Lista de obras - Amanda K Lukens - Dominio Público Uruguay

A broad analysis of resistance development in the malaria parasite

artículo científico publicado en 2016

A genome-wide map of diversity in Plasmodium falciparum

artículo científico publicado en 2006

Aminoazabenzimidazoles, a novel class of orally active antimalarial agents

artículo científico publicado en 2014

Changes in drug sensitivity and anti-malarial drug resistance mutations over time among Plasmodium falciparum parasites in Senegal

artículo científico publicado en 2013

Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus

artículo científico publicado en 2015

Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria

artículo científico publicado en 2011

Diversity-oriented synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors

artículo científico publicado en 2014

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

artículo científico publicado en 2016

Diversity-oriented synthesis-facilitated medicinal chemistry: toward the development of novel antimalarial agents

artículo científico publicado en 2014

Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype

artículo científico publicado en 2015

Genetic surveillance detects both clonal and epidemic transmission of malaria following enhanced intervention in Senegal

artículo científico publicado en 2013

Genome-Wide Association Studies of Drug-Resistance Determinants

artículo científico publicado en 2016

Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence

artículo científico publicado en 2008

Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance

artículo científico publicado en 2013

Human cerebral malaria and Plasmodium falciparum genotypes in Malawi

artículo científico publicado en 2012

Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum

artículo científico publicado en 2011

Identification of Collateral Sensitivity to Dihydroorotate Dehydrogenase Inhibitors in Plasmodium falciparum

artículo científico publicado en 2018

In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model

artículo científico publicado en 2019

In vivo transcriptome of Plasmodium falciparum reveals overexpression of transcripts that encode surface proteins

artículo científico publicado en 2005

Intramolecular Diaza-Diels-Alder Protocol: A New Diastereoselective and Modular One-Step Synthesis of Constrained Polycyclic Frameworks

artículo científico publicado en 2016

ML238: An Antimalarial Small Molecule of a Unique Structural Class

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics

artículo científico publicado en 2018

New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections ⬇️

artículo científico publicado en 2016

Open-source discovery of chemical leads for next-generation chemoprotective antimalarials

scientific article published on 01 December 2018

Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL), a Resistance Mechanism for Two Distinct Compound Classes

scientific article published on 07 April 2016

Polymorphism in dhfr/dhps genes, parasite density and ex vivo response to pyrimethamine in Plasmodium falciparum malaria parasites in Thies, Senegal

artículo científico publicado en 2013

Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites

artículo científico publicado en 2016

Quantitative Proteomic Profiling Reveals Novel Plasmodium falciparum Surface Antigens and Possible Vaccine Candidates

artículo científico publicado en 2017

SNP genotyping identifies new signatures of selection in a deep sample of West African Plasmodium falciparum malaria parasites

artículo científico publicado en 2012

Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite

artículo científico publicado en 2012

The Adaptive Proline Response in P. falciparum Is Independent of PfeIK1 and eIF2α Signaling

artículo científico publicado en 2019

The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs

artículo científico publicado en 2015

Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate

artículo científico publicado en 2015

Lista de obras de Amanda K Lukens

A broad analysis of resistance development in the malaria parasite

A genome-wide map of diversity in Plasmodium falciparum

Aminoazabenzimidazoles, a novel class of orally active antimalarial agents

Changes in drug sensitivity and anti-malarial drug resistance mutations over time among Plasmodium falciparum parasites in Senegal

Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus

Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria

Diversity-oriented synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

Diversity-oriented synthesis-facilitated medicinal chemistry: toward the development of novel antimalarial agents

Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype

Genetic surveillance detects both clonal and epidemic transmission of malaria following enhanced intervention in Senegal

Genome-Wide Association Studies of Drug-Resistance Determinants

Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence

Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance

Human cerebral malaria and Plasmodium falciparum genotypes in Malawi

Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum

Identification of Collateral Sensitivity to Dihydroorotate Dehydrogenase Inhibitors in Plasmodium falciparum

In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model

In vivo transcriptome of Plasmodium falciparum reveals overexpression of transcripts that encode surface proteins

Intramolecular Diaza-Diels-Alder Protocol: A New Diastereoselective and Modular One-Step Synthesis of Constrained Polycyclic Frameworks

ML238: An Antimalarial Small Molecule of a Unique Structural Class

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics

New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections ⬇️

Open-source discovery of chemical leads for next-generation chemoprotective antimalarials

Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL), a Resistance Mechanism for Two Distinct Compound Classes

Polymorphism in dhfr/dhps genes, parasite density and ex vivo response to pyrimethamine in Plasmodium falciparum malaria parasites in Thies, Senegal

Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites

Quantitative Proteomic Profiling Reveals Novel Plasmodium falciparum Surface Antigens and Possible Vaccine Candidates

SNP genotyping identifies new signatures of selection in a deep sample of West African Plasmodium falciparum malaria parasites

Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite

The Adaptive Proline Response in P. falciparum Is Independent of PfeIK1 and eIF2α Signaling

The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs

Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate