Lista de obras - Henriette Meyer zu Schwabedissen

CYP2D6 function moderates the pharmacokinetics and pharmacodynamics of 3,4-methylene-dioxymethamphetamine in a controlled study in healthy individuals

artículo científico publicado en 2016

Cell-specific expression of uptake transporters--a potential approach for cardiovascular drug delivery devices.

artículo científico publicado en 2014

Cellular export of drugs and signaling molecules by the ATP-binding cassette transporters MRP4 (ABCC4) and MRP5 (ABCC5).

artículo científico publicado en 2005

Characterization of OATP1B3 and OATP2B1 transporter expression in the islet of the adult human pancreas

artículo científico

Childhood Trauma and Functional Variants of 5-HTTLPR Are Independently Associated with Alexithymia in 5,283 Subjects from the General Population.

artículo científico publicado en 2018

Clinical relevance of St. John's wort drug interactions revisited

artículo científico publicado en 2020

Cohort profile: Greifswald approach to individualized medicine (GANI_MED)

artículo científico publicado en 2014

Compartment-Specific Gene Regulation of the CAR Inducer Efavirenz In Vivo ⬇️

artículo científico publicado el 16 de mayo de 2012

Creatine kinase elevation caused by a combination of fluvastatin and telmisartan in a patient heterozygous for the CYP2C9*3 and ABCC2 -24C > T variants: a case report

artículo científico publicado en 2014

Current understanding of hepatic and intestinal OATP-mediated drug-drug interactions.

artículo científico publicado en 2011

Design, Synthesis, and Characterization of a Paclitaxel Formulation Activated by Extracellular MMP9

artículo científico publicado en 2020

Direct mass spectrometric identification of ABCB1 (P-glycoprotein/MDR1) from the apical membrane fraction of human placenta using fourier transform ion cyclotron mass spectrometry.

artículo científico publicado en 2006

Doxorubicin enhances oxysterol levels resulting in a LXR-mediated upregulation of cardiac cholesterol transporters.

artículo científico

Effect of the interaction between childhood abuse and rs1360780 of the FKBP5 gene on gray matter volume in a general population sample

artículo científico publicado en 2016

Epidermal growth factor-mediated activation of the map kinase cascade results in altered expression and function of ABCG2 (BCRP).

artículo científico publicado en 2006

Establishment and validation of competitive counterflow as a method to detect substrates of the organic anion transporting polypeptide 2B1

artículo científico publicado en 2018

Expression and localization of P-glycoprotein in human heart: effects of cardiomyopathy.

artículo científico publicado en 2002

Expression of OATP2B1 as determinant of drug effects in the microcompartment of the coronary artery.

artículo científico publicado en 2015

Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular differentiation

artículo científico publicado en 2005

Expression, localization, and function of the carnitine transporter octn2 (slc22a5) in human placenta.

artículo científico publicado en 2004

Ezetimib

artículo científico publicado en 2004

Function-impairing polymorphisms of the hepatic uptake transporter SLCO1B1 modify the therapeutic efficacy of statins in a population-based cohort

artículo científico publicado en 2015

Functional assessment of genetic variants located in the promoter of SHP1 (NR0B2).

artículo científico publicado en 2017

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

artículo científico publicado en 2014

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

artículo científico publicado en 2017

Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians

article

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

artículo científico publicado en 2018

Heparin inhibits TNF- signaling in human endometrial stromal cells by interaction with NF- B

artículo científico publicado en 2012

Hepatic OATP1B transporters and nuclear receptors PXR and CAR: interplay, regulation of drug disposition genes, and single nucleotide polymorphisms.

artículo científico publicado en 2009

Hepatic organic anion transporting polypeptide transporter and thyroid hormone receptor interplay determines cholesterol and glucose homeostasis

artículo científico publicado en 2011

Hyperforin-Induced Activation of the Pregnane X Receptor Is Influenced by the Organic Anion-Transporting Polypeptide 2B1

artículo científico publicado en 2018

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease

artículo científico publicado en 2014

Implant-associated local drug delivery systems based on biodegradable polymers: customized designs for different medical applications

artículo científico publicado en 2013

In Vitro and In Vivo Assessment of Renal Drug Transporters in the Disposition of Mesna and Dimesna

artículo científico publicado en 2012

In Vitro and In Vivo Evidence for the Importance of Breast Cancer Resistance Protein Transporters (BCRP/MXR/ABCP/ABCG2) ⬇️

artículo científico publicado el 1 de enero de 2011

In vitro study of dual drug-eluting stents with locally focused sirolimus and atorvastatin release.

artículo científico publicado en 2013

Interaction among childhood trauma and functional polymorphisms in the serotonin pathway moderate the risk of depressive disorders

artículo científico publicado en 2014

Inverse association between serum free thyroxine levels and hepatic steatosis: results from the Study of Health in Pomerania

artículo científico publicado en 2012

LST-3TM12 is a member of the OATP1B family and a functional transporter.

artículo científico publicado en 2017

Liver X receptor α and farnesoid X receptor are major transcriptional regulators of OATP1B1.

artículo científico publicado en 2010

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

artículo científico publicado en 2011

Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function

artículo científico publicado en 2012

Modulation of expression of the nuclear receptor NR0B2 (small heterodimer partner 1) and its impact on proliferation of renal carcinoma cells

artículo científico publicado en 2016

Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms

artículo científico publicado en 2004

No major role of norepinephrine transporter gene variations in the cardiostimulant effects of MDMA.

artículo científico publicado en 2017

Nonresponse to high-dose bupropion for depression in a patient carrying CYP2B66 and CYP2C1917 variants: a case report

scientific article published on 30 October 2020

OATP1A2 and OATP2B1 Are Interacting with Dopamine-Receptor Agonists and Antagonists

artículo científico publicado en 2020

OATP1B3 is expressed in pancreatic β-islet cells and enhances the insulinotropic effect of the sulfonylurea derivative glibenclamide

artículo científico publicado en 2013

Optimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptide

scientific article published on 23 July 2019

Organic anion transporting polypeptide 2B1 and breast cancer resistance protein interact in the transepithelial transport of steroid sulfates in human placenta.

artículo científico publicado en 2006

PDZ domain containing protein 1 (PDZK1), a modulator of membrane proteins, is regulated by the nuclear receptor THRβ.

artículo científico publicado en 2017

Personalized cardiovascular medicine: concepts and methodological considerations.

artículo científico

Pharmacogenetics of ecstasy: CYP1A2, CYP2C19, and CYP2B6 polymorphisms moderate pharmacokinetics of MDMA in healthy subjects.

artículo científico publicado en 2017

Pharmacokinetics of oxycodone/naloxone and its metabolites in patients with end-stage renal disease during and between haemodialysis sessions

artículo científico publicado en 2019

Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival.

artículo científico publicado en 2014

Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variability

artículo científico publicado en 2010

Population pharmacokinetics of oral ivermectin in venous plasma and dried blood spots in healthy volunteers

artículo científico publicado en 2019

Positive association of serum prolactin concentrations with all-cause and cardiovascular mortality

article

Regulation of PDZ domain-containing 1 (PDZK1) expression by hepatocyte nuclear factor-1α (HNF1α) in human kidney

artículo científico publicado en 2017

Role of Serotonin Transporter and Receptor Gene Variations in the Acute Effects of MDMA in Healthy Subjects

artículo científico publicado en 2019

Secreted Matrix Metalloproteinase-9 of Proliferating Smooth Muscle Cells as a Trigger for Drug Release from Stent Surface Polymers in Coronary Arteries

artículo científico publicado en 2016

Sepsis affects cardiac expression of multidrug resistance protein 5 (MRP5, ABCC5), an ABC-type CGMP export pump

artículo científico publicado en 2007

SwissPK<sup>cdw</sup> - A clinical data warehouse for the optimization of pediatric dosing regimens

artículo científico publicado en 2021

Synthesis and characterization of a PDMS-PMOXA based polymersomes sensitive to MMP-9 for application in breast cancer

artículo científico publicado en 2018

Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin

artículo científico publicado en 2008

The ATP-binding cassette transporter ABCG2 (BCRP), a marker for side population stem cells, is expressed in human heart.

artículo científico publicado en 2005

The effect of catechol-O-methyltransferase polymorphisms on pain is modified by depressive symptoms

artículo científico publicado en 2011

Transcriptional regulation of urate transportosome member SLC2A9 by nuclear receptor HNF4α

artículo científico publicado en 2014

UDP glucuronosyltransferase 2B7 single nucleotide polymorphism (rs7439366) influences heat pain response in human volunteers after i.v. morphine infusion.

artículo científico publicado en 2011

Variable expression of MRP2 (ABCC2) in human placenta: influence of gestational age and cellular differentiation.

artículo científico publicado en 2005

Variants of Toll-like receptor 4 predict cardiac recovery in patients with dilated cardiomyopathy.

artículo científico publicado en 2012

Lista de obras de Henriette Meyer zu Schwabedissen

CYP2D6 function moderates the pharmacokinetics and pharmacodynamics of 3,4-methylene-dioxymethamphetamine in a controlled study in healthy individuals

Cell-specific expression of uptake transporters--a potential approach for cardiovascular drug delivery devices.

Cellular export of drugs and signaling molecules by the ATP-binding cassette transporters MRP4 (ABCC4) and MRP5 (ABCC5).

Characterization of OATP1B3 and OATP2B1 transporter expression in the islet of the adult human pancreas

Childhood Trauma and Functional Variants of 5-HTTLPR Are Independently Associated with Alexithymia in 5,283 Subjects from the General Population.

Clinical relevance of St. John's wort drug interactions revisited

Cohort profile: Greifswald approach to individualized medicine (GANI_MED)

Compartment-Specific Gene Regulation of the CAR Inducer Efavirenz In Vivo ⬇️

Creatine kinase elevation caused by a combination of fluvastatin and telmisartan in a patient heterozygous for the CYP2C9*3 and ABCC2 -24C > T variants: a case report

Current understanding of hepatic and intestinal OATP-mediated drug-drug interactions.

Design, Synthesis, and Characterization of a Paclitaxel Formulation Activated by Extracellular MMP9

Direct mass spectrometric identification of ABCB1 (P-glycoprotein/MDR1) from the apical membrane fraction of human placenta using fourier transform ion cyclotron mass spectrometry.

Doxorubicin enhances oxysterol levels resulting in a LXR-mediated upregulation of cardiac cholesterol transporters.

Effect of the interaction between childhood abuse and rs1360780 of the FKBP5 gene on gray matter volume in a general population sample

Epidermal growth factor-mediated activation of the map kinase cascade results in altered expression and function of ABCG2 (BCRP).

Establishment and validation of competitive counterflow as a method to detect substrates of the organic anion transporting polypeptide 2B1

Expression and localization of P-glycoprotein in human heart: effects of cardiomyopathy.

Expression of OATP2B1 as determinant of drug effects in the microcompartment of the coronary artery.

Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular differentiation

Expression, localization, and function of the carnitine transporter octn2 (slc22a5) in human placenta.

Ezetimib

Function-impairing polymorphisms of the hepatic uptake transporter SLCO1B1 modify the therapeutic efficacy of statins in a population-based cohort

Functional assessment of genetic variants located in the promoter of SHP1 (NR0B2).

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

Heparin inhibits TNF- signaling in human endometrial stromal cells by interaction with NF- B

Hepatic OATP1B transporters and nuclear receptors PXR and CAR: interplay, regulation of drug disposition genes, and single nucleotide polymorphisms.

Hepatic organic anion transporting polypeptide transporter and thyroid hormone receptor interplay determines cholesterol and glucose homeostasis

Hyperforin-Induced Activation of the Pregnane X Receptor Is Influenced by the Organic Anion-Transporting Polypeptide 2B1

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease

Implant-associated local drug delivery systems based on biodegradable polymers: customized designs for different medical applications

In Vitro and In Vivo Assessment of Renal Drug Transporters in the Disposition of Mesna and Dimesna

In Vitro and In Vivo Evidence for the Importance of Breast Cancer Resistance Protein Transporters (BCRP/MXR/ABCP/ABCG2) ⬇️

In vitro study of dual drug-eluting stents with locally focused sirolimus and atorvastatin release.

Interaction among childhood trauma and functional polymorphisms in the serotonin pathway moderate the risk of depressive disorders

Inverse association between serum free thyroxine levels and hepatic steatosis: results from the Study of Health in Pomerania

LST-3TM12 is a member of the OATP1B family and a functional transporter.

Liver X receptor α and farnesoid X receptor are major transcriptional regulators of OATP1B1.

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function

Modulation of expression of the nuclear receptor NR0B2 (small heterodimer partner 1) and its impact on proliferation of renal carcinoma cells

Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms

No major role of norepinephrine transporter gene variations in the cardiostimulant effects of MDMA.

Nonresponse to high-dose bupropion for depression in a patient carrying CYP2B6*6 and CYP2C19*17 variants: a case report

OATP1A2 and OATP2B1 Are Interacting with Dopamine-Receptor Agonists and Antagonists

OATP1B3 is expressed in pancreatic β-islet cells and enhances the insulinotropic effect of the sulfonylurea derivative glibenclamide

Optimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptide

Organic anion transporting polypeptide 2B1 and breast cancer resistance protein interact in the transepithelial transport of steroid sulfates in human placenta.

PDZ domain containing protein 1 (PDZK1), a modulator of membrane proteins, is regulated by the nuclear receptor THRβ.

Personalized cardiovascular medicine: concepts and methodological considerations.

Pharmacogenetics of ecstasy: CYP1A2, CYP2C19, and CYP2B6 polymorphisms moderate pharmacokinetics of MDMA in healthy subjects.

Pharmacokinetics of oxycodone/naloxone and its metabolites in patients with end-stage renal disease during and between haemodialysis sessions

Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival.

Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variability

Population pharmacokinetics of oral ivermectin in venous plasma and dried blood spots in healthy volunteers

Positive association of serum prolactin concentrations with all-cause and cardiovascular mortality

Regulation of PDZ domain-containing 1 (PDZK1) expression by hepatocyte nuclear factor-1α (HNF1α) in human kidney

Role of Serotonin Transporter and Receptor Gene Variations in the Acute Effects of MDMA in Healthy Subjects

Secreted Matrix Metalloproteinase-9 of Proliferating Smooth Muscle Cells as a Trigger for Drug Release from Stent Surface Polymers in Coronary Arteries

Sepsis affects cardiac expression of multidrug resistance protein 5 (MRP5, ABCC5), an ABC-type CGMP export pump

SwissPK<sup>cdw</sup> - A clinical data warehouse for the optimization of pediatric dosing regimens

Synthesis and characterization of a PDMS-PMOXA based polymersomes sensitive to MMP-9 for application in breast cancer

Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin

The ATP-binding cassette transporter ABCG2 (BCRP), a marker for side population stem cells, is expressed in human heart.

The effect of catechol-O-methyltransferase polymorphisms on pain is modified by depressive symptoms

Transcriptional regulation of urate transportosome member SLC2A9 by nuclear receptor HNF4α

UDP glucuronosyltransferase 2B7 single nucleotide polymorphism (rs7439366) influences heat pain response in human volunteers after i.v. morphine infusion.

Variable expression of MRP2 (ABCC2) in human placenta: influence of gestational age and cellular differentiation.

Variants of Toll-like receptor 4 predict cardiac recovery in patients with dilated cardiomyopathy.

Nonresponse to high-dose bupropion for depression in a patient carrying CYP2B66 and CYP2C1917 variants: a case report