Filtros de búsqueda

Lista de obras de Robert Snoeck

(+-)-carbocyclic 5'-nor-2'-deoxyguanosine and related purine derivatives: synthesis and antiviral properties

artículo científico publicado en 1992

(D)- and (L)-cyclohexenyl-G, a new class of antiviral agents: synthesis, conformational analysis, molecular modeling, and biological activity

artículo científico publicado en 2001

(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replication

artículo científico publicado en 1988

(±)-7-deazaaristeromycin lacking the hydroxymethyl substituent

artículo científico publicado en 1993

2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743.

artículo científico publicado en 2009

2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections

artículo científico publicado en 2002

3-Benzamido, Ureido and Thioureidoimidazo[1,2-a]pyridine Derivatives as Potential Antiviral Agents ⬇️

artículo científico publicado el 1 de diciembre de 2001

4"-Benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action

artículo científico publicado en 2008

4-Benzyloxy-gamma-sultone derivatives: discovery of a novel family of non-nucleoside inhibitors of human cytomegalovirus and varicella zoster virus

artículo científico publicado en 2009

4-Benzyloxy-γ-Sultone Derivatives: Discovery of a Novel Family of Non-Nucleoside Inhibitors of Human Cytomegalovirus and Varicella Zoster Virus

5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-chlorothien-2-yl)-2'-deoxyuridine are equipotent to (E)-5-(2-bromovinyl)-2'-deoxyuridine in the inhibition of herpes simplex virus type I replication

artículo científico publicado en 1991

5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidines-acyclic nucleoside phosphonate analogues with antiviral activity

artículo científico publicado en 2003

5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells

artículo científico publicado en 2007

6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activity

artículo científico publicado en 2002

6-[2-phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: a new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity

artículo científico publicado en 2004

9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo

artículo científico publicado en 1991

A European multi-centre External Quality Assessment (EQA) study on phenotypic and genotypic methods used for Herpes Simplex Virus (HSV) drug resistance testing.

artículo científico publicado en 2017

A case of human orf in an immunocompromised patient treated successfully with cidofovir cream

artículo científico publicado en 2001

A multi-targeted drug candidate with dual anti-HIV and anti-HSV activity

artículo científico publicado en 2013

A rapid phenotypic assay for detection of acyclovir-resistant varicella-zoster virus with mutations in the thymidine kinase open reading frame

artículo científico publicado en 2000

Abatement of Cutaneous Kaposi's Sarcoma Associated with Cidofovir Treatment

article

Activities of acyclic nucleoside phosphonates against Orf virus in human and ovine cell monolayers and organotypic ovine raft cultures

artículo científico publicado en 2005

Activities of alkoxyalkyl esters of cidofovir (CDV), cyclic CDV, and (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine against orthopoxviruses in cell monolayers and in organotypic cultures

artículo científico publicado en 2006

Activities of different classes of acyclic nucleoside phosphonates against BK virus in primary human renal cells.

artículo científico publicado en 2011

Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models ⬇️

artículo científico publicado en 2007

Activity and mechanism of action of HDVD, a novel pyrimidine nucleoside derivative with high levels of selectivity and potency against gammaherpesviruses

artículo científico publicado en 2013

Activity of different antiviral drug combinations against human cytomegalovirus replication in vitro

artículo científico publicado en 1992

Activity of the anti-orthopoxvirus compound ST-246 against vaccinia, cowpox and camelpox viruses in cell monolayers and organotypic raft cultures

artículo científico publicado en 2007

Acyclic nucleoside phosphonates containing the amide bond

artículo científico publicado en 2016

Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: efficient synthesis and antiviral activity

artículo científico publicado en 2011

Acyclic/carbocyclic guanosine analogues as anti-herpesvirus agents.

artículo científico publicado en 2001

Acyclovir-resistant herpes simplex encephalitis in a patient treated with anti-tumor necrosis factor-α monoclonal antibodies

artículo científico publicado en 2013

Adjuvant low-dose cidofovir therapy for BK polyomavirus interstitial nephritis in renal transplant recipients.

artículo científico publicado en 2005

Advances in the treatment of varicella-zoster virus infections.

artículo científico

Alkenyl substituted bicyclic nucleoside analogues retain nanomolar potency against Varicella Zoster Virus

artículo científico publicado en 2009

Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis

article

Amidate Prodrugs of Cyclic 9-()-[3-Hydroxy-2-(phosphonomethoxy)propyl]adenine with Potent Anti-Herpesvirus Activity

An epimer of 5'-noraristeromycin and its antiviral properties.

artículo científico publicado en 1994

Anti-(herpes simplex virus) activity of 4'-thio-2'-deoxyuridines: a biochemical investigation for viral and cellular target enzymes

artículo científico publicado en 2000

Anti-influenza virus activity and structure-activity relationship of aglycoristocetin derivatives with cyclobutenedione carrying hydrophobic chains.

artículo científico publicado en 2009

Anti-varicella-zoster virus bicyclic nucleosides: replacement of furo by pyrro base reduces antiviral potency

artículo científico publicado en 2000

Antiadenovirus activities of several classes of nucleoside and nucleotide analogues

artículo científico publicado en 2005

Antiherpesvirus activities of two novel 4'-thiothymidine derivatives, KAY-2-41 and KAH-39-149, are dependent on viral and cellular thymidine kinases

artículo científico publicado en 2014

Antiproliferative and apoptotic effects of iron chelators on human cervical carcinoma cells

artículo científico publicado en 2002

Antitumor Potential of Acyclic Nucleoside Phosphonates

artículo científico publicado en 1999

Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives

scientific article published on 28 September 2019

Antivaccinia activities of acyclic nucleoside phosphonate derivatives in epithelial cells and organotypic cultures

artículo científico publicado en 2002

Antiviral Drug-Resistance Typing Reveals Compartmentalization and Dynamics of Acyclovir-Resistant Herpes Simplex Virus Type-2 (HSV-2) in a Case of Neonatal Herpes

artículo científico publicado en 2013

Antiviral Potency of ST-246 on the Production of Enveloped Orthopoxviruses and Characterization of ST-246 Resistant Vaccinia, Cowpox and Camelpox Viruses

article

Antiviral activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4- carboxamide and related compounds

artículo científico publicado en 1991

Antiviral activity of 3-(3,5-dimethylbenzyl)uracil derivatives against HIV-1 and HCMV.

artículo científico publicado en 2007

Antiviral activity of HPMPC (cidofovir) against orf virus infected lambs

artículo científico publicado en 2006

Antiviral activity of a novel compound P-4018 against different strains of herpes simplex virus in vitro and in vivo

artículo científico publicado en 1997

Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique

artículo científico publicado en 1991

Antiviral activity of ganciclovir elaidic acid ester against herpesviruses

artículo científico publicado en 2000

Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds

artículo científico publicado en 2007

Antiviral activity spectrum of phenoxazine nucleoside derivatives

scientific article published on 23 January 2019

Antiviral and Cytostatic Evaluation of 5-(1-Halo-2-sulfonylvinyl)- and 5-(2-Furyl)uracil Nucleosides.

artículo científico publicado en 2017

Antiviral and cytostatic evaluation of the novel 6-acyclic chain substituted thymine derivatives

artículo científico publicado en 2005

Antiviral and immunomodulatory activity of the metal chelator ethylenediaminedisuccinic acid against cytomegalovirus in vitro and in vivo

artículo científico publicado en 2002

Antiviral effect of the nucleoside analogue cidofovir in the context of sexual transmission of a gammaherpesvirus in mice

scholarly article by Caroline Zeippen et al published 16 May 2018 in Journal of Antimicrobial Chemotherapy

Antiviral enantiomeric preference for 5'-noraristeromycin.

artículo científico publicado en 1994

Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines

artículo científico publicado en 2005

Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses

artículo científico publicado en 2006

Basic chemokine-derived glycosaminoglycan binding peptides exert antiviral properties against dengue virus serotype 2, herpes simplex virus-1 and respiratory syncytial virus.

artículo científico publicado en 2015

Bicyclic anti-VZV nucleosides: thieno analogues bearing an alkylphenyl side chain have reduced antiviral activity

artículo científico publicado en 2004

Bicyclic furo pyrimidine nucleosides with aryloxyphenyl and halophenyl substituted side chains as potent and selective varicella-zoster virus inhibitors

artículo científico publicado en 2001

Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of a terminal halogen substitution in the side-chain.

artículo científico publicado en 2000

Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of terminal unsaturation in the side chain

artículo científico publicado en 2001

Bicyclic nucleoside inhibitors of Varicella-Zoster virus: the effect of branching in the p-alkylphenyl side chain

artículo científico publicado en 2005

Bicyclic nucleoside inhibitors of varicella-zoster virus (VZV): effect of terminal unsaturation in the side-chain

artículo científico publicado en 2001

Bicyclic nucleoside inhibitors of varicella-zoster virus modified on the sugar moiety: 3' and 5' derivatives.

artículo científico publicado en 2004

Bicyclic nucleoside inhibitors of varicella-zoster virus: 5'-chloro and 3'-chloro derivatives

artículo científico publicado en 2003

Bicyclic nucleoside inhibitors of varicella-zoster virus: synthesis and biological evaluation of 2',3'-dideoxy-3'-fluoro and 2'-deoxy-xylo derivatives

artículo científico publicado en 2003

Broad-spectrum antiviral activity and mechanism of antiviral action of the fluoroquinolone derivative K-12.

artículo científico publicado en 1998

CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor

artículo científico publicado en 2002

CRISPR/Cas9 Editing of the Polyomavirus Tumor Antigens Inhibits Merkel Cell Carcinoma Growth In Vitro

scientific article published on 28 August 2019

Camelpox virus

artículo científico

Carbocyclic 5'-nor "reverse" fleximers. Design, synthesis, and preliminary biological activity

scientific article published on July 2011

Cell-dependent interference of a series of new 6-aminoquinolone derivatives with viral (HIV/CMV) transactivation

artículo científico publicado en 2005

Characterization of Cowpox Virus (CPV) Mutants Arising under Pressure with Different Acyclic Nucleoside Phosphonates

scientific article published in 2009

Characterization of herpes simplex virus type 1 thymidine kinase mutants selected under a single round of high-dose brivudin

artículo científico publicado en 2005

Chemotherapy of varicella zoster virus infections.

artículo científico publicado en 1994

Cidofovir Activity against Poxvirus Infections ⬇️

artículo científico publicado el 22 de diciembre de 2010

Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms

scientific article published on 16 June 2016

Cidofovir resistance in vaccinia virus is linked to diminished virulence in mice

artículo científico publicado en 2006

Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage

artículo científico publicado en 2013

Cidofovir treatment improves the pathology caused by the growth of human papillomavirus-positive cervical carcinoma xenografts in athymic nude mice

artículo científico publicado en 2012

Cidofovir, a new approach for the treatment of cervix intraepithelial neoplasia grade III (CIN III)

artículo científico publicado en 2000

Cidofovir: clinical experience and future perspectives on an acyclic nucleoside phosphonate analog of cytosine in the treatment of refractory and premalignant HPV-associated anal lesions

artículo científico publicado en 2009

Comparative activity of selected antiviral compounds against clinical isolates of human cytomegalovirus

artículo científico publicado en 1991

Comparative activity of selected antiviral compounds against clinical isolates of varicella-zoster virus

artículo científico publicado en 1995

Comparative activity of various compounds against clinical strains of herpes simplex virus

artículo científico publicado en 1992

Comparison of membrane affinity-based method with size-exclusion chromatography for isolation of exosome-like vesicles from human plasma

artículo científico publicado en 2018

Conservation of antiviral activity and improved selectivity in PMEO-DAPym upon pyrimidine to triazine scaffold hopping

artículo científico publicado en 2015

Correction: Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products

artículo científico publicado en 2017

Cross-Metathesis Mediated Synthesis of New Acyclic Nucleoside Phosphonates

scientific article published on 01 January 2007

Current acquisitions in antiviral drugs (anti-HIV)

artículo científico publicado el 1 de julio de 1992

DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions.

artículo científico publicado en 2007

Desferrioxamine enhances AIDS-associated Kaposi's sarcoma tumor development in a xenograft model

artículo científico publicado en 2002

Design, Synthesis and Biological Evaluation of Novel Acyclovir ProTides

scientific article published in 2008

Design, Synthesis and Evaluation of Novel Anti-VZV BCNAs

scientific article published in 2008

Design, Synthesis, and Antiviral Activity of Novel Ribonucleosides of 1,2,3-Triazolylbenzyl-aminophosphonates

artículo científico publicado en 2015

Design, Synthesis, and Molecular Docking Studies of a Conjugated Thiadiazole-Thiourea Scaffold as Antituberculosis Agents

artículo científico publicado en 2016

Design, Synthesis, and the Biological Evaluation of a New Series of Acyclic 1,2,3-Triazole Nucleosides

artículo científico publicado en 2017

Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues

artículo científico publicado en 2015

Design, synthesis and antiviral evaluation of novel acyclic phosphonate nucleotide analogs with triazolo[4,5-b]pyridine, imidazo[4,5-b]pyridine and imidazo[4,5-b]pyridin-2(3H)-one systems

scientific article published on 25 September 2019

Design, synthesis and biological evaluation of 2'-deoxy-2',2'-difluoro-5-halouridine phosphoramidate ProTides

artículo científico publicado en 2011

Design, synthesis and preliminary antiviral screening of new N-phenylpyrazole and dihydroisoxazole derivatives

article

Design, synthesis, antiviral and cytostatic activity of ω-(1H-1,2,3-triazol-1-yl)(polyhydroxy)alkylphosphonates as acyclic nucleotide analogues

artículo científico publicado en 2014

Development of a Model for the Study of Antivirals Against Molluscum Contagiosum Virus (MCV)

artículo científico publicado en 2008

Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine

artículo científico publicado en 1993

Dihydropyrimidinone/1,2,3-triazole hybrid molecules: Synthesis and anti-varicella-zoster virus (VZV) evaluation

scholarly article by Hanane Kaoukabi et al published July 2018 in European Journal of Medicinal Chemistry

Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly lipophilic bicyclic nucleoside analogues

artículo científico publicado en 2011

Discovery of a new family of inhibitors of human cytomegalovirus (HCMV) based upon lipophilic alkyl furano pyrimidine dideoxy nucleosides: action via a novel non-nucleosidic mechanism.

artículo científico publicado en 2004

Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymerase

artículo científico publicado en 2016

Drug targets in cytomegalovirus infection

artículo científico publicado en 2009

Dual anti-HSV and anti-HIV activity of the lantibiotic Labyrinthopeptin A1

article

Dual infection with polyomavirus BK and acyclovir-resistant herpes simplex virus successfully treated with cidofovir in a bone marrow transplant recipient

artículo científico publicado en 2007

Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)-guanine in the treatment of intracerebral murine cytomegalovirus infections in immunocompetent and immunodeficient mice

artículo científico publicado en 1993

Emergence of cowpox: study of the virulence of clinical strains and evaluation of antivirals

artículo científico publicado en 2013

Emerging drugs for varicella-zoster virus infections ⬇️

artículo científico publicado el 24 de junio de 2011

Emimycin and its nucleoside derivatives: Synthesis and antiviral activity

artículo científico publicado en 2017

Epithelial raft cultures for investigations of virus growth, pathogenesis and efficacy of antiviral agents.

scientific article published on 31 October 2009

Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity

artículo científico publicado en 2007

Evaluation of novel acyclic nucleoside phosphonates against human and animal gammaherpesviruses revealed an altered metabolism of cyclic prodrugs upon Epstein-Barr virus reactivation in P3HR-1 cells

artículo científico publicado en 2013

Evaluation of novel phosphoramidate ProTides of the 2'-fluoro derivatives of a potent anti-varicella zoster virus bicyclic nucleoside analogue.

artículo científico publicado en 2010

Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs

artículo científico publicado en 2017

Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs

scholarly article by Elisa Pileggi published in July 2018

Exploring the purine core of 3'-C-ethynyladenosine (EAdo) in search of novel nucleoside therapeutics

artículo científico publicado en 2016

Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products

artículo científico publicado en 2017

Flow cytometric method for the detection of gpI antigens of varicella zoster virus and evaluation of anti-VZV agents

artículo científico publicado en 1992

Fluorescence-based antiviral assay for the evaluation of compounds against vaccinia virus, varicella zoster virus and human cytomegalovirus

artículo científico publicado en 2008

From 1-acyl-beta-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors.

artículo científico publicado en 2005

From β-Amino-γ-sultone to Unusual Bicyclic Pyridine and Pyrazine Heterocyclic Systems: Synthesis and Cytostatic and Antiviral Activities

article

Furano pyrimidines as novel potent and selective anti-VZV agents

artículo científico publicado en 2001

GS-9191 is a novel topical prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl)guanine with antiproliferative activity and possible utility in the treatment of human papillomavirus lesions.

artículo científico publicado en 2009

Halophenyl furanopyrimidines as potent and selective anti-VZV agents

artículo científico publicado en 2003

Herpes simplex virus drug-resistance: new mutations and insights

artículo científico

Herpesvirus infections in immunocompromised patients

artículo científico publicado en 1995

Heterogeneity and evolution of thymidine kinase and DNA polymerase mutants of herpes simplex virus type 1: implications for antiviral therapy

artículo científico publicado en 2013

Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates

artículo científico publicado en 2018

Highly potent and selective inhibition of varicella-zoster virus by bicyclic furopyrimidine nucleosides bearing an aryl side chain

artículo científico publicado en 2000

Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma

artículo científico publicado en 2015

Identification of Bicyclic Sulfone Inhibitors of HHV-6 Targeting the HHV-6 U77 Helicase

artículo científico publicado en 2011

Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor

artículo científico publicado en 2016

Identification of the Type of Cells Responsible for Transfer of Herpes Simplex Virus (HSV) and Vaccinia Virus (VACV) Infection to Epithelial Cells Grown in 3D

scientific article published in 2009

Imbalance in Production of Cytokines by Bone Marrow Stromal Cells following Cytomegalovirus Infection

article

Imidazothiadiazine dioxides: synthesis and antiviral activity

artículo científico publicado en 1999

In Vitro -Selected Drug-Resistant Varicella-Zoster Virus Mutants in the Thymidine Kinase and DNA Polymerase Genes Yield Novel Phenotype-Genotype Associations and Highlight Differences between Antiherpesvirus Drugs ⬇️

artículo científico publicado el 21 de diciembre de 2011

In vitro evaluation of the anti-orf virus activity of alkoxyalkyl esters of CDV, cCDV and (S)-HPMPA.

artículo científico publicado en 2006

In vitro sensitivity of Kaposi's sarcoma cells to various chemotherapeutic agents including acyclic nucleoside phosphonates

artículo científico publicado en 1999

In vivo antiherpesvirus activity of N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine

artículo científico publicado en 1995

Inactivity of the bicyclic pyrimidine nucleoside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymidine kinase

artículo científico publicado en 2004

Influence of 2-substituent on the activity of imidazo[1,2-a] pyridine derivatives against human cytomegalovirus

artículo científico publicado en 2002

Influence of 6 or 8-substitution on the antiviral activity of 3-phenethylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (HCMV) and varicella-zoster virus (VZV).

artículo científico publicado en 2007

Influence of 6- or 8-substitution on the antiviral activity of 3-arylalkylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (CMV) and varicella-zoster virus (VZV): part II.

artículo científico publicado en 2008

Inhibition of vaccinia virus replication by two small interfering RNAs targeting B1R and G7L genes and their synergistic combination with cidofovir

artículo científico publicado en 2009

Inhibitory activities of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate simian virus 40 strains

artículo científico publicado en 2007

Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro

artículo científico publicado en 1990

Insights into the mechanism of action of cidofovir and other acyclic nucleoside phosphonates against polyoma- and papillomaviruses and non-viral induced neoplasia.

artículo científico publicado en 2014

Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine

artículo científico publicado en 2008

Intravesical instillation of cidofovir in the treatment of hemorrhagic cystitis caused by adenovirus type 11 in a bone marrow transplant recipient

artículo científico publicado en 2004

Introduction to the Special Issue dedicated to Prof. Erik De Clercq for reaching the Professor Emeritus status at the Katholieke Universiteit Leuven

artículo científico publicado en 2006

Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice

artículo científico publicado en 2018

Iron chelators inhibit the growth and induce the apoptosis of Kaposi's sarcoma cells and of their putative endothelial precursors.

artículo científico publicado en 2000

Iron withdrawal strategies fail to prevent the growth of SiHa-induced tumors in mice

artículo científico publicado en 2003

Is the Large T Antigen a Target for the Inhibition of SV40 Replication?

artículo científico publicado en 2010

Isoxazolidine Conjugates of N3-Substituted 6-Bromoquinazolinones—Synthesis, Anti-Varizella-Zoster Virus, and Anti-Cytomegalovirus Activity

artículo científico publicado en 2018

KAY-2-41, a novel nucleoside analogue inhibitor of orthopoxviruses in vitro and in vivo

scientific article published on 14 October 2013

KSHV targeted therapy: an update on inhibitors of viral lytic replication

artículo científico publicado en 2014

Kaposi's sarcoma, oncogenic viruses, and iron.

artículo científico publicado en 2001

Kaposi's sarcoma-associated herpesvirus: the role of lytic replication in targeted therapy

artículo científico publicado en 2015

Lignosulfonic acid exhibits broad-spectrum anti-HIV and anti-HSV activity and has potential for microbicidal applications

article

Local treatment of HPV-induced skin lesions by Cidofovir

artículo científico publicado en 2002

Lymphocyte-independent pathways underlie the pathogenesis of murine cytomegalovirus-associated secondary hemophagocytic lymphohistiocytosis.

artículo científico publicado en 2017

Lytic viral replication and immunopathology in a cytomegalovirus-induced mouse model of secondary hemophagocytic lymphohistiocytosis

artículo científico publicado en 2017

Mechanism of antiviral drug resistance of vaccinia virus: identification of residues in the viral DNA polymerase conferring differential resistance to antipoxvirus drugs

artículo científico publicado en 2008

Meningoradiculoneuritis due to acyclovir-resistant varicella-zoster virus in a patient with AIDS.

artículo científico publicado en 1993

Metabolic and pharmacological characteristics of the bicyclic nucleoside analogues (BCNAs) as highly selective inhibitors of varicella-zoster virus (VZV).

artículo científico publicado en 2003

Methods in Anti-HCMV Research

artículo científico publicado en 2000

Methyl-2-arylidene hydrazinecarbodithioates: synthesis and biological activity

article

Mouse Cytomegalovirus Infection in BALB/c Mice Resembles Virus-Associated Secondary Hemophagocytic Lymphohistiocytosis and Shows a Pathogenesis Distinct from Primary Hemophagocytic Lymphohistiocytosis

artículo científico publicado en 2016

Multidrug-resistant cytomegalovirus infection in a pediatric stem cell transplantation patient.

artículo científico publicado en 2016

Mutations conferring resistance to viral DNA polymerase inhibitors in camelpox virus give different drug-susceptibility profiles in vaccinia virus.

artículo científico publicado en 2012

Mutations in adenosine deaminase-like (ADAL) protein confer resistance to the antiproliferative agents N6-cyclopropyl-PMEDAP and GS-9219.

artículo científico publicado en 2013

N(4)-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: chemistry and antiviral activity

artículo científico publicado en 2014

N1,N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase.

artículo científico publicado en 2013

New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation

artículo científico publicado en 2002

New Derivatives of 5-Substituted Uracils: Potential Agents with a Wide Spectrum of Biological Activity

artículo científico publicado en 2022

New Isoxazolidine-Conjugates of Quinazolinones-Synthesis, Antiviral and Cytostatic Activity.

artículo científico publicado en 2016

New neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents

artículo científico publicado en 1992

New neplanocin analogues. 6. Synthesis and potent antiviral activity of 6'-homoneplanocin A1.

artículo científico publicado en 1996

New neplanocin analogues. 7. Synthesis and antiviral activity of 2-halo derivatives of neplanocin A.

artículo científico publicado en 1996

New prodrugs of Adefovir and Cidofovir

artículo científico publicado en 2011

New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity

artículo científico publicado en 2017

New treatments for genital herpes

article

New treatments for genital herpes

artículo científico publicado en 2002

Next-generation treatment strategies for human papillomavirus-related head and neck squamous cell carcinoma: where do we go?

artículo científico publicado en 2011

No apparent effect of cidofovir in epidermodysplasia verruciformis

scientific article published on 01 February 2000

Non-nucleoside structures retain full anti-HCMV potency of the dideoxy furanopyrimidine family.

artículo científico publicado en 2004

Nosocomial bacteremia caused by Bacillus species.

artículo científico publicado en 1988

Novel Carbocyclic Nucleosides Containing A Cyclobutyl Ring. Guanosine and Adenosine Analogues ⬇️

artículo científico publicado el 1 de julio de 1998

Novel Carbocyclic Nucleosides Containing a Cyclopentyl Ring. Adenosine and Uridine Analogues

scientific article published on 01 August 1997

Novel Isoxazolidine and γ-Lactam Analogues of Homonucleosides

artículo científico publicado en 2019

Novel Therapeutics for Epstein⁻Barr Virus

scientific article published on 12 March 2019

Novel [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]- 3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2" -dioxide) derivatives with anti-HIV-1 and anti-human-cytomegalovirus activity.

artículo científico publicado en 2005

Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates

artículo científico publicado en 2011

Novel aryl substituted bicyclic furo nucleosides as extremely potent and selective anti-VZV agents

artículo científico publicado en 2001

Novel bicyclic furanopyrimidines with dual anti-VZV and -HCMV activity

artículo científico publicado en 2003

Novel halogenated 3-deazapurine, 7-deazapurine and alkylated 9-deazapurine derivatives of L-ascorbic or imino-L-ascorbic acid: Synthesis, antitumour and antiviral activity evaluations.

artículo científico publicado en 2015

Novel inhibitors of human CMV.

artículo científico publicado en 2008

Novel isoxazolidine analogues of homonucleosides and homonucleotides

artículo científico publicado en 2016

Novel non-nucleoside human cytomegalovirus inhibitors based upon TSAO nucleoside derivatives: structure-activity relationships

artículo científico publicado en 2007

Novel potential agents for human cytomegalovirus infection: synthesis and antiviral activity evaluation of benzothiadiazine dioxide acyclonucleosides

artículo científico publicado en 1999

Novel sulfated polysaccharides: dissociation of anti-human immunodeficiency virus activity from antithrombin activity.

artículo científico publicado en 1990

Orf nodules and immunosuppression: a case report and review of therapeutics

artículo científico publicado en 2015

Organotypic epithelial raft cultures as a model for evaluating compounds against alphaherpesviruses

artículo científico publicado en 2005

Ovine skin organotypic cultures applied to the ex vivo study of orf virus infection

artículo científico publicado en 2005

Palladium-catalyzed synthesis of (E)-5-(2-acylvinyl)-2′-deoxyuridines and their antiviral and cytotoxic activities

artículo científico publicado en 1995

Papillomavirus and treatment

artículo científico publicado en 2006

Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro

artículo científico publicado en 1991

Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro

artículo científico publicado en 1996

Persistent primary cytomegalovirus infection in a kidney transplant recipient: Multi-drug resistant and compartmentalized infection leading to graft loss

scientific article published on 15 June 2019

Phase II double-blind, placebo-controlled study of the safety and efficacy of cidofovir topical gel for the treatment of patients with human papillomavirus infection

artículo científico publicado en 2001

Phosphonoamidate prodrugs of C5-substituted pyrimidine acyclic nucleosides for antiviral therapy.

artículo científico publicado en 2017

Phosphonylated 8-Azahypoxantines as Acyclic Nucleotide Analogs

Phosphonylated Acyclic Guanosine Analogues with the 1,2,3-Triazole Linker.

artículo científico publicado en 2015

Polyanion inhibitors of HIV and other viruses. 7. Polyanionic compounds and polyzwitterionic compounds derived from cyclodextrins as inhibitors of HIV transmission.

artículo científico publicado en 1998

Polyanion inhibitors of human immunodeficiency virus and other viruses. 1. Polymerized anionic surfactants.

artículo científico publicado en 1995

Polyomavirus infection in pediatric renal transplant recipients: evaluation using a quantitative real-time PCR technique

artículo científico publicado en 2004

Polysulfonates derived from metal thiolate complexes as inhibitors of HIV-1 and various other enveloped viruses in vitro.

artículo científico publicado en 2002

Potent and selective inhibition of varicella-zoster virus (VZV) by nucleoside analogues with an unusual bicyclic base

artículo científico publicado en 1999

Potent, selective and cell-mediated inhibition of human herpesvirus 6 at an early stage of viral replication by the non-nucleoside compound CMV423.

artículo científico publicado en 2004

Practical and efficient synthesis of pyrano[3,2-c]pyridone, pyrano[4,3-b]pyran and their hybrids with nucleoside as potential antiviral and antileishmanial agents

artículo científico publicado en 2010

Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus

artículo científico publicado en 2007

Preparation of acyclo nucleoside phosphonate analogues based on cross-metathesis

article

Pridine Oxide Derivatives: Structure‐Activity Relationship for Inhibition of Human Immunodeficiency Virus and Cytomegalovirus Replication in Cell Culture

artículo científico publicado en 2002

ProTides of N-(3-(5-(2'-deoxyuridine))prop-2-ynyl)octanamide as potential anti-tubercular and anti-viral agents.

artículo científico publicado en 2014

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

artículo científico publicado en 1988

Reduced tumorigenicity and pathogenicity of cervical carcinoma SiHa cells selected for resistance to cidofovir

artículo científico publicado en 2013

Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1

artículo científico publicado en 2016

Role of cidofovir in the treatment of DNA virus infections, other than CMV infections, in immunocompromised patients.

artículo científico publicado en 2002

S-Adenosyl-L-homocysteine Hydrolase Inhibitors as Anti-Viral Agents: 5′-Deoxyaristeromycin

article

ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping

artículo científico publicado en 2015

Safety and tolerance of cidofovir as a 2% gel for local application in high-grade cervical intraepithelial neoplasia: A phase 1 investigation

artículo científico publicado en 2018

Selection and Characterization of (S)-1-[3-Hydroxy-2-(Phosphonomethoxypropyl)-2,6-Diaminopurine [HPMPDAP] Resistant Camelpox Viruses

article

Selective inhibition of human cytomegalovirus DNA synthesis by (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-HPMPC] and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG).

artículo científico publicado en 1990

Sensitive, reproducible and convenient fluorometric assay for the in vitro evaluation of anticytomegalovirus agents

artículo científico publicado en 1991

Sequestration of human cytomegalovirus by human renal and mammary epithelial cells

artículo científico publicado en 2014

Skin mild hypoxia enhances killing of UVB-damaged keratinocytes through reactive oxygen species-mediated apoptosis requiring Noxa and Bim.

artículo científico publicado en 2012

Solvent-free synthesis of pyrimidine nucleoside-aminophosphonate hybrids and their biological activity evaluation

artículo científico publicado en 2010

Sonication-Assisted Synthesis of(E)-2-Methyl-but-2-enyl Nucleoside Phosphonate Prodrugs

Specific inhibition of orthopoxvirus replication by a small interfering RNA targeting the D5R gene

artículo científico publicado en 2008

Specific targeting of the F13L protein by ST-246 affects orthopoxvirus production differently

artículo científico publicado en 2008

Spectrum of activity and mechanisms of resistance of various nucleoside derivatives against gammaherpesviruses

artículo científico publicado en 2014

Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base

artículo científico publicado en 1999

Structure–Activity Relationship of a Novel Class of Aglycoristocetin Derivatives with Potent and Broad Activity Against Influenza Viruses

artículo científico publicado en 2009

Study of camelpox virus pathogenesis in athymic nude mice

artículo científico publicado en 2011

Successful kinase bypass with new acyclovir phosphoramidate prodrugs

artículo científico publicado en 2008

Successful treatment of a squamous papilloma of the hypopharynx-esophagus by local injections of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine.

artículo científico publicado en 1995

Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).

artículo científico publicado en 1994

Successful treatment of recurrent vulvar intraepithelial neoplasia resistant to interferon and isotretinoin with cidofovir.

artículo científico publicado en 2001

Successful use of intralesional and intravenous cidofovir in association with indole-3-carbinol in an 8-year-old girl with pulmonary papillomatosis

artículo científico publicado en 2005

Sulfated polymers inhibit the interaction of human cytomegalovirus with cell surface heparan sulfate

article

Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus

artículo científico publicado en 1988

Susceptibilities of several clinical varicella-zoster virus (VZV) isolates and drug-resistant VZV strains to bicyclic furano pyrimidine nucleosides

artículo científico publicado en 2005

Synthesis and Antiviral Activities of Some Novel Carbocyclic Nucleosides

Synthesis and Antiviral Activity of Acyclic Nucleotide Analogues Derived from 6-(Aminomethyl)purines and Purine-6-carboxamidines

Synthesis and Antiviral Activity of Various N4-Acyl Derivatives of Cidofovir and its 5-Azacytosine Counterpart, 1-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]-5-Azacytosine

artículo científico publicado en 2008

Synthesis and Antiviral and Cytostatic Activities of Carbocyclic Nucleosides Incorporating a Modified Cyclobutane Ring

artículo científico publicado en 1999

Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV).

artículo científico publicado en 2017

Synthesis and Bioactivity of Novel Trisubstituted Triazole Nucleosides.

artículo científico publicado en 2016

Synthesis and Biological Evaluation of 1,2-Disubstituted Carbonucleosides of 6-Substituted Purine and 8-Azapurine

artículo científico publicado en 1999

Synthesis and Biological Evaluation of Acyclic Nucleotide Analogues of Bicyclic Pyrimidine Bases

scientific article published in 2009

Synthesis and Evaluations of "1,4-Triazolyl Combretacoumarins" and Desmethoxy Analogues

scientific article published on 07 August 2019

Synthesis and SAR studies on azetidine-containing dipeptides as HCMV inhibitors

article

Synthesis and anti-HCMV activity of 1-[ω-(phenoxy)alkyl]uracil derivatives and analogues thereof

artículo científico publicado en 2013

Synthesis and anti-HCMV activity of 1-acyl-beta-lactams and 1-acylazetidines derived from phenylalanine.

artículo científico publicado en 2004

Synthesis and anti-HIV-1 and anti-HCMV activity of 1-substituted 3-(3,5-dimethylbenzyl)uracil derivatives

artículo científico publicado en 2006

Synthesis and anti-HSV activity of tricyclic penciclovir and hydroxybutylguanine derivatives

scientific article published on 02 February 2019

Synthesis and anti-VZV activity of 6-heteroaryl derivatives of tricyclic acyclovir and 9-{[cis-1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl}guanine analogues

artículo científico publicado en 2009

Synthesis and anti-herpes activity of 5-trifluorovinyl-2′-deoxyuridine

artículo científico publicado en 1992

Synthesis and anti-herpetic activity of phosphoramidate ProTides

artículo científico publicado en 2013

Synthesis and anti-varicella-zoster virus activity of some novel bicyclic nucleoside inhibitors: effect of enhanced aqueous solubility

artículo científico publicado en 2000

Synthesis and antiherpes virus activity of 1,5-anhydrohexitol nucleosides.

artículo científico publicado en 1993

Synthesis and antiviral activities of 3-aralkylthiomethylimidazo[1,2-b]pyridazine derivatives

artículo científico publicado en 2003

Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety

artículo científico publicado en 2012

Synthesis and antiviral activity of 1,3-disubstituted uracils against HIV-1 and HCMV.

artículo científico publicado en 2003

Synthesis and antiviral activity of 1-substituted 3-(3,5-dimethylbenzyl)uracil against HIV-1.

artículo científico publicado en 2004

Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2-(phosphonomethoxy)ethoxy]pyrimidine and related compounds

artículo científico publicado en 2004

Synthesis and antiviral activity of 3-substituted imidazo[1,2-a]pyridines

article

Synthesis and antiviral activity of 5-heteroaryl-substituted 2'-deoxyuridines

artículo científico publicado en 1991

Synthesis and antiviral activity of 5-thien-2-yl-2'-deoxyuridine analogues.

artículo científico publicado en 1993

Synthesis and antiviral activity of 6-benzoyl-benzoxazolin-2-one and 6-benzoyl-benzothiazolin-2-one derivatives

artículo científico publicado en 1999

Synthesis and antiviral activity of acyclic nucleosides with a 3(S),5-dihydroxypentyl or 4(R)-methoxy-3(S),5-dihydroxypentyl side chain

artículo científico publicado en 1992

Synthesis and antiviral activity of new pyrazole and thiazole derivatives.

artículo científico publicado en 2009

Synthesis and antiviral activity of the carbocyclic analogue of the highly potent and selective anti-VZV bicyclo furano pyrimidines

artículo científico publicado en 2007

Synthesis and antiviral activity of three pyrazole analogues of distamycin A.

artículo científico publicado en 1994

Synthesis and antiviral and cytostatic evaluations of the new C-5 substituted pyrimidine and furo[2,3-d]pyrimidine 4',5'-didehydro-L-ascorbic acid derivatives

artículo científico publicado en 2007

Synthesis and antiviral evaluation of 6-(alkyl-heteroaryl)furo[2,3-d]pyrimidin-2(3H)-one nucleosides and analogues with ethynyl, ethenyl, and ethyl spacers at C6 of the furopyrimidine core

artículo científico publicado en 2007

Synthesis and antiviral evaluation of C5-substituted-(1,3-diyne)-2'-deoxyuridines.

artículo científico publicado en 2012

Synthesis and antiviral evaluation of bis(POM) prodrugs of (E)-[4′-phosphono-but-2′-en-1′-yl]purine nucleosides

article

Synthesis and antiviral evaluation of cyclopentyl nucleoside phosphonates

artículo científico publicado en 2018

Synthesis and antiviral evaluation of phosphoramidate derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine

artículo científico publicado en 2001

Synthesis and antiviral evaluation of some 3'-fluoro bicyclic nucleoside analogues

artículo científico publicado en 2004

Synthesis and antiviral properties of (+/-)-5'-noraristeromycin and related purine carbocyclic nucleosides. A new lead for anti-human cytomegalovirus agent design

artículo científico publicado en 1992

Synthesis and biological evaluation of 5-(alkyn-1-yl)-1-(p-toluenesulfonyl)uracil derivatives

article

Synthesis and biological evaluation of 6-(alkyn-1-yl)furo[2,3-d]pyrimidin-2(3H)-one base and nucleoside derivatives

artículo científico publicado en 2006

Synthesis and biological evaluation of N- and O-alkylated bicyclic furanopyrimidines as non-nucleosidic inhibitors of human cytomegalovirus.

artículo científico publicado en 2005

Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2'-deoxy nucleoside analogues

artículo científico publicado en 2012

Synthesis and biological evaluation of acyclic 3-[(2-hydroxyethoxy)methyl] analogues of antiviral furo- and pyrrolo[2,3-d]pyrimidine nucleosides

artículo científico publicado en 2005

Synthesis and biological evaluation of acyclic nucleotide analogues with a furo[2,3-d]pyrimidin-2(3H)-one base

Synthesis and biological properties of C-2 triazolylinosine derivatives

artículo científico publicado en 2012

Synthesis and broad spectrum antiviral evaluation of bis(POM) prodrugs of novel acyclic nucleosides

artículo científico publicado en 2013

Synthesis and the Biological Activity of Phosphonylated 1,2,3-Triazolenaphthalimide Conjugates.

artículo científico publicado en 2016

Synthesis of 3',4'-difluoro-3'-deoxyribonucleosides and its evaluation of the biological activities: discovery of a novel type of anti-HCV agent 3',4'-difluorocordycepin

artículo científico publicado en 2014

Synthesis of O2- and N3-(2-Phosphonomethoxy)ethyl Derivatives of 6-Phenyl- and 6-Pyridinyl-5-azacytosine

article

Synthesis of a 3'-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides

Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents

artículo científico publicado en 2010

Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2'-deoxyuridines and their antiviral evaluation

artículo científico publicado en 2010

Synthesis of triterpenoid triazine derivatives from allobetulone and betulonic acid with biological activities.

artículo científico publicado en 2014

Synthesis of unusual bicyclic nucleosides bearing an unsaturated side-chain, as potential inhibitors of varicella-zoster virus (VZV).

artículo científico publicado en 2003

Synthesis, Anti-varicella-zoster virus and Anti-cytomegalovirus Activity of 4,5-Disubstituted 1,2,3-(1H)-Triazoles

Synthesis, Biological Evaluation, and Structure Analysis of a Series of New 1,5-Anhydrohexitol Nucleosides

article

Synthesis, X-ray crystal structure study, and cytostatic and antiviral evaluation of the novel cycloalkyl-N-aryl-hydroxamic acids.

artículo científico publicado en 2005

Synthesis, anti-varicella-zoster virus and anti-cytomegalovirus activity of quinazoline-2,4-diones containing isoxazolidine and phosphonate substructures

artículo científico publicado en 2016

Synthesis, antiviral and anticancer activity of some novel thioureas derived from N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide

artículo científico publicado en 2009

Synthesis, antiviral, cytotoxic and cytostatic evaluation of N 1-(phosphonoalkyl)uracil derivatives

artículo científico publicado en 2016

Synthesis, cytostatic and anti-HIV evaluations of the new unsaturated acyclic C-5 pyrimidine nucleoside analogues.

artículo científico publicado en 2008

Systemic cidofovir in papillomatosis

artículo científico publicado en 2001

Tecovirimat, a p37 envelope protein inhibitor for the treatment of smallpox infection.

scientific article published on March 2010

Tenofovir Activating Kinases May Impact the Outcome of HIV Treatment and Prevention

artículo científico publicado en 2015

The Low-Cost Compound Lignosulfonic Acid (LA) Exhibits Broad-Spectrum Anti-HIV and Anti-HSV Activity and Has Potential for Microbicidal Applications

artículo científico publicado en 2015

The N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine is a potent and selective inhibitor of herpesvirus replication ⬇️

artículo científico publicado el 1 de diciembre de 1994

The anti-HIV drug tenofovir, a reverse transcriptase inhibitor, also targets the herpes simplex virus (HSV) DNA polymerase

artículo científico publicado en 2017

The cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanine

artículo científico publicado en 2000

The journey towards elucidating the anti-HCMV activity of alkylated bicyclic furano pyrimidines.

artículo científico

The lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applications

artículo científico publicado en 2013

The large tumor antigen: a "Swiss Army knife" protein possessing the functions required for the polyomavirus life cycle.

artículo científico publicado en 2012

The novel L- and D-amino acid derivatives of hydroxyurea and hydantoins: synthesis, X-ray crystal structure study, and cytostatic and antiviral activity evaluations.

artículo científico publicado en 2005

The novel phosphoramidate derivatives of NSAID 3-hydroxypropylamides: synthesis, cytostatic and antiviral activity evaluations

artículo científico publicado en 2008

The novel primaquine derivatives of N-alkyl, cycloalkyl or aryl urea: synthesis, cytostatic and antiviral activity evaluations.

artículo científico publicado en 2007

Therapy for herpesvirus infections

Therapy of poxvirus infections

article

Thienothiadiazine 2,2-dioxide acyclonucleosides: synthesis and antiviral activity

artículo científico publicado en 2000

Thymidine kinase and protein kinase in drug-resistant herpesviruses: Heads of a Lernaean Hydra

artículo científico publicado en 2018

Topical cidofovir (HPMPC) is an effective adjuvant to surgical treatment of anogenital condylomata acuminata

artículo científico publicado en 2003

Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication

artículo científico publicado en 2011

Topical treatment of CIN 2+ by cidofovir: results of a phase II, double-blind, prospective, placebo-controlled study.

artículo científico publicado en 2009

Toward the discovery of dual HCMV-VZV inhibitors: Synthesis, structure activity relationship analysis, and cytotoxicity studies of long chained 2-uracil-3-yl-N-(4-phenoxyphenyl)acetamides.

artículo científico publicado en 2015

Treatment of a bowenoid papulosis of the penis with local applications of cidofovir in a patient with acquired immunodeficiency syndrome

artículo científico publicado en 2001

Treatment of anogenital papillomavirus infections with an acyclic nucleoside phosphonate analogue

artículo científico publicado en 1995

Treatment of intraurethral condylomata acuminata with surgery and cidofovir instillations in two immunocompromised patients and review of the literature

article

Treatment of severe laryngeal papillomatosis with intralesional injections of cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine].

artículo científico publicado en 1998

Tricyclic analogues of acyclovir and ganciclovir. Influence of substituents in the heterocyclic moiety on the antiviral activity.

artículo científico publicado en 1994

Tricyclic etheno analogs of PMEG and PMEDAP: Synthesis and biological activity

artículo científico publicado en 2006

Use of polymerase chain reaction for diagnosis of disseminated adenovirus infection

artículo científico publicado en 2002

Utilisation des antiviraux pour les orthopoxviroses

artículo científico publicado en 2004

Utilization of 1,3-Dioxolanes in the Synthesis of α-branched Alkyl and Aryl 9-[2-(Phosphonomethoxy)Ethyl]Purines and Study of the Influence of α-branched Substitution for Potential Biological Activity

artículo científico publicado en 2018

Varicella-Zoster Virus ORF9p Binding to Cellular Adaptor Protein Complex 1 Is Important for Viral Infectivity

artículo científico publicado en 2018

Verrucous carcinoma of the esophagus. A case report

artículo científico publicado en 2005

Viral DNA Polymerase Inhibitors

Virtual screening of acyclovir derivatives as potential antiviral agents: design, synthesis and biological evaluation of new acyclic nucleoside ProTides

artículo científico publicado en 2017

Xanthine-based acyclic nucleoside phosphonates with potent antiviral activity against varicella-zoster virus and human cytomegalovirus

artículo científico publicado en 2018

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda