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Lista de obras de Trevor Owens

A noncognate interaction with anti-receptor antibody-activated helper T cells induces small resting murine B cells to proliferate and to secrete antibody

artículo científico publicado en 1988

A novel microglial subset plays a key role in myelinogenesis in developing brain

artículo científico publicado en 2017

A pathogenic role for CD8+ T cells in a spontaneous model of demyelinating disease

scientific article published on 01 August 2006

A role for adhesion molecules in contact-dependent T help for B cells

artículo científico publicado el 1 de abril de 1991

A specific and sensitive method for visualization of tumor necrosis factor in the murine central nervous system

artículo científico publicado en 2001

A wonderful week of immunology in Copenhagen

artículo científico publicado en 2013

An allospecific murine T helper clone which can help both T and B cell responses in vitro and in vivo

artículo científico publicado en 1984

Angiotensin AT2 receptor-induced interleukin-10 attenuates neuromyelitis optica spectrum disorder-like pathology

scientific article published on 09 July 2019

Angiotensin II Type 1 receptor (AT1) signaling in astrocytes regulates synaptic degeneration-induced leukocyte entry to the central nervous system.

artículo científico publicado en 2010

Animal models for multiple sclerosis.

artículo científico publicado en 2006

Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis

artículo científico publicado en 1997

Astrogliosis in the neonatal and adult murine brain post-trauma: elevation of inflammatory cytokines and the lack of requirement for endogenous interferon-gamma

artículo científico publicado en 1997

Axotomy-induced glial reactions in normal and cytokine transgenic mice.

artículo científico publicado en 1999

Blood-brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation

artículo científico publicado en 2012

Bone marrow-derived versus parenchymal sources of inducible nitric oxide synthase in experimental autoimmune encephalomyelitis.

artículo científico publicado en 2004

CCL2 recruits T cells into the brain in a CCR2-independent manner.

artículo científico publicado en 2017

CD8+ T cells in inflammatory demyelinating disease.

artículo científico publicado en 2007

CD95–CD95L: can the brain learn from the immune system?

artículo científico publicado el 1 de marzo de 1998

CSF1R Stimulation Promotes Increased Neuroprotection by CD11c+ Microglia in EAE

artículo científico publicado en 2018

Cell interactions in concanavalin A activated cation flux and DNA synthesis of mouse lymphocytes

artículo científico publicado en 1980

Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier.

artículo científico publicado en 2015

Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS.

artículo científico publicado en 2003

Chemokine expression in GKO mice (lacking interferon-gamma) with experimental autoimmune encephalomyelitis

artículo científico publicado en 1999

Chemokine receptor expression by inflammatory T cells in EAE.

artículo científico publicado en 2014

Chemokines in experimental autoimmune encephalomyelitis and multiple sclerosis.

artículo científico publicado en 2003

Co-stimulation by anti-immunoglobulin is required for B cell activation by CD40Llow T cells

scientific article published on 01 December 1994

Comparison of microglia and infiltrating CD11c⁺ cells as antigen presenting cells for T cell proliferation and cytokine response.

artículo científico publicado en 2014

Complement-dependent pathogenicity of brain-specific antibodies in cerebrospinal fluid.

artículo científico publicado en 2012

Constitutive activation of extracellular signal-regulated kinase predisposes diffuse large B-cell lymphoma cell lines to CD40-mediated cell death

artículo científico publicado en 2006

Continued administration of ciliary neurotrophic factor protects mice from inflammatory pathology in experimental autoimmune encephalomyelitis.

artículo científico publicado en 2006

Cytokine and chemokine inter-regulation in the inflamed or injured CNS

scientific article published on 12 January 2005

Cytokine production by cells in cerebrospinal fluid during experimental allergic encephalomyelitis in SJL/J mice

artículo científico publicado en 1994

DNA strand breaks and differentiation

artículo científico publicado en 1983

Derivation from an alloreactive T-cell line of a clone which cross-reacts with a self H2-E-restricted minor alloantigen

artículo científico publicado en 1984

Detection and cellular localization of phospho-STAT2 in the central nervous system by immunohistochemical staining.

artículo científico publicado en 2013

Detection of colony-stimulating factor messenger RNA in single T cells by in situ hybridization

artículo científico publicado en 1989

Diffusion Kurtosis Imaging maps neural damage in the EAE model of multiple sclerosis

scientific article published on 10 December 2019

Direct demonstration of the infiltration of murine central nervous system by Pgp-1/CD44high CD45RB(low) CD4+ T cells that induce experimental allergic encephalomyelitis

artículo científico publicado en 1992

Dynamics of oligodendrocyte responses to anterograde axonal (Wallerian) and terminal degeneration in normal and TNF-transgenic mice

artículo científico publicado en 2004

Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties

artículo científico publicado en 2017

Elevated interferon gamma expression in the central nervous system of tumour necrosis factor receptor 1-deficient mice with experimental autoimmune encephalomyelitis.

artículo científico publicado en 2006

Elevated interferon-gamma in CNS inflammatory disease: a potential complication for bone marrow reconstitution in MS

artículo científico publicado en 2000

Enhanced microglial clearance of myelin debris in T cell-infiltrated central nervous system

artículo científico publicado en 2009

Enhanced response to antigen within lymph nodes of SJL/J mice that were protected against experimental allergic encephalomyelitis by T cell vaccination

artículo científico publicado en 1993

Experimental Demyelination and Axonal Loss Are Reduced in MicroRNA-146a Deficient Mice

artículo científico publicado en 2018

Expression of astrocytic type 2 angiotensin receptor in central nervous system inflammation correlates with blood-brain barrier breakdown

artículo científico publicado en 2010

Glutamate metabolism is down-regulated in astrocytes during experimental allergic encephalomyelitis

artículo científico publicado en 1997

Helper T cell lines to major and to minor histocompatibility antigens are equally effective in the regulation of B cell responses in vivo.

artículo científico publicado en 1984

Hypersensitivity Responses in the Central Nervous System

artículo científico publicado en 2015

IFN-gamma enhances neurogenesis in wild-type mice and in a mouse model of Alzheimer's disease

artículo científico publicado en 2008

IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines.

artículo científico publicado en 2000

IFN-gamma-induced chemokines synergize with pertussis toxin to promote T cell entry to the central nervous system.

artículo científico publicado en 2007

IFNgamma enhances microglial reactions to hippocampal axonal degeneration

artículo científico publicado en 2000

Immune cell entry to the CNS--a focus for immunoregulation of EAE

article

Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice

artículo científico publicado en 1998

Immune regulation and CNS autoimmune disease.

artículo científico publicado en 1999

Immunotherapy for multiple sclerosis: from theory to practice

scientific article published on 01 October 1996

In vivo and in vitro requirements for T-cell activation: Concordance and contrasts

artículo científico publicado el 1 de noviembre de 1984

Increased cationic fluxes in stimulated lymphocytes of the mouse: response of enriched B- and T-cell subpopulations to B- and T-cell mitogens

scientific article published on 01 October 1980

Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor-alpha in the central nervous system

artículo científico publicado en 1997

Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis.

artículo científico publicado en 2015

Inflammation in the central nervous system and Th17 responses are inhibited by IFN-gamma-Induced IL-18 binding protein.

artículo científico publicado en 2010

Influence of type I IFN signaling on anti-MOG antibody-mediated demyelination.

artículo científico publicado en 2017

Inhibition of reactive astrocytosis in established experimental autoimmune encephalomyelitis favors infiltration by myeloid cells over T cells and enhances severity of disease.

artículo científico publicado en 2011

Injury-induced type I IFN signaling regulates inflammatory responses in the central nervous system

artículo científico publicado en 2010

Innate immune responses in central nervous system inflammation

artículo científico publicado el 27 de mayo de 2011

Innate signaling within the central nervous system recruits protective neutrophils

scientific article published on 08 January 2020

Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice.

artículo científico publicado en 2011

Interferon-gamma confers resistance to experimental allergic encephalomyelitis.

artículo científico publicado en 1996

Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE

artículo científico publicado en 1998

Interferons in the central nervous system: a few instruments play many tunes.

artículo científico

Key metalloproteinases are expressed by specific cell types in experimental autoimmune encephalomyelitis

article

Loss rather than downregulation of CD4+ T cells as a mechanism for remission from experimental allergic encephalomyelitis

artículo científico publicado en 1993

MOG extracellular domain (p1-125) triggers elevated frequency of CXCR3+ CD4+ Th1 cells in the CNS of mice and induces greater incidence of severe EAE

artículo científico publicado en 2014

Metalloproteinases control brain inflammation induced by pertussis toxin in mice overexpressing the chemokine CCL2 in the central nervous system

artículo científico publicado en 2006

Microglia and macrophages express tumor necrosis factor receptor p75 following middle cerebral artery occlusion in mice

artículo científico publicado en 2006

Microglia are required for astroglial Toll-like receptor 4 response and for optimal TLR2 and TLR3 response.

artículo científico publicado en 2012

Multiple sclerosis and immune regulatory cells

artículo científico publicado en 2004

NF-kappaB-driven STAT2 and CCL2 expression in astrocytes in response to brain injury

artículo científico publicado en 2008

Neuromyelitis optica (NMO)--an autoimmune disease of the central nervous system (CNS).

artículo científico publicado en 2010

Neuromyelitis optica-like pathology is dependent on type I interferon response.

artículo científico publicado en 2013

Neutrophils that infiltrate the central nervous system regulate T cell responses

article

Nogo-A is a reliable oligodendroglial marker in adult human and mouse CNS and in demyelinated lesions

artículo científico publicado en 2007

PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis

artículo científico publicado en 1997

Participation of L3T4 in T cell activation in the absence of class II major histocompatibility complex antigens. Inhibition by anti-L3T4 antibodies is a function both of epitope density and mode of presentation of anti-receptor antibody

artículo científico publicado en 1987

Pathologic and Protective Roles for Microglial Subsets and Bone Marrow- and Blood-Derived Myeloid Cells in Central Nervous System Inflammation

artículo científico publicado en 2015

Peripheral phosphodiesterase 4 inhibition produced by 4-[2-(3,4-Bis-difluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) prevents experimental autoimmune encephalomyelitis

artículo científico publicado en 2006

Production of two hemopoietic growth factors is differentially regulated in single T lymphocytes activated with an anti-T cell receptor antibody

artículo científico publicado en 1988

Proliferating resident microglia express the stem cell antigen CD34 in response to acute neural injury

artículo científico publicado en 2005

Protective roles for myeloid cells in neuroinflammation

artículo científico publicado en 2020

Reactive microgliosis engages distinct responses by microglial subpopulations after minor central nervous system injury

artículo científico publicado en 2005

Requirement for noncognate interaction with T cells for the activation of B cell immunoglobulin secretion by IL-2

artículo científico publicado el 1 de abril de 1991

Selective enrichment of Th1 CD45RBlow CD4+ T cells in autoimmune infiltrates in experimental allergic encephalomyelitis

scientific article published on 01 March 1994

Selective localization of IgG from cerebrospinal fluid to brain parenchyma.

artículo científico publicado en 2018

Signaling through MyD88 regulates leukocyte recruitment after brain injury.

artículo científico publicado en 2008

Signaling through intercellular adhesion molecule 1 (ICAM-1) in a B cell lymphoma line. The activation of Lyn tyrosine kinase and the mitogen-activated protein kinase pathway

artículo científico publicado en 1997

Specific blockade by CD54 and MHC II of CD40-mediated signaling for B cell proliferation and survival

artículo científico publicado en 2001

Statin therapy inhibits remyelination in the central nervous system.

artículo científico publicado en 2009

Stimulation of adult oligodendrogenesis by myelin-specific T cells

artículo científico publicado en 2011

Suppression induction in vivo by a T helper clone?

artículo científico publicado en 1985

Suppressor T cells, distinct from "veto cells," are induced by alloantigen priming and mediate transferable suppression of cytotoxic T lymphocyte responses in vivo

artículo científico publicado en 1985

Surfactant protein d deficiency in mice is associated with hyperphagia, altered fat deposition, insulin resistance, and increased basal endotoxemia

artículo científico publicado en 2012

T cell antigen receptor expression by subsets of Ly-2-L3T4- (CD8-CD4-) thymocytes

artículo científico publicado en 1988

T-cell costimulation: T cells themselves call the shots.

artículo científico publicado en 1996

T-dependent B-cell activation is signalled by an early increase in potassium influx.

artículo científico publicado en 1982

TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice

artículo científico publicado en 2012

TNF-alpha expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines

artículo científico publicado en 1995

TNFalpha: kill or cure for demyelinating disease?

artículo científico publicado en 2002

Th1 and Th2 help for B cells: differential capacity for induction of autonomous responsiveness to IL-2

artículo científico publicado en 1995

The Presentation of Cell Surface Alloantigens to T Cells

artículo científico publicado el 1 de diciembre de 1984

The acquisition of cytokine responsiveness by murine B cells: a role for antigen and IL-5 in the induction of IL-2 receptors

scientific article published on 01 March 1994

The attraction of adhesion molecules

scientific article published on 01 August 1993

The cation pump as a switch mechanism controlling proliferation and differentiation in lymphocytes

artículo científico publicado en 1982

The cell biology of T-dependent B cell activation.

artículo científico publicado en 1989

The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis

artículo científico publicado el 1 de noviembre de 1997

The changing face of cytokines in the brain: perspectives from EAE.

artículo científico publicado en 2005

The chemokine receptor CCR2 maintains plasmacytoid dendritic cell homeostasis

artículo científico publicado en 2017

The complex immunology of multiple sclerosis

artículo científico publicado en 2014

The effect of ultraviolet radiation on early stages of activation of human lymphocytes: inhibition is independent of effects on DNA

scientific article published on 01 September 1982

The murine gammaherpesvirus-68 chemokine-binding protein M3 inhibits experimental autoimmune encephalomyelitis

artículo científico publicado en 2010

The role of CD4 in antigen-independent activation of isolated single T lymphocytes

artículo científico publicado en 1988

Thymic CCL2 influences induction of T-cell tolerance

artículo científico publicado en 2014

Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation.

artículo científico publicado en 2006

Toll-like receptors in brain development and homeostasis.

artículo científico publicado en 2007

Toll-like receptors in neurodegeneration.

scientific article published on January 2009

Toll-like receptors on astrocytes: patterning for immunity

artículo científico publicado en 2004

Type I interferon-activated microglia are critical for neuromyelitis optica pathology

artículo científico publicado en 2020

VIth International Congress of Neuroimmunology. Edinburgh, Scotland, September 3-7, 2001.

artículo científico publicado en 2002

Vav-1 expression correlates with NFκB activation and CD40-mediated cell death in diffuse large B-cell lymphoma cell lines

artículo científico publicado en 2010

Veto in vivo?

artículo científico publicado en 1985

What is microglia neurotoxicity (Not)?

artículo científico publicado en 2014

X-linked inhibitor of apoptosis regulates T cell effector function

article

[MBP P89-101 induced experimental allergic encephalomyelitis in mice and establishment of CD4+ T cell line specific to MBP P89-101]

scientific article published on 01 June 1994