Lista de obras - Arul Chinnaiyan - Dominio Público Uruguay

A Germline DNA Polymorphism Enhances Alternative Splicing of theKLF6Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk

article

A comprehensive approach toward novel serum biomarkers for benign prostatic hyperplasia: the MPSA Consortium

artículos científicos

A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer

artículo científico publicado en 2008

A functional thrombin receptor (PAR1) is expressed on bone-derived prostate cancer cell lines.

artículo científico publicado en 2002

A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors

artículo científico publicado en 2018

ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease

artículo científico publicado en 2006

Abstract 2795: An onco-protein axis linking polycomb repressive complex 2 and polycomb repressive complex 1 through miRNAs in cancer

Abstract 4707: Discovery and characterization of PCAT-1, a novel lincRNA implicated in prostate cancer tumorigenesis

article

Abstract 953: Mechanistic rationale for inhibition of Poly(ADP-Ribose) Polymerase in ETS gene fusion positive prostate cancer

article

Active surveillance for prostate cancer: the role of the pathologist

article

Alpha-Methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions

artículo científico publicado en 2002

An integrative approach to reveal driver gene fusions from paired-end sequencing data in cancer

artículo científico publicado en 2009

Analysis of the androgen receptor-regulated lncRNA landscape identifies a role for ARLNC1 in prostate cancer progression.

artículo científico publicado en 2018

Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

scientific article published on July 2009

Androgen-Independent Prostate Cancer Is a Heterogeneous Group of Diseases

article

Antibody-based detection of ERG rearrangement-positive prostate cancer

artículo científico publicado en 2010

Antibody-independent targeted quantification of TMPRSS2-ERG fusion protein products in prostate cancer.

artículo científico publicado en 2014

Autoantibody signatures in prostate cancer

artículo científico publicado en 2005

Beyond PSA: the next generation of prostate cancer biomarkers

scientific article published on March 2012

Bioinformatics approach leads to the discovery of the TMPRSS2:ETS gene fusion in prostate cancer

artículo científico

Characterization of KRAS rearrangements in metastatic prostate cancer

artículo científico publicado en 2011

Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer

artículo científico publicado en 2008

Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer

artículo científico publicado en 2012

Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast

artículo científico publicado en 2014

Chimeric transcript discovery by paired-end transcriptome sequencing

artículo científico publicado en 2009

Combining urinary detection of TMPRSS2:ERG and PCA3 with serum PSA to predict diagnosis of prostate cancer

artículo científico publicado en 2011

Common gene rearrangements in prostate cancer

artículo científico publicado en 2011

Common structural and epigenetic changes in the genome of castration-resistant prostate cancer

artículo científico publicado en 2011

Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer

article

Consensus statement with recommendations on active surveillance inclusion criteria and definition of progression in men with localized prostate cancer: the critical role of the pathologist

artículo científico publicado en 2014

Coordinated regulation of polycomb group complexes through microRNAs in cancer.

artículo científico publicado en 2011

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer ⬇️

artículo científico publicado en 2015

Decreased alpha-methylacyl CoA racemase expression in localized prostate cancer is associated with an increased rate of biochemical recurrence and cancer-specific death

artículo científico publicado en 2005

Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer

artículo científico publicado en 2011

Defining aggressive prostate cancer using a 12-gene model

artículo científico publicado en 2006

Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing

artículo científico publicado en 2010

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

artículo científico publicado en 2007

EML4-ALK fusion lung cancer: a rare acquired event

artículo científico publicado en 2008

ERG cooperates with androgen receptor in regulating trefoil factor 3 in prostate cancer disease progression

artículo científico publicado en 2010

ETS gene fusions in prostate cancer: from discovery to daily clinical practice

artículo científico publicado en 2009

Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer

artículo científico publicado en 2008

Expressed pseudogenes in the transcriptional landscape of human cancers

artículo científico publicado en 2012

Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo

artículo científico publicado en 2003

Expression of the platelet-derived growth factor receptor in prostate cancer and treatment implications with tyrosine kinase inhibitors

artículo científico publicado en 2004

From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer

artículo científico publicado en 2012

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer

artículo científico publicado en 2011

Gene fusions associated with recurrent amplicons represent a class of passenger aberrations in breast cancer

artículo científico publicado en 2012

Gene-expression profiles in hereditary breast cancer.

artículo científico publicado en 2002

Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma.

artículo científico publicado en 2012

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

artículo científico publicado en 2008

Golgi protein GOLM1 is a tissue and urine biomarker of prostate cancer

artículo científico publicado en 2008

HPeak: an HMM-based algorithm for defining read-enriched regions in ChIP-Seq data

artículo científico publicado en 2010

Heat Shock Protein Beta-1 Modifies Anterior to Posterior Purkinje Cell Vulnerability in a Mouse Model of Niemann-Pick Type C Disease

artículo científico publicado en 2016

Identification of functionally active, low frequency copy number variants at 15q21.3 and 12q21.31 associated with prostate cancer risk

artículo científico publicado en 2012

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

artículo científico publicado en 2018

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

scientific article published on 04 September 2018

Inflammation-Induced Oxidative Stress Mediates Gene Fusion Formation in Prostate Cancer

scientific article published on December 2016

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

scientific article published on 06 July 2016

Integrative Clinical Genomics of Advanced Prostate Cancer.

artículo científico publicado en 2015

Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth

artículo científico publicado en 2015

Integrative analysis of genomic aberrations associated with prostate cancer progression

artículo científico publicado en 2007

Integrative clinical genomics of advanced prostate cancer

artículo científico publicado en 2015

Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression

article

Integrative molecular concept modeling of prostate cancer progression.

artículo científico publicado en 2006

Internet-based Profiler system as integrative framework to support translational research

artículo científico publicado en 2005

JAGGED1 expression is associated with prostate cancer metastasis and recurrence

artículo científico publicado en 2004

KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis.

artículo científico publicado en 2008

Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination

scientific article published on 04 January 2021

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer

artículo científico publicado en 2011

Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model.

artículo científico publicado en 2007

Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets

artículo científico publicado en 2011

Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty.

artículo científico publicado en 2004

Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor target

artículo científico publicado en 2012

Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma

artículo científico publicado en 2013

Overexpression of the Long Non-coding RNA SChLAP1 Independently Predicts Lethal Prostate Cancer

artículo científico publicado en 2015

Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer

artículo científico publicado en 2004

PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer

artículo científico publicado en 2014

Pathway biomarker profiling of localized and metastatic human prostate cancer reveal metastatic and prognostic signatures

artículo científico publicado en 2009

Prevalence of TMPRSS2-ERG fusion prostate cancer among men undergoing prostate biopsy in the United States

artículo científico publicado en 2009

Prostate cancer with Paneth cell-like neuroendocrine differentiation has recognizable histomorphology and harbors AURKA gene amplification

artículo científico publicado en 2014

Publisher Correction: The long tail of oncogenic drivers in prostate cancer

scientific article published on 01 July 2019

RHAMM (CD168) is overexpressed at the protein level and may constitute an immunogenic antigen in advanced prostate cancer disease

artículo científico publicado en 2009

Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

artículo científico publicado en 2010

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

artículo científico publicado en 2005

Recurrent reciprocal RNA chimera involving YPEL5 and PPP1CB in chronic lymphocytic leukemia

artículo científico publicado en 2013

Role of the TMPRSS2-ERG gene fusion in prostate cancer

artículo científico publicado en 2008

Role of transcriptional corepressor CtBP1 in prostate cancer progression

artículo científico publicado en 2012

SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling.

artículo científico publicado en 2017

TMPRSS2-ERG Fusion Prostate Cancer: An Early Molecular Event Associated With Invasion

artículo científico publicado en 2007

TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer

artículo científico publicado en 2006

Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer

artículo científico publicado en 2021

Targeting the MLL complex in castration-resistant prostate cancer

artículo científico publicado en 2015

The critical role of the pathologist in determining eligibility for active surveillance as a management option in patients with prostate cancer: consensus statement with recommendations supported by the College of American Pathologists, Internationa

artículo científico

The lncRNA PCAT29 inhibits oncogenic phenotypes in prostate cancer

artículo científico publicado en 2014

The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex

artículo científico publicado en 2013

The long tail of oncogenic drivers in prostate cancer.

artículo científico publicado en 2018

The role of SPINK1 in ETS rearrangement-negative prostate cancers

artículo científico publicado en 2008

The role of calpain in the proteolytic cleavage of E-cadherin in prostate and mammary epithelial cells

artículo científico publicado en 2002

The role of metastasis-associated protein 1 in prostate cancer progression

artículo científico publicado en 2004

Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes

artículo científico publicado en 2014

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

artículo científico publicado en 2011

Transcriptome sequencing to detect gene fusions in cancer

artículo científico publicado en 2009

Transcriptomic heterogeneity in multifocal prostate cancer

artículo científico publicado en 2018

Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy

scientific article published on 14 April 2009

Urine TMPRSS2:ERG fusion transcript stratifies prostate cancer risk in men with elevated serum PSA.

artículo científico publicado en 2011

Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors

artículo científico publicado en 2004

Whole transcriptome amplification for gene expression profiling and development of molecular archives

artículo científico publicado en 2006

Lista de obras de Arul Chinnaiyan

A Germline DNA Polymorphism Enhances Alternative Splicing of theKLF6Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk

A comprehensive approach toward novel serum biomarkers for benign prostatic hyperplasia: the MPSA Consortium

A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer

A functional thrombin receptor (PAR1) is expressed on bone-derived prostate cancer cell lines.

A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors

ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease

Abstract 2795: An onco-protein axis linking polycomb repressive complex 2 and polycomb repressive complex 1 through miRNAs in cancer

Abstract 4707: Discovery and characterization of PCAT-1, a novel lincRNA implicated in prostate cancer tumorigenesis

Abstract 953: Mechanistic rationale for inhibition of Poly(ADP-Ribose) Polymerase in ETS gene fusion positive prostate cancer

Active surveillance for prostate cancer: the role of the pathologist

Alpha-Methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions

An integrative approach to reveal driver gene fusions from paired-end sequencing data in cancer

Analysis of the androgen receptor-regulated lncRNA landscape identifies a role for ARLNC1 in prostate cancer progression.

Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

Androgen-Independent Prostate Cancer Is a Heterogeneous Group of Diseases

Antibody-based detection of ERG rearrangement-positive prostate cancer

Antibody-independent targeted quantification of TMPRSS2-ERG fusion protein products in prostate cancer.

Autoantibody signatures in prostate cancer

Beyond PSA: the next generation of prostate cancer biomarkers

Bioinformatics approach leads to the discovery of the TMPRSS2:ETS gene fusion in prostate cancer

Characterization of KRAS rearrangements in metastatic prostate cancer

Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer

Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer

Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast

Chimeric transcript discovery by paired-end transcriptome sequencing

Combining urinary detection of TMPRSS2:ERG and PCA3 with serum PSA to predict diagnosis of prostate cancer

Common gene rearrangements in prostate cancer

Common structural and epigenetic changes in the genome of castration-resistant prostate cancer

Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer

Consensus statement with recommendations on active surveillance inclusion criteria and definition of progression in men with localized prostate cancer: the critical role of the pathologist

Coordinated regulation of polycomb group complexes through microRNAs in cancer.

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer ⬇️

Decreased alpha-methylacyl CoA racemase expression in localized prostate cancer is associated with an increased rate of biochemical recurrence and cancer-specific death

Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer

Defining aggressive prostate cancer using a 12-gene model

Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

EML4-ALK fusion lung cancer: a rare acquired event

ERG cooperates with androgen receptor in regulating trefoil factor 3 in prostate cancer disease progression

ETS gene fusions in prostate cancer: from discovery to daily clinical practice

Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer

Expressed pseudogenes in the transcriptional landscape of human cancers

Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo

Expression of the platelet-derived growth factor receptor in prostate cancer and treatment implications with tyrosine kinase inhibitors

From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer

Gene fusions associated with recurrent amplicons represent a class of passenger aberrations in breast cancer

Gene-expression profiles in hereditary breast cancer.

Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

Golgi protein GOLM1 is a tissue and urine biomarker of prostate cancer

HPeak: an HMM-based algorithm for defining read-enriched regions in ChIP-Seq data

Heat Shock Protein Beta-1 Modifies Anterior to Posterior Purkinje Cell Vulnerability in a Mouse Model of Niemann-Pick Type C Disease

Identification of functionally active, low frequency copy number variants at 15q21.3 and 12q21.31 associated with prostate cancer risk

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

Inflammation-Induced Oxidative Stress Mediates Gene Fusion Formation in Prostate Cancer

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

Integrative Clinical Genomics of Advanced Prostate Cancer.

Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth

Integrative analysis of genomic aberrations associated with prostate cancer progression

Integrative clinical genomics of advanced prostate cancer

Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression

Integrative molecular concept modeling of prostate cancer progression.

Internet-based Profiler system as integrative framework to support translational research

JAGGED1 expression is associated with prostate cancer metastasis and recurrence

KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis.

Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer

Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model.

Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets

Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty.

Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor target

Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma

Overexpression of the Long Non-coding RNA SChLAP1 Independently Predicts Lethal Prostate Cancer

Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer

PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer

Pathway biomarker profiling of localized and metastatic human prostate cancer reveal metastatic and prognostic signatures