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Lista de obras de Jean Langhorne

-specific atypical memory B cells are short-lived activated B cells

artículo científico publicado en 2018

10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity

A New Link between γδ T Cells and Myeloid Cells in Malaria?

artículo científico publicado en 2018

A comprehensive evaluation of rodent malaria parasite genomes and gene expression

artículo científico publicado en 2014

A dual role for B cells in Plasmodium chabaudi chabaudi (AS) infection?

artículo científico publicado en 1994

A flow cytometric method to assess antigen-specific proliferative responses of different subpopulations of fresh and cryopreserved human peripheral blood mononuclear cells

article

A freeze-dried merozoite vaccine effective against Plasmodium knowlesi malaria ⬇️

artículo científico publicado el 1 de mayo de 1977

A monoclonal antibody against a new differentiation antigen of thymocytes.

artículo científico publicado en 1983

A role for B cells in the development of T cell helper function in a malaria infection in mice

artículo científico publicado en 1998

Acquired Immunity and Vaccination in Malaria

artículo científico publicado el 1 de noviembre de 1977

Alterations of splenic architecture in malaria are induced independently of Toll-like receptors 2, 4, and 9 or MyD88 and may affect antibody affinity

artículo científico publicado en 2008

Altered response of CD4+ T cell subsets to Plasmodium chabaudi chabaudi in B cell-deficient mice

artículo científico publicado en 1993

An enhanced toolkit for the generation of knockout and marker-free fluorescent Plasmodium chabaudi

scientific article published on 17 April 2020

Analysis of T lymphocyte reactivity to complex antigen mixtures by the use of proteins coupled to latex beads

artículo científico publicado en 1990

Analysis of pir gene expression across the Plasmodium life cycle

artículo científico publicado en 2021

Antibody isotype analysis of malaria-nematode co-infection: problems and solutions associated with cross-reactivity

artículo científico publicado en 2010

Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection

artículo científico publicado en 2017

Assessing antigen-specific proliferation and cytokine responses using flow cytometry

artículo científico publicado en 2002

B and T lymphocyte attenuator restricts the protective immune response against experimental malaria

artículo científico publicado en 2011

B cell memory to 3 Plasmodium falciparum blood-stage antigens in a malaria-endemic area

artículo científico publicado en 2005

B-cell memory in malaria: Myths and realities

artículo científico publicado en 2020

Blood-stage immunity to Plasmodium chabaudi malaria following chemoprophylaxis and sporozoite immunization

artículo científico publicado en 2015

CD4 T cell responses to a variant antigen of the malaria parasite Plasmodium falciparum, erythrocyte membrane protein-1, in individuals living in malaria-endemic areas

artículo científico publicado en 2002

CD4 T cells from malaria-nonexposed individuals respond to the CD36-Binding Domain of Plasmodium falciparum erythrocyte membrane protein-1 via an MHC class II-TCR-independent pathway

artículo científico publicado en 2006

CD4 T-cell subsets in malaria: TH1/TH2 revisited

artículo científico publicado en 2014

CD4+ T cells and B cells are necessary for the transfer of protective immunity to Plasmodium chabaudi chabaudi

artículo científico publicado en 1991

CD4+T cell-dependent effector mechanisms important in the immune response to the erythrocytic stages of Plasmodium chabaudi chabaudi (AS).

artículo científico publicado en 1991

CTLA-4 blockade differentially influences the outcome of non-lethal and lethal Plasmodium yoelii infections

artículo científico publicado en 2007

Cellular responses to Plasmodium falciparum erythrocyte membrane protein-1: use of relatively conserved synthetic peptide pools to determine CD4 T cell responses in malaria-exposed individuals in Benin, West Africa

artículo científico publicado en 2002

Cellular responses to modified Plasmodium falciparum MSP119 antigens in individuals previously exposed to natural malaria infection

artículo científico publicado en 2009

Cerebral edema and cerebral hemorrhages in interleukin-10-deficient mice infected with Plasmodium chabaudi

artículo científico publicado en 2004

Characterization and gene expression analysis of the cir multi-gene family of Plasmodium chabaudi chabaudi (AS).

artículo científico publicado en 2012

Characterization of the Plasmodium Interspersed Repeats (PIR) proteins of Plasmodium chabaudi indicates functional diversity

artículo científico publicado en 2016

Characterization of the repertoire diversity of the Plasmodium falciparum stevor multigene family in laboratory and field isolates

artículo científico publicado en 2009

Chronic helminth infection does not impair immune response to malaria transmission blocking vaccine Pfs230D1-EPA/Alhydrogel® in mice

article

Classical CD11c+ dendritic cells, not plasmacytoid dendritic cells, induce T cell responses to Plasmodium chabaudi malaria

artículo científico publicado en 2009

Cloning and sequencing of a cDNA fragment from Plasmodium chabaudi chabaudi that contains repetitive sequences coding for a potentially lysine-rich aspartic acid-rich protein

artículo científico publicado en 1993

Complement contributes to protective immunity against reinfection by Plasmodium chabaudi chabaudi parasites.

artículo científico publicado en 2001

Correction to: Transcriptomes of microglia in experimental cerebral malaria in mice in the presence and absence of Type I Interferon signaling

artículo científico publicado en 2019

Correction: B and T Lymphocyte Attenuator Restricts the Protective Immune Response against Experimental Malaria

scholarly article by G. Adler et al published 5 January 2012 in Journal of Immunology

Cross-stage immunity for malaria vaccine development

artículo científico publicado en 2015

Cytokine profiles for human V gamma 9+ T cells stimulated by Plasmodium falciparum

artículo científico publicado en 1995

Cytokine responses of CD4+ T cells during a Plasmodium chabaudi chabaudi (ER) blood-stage infection in mice initiated by the natural route of infection

artículo científico publicado en 2007

Defective vaccine-induced resistance to Schistosoma mansoni in P strain mice. III. Specificity of the associated defect in cell-mediated immunity

artículo científico publicado en 1986

Dendritic cells, pro-inflammatory responses, and antigen presentation in a rodent malaria infection

artículo científico publicado en 2004

Different regions of the malaria merozoite surface protein 1 of Plasmodium chabaudi elicit distinct T-cell and antibody isotype responses

artículo científico publicado en 2001

Differential T cell responses to Plasmodium chabaudi chabaudi in peripheral blood and spleens of C57BL/6 mice during infection

artículo científico publicado en 1991

Differential requirement for cathepsin D for processing of the full length and C-terminal fragment of the malaria antigen MSP1.

artículo científico publicado en 2011

Direct activation of dendritic cells by the malaria parasite, Plasmodium chabaudi chabaudi

artículo científico publicado en 2001

Disruption of IL-21 signaling affects T cell-B cell interactions and abrogates protective humoral immunity to malaria

artículo científico publicado en 2015

Distinct kinetics of memory B-cell and plasma-cell responses in peripheral blood following a blood-stage Plasmodium chabaudi infection in mice

artículo científico publicado en 2010

Distribution of immunoglobulin isotypes in the nonspecific B-cell response induced by infection with Plasmodium chabaudi adami and Plasmodium yoelii

artículo científico publicado en 1985

Disulfide bonds in merozoite surface protein 1 of the malaria parasite impede efficient antigen processing and affect the in vivo antibody response

artículo científico publicado en 2004

Disulfide bonds in merozoite surface protein 1 of the malaria parasite impede efficient antigen processing and affect the in vivo antibody response

artículo científico publicado en 2004

Effector memory Th1 CD4 T cells are maintained in a mouse model of chronic malaria

artículo científico publicado en 2010

Epitope-specific regulation of immunoglobulin class switching in mice immunized with malarial merozoite surface proteins

artículo científico publicado en 2005

Expanding the antimalarial toolkit: Targeting host-parasite interactions

artículo científico publicado en 2016

Expansion of IgG+ B-cells during mitogen stimulation for memory B-cell ELISpot analysis is influenced by size and composition of the B-cell pool

artículo científico publicado en 2014

Expression of Fc gamma receptors on splenic T cells of mice infected with Plasmodium chabaudi adami

artículo científico publicado en 1988

Expression of GIMAP1, a GTPase of the immunity-associated protein family, is not up-regulated in malaria

scientific article published on 02 April 2009

Extramedullary myelopoiesis in malaria depends on mobilization of myeloid-restricted progenitors by IFN-γ induced chemokines

artículo científico publicado en 2013

Fc gamma receptor II dependency of enhanced presentation of major histocompatibility complex class II peptides by a B cell lymphoma.

artículo científico publicado en 1997

Follicular Helper T Cells are Essential for the Elimination of Plasmodium Infection

artículo científico publicado en 2017

Formation of interferon-gamma and tumor necrosis factor in mice during Salmonella typhimurium infection

artículo científico publicado en 1991

Frequencies of CD4+ T cells reactive with Plasmodium chabaudi chabaudi: distinct response kinetics for cells with Th1 and Th2 characteristics during infection

artículo científico publicado en 1989

Functional characterization of an LCCL-lectin domain containing protein family in Plasmodium berghei

artículo científico publicado en 2004

Functional memory B cells and long-lived plasma cells are generated after a single Plasmodium chabaudi infection in mice

artículo científico publicado en 2009

Gamma delta T cells in the peripheral blood of individuals from an area of holoendemic Plasmodium falciparum transmission.

artículo científico publicado en 1993

Gamma interferon production in endotoxin-responder and -nonresponder mice during infection.

artículo científico publicado en 1991

Gamma/Delta T Cells and Their Role in Protection Against Malaria

scholarly article by Katrien Deroost & Jean Langhorne published 20 December 2018 in Frontiers in Immunology

Gene-targeted mice lacking B cells are unable to eliminate a blood stage malaria infection.

artículo científico publicado en 1996

Genomic and transcriptomic comparisons of closely related malaria parasites differing in virulence and sequestration pattern

scholarly article by Jingwen Lin et al published 2018 in Wellcome Open Research

Germinal centre and marginal zone B cells expand quickly in a second Plasmodium chabaudi malaria infection producing mature plasma cells

scientific article published on January 2009

Heterologous Infection of Pregnant Mice Induces Low Birth Weight and Modifies Offspring Susceptibility to Malaria

artículo científico publicado en 2016

High sensitivity collisionally-activated decomposition tandem mass spectrometry on a novel quadrupole/orthogonal-acceleration time-of-flight mass spectrometer

scientific article published on 01 January 1996

Hind, N. & Langhorne, J. (2024)

artículo científico publicado en 2024

Homeostatic proliferation and IL-7R alpha expression do not correlate with enhanced T cell proliferation and protection in chronic mouse malaria

artículo científico publicado en 2011

Host immunity modulates transcriptional changes in a multigene family (yir) of rodent malaria

artículo científico publicado en 2005

Human peripheral blood gamma delta T cells respond to antigens of Plasmodium falciparum

artículo científico publicado en 1992

ICAM-1 is a key receptor mediating cytoadherence and pathology in the Plasmodium chabaudi malaria model

artículo científico publicado en 2017

IFNγ and IL-12 Restrict Th2 Responses during Helminth/Plasmodium Co-Infection and Promote IFNγ from Th2 Cells

artículo científico publicado en 2015

IL-22 Protects Against Liver Pathology and Lethality of an Experimental Blood-Stage Malaria Infection

artículo científico publicado en 2012

IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection

artículo científico publicado en 2011

Immune status of a mu, kappa transgenic mouse line. Deficient response to bacterially related antigens

artículo científico publicado en 1989

Immunity against HIV/AIDS, Malaria, and Tuberculosis during Co-Infections with Neglected Infectious Diseases: Recommendations for the European Union Research Priorities

artículo científico publicado en 2008

Immunity to malaria: more questions than answers

artículo científico publicado en 2008

Immunization of mice with Escherichia coli containing an antigen of the malaria parasite Plasmodium chabaudi chabaudi expressed in lambda gt11 induces high antibody titres

artículo científico publicado en 1994

Immunoglobulin isotype distribution of malaria-specific antibodies produced during infection with Plasmodium chabaudi adami and Plasmodium yoelii

artículo científico publicado en 1984

In vivo approaches reveal a key role for DCs in CD4+ T cell activation and parasite clearance during the acute phase of experimental blood-stage malaria

artículo científico publicado en 2015

Individual-level variations in malaria susceptibility and acquisition of clinical protection

Induction of T cell activity in athymic (nu/nu) mice infected with Trypanosoma rhodesiense

Induction of an IL7-R(+)c-Kit(hi) myelolymphoid progenitor critically dependent on IFN-gamma signaling during acute malaria

artículo científico publicado en 2010

Influence of Plasmodium chabaudi adami on the isotypic distribution of the antibody response of mice to sheep erythrocytes

artículo científico publicado en 1987

Insights into the immunopathogenesis of malaria using mouse models

artículo científico publicado en 2006

Is there a role for gamma delta T cells in malaria?

artículo científico publicado el 1 de agosto de 1992

Limiting dilution analysis of antigen-specific CD4+ T-cell responses in mice

artículo científico publicado en 2002

Limiting dilution analysis of the T cell response to Plasmodium chabaudi chabaudi in mice

artículo científico publicado en 1989

Low CD4(+) T cell responses to the C-terminal region of the malaria merozoite surface protein-1 may be attributed to processing within distinct MHC class II pathways

artículo científico publicado en 2001

Malaria infection changes the ability of splenic dendritic cell populations to stimulate antigen-specific T cells

artículo científico publicado en 2006

Malaria infection induces virus expression in human immunodeficiency virus transgenic mice by CD4 T cell-dependent immune activation

artículo científico publicado en 2001

Malaria-specific antibody responses and parasite persistence after infection of mice with Plasmodium chabaudi chabaudi

artículo científico publicado en 2007

Malaria-specific transgenic CD4(+) T cells protect immunodeficient mice from lethal infection and demonstrate requirement for a protective threshold of antibody production for parasite clearance

artículo científico publicado en 2005

Malarial anemia: of mice and men.

artículo científico publicado en 2007

Medial histocompatibility antigens.

artículo científico publicado en 1981

Memory B-cell and antibody responses induced by Plasmodium falciparum sporozoite immunization

artículo científico publicado en 2014

Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria

artículo científico publicado en 2009

Molecular approaches to malaria.

artículo científico publicado en 2004

Mosquito transmission of the rodent malaria parasite Plasmodium chabaudi

artículo científico publicado en 2012

Mosquitoes Reset Malaria Parasites

artículo científico publicado en 2015

Mouse models for erythrocytic-stage malaria

artículo científico publicado en 2002

Mouse models of blood-stage malaria infections: immune responses and cytokines involved in protection and pathology

artículo científico publicado en 2002

Neuropathogenesis of human and murine malaria

artículo científico publicado en 2010

PSLAP, a protein with multiple adhesive motifs, is expressed in Plasmodium falciparum gametocytes

artículo científico publicado en 2002

Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor alpha and exacerbated by anti-transforming growth factor beta antibodies

artículo científico publicado en 2003

Phenotypic and functional profiling of CD4 T cell compartment in distinct populations of healthy adults with different antigenic exposure

artículo científico publicado en 2013

Phenotypic characterization of splenic T cells from mice infected with Plasmodium chabaudi chabaudi

artículo científico publicado en 1993

Plasmodium chabaudi chabaudi (AS): inflammatory cytokines and pathology in an erythrocytic-stage infection in mice.

artículo científico publicado en 1998

Plasmodium chabaudi chabaudi infection in mice induces strong B cell responses and striking but temporary changes in splenic cell distribution

artículo científico publicado en 2003

Plasmodium chabaudi chabaudi: differential susceptibility of gene-targeted mice deficient in IL-10 to an erythrocytic-stage infection

artículo científico publicado en 1996

Plasmodium falciparum STEVOR proteins are highly expressed in patient isolates and located in the surface membranes of infected red blood cells and the apical tips of merozoites

artículo científico publicado en 2008

Plasmodium knowlesi in the marmoset (Callithrix jacchus).

artículo científico publicado en 1979

Priming of CD4+ T cells and development of CD4+ T cell memory; lessons for malaria

artículo científico publicado en 2006

Production of interferon-gamma during infection of mice with Plasmodium chabaudi chabaudi

artículo científico publicado en 1989

Production of murine interleukin-4 and interleukin-5 by recombinant baculovirus

artículo científico publicado en 1990

Quantitative analysis of the response of human T cell receptor Vγ9+ cells toPlasmodium falciparum

article

Quantitative studies on concanavalin A-induced, TCGF-reactive T cells. I. Correlation between proliferation and lectin-dependent cytolytic activity

scientific article published on 01 September 1981

Rapid changes in transcription profiles of the Plasmodium yoelii yir multigene family in clonal populations: lack of epigenetic memory?

artículo científico publicado en 2009

Recent advances in malaria research: new tools to understand an old enemy

scholarly article by Ana Paula Freitas do Rosario et al published August 2010 in Expert Review of Anti-infective Therapy

Recovery of an antiviral antibody response following attrition caused by unrelated infection

artículo científico publicado en 2014

Regulation of immune response by Plasmodium-infected red blood cells.

artículo científico publicado en 2005

Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance

artículo científico publicado en 2015

Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skin

artículo científico publicado en 2011

Rodent malarias: the mouse as a model for understanding immune responses and pathology induced by the erythrocytic stages of the parasite

artículo científico publicado en 2001

Role of gamma interferon during infection with Plasmodium chabaudi chabaudi.

artículo científico publicado en 1990

Role of non-H-2 antigens in the cytotoxic T cell response to allogeneic H-2.

artículo científico publicado en 1982

Roles of CD4- and CD8-bearing T lymphocytes in the immune response to the erythrocytic stages of Plasmodium chabaudi

artículo científico publicado en 1988

Screening cDNA expression libraries in lambda gt11 with a T cell hybridoma

artículo científico publicado en 1991

Sequestration and histopathology in Plasmodium chabaudi malaria are influenced by the immune response in an organ-specific manner

artículo científico publicado en 2013

Sheep gastric mucins as a source of blood-group-I and -i antigens ⬇️

artículo científico publicado en 1980

Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malaria

artículo científico publicado en 2017

Studies on the heterophile antibodies of infectious mononucleosis. I. Separation of four antibody populations, one of which contains lymphocytotoxic activity ⬇️

artículo científico publicado el 1 de diciembre de 1977

Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria.

artículo científico publicado en 2007

T Cell-Derived IL-10 Impairs Host Resistance to Mycobacterium tuberculosis Infection

artículo científico publicado en 2017

T cell control of malaria pathogenesis

artículo científico

T cell-derived IL-10 and its impact on the regulation of host responses during malaria

artículo científico

T-cell immunity to malaria

scholarly article by M.F. Good & Jean Langhorne published January 1994 in Research in Immunology

Targeted delivery of antigen processing inhibitors to antigen presenting cells via mannose receptors.

artículo científico publicado en 2010

Targeting cytotoxic T cells to antigen-specific B lymphocytes

artículo científico publicado en 1987

The Role of Animal Models for Research on Severe Malaria ⬇️

artículo científico publicado el 2 de febrero de 2012

The frequency of mutant-specific killer precursors in related and unrelated mouse strains

scientific article published on 01 October 1982

The immune response to Plasmodium chabaudi malaria in interleukin-4-deficient mice

artículo científico publicado en 1994

The immune response to the blood stages of Plasmodium in animal models

artículo científico publicado en 1994

The influence of gammadelta T cells on the CD4+ T cell and antibody response during a primary Plasmodium chabaudi chabaudi infection in mice

artículo científico publicado en 2002

The molecular interactions with helper T cells which limit antigen-specific B cell differentiation

artículo científico publicado en 1988

The pathology of Plasmodium chabaudi infection is not ameliorated by the secreted filarial nematode immunomodulatory molecule, ES-62.

artículo científico publicado en 2007

The pir multigene family of Plasmodium: antigenic variation and beyond

artículo científico publicado en 2010

The plasma concentration of the B cell activating factor is increased in children with acute malaria

artículo científico publicado en 2011

The relevance of non-human primate and rodent malaria models for humans

artículo científico publicado en 2011

The response of CD4+ T cells to Plasmodium chabaudi chabaudi

artículo científico publicado en 1989

The response of gamma delta T cells in malaria infections: a hypothesis.

artículo científico publicado en 1994

The role of CD4+ T cells in the protective immune response to Plasmodium chabaudi in vivo.

artículo científico publicado en 1990

The role of CD4+ T-cells in the immune response to Plasmodium chabaudi

artículo científico publicado en 1989

The role of the spleen in malaria

artículo científico publicado en 2012

The roles of cytokines produced in the immune response to the erythrocytic stages of mouse malarias

artículo científico publicado en 1993

The severity of malarial anaemia in Plasmodium chabaudi infections of BALB/c mice is determined independently of the number of circulating parasites

artículo científico publicado en 2008

Transcription and alternative splicing in the yir multigene family of the malaria parasite Plasmodium y. yoelii: identification of motifs suggesting epigenetic and post-transcriptional control of RNA expression

artículo científico publicado en 2007

Transcriptomes of microglia in experimental cerebral malaria in mice in the presence and absence of Type I Interferon signaling

artículo científico publicado en 2018

Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria

artículo científico publicado en 2016

Transcriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and antihelminth immunity

artículo científico publicado en 2014

Transformation of the rodent malaria parasite Plasmodium chabaudi

artículo científico publicado en 2011

Transient deficiency of dendritic cells results in lack of a merozoite surface protein 1-specific CD4 T cell response during peak Plasmodium chabaudi blood-stage infection

artículo científico publicado en 2012

Trimethoprim-Sulfamethoxazole Prophylaxis During Live Malaria Sporozoite Immunization Induces Long-Lived, Homologous, and Heterologous Protective Immunity Against Sporozoite Challenge

artículo científico publicado en 2016

Tumor necrosis factor alpha p55 receptor is important for development of memory responses to blood-stage malaria infection

artículo científico publicado en 2000

Vector transmission regulates immune control of Plasmodium virulence

artículo científico publicado en 2013

alpha beta and gamma delta T cells in the immune response to the erythrocytic stages of malaria in mice

artículo científico publicado en 1995

gammadelta T cells contribute to control of chronic parasitemia in Plasmodium chabaudi infections in mice

artículo científico publicado en 1999

gammadelta T cells in malaria infections

artículo científico publicado en 1996

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