Lista de obras - Jarmo T Laitinen - Dominio Público Uruguay

2,3,7,8-Tetrachlorodibenzo-p-dioxin alters melatonin metabolism in fish hepatocytes

scientific article published on 01 June 2000

A Sensitive and Versatile Fluorescent Activity Assay for ABHD12.

artículo científico publicado en 2016

A Sensitive and Versatile Fluorescent Activity Assay for ABHD6.

artículo científico publicado en 2016

A rhodopsin-based model for melatonin recognition at its G protein-coupled receptor

artículo científico publicado en 1996

A sensitive microassay reveals marked regional differences in the capacity of rat brain to generate carbon monoxide

artículo científico publicado en 1995

Adenosine A1 receptor-dependent G-protein activity in the rat brain during prolonged wakefulness.

artículo científico publicado en 2004

Age and adjustment to night work.

artículo científico publicado en 1994

An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A1 and cannabinoid CB1 receptors ⬇️

artículo científico publicado el 17 de noviembre de 2003

Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)

artículo científico publicado en 2012

Brain regional cannabinoid CB(1) receptor signalling and alternative enzymatic pathways for 2-arachidonoylglycerol generation in brain sections of diacylglycerol lipase deficient mice

artículo científico publicado en 2013

Characterization of melatonin receptors in the rat area postrema: modulation of affinity with cations and guanine nucleotides

artículo científico publicado en 1990

Characterization of melatonin receptors in the rat suprachiasmatic nuclei: modulation of affinity with cations and guanine nucleotides

artículo científico publicado en 1990

Characterization of the sulfhydryl-sensitive site in the enzyme responsible for hydrolysis of 2-arachidonoyl-glycerol in rat cerebellar membranes

artículo científico publicado en 2005

Chiral 1,3,4-oxadiazol-2-ones as highly selective FAAH inhibitors

artículo científico publicado en 2013

Circadian adjustment of men and women to night work

artículo científico publicado en 1996

Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes

artículo científico publicado en 2001

Different patterns of light exposure in relation to melatonin and cortisol rhythms and sleep of night workers

artículo científico publicado en 1994

Differential expression of melatonin receptors in spontaneously hypertensive rats

artículo científico publicado el 1 de diciembre de 1992

Differential regulation of the rat melatonin receptors: selective age-associated decline and lack of melatonin-induced changes

artículo científico publicado en 1992

Differential sensitivity to cations of the melatonin receptors in the rat area postrema and suprachiasmatic nuclei

artículo científico publicado en 1990

Discovery of 12-Thiazole Abietanes as Selective Inhibitors of the Human Metabolic Serine Hydrolase hABHD16A

artículo científico publicado en 2018

Discovery of triterpenoids as reversible inhibitors of α/β-hydrolase domain containing 12 (ABHD12)

artículo científico publicado en 2014

Diurnal rhythm of melatonin binding in the rat suprachiasmatic nucleus

artículo científico publicado en 1989

Diurnal rhythm of melatonin in bovine milk: pharmacokinetics of exogenous melatonin in lactating cows and goats

artículo científico publicado en 1998

Dopamine stimulates K+ efflux in the chick retina via D1 receptors independently of adenylyl cyclase activation.

artículo científico publicado en 1993

Effects of continuous opioid receptor blockade on alcohol intake and up-regulation of opioid receptor subtype signalling in a genetic model of high alcohol drinking.

artículo científico publicado en 1999

Effects of melatonin implants in spring on testicular regression and moulting in adult male raccoon dogs (Nyctereutes procynoides)

scientific article published on 01 September 1995

Effects of melatonin implants on winter fur growth and testicular recrudescence in adult male raccoon dogs (Nyctereutes procyonoides)

scientific article published on 01 April 1996

Effects of mobile phone radiation on UV-induced skin tumourigenesis in ornithine decarboxylase transgenic and non-transgenic mice.

artículo científico publicado en 2003

Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits.

artículo científico publicado en 2001

Exposure to a 50-hz magnetic field induces a circadian rhythm in 6-hydroxymelatonin sulfate excretion in mice.

artículo científico publicado en 2005

Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes

artículo científico publicado en 2014

Functional autoradiography shows unaltered cannabinoid CB1 receptor signalling in hippocampus and cortex of APP/PS1 transgenic mice

artículo científico publicado en 2012

Guanosine 5'-(gamma-[35S]thio)triphosphate autoradiography allows selective detection of histamine H3 receptor-dependent G protein activation in rat brain tissue sections.

artículo científico publicado en 1998

High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections - Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils

artículo científico publicado en 2020

Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptor

artículo científico publicado en 2005

Important amino acids for the function of the human MT1 melatonin receptor.

artículo científico publicado en 2003

In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048).

artículo científico publicado en 2016

Increased tonic cannabinoid CB1R activity and brain region-specific desensitization of CB1R Gi/o signaling axis in mice with global genetic knockout of monoacylglycerol lipase

artículo científico publicado en 2015

Intracerebroventricular antisense knockdown of G alpha i2 results in ciliary stasis and ventricular dilatation in the rat.

artículo científico publicado en 2007

Inverse agonist exposure enhances ligand binding and G protein activation of the human MT1 melatonin receptor, but leads to receptor down-regulation.

artículo científico publicado en 2007

Level and distribution of progesterone in bovine milk: effects of mastitis and milk composition

artículo científico publicado en 1986

Lipid phosphate phosphatase inhibitors locally amplify lysophosphatidic acid LPA1 receptor signalling in rat brain cryosections without affecting global LPA degradation

artículo científico publicado en 2012

Localization and variable expression of G alpha(i2) in human endometrium and Fallopian tubes.

artículo científico publicado en 2007

Long-term induction of haem oxygenase-1 (HSP-32) in astrocytes and microglia following transient focal brain ischaemia in the rat.

artículo científico publicado en 1996

Mechanism by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) reduces circulating melatonin levels in the rat.

artículo científico publicado en 1996

Melatonin receptor genes.

artículo científico publicado en 1998

Milk progesterone in Finnish dairy cows: a field study on the control of artificial insemination and early pregnancy

Monoglyceride lipase as an enzyme hydrolyzing 2-arachidonoylglycerol.

artículo científico publicado en 2007

Monoglyceride lipase-like enzymatic activity is responsible for hydrolysis of 2-arachidonoylglycerol in rat cerebellar membranes.

artículo científico publicado en 2004

Mutagenesis of human Mel1a melatonin receptor expressed in yeast reveals domains important for receptor function

artículo científico publicado en 1998

Neuroanatomical mapping of juvenile rat brain regions with prominent basal signal in [(35)S]GTPgammaS autoradiography.

artículo científico publicado en 2007

Oestrus and pregnancy diagnosis by milk progesterone assay in the mare

scientific article published on 01 September 1981

On the respective roles of nitric oxide and carbon monoxide in long-term potentiation in the hippocampus

artículo científico publicado en 1999

On the respective roles of nitric oxide and carbon monoxide in long-term potentiation in the hippocampus.

artículo científico publicado en 1998

Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau

artículo científico publicado en 2000

Pineal muscarinic phosphoinositide response: pertussis toxin resistant signaling with very low receptor number

artículo científico publicado en 1989

Pineal muscarinic phosphoinositide responses: age-associated sensitization, agonist-induced desensitization and increase in melatonin release from cultured pineal glands

artículo científico publicado en 1992

Potent and selective N-(4-sulfamoylphenyl)thiourea-based GPR55 agonists

artículo científico publicado en 2015

Protective properties of tin- and manganese-centered porphyrins against hydrogen peroxide-mediated injury in rat astroglial cells.

artículo científico publicado en 1998

Quantification of lysophosphatidic acids in rat brain tissue by liquid chromatography-electrospray tandem mass spectrometry

artículo científico publicado en 2010

Relation of age to circadian adjustment to night work

artículo científico publicado en 1992

Renal melatonin excretion in sheep is enhanced by water diuresis

scientific article published on 01 September 1993

Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors

artículo científico publicado en 2015

Selective detection of adenosine A1 receptor-dependent G-protein activity in basal and stimulated conditions of rat brain [35S]guanosine 5'-(gamma-thio)triphosphate autoradiography

artículo científico publicado en 1999

Synthesis and CB1 receptor activities of dimethylheptyl derivatives of 2-arachidonoyl glycerol (2-AG) and 2-arachidonyl glyceryl ether (2-AGE).

artículo científico publicado en 2006

Synthesis and SAR studies of 2-oxoquinoline derivatives as CB2 receptor inverse agonists.

artículo científico publicado en 2006

Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.

artículo científico publicado en 1999

Synthesis and preclinical evaluation of [11C]MA-PB-1 for in vivo imaging of brain monoacylglycerol lipase (MAGL).

artículo científico publicado en 2017

Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide.

artículo científico publicado en 2006

TCDD reduces serum melatonin levels in Long-Evans rats

artículo científico publicado en 1989

The 'allosteric modulator' SCH-202676 disrupts G protein-coupled receptor function via sulphydryl-sensitive mechanisms.

artículo científico publicado en 2006

The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D-lysophosphatidic acid receptor axis and 5-HT1A receptors in rat brain sections.

artículo científico publicado en 2006

The chick retinal melatonin receptor revisited: localization and modulation of agonist binding with guanine nucleotides

artículo científico publicado en 1990

The effect of four-day round trip flights over 10 time zones on the circadian variation of salivary melatonin and Cortisol in airline flight attendants

artículo científico publicado en 1994

The effect of photoperiod on diel rhythms in serum melatonin, cortisol, glucose, and electrolytes in the common dentex, Dentex dentex

scientific article published on 01 February 1999

The functional role of cysteines adjacent to the NRY motif of the human MT1 melatonin receptor.

artículo científico publicado en 2005

The prediction of the adaptation of circadian rhythms to rapid time zone changes

scientific article published on 01 January 1993

The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors

artículo científico publicado en 2012

Therapeutic potential of endocannabinoid-hydrolysing enzyme inhibitors.

artículo científico publicado en 2007

Virtual screening of novel CB2 ligands using a comparative model of the human cannabinoid CB2 receptor.

artículo científico publicado en 2005

Visualization of 2-arachidonoylglycerol accumulation and cannabinoid CB1 receptor activity in rat brain cryosections by functional autoradiography

artículo científico publicado en 2007

[(35)S]GTPgammaS autoradiography reveals a wide distribution of G(i/o)-linked ADP receptors in the nervous system: close similarities with the platelet P2Y(ADP) receptor.

artículo científico publicado en 2001

[Gamma-35S]GTP autoradiography allows region-specific detection of muscarinic receptor-dependent G-protein activation in the chick optic tectum

artículo científico publicado en 1997

[Physiology of the biological clock and the relation of circadian rhythm disorders to illnesses]

artículo científico publicado en 1999

Lista de obras de Jarmo T Laitinen

2,3,7,8-Tetrachlorodibenzo-p-dioxin alters melatonin metabolism in fish hepatocytes

A Sensitive and Versatile Fluorescent Activity Assay for ABHD12.

A Sensitive and Versatile Fluorescent Activity Assay for ABHD6.

A rhodopsin-based model for melatonin recognition at its G protein-coupled receptor

A sensitive microassay reveals marked regional differences in the capacity of rat brain to generate carbon monoxide

Adenosine A1 receptor-dependent G-protein activity in the rat brain during prolonged wakefulness.

Age and adjustment to night work.

An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A1 and cannabinoid CB1 receptors ⬇️

Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)

Brain regional cannabinoid CB(1) receptor signalling and alternative enzymatic pathways for 2-arachidonoylglycerol generation in brain sections of diacylglycerol lipase deficient mice

Characterization of melatonin receptors in the rat area postrema: modulation of affinity with cations and guanine nucleotides

Characterization of melatonin receptors in the rat suprachiasmatic nuclei: modulation of affinity with cations and guanine nucleotides

Characterization of the sulfhydryl-sensitive site in the enzyme responsible for hydrolysis of 2-arachidonoyl-glycerol in rat cerebellar membranes

Chiral 1,3,4-oxadiazol-2-ones as highly selective FAAH inhibitors

Circadian adjustment of men and women to night work

Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes

Different patterns of light exposure in relation to melatonin and cortisol rhythms and sleep of night workers

Differential expression of melatonin receptors in spontaneously hypertensive rats

Differential regulation of the rat melatonin receptors: selective age-associated decline and lack of melatonin-induced changes

Differential sensitivity to cations of the melatonin receptors in the rat area postrema and suprachiasmatic nuclei

Discovery of 12-Thiazole Abietanes as Selective Inhibitors of the Human Metabolic Serine Hydrolase hABHD16A

Discovery of triterpenoids as reversible inhibitors of α/β-hydrolase domain containing 12 (ABHD12)

Diurnal rhythm of melatonin binding in the rat suprachiasmatic nucleus

Diurnal rhythm of melatonin in bovine milk: pharmacokinetics of exogenous melatonin in lactating cows and goats

Dopamine stimulates K+ efflux in the chick retina via D1 receptors independently of adenylyl cyclase activation.

Effects of continuous opioid receptor blockade on alcohol intake and up-regulation of opioid receptor subtype signalling in a genetic model of high alcohol drinking.

Effects of melatonin implants in spring on testicular regression and moulting in adult male raccoon dogs (Nyctereutes procynoides)

Effects of melatonin implants on winter fur growth and testicular recrudescence in adult male raccoon dogs (Nyctereutes procyonoides)

Effects of mobile phone radiation on UV-induced skin tumourigenesis in ornithine decarboxylase transgenic and non-transgenic mice.

Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits.

Exposure to a 50-hz magnetic field induces a circadian rhythm in 6-hydroxymelatonin sulfate excretion in mice.

Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes

Functional autoradiography shows unaltered cannabinoid CB1 receptor signalling in hippocampus and cortex of APP/PS1 transgenic mice

Guanosine 5'-(gamma-[35S]thio)triphosphate autoradiography allows selective detection of histamine H3 receptor-dependent G protein activation in rat brain tissue sections.

High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections - Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils

Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptor

Important amino acids for the function of the human MT1 melatonin receptor.

In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048).

Increased tonic cannabinoid CB1R activity and brain region-specific desensitization of CB1R Gi/o signaling axis in mice with global genetic knockout of monoacylglycerol lipase

Intracerebroventricular antisense knockdown of G alpha i2 results in ciliary stasis and ventricular dilatation in the rat.

Inverse agonist exposure enhances ligand binding and G protein activation of the human MT1 melatonin receptor, but leads to receptor down-regulation.

Level and distribution of progesterone in bovine milk: effects of mastitis and milk composition

Lipid phosphate phosphatase inhibitors locally amplify lysophosphatidic acid LPA1 receptor signalling in rat brain cryosections without affecting global LPA degradation

Localization and variable expression of G alpha(i2) in human endometrium and Fallopian tubes.

Long-term induction of haem oxygenase-1 (HSP-32) in astrocytes and microglia following transient focal brain ischaemia in the rat.

Mechanism by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) reduces circulating melatonin levels in the rat.

Melatonin receptor genes.

Milk progesterone in Finnish dairy cows: a field study on the control of artificial insemination and early pregnancy

Monoglyceride lipase as an enzyme hydrolyzing 2-arachidonoylglycerol.

Monoglyceride lipase-like enzymatic activity is responsible for hydrolysis of 2-arachidonoylglycerol in rat cerebellar membranes.

Mutagenesis of human Mel1a melatonin receptor expressed in yeast reveals domains important for receptor function

Neuroanatomical mapping of juvenile rat brain regions with prominent basal signal in [(35)S]GTPgammaS autoradiography.

Oestrus and pregnancy diagnosis by milk progesterone assay in the mare

On the respective roles of nitric oxide and carbon monoxide in long-term potentiation in the hippocampus

On the respective roles of nitric oxide and carbon monoxide in long-term potentiation in the hippocampus.

Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau

Pineal muscarinic phosphoinositide response: pertussis toxin resistant signaling with very low receptor number

Pineal muscarinic phosphoinositide responses: age-associated sensitization, agonist-induced desensitization and increase in melatonin release from cultured pineal glands

Potent and selective N-(4-sulfamoylphenyl)thiourea-based GPR55 agonists

Protective properties of tin- and manganese-centered porphyrins against hydrogen peroxide-mediated injury in rat astroglial cells.

Quantification of lysophosphatidic acids in rat brain tissue by liquid chromatography-electrospray tandem mass spectrometry

Relation of age to circadian adjustment to night work

Renal melatonin excretion in sheep is enhanced by water diuresis

Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors

Selective detection of adenosine A1 receptor-dependent G-protein activity in basal and stimulated conditions of rat brain [35S]guanosine 5'-(gamma-thio)triphosphate autoradiography

Synthesis and CB1 receptor activities of dimethylheptyl derivatives of 2-arachidonoyl glycerol (2-AG) and 2-arachidonyl glyceryl ether (2-AGE).

Synthesis and SAR studies of 2-oxoquinoline derivatives as CB2 receptor inverse agonists.

Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.

Synthesis and preclinical evaluation of [11C]MA-PB-1 for in vivo imaging of brain monoacylglycerol lipase (MAGL).

Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide.

TCDD reduces serum melatonin levels in Long-Evans rats

The 'allosteric modulator' SCH-202676 disrupts G protein-coupled receptor function via sulphydryl-sensitive mechanisms.

The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D-lysophosphatidic acid receptor axis and 5-HT1A receptors in rat brain sections.

The chick retinal melatonin receptor revisited: localization and modulation of agonist binding with guanine nucleotides

The effect of four-day round trip flights over 10 time zones on the circadian variation of salivary melatonin and Cortisol in airline flight attendants

The effect of photoperiod on diel rhythms in serum melatonin, cortisol, glucose, and electrolytes in the common dentex, Dentex dentex

The functional role of cysteines adjacent to the NRY motif of the human MT1 melatonin receptor.

The prediction of the adaptation of circadian rhythms to rapid time zone changes

The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors