cardiac dysfunction in the MDX ouse model of Duchenne muscular dystrophy.

artículo científico publicado en 2013

Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases

artículo científico publicado en 2016

Discovery of a tetracyclic quinoxaline derivative as a potent and orally active multifunctional drug candidate for the treatment of neuropsychiatric and neurological disorders.

artículo científico publicado en 2014

Dissection of the 66 000-dalton subunit of the acetylcholine receptor

scientific article published on 01 April 1981

Effect of chronic desmethylimipramine or electroconvulsive shock on selected brain and platelet neurotransmitter recognition sites

artículo científico publicado en 1985

Exposure of human vascular smooth muscle cells to Raf-1 antisense oligodeoxynucleotides: cellular responses and pharmacodynamic implications

scientific article published on 01 January 1998

Factors regulating the susceptibility of the acetylcholine receptor protein to heat inactivation ⬇️

artículo científico publicado en 1979

Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease

artículo científico publicado en 2010

Human brain receptor alterations in suicide victims

scientific article published on 01 July 1982

Human platelet imipramine recognition sites: biochemical and pharmacological characterization

scientific article published on 01 December 1981

Identification of protease 3.4.24.11 as the major atrial natriuretic factor degrading enzyme in the rat kidney

artículo científico publicado en 1988

Isolation of cell surface proteins by hybridization

scientific article published on 01 October 1978

Mapping the subsite preferences of protein tyrosine phosphatase PTP-1B using combinatorial chemistry approaches.

artículo científico publicado en 1998

Molecular and cellular characterization of baboon C-Raf as a target for antiproliferative effects of antisense oligonucleotides.

artículo científico publicado en 1997

Nose-to-brain transport of imatinib mesylate: A pharmacokinetic evaluation.

artículo científico publicado en 2017

Novel C5a receptor antagonists regulate neutrophil functions in vitro and in vivo.

artículo científico publicado en 1998

Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis

artículo científico publicado en 2003

Phosphodiesterase 1: A Unique Drug Target for Degenerative Diseases and Cognitive Dysfunction.

artículo científico publicado en 2017

Phosphodiesterase Inhibition and Regulation of Dopaminergic Frontal and Striatal Functioning: Clinical Implications

artículo científico publicado en 2016

Phospholipase D regulation by a physical interaction with the actin-binding protein gelsolin

artículo científico publicado en 1996

Preclinical profile of ITI-214, an inhibitor of phosphodiesterase 1, for enhancement of memory performance in rats.

artículo científico publicado en 2016

Profiling of inhibitors of protein kinase C

artículo científico publicado en 1988

Radioiodination of transforming growth factor-beta (TGF-beta) in a modified Bolton-Hunter reaction system

scientific article published on 01 July 1993

Serotonin modulates the dissociation of [3H]imipramine from human platelet recognition sites

scientific article published on 01 December 1982

Serotonin uptake inhibitors differentially modulate high affinity imipramine dissociation in human platelet membranes

scientific article published on 01 April 1985

Stabilization of C5a receptor--G-protein interactions through ligand binding

artículo científico publicado en 1994

Substrate phosphorylation can inhibit proteolysis by trypsin-like enzymes

artículo científico publicado en 1989

Synthesis and analgesic activity of 5-aryl-3-azabicyclo [3.2.0.] heptan-6-one dimethylacetals: compounds with extraordinary morphine-like properties

scientific article published on 01 April 1983

Synthesis and antiproliferative activity of 7-azaindirubin-3'-oxime, a 7-aza isostere of the natural indirubin pharmacophore.

artículo científico publicado en 2009

The RAF family: an expanding network of post-translational controls and protein-protein interactions.

artículo científico publicado en 1998

The discovery and characterization of an interleukin 6 cytokine family antagonist protein from a marine sponge, Callyspongia sp

scientific article published on 01 January 2001

The role of the C-terminal domain of protein tyrosine phosphatase-1B in phosphatase activity and substrate binding

artículo científico publicado en 2007

Transmembrane orientation of proteins present in acetylcholine receptor-rich membranes from Torpedo marmorata studied by selective proteolysis

artículo científico publicado en 1980

Lista de obras de Lawrence Paul Wennogle

5-Aryl-3-azabicyclo[3.2.0]heptan-6-one ketals, compounds with morphine-like analgesic activity

A fluorometric assay for peptidyl alpha-amidation activity using high-performance liquid chromatography.

Allosteric interaction between the site labeled by [3H]imipramine and the serotonin transporter in human platelets

Backbone resonance assignment of the 298 amino acid catalytic domain of protein tyrosine phosphatase 1B (PTP1B).

C5a receptor antagonists.

Characterization of the binding of Bolton-Hunter labeled [125I]C5a to human neutrophil, monocyte and U-937 cell membranes

Characterization, crystallization and preliminary crystallographic analysis of human recombinant cyclooxygenase-2.

Comparison of recombinant cyclooxygenase-2 to native isoforms: aspirin labeling of the active site

Conditions for the selective labelling of the 66 000 dalton chain of the acetylcholine receptor by the covalent non-competitive blocker 5-azido-[3H]trimethisoquin

Covalent attachment of polydeoxythymidylic acid to human erythrocytes

Differential effects of PDE5 inhibitors on cardiac dysfunction in the MDX ouse model of Duchenne muscular dystrophy.

Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases

Discovery of a tetracyclic quinoxaline derivative as a potent and orally active multifunctional drug candidate for the treatment of neuropsychiatric and neurological disorders.

Dissection of the 66 000-dalton subunit of the acetylcholine receptor

Effect of chronic desmethylimipramine or electroconvulsive shock on selected brain and platelet neurotransmitter recognition sites

Exposure of human vascular smooth muscle cells to Raf-1 antisense oligodeoxynucleotides: cellular responses and pharmacodynamic implications

Factors regulating the susceptibility of the acetylcholine receptor protein to heat inactivation ⬇️

Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease

Human brain receptor alterations in suicide victims

Human platelet imipramine recognition sites: biochemical and pharmacological characterization

Identification of protease 3.4.24.11 as the major atrial natriuretic factor degrading enzyme in the rat kidney

Isolation of cell surface proteins by hybridization

Mapping the subsite preferences of protein tyrosine phosphatase PTP-1B using combinatorial chemistry approaches.

Molecular and cellular characterization of baboon C-Raf as a target for antiproliferative effects of antisense oligonucleotides.

Nose-to-brain transport of imatinib mesylate: A pharmacokinetic evaluation.

Novel C5a receptor antagonists regulate neutrophil functions in vitro and in vivo.

Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis

Phosphodiesterase 1: A Unique Drug Target for Degenerative Diseases and Cognitive Dysfunction.

Phosphodiesterase Inhibition and Regulation of Dopaminergic Frontal and Striatal Functioning: Clinical Implications

Phospholipase D regulation by a physical interaction with the actin-binding protein gelsolin

Preclinical profile of ITI-214, an inhibitor of phosphodiesterase 1, for enhancement of memory performance in rats.

Profiling of inhibitors of protein kinase C

Radioiodination of transforming growth factor-beta (TGF-beta) in a modified Bolton-Hunter reaction system

Serotonin modulates the dissociation of [3H]imipramine from human platelet recognition sites

Serotonin uptake inhibitors differentially modulate high affinity imipramine dissociation in human platelet membranes

Stabilization of C5a receptor--G-protein interactions through ligand binding

Substrate phosphorylation can inhibit proteolysis by trypsin-like enzymes

Synthesis and analgesic activity of 5-aryl-3-azabicyclo [3.2.0.] heptan-6-one dimethylacetals: compounds with extraordinary morphine-like properties

Synthesis and antiproliferative activity of 7-azaindirubin-3'-oxime, a 7-aza isostere of the natural indirubin pharmacophore.

The RAF family: an expanding network of post-translational controls and protein-protein interactions.

The discovery and characterization of an interleukin 6 cytokine family antagonist protein from a marine sponge, Callyspongia sp

The role of the C-terminal domain of protein tyrosine phosphatase-1B in phosphatase activity and substrate binding

Transmembrane orientation of proteins present in acetylcholine receptor-rich membranes from Torpedo marmorata studied by selective proteolysis