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Lista de obras de Lubbe Wiesner

2,4-Diaminothienopyrimidines as orally active antimalarial agents

artículo científico publicado en 2014

A liquid-liquid LC/MS/MS assay for the determination of artemether and DHA in malaria patient samples

artículo científico publicado en 2011

Absorption of the novel artemisinin derivatives artemisone and artemiside: potential application of Pheroid™ technology.

artículo científico publicado en 2011

An Expanded Analysis of Pharmacogenetics Determinants of Efavirenz Response that Includes 3'-UTR Single Nucleotide Polymorphisms among Black South African HIV/AIDS Patients

artículo científico publicado en 2015

An LC-MS/MS method for the determination of ofloxacin in 20 μl human plasma

artículo científico publicado en 2011

Antimalarial Pyrido[1,2-a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model.

artículo científico publicado en 2017

Antimalarial and anticancer activities of artemisinin-quinoline hybrid-dimers and pharmacokinetic properties in mice.

artículo científico publicado en 2012

Antimalarial benzoheterocyclic 4-aminoquinolines: Structure-activity relationship, in vivo evaluation, mechanistic and bioactivation studies

artículo científico publicado en 2015

Antiplasmodial activity, in vivo pharmacokinetics and anti-malarial efficacy evaluation of hydroxypyridinone hybrids in a mouse model

artículo científico publicado en 2015

Arylacetamide deacetylase (AADAC) gene polymorphism and HIV infection affect the exposure of Rifapentine: a population pharmacokinetics analysis

article

Bioavailability of two licensed paediatric rifampicin suspensions: implications for quality control programmes.

artículo científico publicado en 2016

Challenges in diagnosis and management of Cryptococcal immune reconstitution inflammatory syndrome (IRIS) in resource limited settings.

artículo científico publicado en 2012

Combinations of potent topical steroids, mercury and hydroquinone are common in internationally manufactured skin-lightening products: a spectroscopic study.

artículo científico publicado en 2015

Correlation of hair and plasma efavirenz concentrations in HIV-positive South Africans

article

Cyclopalladated organosilane-tethered thiosemicarbazones: novel strategies for improving antiplasmodial activity

artículo científico publicado en 2016

Design, synthesis, and In vitro antituberculosis activity of 2(5H)-Furanone derivatives

artículo científico publicado en 2016

Determinants of virological outcome and adverse events in African children treated with paediatric nevirapine fixed-dose-combination tablets

artículo científico publicado en 2017

Development and validation of a LC-MS/MS method for the quantitation of lumefantrine in mouse whole blood and plasma

artículo científico publicado en 2015

Differences in genetic variants in lopinavir disposition among HIV-infected Bantu Africans

artículo científico publicado en 2016

Discovery of False Elite Controllers: HIV Antibody-Positive RNA-Negative Blood Donors Found To Be on Antiretroviral Therapy

scientific article published on 01 July 2019

Discovery of Novel Cyclic Ethers with Synergistic Antiplasmodial Activity in Combination with Valinomycin

artículo científico publicado en 2021

Drug-drug interactions between bedaquiline and the antiretrovirals lopinavir/ritonavir and nevirapine in HIV-infected patients with drug-resistant TB.

artículo científico publicado en 2016

Effect of First-Line Antituberculosis Therapy on Nevirapine Pharmacokinetics in Children Younger than Three Years Old

artículo científico publicado en 2019

Effect of Isoniazid Intake on Ethionamide Pharmacokinetics and Target Attainment in Multidrug-Resistant Tuberculosis Patients

artículo científico publicado en 2021

Effect of Lopinavir and Nevirapine Concentrations on Viral Outcomes in Protease Inhibitor-experienced HIV-infected Children

artículo científico publicado en 2016

Effect of Moringa oleifera Lam. leaf powder on the pharmacokinetics of nevirapine in HIV-infected adults: a one sequence cross-over study

scientific article published on 14 March 2017

Effect of SLCO1B1 Polymorphisms on Rifabutin Pharmacokinetics in African HIV-Infected Patients with Tuberculosis.

artículo científico publicado en 2015

Effect of diurnal variation, CYP2B6 genotype and age on the pharmacokinetics of nevirapine in African children

artículo científico publicado en 2016

Effect of rifampin/isoniazid-containing antituberculosis therapy on efavirenz pharmacokinetics in HIV-infected children aged 3 to 14 years old

article

Effects of CYP2B6 and CYP1A2 Genetic Variation on Nevirapine Plasma Concentration and Pharmacodynamics as Measured by CD4 Cell Count in Zimbabwean HIV-Infected Patients

artículo científico publicado en 2015

Efficacy and pharmacokinetic evaluation of a novel anti-malarial compound (NP046) in a mouse model

artículo científico publicado en 2015

Efficacy of artemether-lumefantrine in relation to drug exposure in children with and without severe acute malnutrition: an open comparative intervention study in Mali and Niger

artículo científico publicado en 2016

Evaluation of an immunoassay for determination of plasma efavirenz concentrations in resource-limited settings

artículo científico publicado en 2014

Evaluation of the Adequacy of the 2010 Revised World Health Organization Recommended Dosages of the First-line Antituberculosis Drugs for Children

artículo científico

Exploring the pharmacokinetics of oral ketamine in children undergoing burns procedures

artículo científico publicado en 2011

Formulation and evaluation of Pheroid vesicles containing mefloquine for the treatment of malaria

artículo científico publicado en 2013

HIV-1 Coinfection Does Not Reduce Exposure to Rifampin, Isoniazid, and Pyrazinamide in South African Tuberculosis Outpatients

artículo científico publicado en 2016

Herb-Drug Pharmacokinetic Interactions: Transport and Metabolism of Indinavir in the Presence of Selected Herbal Products.

artículo científico publicado en 2015

Highly active 4-aminoquinoline–pyrimidine based molecular hybrids as potential next generation antimalarial agents

scholarly article in RSC Advances, vol. 5 no. 36, 2015

Improved antiparasitic activity by incorporation of organosilane entities into half-sandwich ruthenium(II) and rhodium(III) thiosemicarbazone complexes

artículo científico publicado en 2015

In Vitro Efficacies, ADME, and Pharmacokinetic Properties of Phenoxazine Derivatives Active against Mycobacterium tuberculosis

scientific article published on 22 October 2019

In Vitro and In Vivo Pharmacokinetics of Aminoalkylated Diarylpropanes NP085 and NP102

artículo científico publicado en 2016

In vivo efficacy and bioavailability of lumefantrine: Evaluating the application of Pheroid technology

artículo científico publicado en 2015

Interaction between artemether-lumefantrine and nevirapine-based antiretroviral therapy in HIV-1-infected patients.

artículo científico publicado en 2011

Intestinal Transport Characteristics and Metabolism of C-Glucosyl Dihydrochalcone, Aspalathin

artículo científico publicado en 2017

Linezolid Pharmacokinetics in South African Patients with Drug-Resistant Tuberculosis and a High Prevalence of HIV Coinfection

artículo científico publicado en 2019

Lipid-based nutrient supplements do not affect efavirenz but lower plasma nevirapine concentrations in Ethiopian adult HIV patients

artículo científico publicado en 2015

Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a SoftFocus kinase library: part 1.

artículo científico publicado en 2014

Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a softfocus kinase library: part 2.

artículo científico publicado en 2014

Melamine contamination in nutritional supplements--Is it an alarm bell for the general consumer, athletes, and 'Weekend Warriors'?

artículo científico publicado en 2015

Moxifloxacin population pharmacokinetics and model-based comparison of efficacy between moxifloxacin and ofloxacin in African patients

artículo científico publicado en 2013

Moxifloxacin population pharmacokinetics in patients with pulmonary tuberculosis and the effect of intermittent high-dose rifapentine

artículo científico publicado en 2012

Nutritional supplementation increases rifampin exposure among tuberculosis patients coinfected with HIV

artículo científico publicado en 2014

Oral lipid-based nanoformulation of tafenoquine enhanced bioavailability and blood stage antimalarial efficacy and led to a reduction in human red blood cell loss in mice.

artículo científico publicado en 2015

Pediatric Antiretroviral Therapeutic Drug Monitoring: A Five and a Half Year Experience from a South African Tertiary Hospital

artículo científico publicado en 2019

Pharmacokinetic evaluation of lisinopril-tryptophan, a novel C-domain ACE inhibitor

artículo científico publicado en 2014

Pharmacokinetic profile and safety of adjusted doses of darunavir/ritonavir with rifampicin in people living with HIV

scientific article published on 01 April 2020

Pharmacokinetics and Safety of Ofloxacin in Children with Drug-Resistant Tuberculosis.

artículo científico publicado en 2015

Pharmacokinetics and safety of moxifloxacin in children with multidrug-resistant tuberculosis.

artículo científico publicado en 2014

Pharmacokinetics and safety of rifabutin in young HIV-infected children receiving rifabutin and lopinavir/ritonavir

artículo científico publicado en 2014

Pharmacokinetics of First-Line Antituberculosis Drugs Using WHO Revised Dosage in Children With Tuberculosis With and Without HIV Coinfection

artículo científico publicado en 2015

Pharmacokinetics of Isoniazid, Pyrazinamide, and Ethambutol in Newly Diagnosed Pulmonary TB Patients in Tanzania

artículo científico publicado en 2015

Pharmacokinetics of Rifampin, Isoniazid, Pyrazinamide, and Ethambutol in Infants Dosed According to Revised WHO-Recommended Treatment Guidelines.

artículo científico publicado en 2016

Pharmacokinetics of adjusted-dose 8-hourly lopinavir/ritonavir in HIV-infected children co-treated with rifampicin

scientific article published on 01 August 2019

Pharmacokinetics of efavirenz and treatment of HIV-1 among pregnant women with and without tuberculosis coinfection

artículo científico publicado en 2014

Pharmacokinetics of ofloxacin and levofloxacin for prevention and treatment of multidrug-resistant tuberculosis in children.

scientific article published on 18 February 2014

Pharmacokinetics of the First-Line Antituberculosis Drugs in Ghanaian Children with Tuberculosis with or without HIV Coinfection

artículo científico publicado en 2016

Pharmacokinetics, Safety, and Dosing of Novel Pediatric Levofloxacin Dispersible Tablets in Children with Multidrug-Resistant Tuberculosis Exposure

scientific article published on 27 March 2019

Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies

artículo científico publicado en 2019

Plasma Efavirenz Exposure, Sex, and Age Predict Virological Response in HIV-Infected African Children

artículo científico publicado en 2016

Plasma lopinavir concentrations predict virological failure in a cohort of South African children initiating a protease-inhibitor-based regimen

artículo científico publicado en 2014

Poor Penetration of Antibiotics Into Pericardium in Pericardial Tuberculosis

artículo científico publicado en 2015

Population Pharmacokinetics of Isoniazid, Pyrazinamide, and Ethambutol in Pregnant South African Women with Tuberculosis and HIV

scientific article published on 21 February 2020

Population Pharmacokinetics of Rifampin in Pregnant Women with Tuberculosis and HIV Coinfection in Soweto, South Africa

artículo científico publicado en 2015

Population pharmacokinetics and pharmacodynamics of ofloxacin in South African patients with multidrug-resistant tuberculosis

artículo científico publicado en 2012

Population pharmacokinetics of cycloserine, and pharmacokinetic/pharmacodynamic target attainment, in MDR-tuberculosis patients dosed with terizidone

artículo científico publicado en 2020

Population pharmacokinetics of efavirenz in HIV and TB/HIV coinfected children: the significance of genotype-guided dosing

scientific article published on 01 September 2019

Potent in vivo anti-malarial activity and representative snapshot pharmacokinetic evaluation of artemisinin-quinoline hybrids.

artículo científico publicado en 2013

Pretomanid Pharmacokinetics in the Presence of Rifamycins: interim Results from a Randomized Trial among Patients with Tuberculosis

scientific article published on 23 November 2020

Prevention of TB using rifampicin plus isoniazid reduces nevirapine concentrations in HIV-exposed infants

artículo científico publicado en 2017

Random lopinavir concentrations predict resistance on lopinavir-based antiretroviral therapy

artículo científico publicado en 2016

Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy

artículo científico publicado en 2014

Relation between organophosphate pesticide metabolite concentrations with pesticide exposures, socio-economic factors and lifestyles: A cross-sectional study among school boys in the rural Western Cape, South Africa

artículo científico publicado en 2021

Safety, Tolerability, Pharmacokinetics, and Antimalarial Activity of the Novel Plasmodium Phosphatidylinositol 4-Kinase Inhibitor MMV390048 in Healthy Volunteers

artículo científico publicado en 2020

Sex differences in responses to antiretroviral treatment in South African HIV-infected children on ritonavir-boosted lopinavir- and nevirapine-based treatment

artículo científico publicado en 2014

Structure-Activity Relationship Studies of Orally Active Antimalarial 2,4-Diamino-thienopyrimidines

artículo científico publicado en 2015

Syntheses and in Vitro Antiplasmodial Activity of Aminoalkylated Chalcones and Analogues

artículo científico publicado en 2015

Synthesis and evaluation of hybrid drugs for a potential HIV/AIDS-malaria combination therapy

artículo científico publicado en 2012

Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds

artículo científico publicado en 2013

The development and validation of an LC-MS/MS method for the determination of a new anti-malarial compound (TK900D) in human whole blood and its application to pharmacokinetic studies in mice

artículo científico publicado en 2014

The impact of genetic polymorphisms on the pharmacokinetics of efavirenz in African children

artículo científico publicado en 2016

The interaction between artemether-lumefantrine and lopinavir/ritonavir-based antiretroviral therapy in HIV-1 infected patients

artículo científico publicado en 2016

The pharmacokinetics of lopinavir/ritonavir when given with isoniazid in South African HIV-infected individuals.

artículo científico publicado en 2015

The pharmacokinetics of nevirapine when given with isoniazid in South African HIV-infected individuals

artículo científico publicado en 2013

Therapeutic drug monitoring of amlodipine and the Z-FHL/HHL ratio: Adherence tools in patients referred for apparent treatment-resistant hypertension.

artículo científico publicado en 2017

Undisclosed HIV infection and antiretroviral therapy use in the Kenya AIDS indicator survey 2012: relevance to national targets for HIV diagnosis and treatment

artículo científico publicado en 2016

Viral suppression following switch to second-line antiretroviral therapy: associations with nucleoside reverse transcriptase inhibitor resistance and subtherapeutic drug concentrations prior to switch

scientific article published on 13 August 2013

Who Needs to Be Targeted for HIV Testing and Treatment in KwaZulu-Natal? Results From a Population-Based Survey

artículo científico publicado en 2016

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