Lista de obras - Avrum Spira - Dominio Público Uruguay

A chronic obstructive pulmonary disease related signature in squamous cell lung cancer

artículo científico publicado en 2010

A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment

artículo científico publicado en 2013

A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK

artículo científico publicado en 2012

A pharmacogenomic method for individualized prediction of drug sensitivity

artículo científico publicado en 2011

A prediction model for lung cancer diagnosis that integrates genomic and clinical features

artículo científico publicado en 2008

Airway PI3K pathway activation is an early and reversible event in lung cancer development

artículo científico publicado en 2010

Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer

article

Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity

artículo científico publicado en 2013

Airway gene expression in chronic obstructive pulmonary disease

artículo científico publicado en 2009

Alterations in gene expression in T1 alpha null lung: a model of deficient alveolar sac development

scientific journal article

Apoptosis genes in human alveolar macrophages infected with virulent or attenuated Mycobacterium tuberculosis: a pivotal role for tumor necrosis factor

artículo científico publicado en 2003

Applying gene expression microarrays to pulmonary disease

artículo científico publicado en 2011

Assessment of microRNA differential expression and detection in multiplexed small RNA sequencing data

artículo científico publicado en 2014

Bridging the clinical gaps: genetic, epigenetic and transcriptomic biomarkers for the early detection of lung cancer in the post-National Lung Screening Trial era ⬇️

artículo científico publicado el 19 de julio de 2013

Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction

artículo científico publicado en 2007

Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution

scientific article published on 11 December 2019

Characterizing the impact of smoking and lung cancer on the airway transcriptome using RNA-Seq

artículo científico publicado en 2011

Clinical impact of high-throughput gene expression studies in lung cancer

artículo científico publicado en 2009

Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers

artículo científico publicado en 2009

Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement

scientific article published on 01 December 2018

Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions

scientific article published on 21 January 2019

Discovering biological connections between experimental conditions based on common patterns of differential gene expression

artículo científico publicado en 2011

Effect of Intermittent Versus Continuous Low-Dose Aspirin on Nasal Epithelium Gene Expression in Current Smokers: A Randomized, Double-Blinded Trial

scientific article published on 26 August 2019

Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD

artículo científico publicado en 2019

Effects of cigarette smoke on the human airway epithelial cell transcriptome

artículo científico publicado en 2004

Enriching the molecular definition of the airway "field of cancerization:" establishing new paradigms for the patient at risk for lung cancer

artículo científico publicado en 2012

Evolving Concepts in Lung Carcinogenesis ⬇️

artículo científico publicado el 15 de abril de 2011

Gene expression profiling of human lung tissue from smokers with severe emphysema

artículo científico publicado en 2004

Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction

artículo científico publicado en 2014

Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer

artículo científico publicado en 2010

Genetics and genomics of chronic obstructive pulmonary disease

artículo científico publicado en 2009

Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors

artículo científico publicado en 2012

Hepatocyte-specific mutation of both NF-κB RelA and STAT3 abrogates the acute phase response in mice

artículo científico publicado en 2012

Identification Of Lung Disease-Associated Novel Transcripts And Alternative Splicing By RNA-Sequencing

Identification of transforming growth factor-beta-regulated microRNAs and the microRNA-targetomes in primary lung fibroblasts

artículo científico publicado en 2017

Identifying Novel Transcripts And Alternative Splicing Associated With The ILD And COPD Lung Transcriptome Using MRNA-Seq

scholarly article published May 2011

Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD

artículo científico publicado en 2020

Impact of cigarette smoke on the normal airway transcriptome

artículo científico publicado en 2004

Influence of vitamin D status and vitamin D3 supplementation on genome wide expression of white blood cells: a randomized double-blind clinical trial

artículo científico publicado en 2013

Integrated Genomics Reveals Convergent Transcriptomic Networks Underlying Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

artículo científico publicado en 2016

Lung cancer biomarkers: FISHing in the sputum for risk assessment and early detection

artículo científico publicado en 2010

MiRNAs as regulators of the response to inhaled environmental toxins and airway carcinogenesis ⬇️

artículo científico publicado el 27 de abril de 2011

MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium

scholarly article

Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions

artículo científico publicado en 2019

Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes

artículo científico publicado en 2011

Moving beyond gene expression: identification of lung-disease-associated novel transcripts and alternative splicing by RNA sequencing.

artículo científico publicado en 2012

Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer

artículo científico publicado en 2010

Pulmonary mucormycosis in the setting of chronic obstructive pulmonary disease. A case report and review of the literature

artículo científico publicado en 2002

Residual expression of reprogramming factors affects the transcriptional program and epigenetic signatures of induced pluripotent stem cells

artículo científico publicado en 2012

Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression

artículo científico publicado en 2007

SIEGE: Smoking Induced Epithelial Gene Expression Database

artículo científico publicado en 2005

SIRT1 pathway dysregulation in the smoke-exposed airway epithelium and lung tumor tissue

artículo científico publicado en 2012

Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium

artículo científico publicado en 2009

Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium

artículo científico publicado en 2008

State of the art. Chronic obstructive pulmonary disease, inflammation, and lung cancer

artículo científico publicado en 2006

The SERPINE2 gene is associated with chronic obstructive pulmonary disease

artículo científico publicado en 2005

The SERPINE2 gene is associated with chronic obstructive pulmonary disease

article

The field of tissue injury in the lung and airway

artículo científico publicado en 2008

Transcription factor Klf4, induced in the lung by oxygen at birth, regulates perinatal fibroblast and myofibroblast differentiation

scientific journal article

Transcriptomic studies of the airway field of injury associated with smoking-related lung disease

artículo científico publicado en 2011

Translating the COPD transcriptome: insights into pathogenesis and tools for clinical management

artículo científico publicado en 2008

Update in Lung Cancer 2014

artículo científico publicado en 2015

Update in Lung Cancer 2015.

artículo científico publicado en 2016

Upper Airway Gene Expression As A Biomarker Of Active And Secondhand Smoke Exposure

article

Upper airway gene expression in smokers: the mouth as a "window to the soul" of lung carcinogenesis?

artículo científico publicado en 2010

miR-129 regulates cell proliferation by downregulating Cdk6 expression

artículo científico publicado en 2010

miR-638 regulates gene expression networks associated with emphysematous lung destruction

artículo científico publicado en 2013

Lista de obras de Avrum Spira

A chronic obstructive pulmonary disease related signature in squamous cell lung cancer

A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment

A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK

A pharmacogenomic method for individualized prediction of drug sensitivity

A prediction model for lung cancer diagnosis that integrates genomic and clinical features

Airway PI3K pathway activation is an early and reversible event in lung cancer development

Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer

Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity

Airway gene expression in chronic obstructive pulmonary disease

Alterations in gene expression in T1 alpha null lung: a model of deficient alveolar sac development

Apoptosis genes in human alveolar macrophages infected with virulent or attenuated Mycobacterium tuberculosis: a pivotal role for tumor necrosis factor

Applying gene expression microarrays to pulmonary disease

Assessment of microRNA differential expression and detection in multiplexed small RNA sequencing data

Bridging the clinical gaps: genetic, epigenetic and transcriptomic biomarkers for the early detection of lung cancer in the post-National Lung Screening Trial era ⬇️

Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction

Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution

Characterizing the impact of smoking and lung cancer on the airway transcriptome using RNA-Seq

Clinical impact of high-throughput gene expression studies in lung cancer

Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers

Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement

Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions

Discovering biological connections between experimental conditions based on common patterns of differential gene expression

Effect of Intermittent Versus Continuous Low-Dose Aspirin on Nasal Epithelium Gene Expression in Current Smokers: A Randomized, Double-Blinded Trial

Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD

Effects of cigarette smoke on the human airway epithelial cell transcriptome

Enriching the molecular definition of the airway "field of cancerization:" establishing new paradigms for the patient at risk for lung cancer

Evolving Concepts in Lung Carcinogenesis ⬇️

Gene expression profiling of human lung tissue from smokers with severe emphysema

Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction

Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer

Genetics and genomics of chronic obstructive pulmonary disease

Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors

Hepatocyte-specific mutation of both NF-κB RelA and STAT3 abrogates the acute phase response in mice

Identification Of Lung Disease-Associated Novel Transcripts And Alternative Splicing By RNA-Sequencing

Identification of transforming growth factor-beta-regulated microRNAs and the microRNA-targetomes in primary lung fibroblasts

Identifying Novel Transcripts And Alternative Splicing Associated With The ILD And COPD Lung Transcriptome Using MRNA-Seq

Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD

Impact of cigarette smoke on the normal airway transcriptome

Influence of vitamin D status and vitamin D3 supplementation on genome wide expression of white blood cells: a randomized double-blind clinical trial

Integrated Genomics Reveals Convergent Transcriptomic Networks Underlying Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

Lung cancer biomarkers: FISHing in the sputum for risk assessment and early detection

MiRNAs as regulators of the response to inhaled environmental toxins and airway carcinogenesis ⬇️

MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium

Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions

Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes

Moving beyond gene expression: identification of lung-disease-associated novel transcripts and alternative splicing by RNA sequencing.

Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer

Pulmonary mucormycosis in the setting of chronic obstructive pulmonary disease. A case report and review of the literature

Residual expression of reprogramming factors affects the transcriptional program and epigenetic signatures of induced pluripotent stem cells

Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression

SIEGE: Smoking Induced Epithelial Gene Expression Database

SIRT1 pathway dysregulation in the smoke-exposed airway epithelium and lung tumor tissue

Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium

Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium

State of the art. Chronic obstructive pulmonary disease, inflammation, and lung cancer

The SERPINE2 gene is associated with chronic obstructive pulmonary disease

The SERPINE2 gene is associated with chronic obstructive pulmonary disease

The field of tissue injury in the lung and airway

Transcription factor Klf4, induced in the lung by oxygen at birth, regulates perinatal fibroblast and myofibroblast differentiation

Transcriptomic studies of the airway field of injury associated with smoking-related lung disease

Translating the COPD transcriptome: insights into pathogenesis and tools for clinical management

Update in Lung Cancer 2014

Update in Lung Cancer 2015.

Upper Airway Gene Expression As A Biomarker Of Active And Secondhand Smoke Exposure

Upper airway gene expression in smokers: the mouth as a "window to the soul" of lung carcinogenesis?

miR-129 regulates cell proliferation by downregulating Cdk6 expression

miR-638 regulates gene expression networks associated with emphysematous lung destruction