Lista de obras - Juan Manuel Castellano - Dominio Público Uruguay

A system biology approach to identify regulatory pathways underlying the neuroendocrine control of female puberty in rats and nonhuman primates

scientific article published on July 2013

Activation of Microglia in Specific Hypothalamic Nuclei and the Cerebellum of Adult Rats Exposed to Neonatal Overnutrition

artículo científico publicado en 2011

Acute inflammation reduces kisspeptin immunoreactivity at the arcuate nucleus and decreases responsiveness to kisspeptin independently of its anorectic effects.

artículo científico publicado en 2010

Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54.

artículo científico publicado en 2004

Alterations in hypothalamic KiSS-1 system in experimental diabetes: early changes and functional consequences.

artículo científico publicado en 2008

An alternative transcription start site yields estrogen-unresponsive Kiss1 mRNA transcripts in the hypothalamus of prepubertal female rats

artículo científico publicado en 2014

Animal Modeling of Early Programming and Disruption of Pubertal Maturation.

artículo científico

Cellular distribution, regulated expression, and functional role of the anorexigenic peptide, NUCB2/nesfatin-1, in the testis

scientific journal article

Changes in hypothalamic KiSS-1 system and restoration of pubertal activation of the reproductive axis by kisspeptin in undernutrition

artículo científico publicado en 2005

Characterization of the Potent Luteinizing Hormone-Releasing Activity of KiSS-1 Peptide, the Natural Ligand of GPR54

artículo científico publicado en 2004

Delayed puberty in spontaneously hypertensive rats involves a primary ovarian failure independent of the hypothalamic KiSS-1/GPR54/GnRH system.

artículo científico publicado en 2009

Desensitization of gonadotropin responses to kisspeptin in the female rat: analyses of LH and FSH secretion at different developmental and metabolic states.

artículo científico publicado en 2008

Development and validation of a method for precise dating of female puberty in laboratory rodents: The puberty ovarian maturation score (Pub-Score).

artículo científico publicado en 2017

Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide.

artículo científico publicado en 2004

Differential modulation of gonadotropin responses to kisspeptin by aminoacidergic, peptidergic, and nitric oxide neurotransmission

artículo científico publicado en 2012

Direct stimulatory effect of ghrelin on pituitary release of LH through a nitric oxide-dependent mechanism that is modulated by estrogen

artículo científico publicado en 2007

Disparate changes in kisspeptin and neurokinin B expression in the arcuate nucleus after sex steroid manipulation reveal differential regulation of the two KNDy peptides in rats

artículo científico publicado en 2014

Early metabolic programming of puberty onset: impact of changes in postnatal feeding and rearing conditions on the timing of puberty and development of the hypothalamic kisspeptin system

artículo científico publicado en 2011

Effects of KiSS-1 peptide, the natural ligand of GPR54, on follicle-stimulating hormone secretion in the rat.

artículo científico publicado en 2005

Effects of galanin-like peptide on luteinizing hormone secretion in the rat: sexually dimorphic responses and enhanced sensitivity at male puberty

artículo científico publicado en 2006

Effects of single or repeated intravenous administration of kisspeptin upon dynamic LH secretion in conscious male rats

artículo científico publicado en 2006

Epigenetic control of female puberty

scientific journal article

Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression

artículo científico publicado en 2015

Expression of KiSS-1 in rat ovary: putative local regulator of ovulation?

artículo científico publicado en 2006

Expression of KiSS-1 in rat oviduct: possible involvement in prevention of ectopic implantation?

scientific journal article

Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats

artículo científico publicado en 2006

Ghrelin inhibits the proliferative activity of immature Leydig cells in vivo and regulates stem cell factor messenger ribonucleic acid expression in rat testis.

artículo científico publicado en 2004

Hypothalamic expression of KiSS-1 system and gonadotropin-releasing effects of kisspeptin in different reproductive states of the female Rat.

artículo científico publicado en 2006

Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3

scientific article published on 07 November 2019

Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat.

artículo científico publicado en 2010

Intergenerational Influence of Paternal Obesity on Metabolic and Reproductive Health Parameters of the Offspring: Male-Preferential Impact and Involvement of Kiss1-Mediated Pathways

artículo científico publicado en 2017

KiSS-1 in the mammalian ovary: distribution of kisspeptin in human and marmoset and alterations in KiSS-1 mRNA levels in a rat model of ovulatory dysfunction.

artículo científico publicado en 2009

Kisspeptin receptor haplo-insufficiency causes premature ovarian failure despite preserved gonadotropin secretion

artículo científico publicado en 2014

Kisspeptins and the control of gonadotropin secretion in male and female rodents.

artículo científico publicado en 2008

Kisspeptins: bridging energy homeostasis and reproduction

scientific article published on 25 August 2010

Loss of Ntrk2/Kiss1r signaling in oocytes causes premature ovarian failure

artículo científico publicado en 2014

Loss-of-function mutations in PNPLA6 encoding neuropathy target esterase underlie pubertal failure and neurological deficits in Gordon Holmes syndrome

artículo científico publicado en 2014

Metabolic and Gonadotropic Impact of Sequential Obesogenic Insults in the Female: Influence of the Loss of Ovarian Secretion.

artículo científico publicado en 2015

Metabolic control of female puberty: potential therapeutic targets.

artículo científico publicado en 2016

Metabolic control of puberty onset: new players, new mechanisms

artículo científico publicado en 2009

Metabolic programming of puberty: sexually dimorphic responses to early nutritional challenges

artículo científico publicado en 2013

Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin signaling

article published in the Proceedings of the National Academy of Sciences of the United States of America

Metabolic regulation of kisspeptin.

artículo científico

Neuromedin s as novel putative regulator of luteinizing hormone secretion.

artículo científico publicado en 2006

Novel role of the anorexigenic peptide neuromedin U in the control of LH secretion and its regulation by gonadal hormones and photoperiod

artículo científico publicado en 2007

Obesity-induced hypogonadism in the male: premature reproductive neuroendocrine senescence and contribution of Kiss1-mediated mechanisms

artículo científico publicado en 2014

Ontogeny and mechanisms of action for the stimulatory effect of kisspeptin on gonadotropin-releasing hormone system of the rat.

artículo científico publicado en 2006

Opposite roles of estrogen receptor (ER)-alpha and ERbeta in the modulation of luteinizing hormone responses to kisspeptin in the female rat: implications for the generation of the preovulatory surge.

artículo científico publicado en 2008

Pattern of orexin expression and direct biological actions of orexin-a in rat testis

scientific journal article

Persistent impairment of hypothalamic KiSS-1 system after exposures to estrogenic compounds at critical periods of brain sex differentiation.

artículo científico publicado en 2008

Role of neurokinin B in the control of female puberty and its modulation by metabolic status

artículo científico publicado en 2012

SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression

scientific article published in Nature Communications

Selective role of neuropeptide Y receptor subtype Y2 in the control of gonadotropin secretion in the rat.

artículo científico publicado en 2007

Stimulatory effect of PYY-(3-36) on gonadotropin secretion is potentiated in fasted rats

artículo científico publicado en 2006

The anorexigenic neuropeptide, nesfatin-1, is indispensable for normal puberty onset in the female rat.

artículo científico

The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system.

artículo científico publicado en 2009

Transcription of the human EAP1 gene is regulated by upstream components of a puberty-controlling Tumor Suppressor Gene network

artículo científico publicado en 2011

Lista de obras de Juan Manuel Castellano

A system biology approach to identify regulatory pathways underlying the neuroendocrine control of female puberty in rats and nonhuman primates

Activation of Microglia in Specific Hypothalamic Nuclei and the Cerebellum of Adult Rats Exposed to Neonatal Overnutrition

Acute inflammation reduces kisspeptin immunoreactivity at the arcuate nucleus and decreases responsiveness to kisspeptin independently of its anorectic effects.

Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54.

Alterations in hypothalamic KiSS-1 system in experimental diabetes: early changes and functional consequences.

An alternative transcription start site yields estrogen-unresponsive Kiss1 mRNA transcripts in the hypothalamus of prepubertal female rats

Animal Modeling of Early Programming and Disruption of Pubertal Maturation.

Cellular distribution, regulated expression, and functional role of the anorexigenic peptide, NUCB2/nesfatin-1, in the testis

Changes in hypothalamic KiSS-1 system and restoration of pubertal activation of the reproductive axis by kisspeptin in undernutrition

Characterization of the Potent Luteinizing Hormone-Releasing Activity of KiSS-1 Peptide, the Natural Ligand of GPR54

Delayed puberty in spontaneously hypertensive rats involves a primary ovarian failure independent of the hypothalamic KiSS-1/GPR54/GnRH system.

Desensitization of gonadotropin responses to kisspeptin in the female rat: analyses of LH and FSH secretion at different developmental and metabolic states.

Development and validation of a method for precise dating of female puberty in laboratory rodents: The puberty ovarian maturation score (Pub-Score).

Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide.

Differential modulation of gonadotropin responses to kisspeptin by aminoacidergic, peptidergic, and nitric oxide neurotransmission

Direct stimulatory effect of ghrelin on pituitary release of LH through a nitric oxide-dependent mechanism that is modulated by estrogen

Disparate changes in kisspeptin and neurokinin B expression in the arcuate nucleus after sex steroid manipulation reveal differential regulation of the two KNDy peptides in rats

Early metabolic programming of puberty onset: impact of changes in postnatal feeding and rearing conditions on the timing of puberty and development of the hypothalamic kisspeptin system

Effects of KiSS-1 peptide, the natural ligand of GPR54, on follicle-stimulating hormone secretion in the rat.

Effects of galanin-like peptide on luteinizing hormone secretion in the rat: sexually dimorphic responses and enhanced sensitivity at male puberty

Effects of single or repeated intravenous administration of kisspeptin upon dynamic LH secretion in conscious male rats

Epigenetic control of female puberty

Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression

Expression of KiSS-1 in rat ovary: putative local regulator of ovulation?

Expression of KiSS-1 in rat oviduct: possible involvement in prevention of ectopic implantation?

Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats

Ghrelin inhibits the proliferative activity of immature Leydig cells in vivo and regulates stem cell factor messenger ribonucleic acid expression in rat testis.

Hypothalamic expression of KiSS-1 system and gonadotropin-releasing effects of kisspeptin in different reproductive states of the female Rat.

Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3

Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat.

Intergenerational Influence of Paternal Obesity on Metabolic and Reproductive Health Parameters of the Offspring: Male-Preferential Impact and Involvement of Kiss1-Mediated Pathways

KiSS-1 in the mammalian ovary: distribution of kisspeptin in human and marmoset and alterations in KiSS-1 mRNA levels in a rat model of ovulatory dysfunction.

Kisspeptin receptor haplo-insufficiency causes premature ovarian failure despite preserved gonadotropin secretion

Kisspeptins and the control of gonadotropin secretion in male and female rodents.

Kisspeptins: bridging energy homeostasis and reproduction

Loss of Ntrk2/Kiss1r signaling in oocytes causes premature ovarian failure

Loss-of-function mutations in PNPLA6 encoding neuropathy target esterase underlie pubertal failure and neurological deficits in Gordon Holmes syndrome

Metabolic and Gonadotropic Impact of Sequential Obesogenic Insults in the Female: Influence of the Loss of Ovarian Secretion.

Metabolic control of female puberty: potential therapeutic targets.

Metabolic control of puberty onset: new players, new mechanisms

Metabolic programming of puberty: sexually dimorphic responses to early nutritional challenges

Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin signaling

Metabolic regulation of kisspeptin.

Neuromedin s as novel putative regulator of luteinizing hormone secretion.

Novel role of the anorexigenic peptide neuromedin U in the control of LH secretion and its regulation by gonadal hormones and photoperiod

Obesity-induced hypogonadism in the male: premature reproductive neuroendocrine senescence and contribution of Kiss1-mediated mechanisms

Ontogeny and mechanisms of action for the stimulatory effect of kisspeptin on gonadotropin-releasing hormone system of the rat.

Opposite roles of estrogen receptor (ER)-alpha and ERbeta in the modulation of luteinizing hormone responses to kisspeptin in the female rat: implications for the generation of the preovulatory surge.

Pattern of orexin expression and direct biological actions of orexin-a in rat testis

Persistent impairment of hypothalamic KiSS-1 system after exposures to estrogenic compounds at critical periods of brain sex differentiation.

Role of neurokinin B in the control of female puberty and its modulation by metabolic status

SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression

Selective role of neuropeptide Y receptor subtype Y2 in the control of gonadotropin secretion in the rat.

Stimulatory effect of PYY-(3-36) on gonadotropin secretion is potentiated in fasted rats

The anorexigenic neuropeptide, nesfatin-1, is indispensable for normal puberty onset in the female rat.

The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system.

Transcription of the human EAP1 gene is regulated by upstream components of a puberty-controlling Tumor Suppressor Gene network