Lista de obras - Owen L Woodman - Dominio Público Uruguay

2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition

artículo científico publicado en 2012

3', 4'-dihydroxyflavonol enhances nitric oxide bioavailability and improves vascular function after ischemia and reperfusion injury in the rat.

artículo científico publicado en 2003

3',4'-Dihydroxyflavonol reduces infarct size and injury associated with myocardial ischaemia and reperfusion in sheep.

artículo científico publicado en 2004

3',4'-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries.

artículo científico publicado en 2011

3',4'-Dihydroxyflavonol restores endothelium-dependent relaxation in small mesenteric artery from rats with type 1 and type 2 diabetes

scientific article published on 29 March 2011

3',4'-dihydroxyflavonol ameliorates endoplasmic reticulum stress-induced apoptosis and endothelial dysfunction in mice

artículo científico publicado en 2018

3′,4′-Dihydroxyflavonol Antioxidant Attenuates Diastolic Dysfunction and Cardiac Remodeling in Streptozotocin-Induced Diabetic m(Ren2)27 Rats ⬇️

artículo científico publicado el 28 de julio de 2011

3′,4′-Dihydroxyflavonol reduces vascular contraction through Ca2+ desensitization in permeabilized rat mesenteric artery

scientific article published on 14 October 2011

A Functional Kinase Short Interfering Ribonucleic Acid Screen Using Protease-Activated Receptor 2-Dependent Opening of Transient Receptor Potential Vanilloid-4.

artículo científico publicado en 2017

Agonistic actions of DPI (2-(3,4-dihydroxyphenylimino)-imidazolidine) on α-adrenoceptors and dopamine receptors ⬇️

artículo científico publicado el 15 de octubre de 1981

Allopurinol and amlodipine improve coronary vasodilatation after myocardial ischaemia and reperfusion in anaesthetized dogs.

artículo científico publicado en 1993

Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening.

artículo científico publicado en 2010

Angiotensin II Causes β-Cell Dysfunction Through an ER Stress-Induced Proinflammatory Response.

artículo científico publicado en 2017

Annexin-1 peptide Anx-1(2-26) protects adult rat cardiac myocytes from cellular injury induced by simulated ischaemia.

artículo científico publicado en 2005

Antioxidant actions contribute to the antihypertrophic effects of atrial natriuretic peptide in neonatal rat cardiomyocytes

artículo científico publicado en 2006

Antioxidant activity contributes to flavonol cardioprotection during reperfusion of rat hearts ⬇️

artículo científico publicado el 18 de julio de 2011

Antioxidants in the prevention of myocardial ischemia/reperfusion injury

artículo científico publicado en 2009

Atrial natriuretic peptide prevents diabetes-induced endothelial dysfunction.

artículo científico publicado en 2008

Cardioprotection from ischaemia-reperfusion injury by a novel flavonol that reduces activation of p38 MAPK.

artículo científico publicado en 2011

Cardioprotective 3',4'-dihydroxyflavonol attenuation of JNK and p38(MAPK) signalling involves CaMKII inhibition.

artículo científico publicado en 2013

Cardioprotective potential of annexin-A1 mimetics in myocardial infarction

artículo científico publicado en 2014

Cardiovascular responses produced by the injection of dopamine into the cerebral ventricles of the unanaesthetized dog ⬇️

artículo científico publicado el 1 de junio de 1979

Chronic NaHS treatment decreases oxidative stress and improves endothelial function in diabetic mice

artículo científico publicado en 2017

Chronic treatment of male rats with daidzein and 17 beta-oestradiol induces the contribution of EDHF to endothelium-dependent relaxation.

artículo científico publicado en 2003

Comprehensive two-dimensional gas chromatography, retention indices and time-of-flight mass spectra of flavonoids and chalcones

artículo científico publicado en 2010

Coronary vascular responses to nicotine in the anaesthetized dog ⬇️

artículo científico publicado el 1 de enero de 1991

Discovery of water-soluble antioxidant flavonols without vasorelaxant activity

artículo científico publicado en 2008

Effect of ischaemic preconditioning on vascular dysfunction induced by ischaemia and reperfusion in rat hindquarters

scientific article published on 01 December 1996

Effect of type 1 diabetes on the production and vasoactivity of hydrogen sulfide in rat middle cerebral arteries

artículo científico publicado en 2013

Effects of 3',4'-dihydroxyflavonol on vascular contractions of rat aortic rings

artículo científico publicado en 2010

Effects of resveratrol and flavonols on cardiovascular function: Physiological mechanisms.

artículo científico publicado en 2010

Endothelium-dependent nitroxyl-mediated relaxation is resistant to superoxide anion scavenging and preserved in diabetic rat aorta

scientific article published on 09 August 2012

Enhanced role for the opening of potassium channels in relaxant responses to acetylcholine after myocardial ischaemia and reperfusion in dog coronary arteries.

artículo científico publicado en 1999

Enhanced vasoconstriction by serotonin in rabbit carotid arteries with atheroma-like lesions in vivo

scientific article published on 01 May 1991

Evidence that the MEK/ERK but not the PI3K/Akt pathway is required for protection from myocardial ischemia-reperfusion injury by 3',4'-dihydroxyflavonol.

artículo científico publicado en 2015

Flavonols in the Prevention of Diabetes-induced Vascular Dysfunction

artículo científico publicado en 2015

High-fructose diet elevates myocardial superoxide generation in mice in the absence of cardiac hypertrophy

artículo científico publicado en 2009

Impaired endothelium-dependent relaxation of dog coronary arteries after myocardial ischaemia and reperfusion: prevention by amlodipine, propranolol and allopurinol ⬇️

artículo científico publicado el 1 de marzo de 1992

Impaired vasodilator function of nitric oxide associated with developing neo-intima in conscious rabbits.

artículo científico publicado en 1994

Increased nitric oxide activity compensates for increased oxidative stress to maintain endothelial function in rat aorta in early type 1 diabetes

artículo científico publicado en 2012

Influence of type-4 dipeptidyl peptidase inhibition on endothelium-dependent relaxation of aortae from a db/db mouse model of type 2 diabetes: a comparison with the effect of glimepiride

scientific article published on 16 August 2019

Inhibition of nitric oxide synthase specifically enhances adrenergic vasoconstriction in rabbits

artículo científico publicado el 1 de julio de 1992

Inhibition of platelet-mediated arterial thrombosis and platelet granule exocytosis by 3',4'-dihydroxyflavonol and quercetin.

artículo científico publicado en 2012

Involvement of dopamine in control of renal blood flow

scientific article published on 01 November 1992

Involvement of nitric oxide in coronary vascular responses to 5-hydroxytryptamine in the anaesthetized greyhound

artículo científico publicado en 1994

Ischaemia enhances the role of Ca2+-activated K+ channels in endothelium-dependent and nitric oxide-mediated dilatation of the rat hindquarters vasculature.

artículo científico publicado en 2004

Isoflavones, equol and cardiovascular disease: pharmacological and therapeutic insights.

artículo científico publicado en 2007

Kinin receptors mediating the effects of bradykinin on the coronary circulation in anaesthetized greyhounds ⬇️

artículo científico publicado el 10 de abril de 1991

Low intrinsic exercise capacity in rats predisposes to age-dependent cardiac remodeling independent of macrovascular function.

artículo científico publicado en 2012

Microglia are selectively activated in endocrine and cardiovascular control centres in streptozotocin-induced diabetic rats.

artículo científico publicado en 2014

Modulation of vasoconstriction by endothelium-derived nitric oxide: the influence of vascular disease.

artículo científico publicado en 1995

Molecular Sensors of Blood Flow in Endothelial Cells

artículo científico publicado en 2017

New pharmacological approaches to the prevention of myocardial ischemia-reperfusion injury

artículo científico

Noradrenaline-induced constriction of large and small coronary arteries in the anaesthetized dog.

artículo científico publicado en 1989

Oestrogen and vasculoprotection.

artículo científico publicado en 2008

Pericardial release of prostacyclin induced by bradykinin and angiotensin II: effects on coronary blood flow in the dog

artículo científico publicado en 1983

Preconditioning improves myocardial function and reflow, but not vasodilator reactivity, after ischaemia and reperfusion in anaesthetized dogs ⬇️

artículo científico publicado el 1 de julio de 1998

Prevention of ischaemia-induced coronary vascular dysfunction.

artículo científico publicado en 1997

Prostacyclin produced by the pericardium and its influence on coronary vascular tone.

artículo científico publicado en 1983

Protection against reperfusion injury by 3',4'-dihydroxyflavonol in rat isolated hearts involves inhibition of phospholamban and JNK2.

artículo científico publicado en 2018

Rabbit mononuclear leukocytes cause contraction of isolated aorta by the release of serotonin

scientific article published on 01 January 1999

Reflex epicardial coronary vasoconstriction elicited by nicotine in anaesthetized dogs.

artículo científico publicado en 1989

Relaxation to flavones and flavonols in rat isolated thoracic aorta: mechanism of action and structure-activity relationships

artículo científico publicado en 2000

Shear stress sensitizes TRPV4 in endothelium-dependent vasodilatation

artículo científico publicado en 2018

Sodium nitroprusside protects adult rat cardiac myocytes from cellular injury induced by simulated ischemia: role for a non-cGMP-dependent mechanism of nitric oxide protection.

artículo científico publicado en 2006

Synthesis of a hypoxia-targeted conjugate of the cardioprotective agent 3′,4′-dihydroxyflavonol and evaluation of its ability to reduce ischaemia/reperfusion injury

artículo científico publicado en 2011

The DPP-4 inhibitor linagliptin and the GLP-1 receptor agonist exendin-4 improve endothelium-dependent relaxation of rat mesenteric arteries in the presence of high glucose

scientific article published on 16 February 2015

The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Preserves Endothelial Function in Mesenteric Arteries from Type 1 Diabetic Rats without Decreasing Plasma Glucose

artículo científico publicado en 2015

The HNO donor Angeli's salt offers potential haemodynamic advantages over NO or dobutamine in ischaemia-reperfusion injury in the rat heart ex vivo

artículo científico publicado en 2015

The cardioprotectant 3',4'-dihydroxyflavonol inhibits opening of the mitochondrial permeability transition pore after myocardial ischemia and reperfusion in rats

artículo científico publicado en 2014

The concomitant coronary vasodilator and positive inotropic actions of the nitroxyl donor Angeli's salt in the intact rat heart: contribution of soluble guanylyl cyclase-dependent and -independent mechanisms.

artículo científico publicado en 2014

The effect of hypercholesterolaemia and atherosclerosis on alpha-adrenoceptor-mediated vasoconstriction in conscious rabbits and rabbit aorta

artículo científico publicado en 1992

The ethanolic extract of Kaempferia parviflora reduces ischaemic injury in rat isolated hearts

scientific article published on 10 May 2011

The flavonols quercetin and 3',4'-dihydroxyflavonol reduce platelet function and delay thrombus formation in a model of type 1 diabetes

artículo científico publicado en 2014

The red wine antioxidant resveratrol prevents cardiomyocyte injury following ischemia-reperfusion via multiple sites and mechanisms.

artículo científico publicado en 2007

Tocotrienol Rich Palm Oil Extract Is More Effective Than Pure Tocotrienols at Improving Endothelium-Dependent Relaxation in the Presence of Oxidative Stress.

artículo científico publicado en 2015

Treatment with quercetin and 3',4'-dihydroxyflavonol inhibits platelet function and reduces thrombus formation in vivo

artículo científico publicado en 2013

Type 1 diabetes and hypercholesterolaemia reveal the contribution of endothelium-derived hyperpolarizing factor to endothelium-dependent relaxation of the rat aorta

artículo científico publicado en 2007

Understanding the cardioprotective effects of flavonols: discovery of relaxant flavonols without antioxidant activity

artículo científico publicado en 2008

Using behaviour to predict stroke severity in conscious rats: post-stroke treatment with 3', 4'-dihydroxyflavonol improves recovery.

artículo científico publicado en 2008

Vascular and anti-oxidant actions of flavonols and flavones.

artículo científico publicado en 2004

Vasoconstrictor responses to polymorphonuclear leucocytes from atherosclerotic rabbits

artículo científico publicado en 1994

Western Diet Chow Consumption in Rats Induces Striatal Neuronal Activation While Reducing Dopamine Levels without Affecting Spatial Memory in the Radial Arm Maze.

artículo científico publicado en 2017

Lista de obras de Owen L Woodman

2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition

3', 4'-dihydroxyflavonol enhances nitric oxide bioavailability and improves vascular function after ischemia and reperfusion injury in the rat.

3',4'-Dihydroxyflavonol reduces infarct size and injury associated with myocardial ischaemia and reperfusion in sheep.

3',4'-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries.

3',4'-Dihydroxyflavonol restores endothelium-dependent relaxation in small mesenteric artery from rats with type 1 and type 2 diabetes

3',4'-dihydroxyflavonol ameliorates endoplasmic reticulum stress-induced apoptosis and endothelial dysfunction in mice

3′,4′-Dihydroxyflavonol Antioxidant Attenuates Diastolic Dysfunction and Cardiac Remodeling in Streptozotocin-Induced Diabetic m(Ren2)27 Rats ⬇️

3′,4′-Dihydroxyflavonol reduces vascular contraction through Ca2+ desensitization in permeabilized rat mesenteric artery

A Functional Kinase Short Interfering Ribonucleic Acid Screen Using Protease-Activated Receptor 2-Dependent Opening of Transient Receptor Potential Vanilloid-4.

Agonistic actions of DPI (2-(3,4-dihydroxyphenylimino)-imidazolidine) on α-adrenoceptors and dopamine receptors ⬇️

Allopurinol and amlodipine improve coronary vasodilatation after myocardial ischaemia and reperfusion in anaesthetized dogs.

Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening.

Angiotensin II Causes β-Cell Dysfunction Through an ER Stress-Induced Proinflammatory Response.

Annexin-1 peptide Anx-1(2-26) protects adult rat cardiac myocytes from cellular injury induced by simulated ischaemia.

Antioxidant actions contribute to the antihypertrophic effects of atrial natriuretic peptide in neonatal rat cardiomyocytes

Antioxidant activity contributes to flavonol cardioprotection during reperfusion of rat hearts ⬇️

Antioxidants in the prevention of myocardial ischemia/reperfusion injury

Atrial natriuretic peptide prevents diabetes-induced endothelial dysfunction.

Cardioprotection from ischaemia-reperfusion injury by a novel flavonol that reduces activation of p38 MAPK.

Cardioprotective 3',4'-dihydroxyflavonol attenuation of JNK and p38(MAPK) signalling involves CaMKII inhibition.

Cardioprotective potential of annexin-A1 mimetics in myocardial infarction

Cardiovascular responses produced by the injection of dopamine into the cerebral ventricles of the unanaesthetized dog ⬇️

Chronic NaHS treatment decreases oxidative stress and improves endothelial function in diabetic mice

Chronic treatment of male rats with daidzein and 17 beta-oestradiol induces the contribution of EDHF to endothelium-dependent relaxation.

Comprehensive two-dimensional gas chromatography, retention indices and time-of-flight mass spectra of flavonoids and chalcones

Coronary vascular responses to nicotine in the anaesthetized dog ⬇️

Discovery of water-soluble antioxidant flavonols without vasorelaxant activity

Effect of ischaemic preconditioning on vascular dysfunction induced by ischaemia and reperfusion in rat hindquarters

Effect of type 1 diabetes on the production and vasoactivity of hydrogen sulfide in rat middle cerebral arteries

Effects of 3',4'-dihydroxyflavonol on vascular contractions of rat aortic rings

Effects of resveratrol and flavonols on cardiovascular function: Physiological mechanisms.

Endothelium-dependent nitroxyl-mediated relaxation is resistant to superoxide anion scavenging and preserved in diabetic rat aorta

Enhanced role for the opening of potassium channels in relaxant responses to acetylcholine after myocardial ischaemia and reperfusion in dog coronary arteries.

Enhanced vasoconstriction by serotonin in rabbit carotid arteries with atheroma-like lesions in vivo

Evidence that the MEK/ERK but not the PI3K/Akt pathway is required for protection from myocardial ischemia-reperfusion injury by 3',4'-dihydroxyflavonol.

Flavonols in the Prevention of Diabetes-induced Vascular Dysfunction

High-fructose diet elevates myocardial superoxide generation in mice in the absence of cardiac hypertrophy

Impaired endothelium-dependent relaxation of dog coronary arteries after myocardial ischaemia and reperfusion: prevention by amlodipine, propranolol and allopurinol ⬇️

Impaired vasodilator function of nitric oxide associated with developing neo-intima in conscious rabbits.

Increased nitric oxide activity compensates for increased oxidative stress to maintain endothelial function in rat aorta in early type 1 diabetes

Influence of type-4 dipeptidyl peptidase inhibition on endothelium-dependent relaxation of aortae from a db/db mouse model of type 2 diabetes: a comparison with the effect of glimepiride

Inhibition of nitric oxide synthase specifically enhances adrenergic vasoconstriction in rabbits

Inhibition of platelet-mediated arterial thrombosis and platelet granule exocytosis by 3',4'-dihydroxyflavonol and quercetin.

Involvement of dopamine in control of renal blood flow

Involvement of nitric oxide in coronary vascular responses to 5-hydroxytryptamine in the anaesthetized greyhound

Ischaemia enhances the role of Ca2+-activated K+ channels in endothelium-dependent and nitric oxide-mediated dilatation of the rat hindquarters vasculature.

Isoflavones, equol and cardiovascular disease: pharmacological and therapeutic insights.

Kinin receptors mediating the effects of bradykinin on the coronary circulation in anaesthetized greyhounds ⬇️

Low intrinsic exercise capacity in rats predisposes to age-dependent cardiac remodeling independent of macrovascular function.

Microglia are selectively activated in endocrine and cardiovascular control centres in streptozotocin-induced diabetic rats.

Modulation of vasoconstriction by endothelium-derived nitric oxide: the influence of vascular disease.

Molecular Sensors of Blood Flow in Endothelial Cells

New pharmacological approaches to the prevention of myocardial ischemia-reperfusion injury

Noradrenaline-induced constriction of large and small coronary arteries in the anaesthetized dog.

Oestrogen and vasculoprotection.

Pericardial release of prostacyclin induced by bradykinin and angiotensin II: effects on coronary blood flow in the dog

Preconditioning improves myocardial function and reflow, but not vasodilator reactivity, after ischaemia and reperfusion in anaesthetized dogs ⬇️

Prevention of ischaemia-induced coronary vascular dysfunction.

Prostacyclin produced by the pericardium and its influence on coronary vascular tone.

Protection against reperfusion injury by 3',4'-dihydroxyflavonol in rat isolated hearts involves inhibition of phospholamban and JNK2.

Rabbit mononuclear leukocytes cause contraction of isolated aorta by the release of serotonin

Reflex epicardial coronary vasoconstriction elicited by nicotine in anaesthetized dogs.

Relaxation to flavones and flavonols in rat isolated thoracic aorta: mechanism of action and structure-activity relationships

Shear stress sensitizes TRPV4 in endothelium-dependent vasodilatation

Sodium nitroprusside protects adult rat cardiac myocytes from cellular injury induced by simulated ischemia: role for a non-cGMP-dependent mechanism of nitric oxide protection.

Synthesis of a hypoxia-targeted conjugate of the cardioprotective agent 3′,4′-dihydroxyflavonol and evaluation of its ability to reduce ischaemia/reperfusion injury

The DPP-4 inhibitor linagliptin and the GLP-1 receptor agonist exendin-4 improve endothelium-dependent relaxation of rat mesenteric arteries in the presence of high glucose

The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Preserves Endothelial Function in Mesenteric Arteries from Type 1 Diabetic Rats without Decreasing Plasma Glucose

The HNO donor Angeli's salt offers potential haemodynamic advantages over NO or dobutamine in ischaemia-reperfusion injury in the rat heart ex vivo

The cardioprotectant 3',4'-dihydroxyflavonol inhibits opening of the mitochondrial permeability transition pore after myocardial ischemia and reperfusion in rats

The concomitant coronary vasodilator and positive inotropic actions of the nitroxyl donor Angeli's salt in the intact rat heart: contribution of soluble guanylyl cyclase-dependent and -independent mechanisms.

The effect of hypercholesterolaemia and atherosclerosis on alpha-adrenoceptor-mediated vasoconstriction in conscious rabbits and rabbit aorta

The ethanolic extract of Kaempferia parviflora reduces ischaemic injury in rat isolated hearts

The flavonols quercetin and 3',4'-dihydroxyflavonol reduce platelet function and delay thrombus formation in a model of type 1 diabetes

The red wine antioxidant resveratrol prevents cardiomyocyte injury following ischemia-reperfusion via multiple sites and mechanisms.

Tocotrienol Rich Palm Oil Extract Is More Effective Than Pure Tocotrienols at Improving Endothelium-Dependent Relaxation in the Presence of Oxidative Stress.

Treatment with quercetin and 3',4'-dihydroxyflavonol inhibits platelet function and reduces thrombus formation in vivo

Type 1 diabetes and hypercholesterolaemia reveal the contribution of endothelium-derived hyperpolarizing factor to endothelium-dependent relaxation of the rat aorta

Understanding the cardioprotective effects of flavonols: discovery of relaxant flavonols without antioxidant activity