Lista de obras - Harald Neumann - Dominio Público Uruguay

A reporter cell system for the triggering receptor expressed on myeloid cells 2 reveals differential effects of disease-associated variants on receptor signaling and activation by antibodies against the stalk region

scientific article published on 14 December 2020

A retroviral packaging cell line for pseudotype vectors based on glioma-infiltrating progenitor cells

artículo científico publicado en 2007

Activated microglia/macrophage whey acidic protein (AMWAP) inhibits NFκB signaling and induces a neuroprotective phenotype in microglia.

artículo científico publicado en 2015

Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator

artículo científico publicado en 2017

Alleviation of neurotoxicity by microglial human Siglec-11.

artículo científico publicado en 2010

Anti-inflammatory activity of low molecular weight polysialic acid on human macrophages

artículo científico publicado en 2015

Attenuated inflammatory response in triggering receptor expressed on myeloid cells 2 (TREM2) knock-out mice following stroke

artículo científico publicado en 2013

Brain endothelial PPARgamma controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro.

artículo científico publicado en 2007

Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide.

artículo científico publicado en 2005

Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene

artículo científico publicado en 2007

CCL17 exerts a neuroimmune modulatory function and is expressed in hippocampal neurons

artículo científico publicado en 2018

CXCL10 triggers early microglial activation in the cuprizone model

artículo científico publicado en 2015

Characterization of inflammatory markers and transcriptome profiles of differentially activated embryonic stem cell-derived microglia.

artículo científico publicado en 2016

Charged aerosol detector HPLC as a characterization and quantification application of biopharmaceutically relevant polysialic acid from E. coli K1

scientific article published on 01 April 2019

Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.

artículo científico publicado en 2005

Control of Innate Immunity by Sialic Acids in the Nervous Tissue

artículo científico publicado en 2020

Debris clearance by microglia: an essential link between degeneration and regeneration.

artículo científico publicado en 2009

Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease

artículo científico publicado en 2010

Engineered stem cell-derived microglia as therapeutic vehicle for experimental autoimmune encephalomyelitis

artículo científico publicado en 2013

Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis

artículo científico publicado en 2010

Generation of microglial cells from mouse embryonic stem cells.

artículo científico publicado en 2010

Hematopoietic stem cells reduce postischemic inflammation and ameliorate ischemic brain injury

artículo científico publicado en 2008

Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis

artículo científico publicado en 2018

Immune-mediated CNS damage

artículo científico publicado en 2010

Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease

artículo científico publicado en 2013

Intramembranous processing by γ-secretase regulates reverse signaling of ephrin-B2 in migration of microglia

artículo científico publicado en 2017

Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis.

artículo científico publicado en 2013

LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide.

artículo científico publicado en 2005

Licensing of myeloid cells promotes central nervous system autoimmunity and is controlled by peroxisome proliferator-activated receptor γ.

artículo científico publicado en 2012

Microglia: a cellular vehicle for CNS gene therapy.

artículo científico publicado en 2006

Microglial CD33-related Siglec-E inhibits neurotoxicity by preventing the phagocytosis-associated oxidative burst

scientific journal article

Microglial activatory (immunoreceptor tyrosine-based activation motif)- and inhibitory (immunoreceptor tyrosine-based inhibition motif)-signaling receptors for recognition of the neuronal glycocalyx.

artículo científico publicado en 2012

Microglial carbohydrate-binding receptors for neural repair.

artículo científico

Microglial clearance function in health and disease

artículo científico publicado en 2008

Microglial precursors derived from mouse embryonic stem cells.

artículo científico publicado en 2009

Neurodegeneration by activation of the microglial complement-phagosome pathway.

artículo científico publicado en 2014

Neuronal 'On' and 'Off' signals control microglia

artículo científico publicado en 2007

Neuronal injury mediated via stimulation of microglial toll-like receptor-9 (TLR9).

artículo científico

Phagocytosis-related NADPH oxidase 2 subunit gp91phox contributes to neurodegeneration after repeated systemic challenge with lipopolysaccharides

artículo científico publicado en 2020

Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina

artículo científico publicado en 2016

Polysialylation and lipopolysaccharide-induced shedding of E-selectin ligand-1 and neuropilin-2 by microglia and THP-1 macrophages

artículo científico publicado en 2016

Protective effects of microglia in multiple sclerosis.

scientific article published on 04 May 2009

Reporter cell assay for human CD33 validated by specific antibodies and human iPSC-derived microglia

artículo científico publicado en 2021

Sensing the neuronal glycocalyx by glial sialic acid binding immunoglobulin-like lectins.

artículo científico publicado en 2014

Sequential proteolytic processing of the triggering receptor expressed on myeloid cells-2 (TREM2) protein by ectodomain shedding and γ-secretase-dependent intramembranous cleavage

artículo científico publicado en 2013

Sialic acid on the neuronal glycocalyx prevents complement C1 binding and complement receptor-3-mediated removal by microglia

artículo científico publicado en 2012

Sialylation acts as a checkpoint for innate immune responses in the central nervous system

artículo científico publicado en 2020

Sialylation of neurites inhibits complement-mediated macrophage removal in a human macrophage-neuron Co-Culture System

artículo científico publicado en 2015

Siglec functions of microglia

artículo científico

Siglec-h on activated microglia for recognition and engulfment of glioma cells

artículo científico publicado en 2013

Single-use membrane adsorbers for endotoxin removal and purification of endogenous polysialic acid from Escherichia coli K1.

artículo científico publicado en 2018

Spatially pathogenic forms of tau detected in Alzheimer's disease brain tissue by fluorescence lifetime-based Förster resonance energy transfer.

artículo científico publicado en 2010

Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.

artículo científico publicado en 2006

TREM2 triggers microglial density and age-related neuronal loss

artículo científico publicado en 2018

TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis

artículo científico publicado en 2007

Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma

artículo científico publicado en 2013

Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis

artículo científico publicado en 2014

Unique transcriptome signature of mouse microglia

artículo científico publicado en 2013

Unloading kinesin transported cargoes from the tubulin track via the inflammatory c-Jun N-terminal kinase pathway.

artículo científico publicado en 2006

Lista de obras de Harald Neumann

A reporter cell system for the triggering receptor expressed on myeloid cells 2 reveals differential effects of disease-associated variants on receptor signaling and activation by antibodies against the stalk region

A retroviral packaging cell line for pseudotype vectors based on glioma-infiltrating progenitor cells

Activated microglia/macrophage whey acidic protein (AMWAP) inhibits NFκB signaling and induces a neuroprotective phenotype in microglia.

Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator

Alleviation of neurotoxicity by microglial human Siglec-11.

Anti-inflammatory activity of low molecular weight polysialic acid on human macrophages

Attenuated inflammatory response in triggering receptor expressed on myeloid cells 2 (TREM2) knock-out mice following stroke

Brain endothelial PPARgamma controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro.

Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide.

Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene

CCL17 exerts a neuroimmune modulatory function and is expressed in hippocampal neurons

CXCL10 triggers early microglial activation in the cuprizone model

Characterization of inflammatory markers and transcriptome profiles of differentially activated embryonic stem cell-derived microglia.

Charged aerosol detector HPLC as a characterization and quantification application of biopharmaceutically relevant polysialic acid from E. coli K1

Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.

Control of Innate Immunity by Sialic Acids in the Nervous Tissue

Debris clearance by microglia: an essential link between degeneration and regeneration.

Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease

Engineered stem cell-derived microglia as therapeutic vehicle for experimental autoimmune encephalomyelitis

Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis

Generation of microglial cells from mouse embryonic stem cells.

Hematopoietic stem cells reduce postischemic inflammation and ameliorate ischemic brain injury

Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis

Immune-mediated CNS damage

Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease

Intramembranous processing by γ-secretase regulates reverse signaling of ephrin-B2 in migration of microglia

Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis.

LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide.

Licensing of myeloid cells promotes central nervous system autoimmunity and is controlled by peroxisome proliferator-activated receptor γ.

Microglia: a cellular vehicle for CNS gene therapy.

Microglial CD33-related Siglec-E inhibits neurotoxicity by preventing the phagocytosis-associated oxidative burst

Microglial activatory (immunoreceptor tyrosine-based activation motif)- and inhibitory (immunoreceptor tyrosine-based inhibition motif)-signaling receptors for recognition of the neuronal glycocalyx.

Microglial carbohydrate-binding receptors for neural repair.

Microglial clearance function in health and disease

Microglial precursors derived from mouse embryonic stem cells.

Neurodegeneration by activation of the microglial complement-phagosome pathway.

Neuronal 'On' and 'Off' signals control microglia

Neuronal injury mediated via stimulation of microglial toll-like receptor-9 (TLR9).

Phagocytosis-related NADPH oxidase 2 subunit gp91phox contributes to neurodegeneration after repeated systemic challenge with lipopolysaccharides

Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina

Polysialylation and lipopolysaccharide-induced shedding of E-selectin ligand-1 and neuropilin-2 by microglia and THP-1 macrophages

Protective effects of microglia in multiple sclerosis.

Reporter cell assay for human CD33 validated by specific antibodies and human iPSC-derived microglia

Sensing the neuronal glycocalyx by glial sialic acid binding immunoglobulin-like lectins.

Sequential proteolytic processing of the triggering receptor expressed on myeloid cells-2 (TREM2) protein by ectodomain shedding and γ-secretase-dependent intramembranous cleavage

Sialic acid on the neuronal glycocalyx prevents complement C1 binding and complement receptor-3-mediated removal by microglia

Sialylation acts as a checkpoint for innate immune responses in the central nervous system

Sialylation of neurites inhibits complement-mediated macrophage removal in a human macrophage-neuron Co-Culture System

Siglec functions of microglia

Siglec-h on activated microglia for recognition and engulfment of glioma cells

Single-use membrane adsorbers for endotoxin removal and purification of endogenous polysialic acid from Escherichia coli K1.

Spatially pathogenic forms of tau detected in Alzheimer's disease brain tissue by fluorescence lifetime-based Förster resonance energy transfer.

Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.

TREM2 triggers microglial density and age-related neuronal loss

TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis

Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma

Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis

Unique transcriptome signature of mouse microglia

Unloading kinesin transported cargoes from the tubulin track via the inflammatory c-Jun N-terminal kinase pathway.