Lista de obras - Hany A. Omar - Dominio Público Uruguay

3-methyl-2-phenyl-1-substituted-indole derivatives as indomethacin analogs: design, synthesis and biological evaluation as potential anti-inflammatory and analgesic agents.

artículo científico publicado en 2015

6-Shogaol induces cell cycle arrest and apoptosis in human hepatoma cells through pleiotropic mechanisms

artículo científico publicado en 2015

A neuroprotective role of kaempferol against chlorpyrifos-induced oxidative stress and memory deficits in rats via GSK3β-Nrf2 signaling pathway

scientific article published on 13 August 2018

A novel indole-3-carbinol derivative inhibits the growth of human oral squamous cell carcinoma in vitro.

artículo científico publicado en 2010

Antiproliferative activity of cycloalkanecarboxamide derivatives possessing sulfonate or sulfamate moiety

artículo científico publicado en 2020

Antitumor effects of (S)-HDAC42, a phenylbutyrate-derived histone deacetylase inhibitor, in multiple myeloma cells.

artículo científico publicado en 2010

Antitumor effects of OSU-2S, a nonimmunosuppressive analogue of FTY720, in hepatocellular carcinoma ⬇️

artículo científico publicado el 2 de mayo de 2011

Antitumor effects of energy restriction-mimetic agents: thiazolidinediones.

artículo científico publicado en 2013

Antrodia cinnamomea boosts the anti-tumor activity of sorafenib in xenograft models of human hepatocellular carcinoma

artículo científico publicado en 2018

BACE1 inhibitors: Current status and future directions in treating Alzheimer's disease

artículo científico publicado en 2019

Bee Pollen: Current Status and Therapeutic Potential

artículo científico publicado en 2021

Caffeic Acid Phenethyl Ester: A Review of Its Antioxidant Activity, Protective Effects against Ischemia-reperfusion Injury and Drug Adverse Reactions

artículo científico publicado en 2014

Caffeic acid phenethyl ester guards against benign prostate hypertrophy in rats: Role of IGF-1R/protein kinase-B (Akt)/β-catenin signaling.

artículo científico publicado en 2018

Caffeic acid phenethyl ester protects against glucocorticoid-induced osteoporosis in vivo: Impact on oxidative stress and RANKL/OPG signals.

artículo científico publicado en 2017

Camel Milk Attenuates Rheumatoid Arthritis Via Inhibition of Mitogen Activated Protein Kinase Pathway.

artículo científico publicado en 2017

Camel's milk ameliorates TNBS-induced colitis in rats via downregulation of inflammatory cytokines and oxidative stress

artículo científico publicado en 2014

Design and synthesis of new energy restriction mimetic agents: Potent anti-tumor activities of hybrid motifs of aminothiazoles and coumarins

artículo científico publicado en 2020

Design, synthesis and analgesic/anti-inflammatory evaluation of novel diarylthiazole and diarylimidazole derivatives towards selective COX-1 inhibitors with better gastric profile.

artículo científico publicado en 2016

Design, synthesis and anticancer evaluation of novel spirobenzo[h]chromene and spirochromane derivatives with dual EGFR and B-RAF inhibitory activities.

artículo científico publicado en 2018

Design, synthesis and biological evaluation of new pyrrolidine carboxamide analogues as potential chemotherapeutic agents for hepatocellular carcinoma.

artículo científico publicado en 2017

Design, synthesis and biological evaluation of novel diphenylthiazole-based cyclooxygenase inhibitors as potential anticancer agents.

artículo científico publicado en 2014

Design, synthesis and biological evaluation of novel triaryl (Z)-olefins as tamoxifen analogues.

artículo científico publicado en 2013

Design, synthesis and biological evaluation of some novel benzothiazole/benzoxazole and/or benzimidazole derivatives incorporating a pyrazole scaffold as antiproliferative agents

artículo científico publicado en 2017

Design, synthesis and pharmacological evaluation of omeprazole-like agents with anti-inflammatory activity

artículo científico publicado en 2013

Design, synthesis, biological evaluation, and modeling studies of novel conformationally-restricted analogues of sorafenib as selective kinase-inhibitory antiproliferative agents against hepatocellular carcinoma cells

scientific article published on 04 December 2020

Diosmin protects against ethanol-induced gastric injury in rats: novel anti-ulcer actions

artículo científico publicado en 2015

Energy restriction as an antitumor target

artículo científico publicado en 2010

Energy restriction: stepping stones towards cancer therapy

artículo científico publicado en 2012

Enhancing the Anticancer Activity of Antrodia cinnamomea in Hepatocellular Carcinoma Cells via Cocultivation With Ginger: The Impact on Cancer Cell Survival Pathways

scientific article published on 18 July 2018

Gliclazide attenuates acetic acid-induced colitis via the modulation of PPARγ, NF-κB and MAPK signaling pathways

artículo científico publicado en 2020

Glutamyl cysteine dipeptide suppresses ferritin expression and alleviates liver injury in iron-overload rat model.

artículo científico publicado en 2015

Hesperidin alleviates cisplatin-induced hepatotoxicity in rats without inhibiting its antitumor activity.

artículo científico publicado en 2015

Identification of SEPTIN12 as a novel target of the androgen and estrogen receptors in human testicular cells

artículo científico publicado en 2018

Immunomodulatory MicroRNAs in cancer: targeting immune checkpoints and the tumor microenvironment

artículo científico publicado en 2019

Immunotherapy, an evolving approach for the management of triple negative breast cancer: Converting non-responders to responders.

artículo científico publicado en 2018

Iron supplementation at high altitudes induces inflammation and oxidative injury to lung tissues in rats.

artículo científico publicado en 2013

L-carnitine mitigates UVA-induced skin tissue injury in rats through downregulation of oxidative stress, p38/c-Fos signaling, and the proinflammatory cytokines.

artículo científico publicado en 2018

Mechanical and phytochemical protection mechanisms of Calligonum comosum in arid deserts.

artículo científico publicado en 2018

Modulation of cyclins, p53 and mitogen-activated protein kinases signaling in breast cancer cell lines by 4-(3,4,5-trimethoxyphenoxy)benzoic acid

artículo científico publicado en 2014

Multidirectional desymmetrization of pluripotent building block en route to diastereoselective synthesis of complex nature-inspired scaffolds

artículo científico publicado en 2018

Nicotine mediates hypochlorous acid-induced nuclear protein damage in mammalian cells

artículo científico publicado en 2014

Novel diphenylthiazole derivatives with multi-target mechanism: Synthesis, docking study, anticancer and anti-inflammatory activities.

artículo científico publicado en 2017

Novel pyrazolopyrimidine derivatives targeting COXs and iNOS enzymes; design, synthesis and biological evaluation as potential anti-inflammatory agents.

artículo científico publicado en 2014

Nuclear factor erythroid-2-related factor regulates LRWD1 expression and cellular adaptation to oxidative stress in human embryonal carcinoma cells

artículo científico publicado en 2018

OSU-2S/Sorafenib Synergistic Antitumor Combination against Hepatocellular Carcinoma: The Role of PKCδ/p53.

artículo científico publicado en 2016

OSU-A9 inhibits angiogenesis in human umbilical vein endothelial cells via disrupting Akt-NF-κB and MAPK signaling pathways.

artículo científico publicado en 2013

OSU-A9, a potent indole-3-carbinol derivative, suppresses breast tumor growth by targeting the Akt-NF-kappaB pathway and stress response signaling

artículo científico publicado en 2009

OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro

artículo científico publicado en 2014

Potential targets of energy restriction mimetic agents in cancer cells

artículo científico publicado en 2014

Pyrrolizines: Design, synthesis, anticancer evaluation and investigation of the potential mechanism of action

artículo científico publicado en 2017

Reactive oxygen species mediate Terbufos-induced apoptosis in mouse testicular cell lines via the modulation of cell cycle and pro-apoptotic proteins

artículo científico publicado en 2015

Recent advances with alkaline phosphatase isoenzymes and their inhibitors

artículo científico publicado en 2020

Sensitization of hepatocellular carcinoma cells to Apo2L/TRAIL by a novel Akt/NF-κB signalling inhibitor

artículo científico publicado en 2014

Sequencing [4 + 1]-Cycloaddition and Aza-Michael Addition Reactions: A Diastereoselective Cascade for the Rapid Access of Pyrido[2',1':2,3]/Thiazolo[2',3':2,3]imidazo[1,5-a]quinolone Scaffolds as Potential Antibacterial and Anticancer Motifs

scientific article published on 31 October 2019

Synthesis, biological evaluation, and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase

scientific article published on 25 July 2019

Synthesis, characterization and biological evaluation of novel 4'-fluoro-2'-hydroxy-chalcone derivatives as antioxidant, anti-inflammatory and analgesic agents

artículo científico publicado en 2014

Tackling Cancer Resistance by Immunotherapy: Updated Clinical Impact and Safety of PD-1/PD-L1 Inhibitors

artículo científico publicado en 2018

Tackling molecular targets beyond PD-1/PD-L1: Novel approaches to boost patients' response to cancer immunotherapy

scientific article published on 23 January 2019

Tackling the cytokine storm in COVID-19, challenges and hopes

scientific article published on 11 July 2020

Tangeretin Alleviates Cisplatin-Induced Acute Hepatic Injury in Rats: Targeting MAPKs and Apoptosis.

artículo científico publicado en 2016

Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma

artículo científico publicado en 2009

The impact of Catechol-O-methyl transferase knockdown on the cell proliferation of hormone-responsive cancers

artículo científico publicado en 2019

Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer and anti-inflammatory activities

artículo científico publicado en 2019

Lista de obras de Hany A. Omar

3-methyl-2-phenyl-1-substituted-indole derivatives as indomethacin analogs: design, synthesis and biological evaluation as potential anti-inflammatory and analgesic agents.

6-Shogaol induces cell cycle arrest and apoptosis in human hepatoma cells through pleiotropic mechanisms

A neuroprotective role of kaempferol against chlorpyrifos-induced oxidative stress and memory deficits in rats via GSK3β-Nrf2 signaling pathway

A novel indole-3-carbinol derivative inhibits the growth of human oral squamous cell carcinoma in vitro.

Antiproliferative activity of cycloalkanecarboxamide derivatives possessing sulfonate or sulfamate moiety

Antitumor effects of (S)-HDAC42, a phenylbutyrate-derived histone deacetylase inhibitor, in multiple myeloma cells.

Antitumor effects of OSU-2S, a nonimmunosuppressive analogue of FTY720, in hepatocellular carcinoma ⬇️

Antitumor effects of energy restriction-mimetic agents: thiazolidinediones.

Antrodia cinnamomea boosts the anti-tumor activity of sorafenib in xenograft models of human hepatocellular carcinoma

BACE1 inhibitors: Current status and future directions in treating Alzheimer's disease

Bee Pollen: Current Status and Therapeutic Potential

Caffeic Acid Phenethyl Ester: A Review of Its Antioxidant Activity, Protective Effects against Ischemia-reperfusion Injury and Drug Adverse Reactions

Caffeic acid phenethyl ester guards against benign prostate hypertrophy in rats: Role of IGF-1R/protein kinase-B (Akt)/β-catenin signaling.

Caffeic acid phenethyl ester protects against glucocorticoid-induced osteoporosis in vivo: Impact on oxidative stress and RANKL/OPG signals.

Camel Milk Attenuates Rheumatoid Arthritis Via Inhibition of Mitogen Activated Protein Kinase Pathway.

Camel's milk ameliorates TNBS-induced colitis in rats via downregulation of inflammatory cytokines and oxidative stress

Design and synthesis of new energy restriction mimetic agents: Potent anti-tumor activities of hybrid motifs of aminothiazoles and coumarins

Design, synthesis and analgesic/anti-inflammatory evaluation of novel diarylthiazole and diarylimidazole derivatives towards selective COX-1 inhibitors with better gastric profile.

Design, synthesis and anticancer evaluation of novel spirobenzo[h]chromene and spirochromane derivatives with dual EGFR and B-RAF inhibitory activities.

Design, synthesis and biological evaluation of new pyrrolidine carboxamide analogues as potential chemotherapeutic agents for hepatocellular carcinoma.

Design, synthesis and biological evaluation of novel diphenylthiazole-based cyclooxygenase inhibitors as potential anticancer agents.

Design, synthesis and biological evaluation of novel triaryl (Z)-olefins as tamoxifen analogues.

Design, synthesis and biological evaluation of some novel benzothiazole/benzoxazole and/or benzimidazole derivatives incorporating a pyrazole scaffold as antiproliferative agents

Design, synthesis and pharmacological evaluation of omeprazole-like agents with anti-inflammatory activity

Design, synthesis, biological evaluation, and modeling studies of novel conformationally-restricted analogues of sorafenib as selective kinase-inhibitory antiproliferative agents against hepatocellular carcinoma cells

Diosmin protects against ethanol-induced gastric injury in rats: novel anti-ulcer actions

Energy restriction as an antitumor target

Energy restriction: stepping stones towards cancer therapy

Enhancing the Anticancer Activity of Antrodia cinnamomea in Hepatocellular Carcinoma Cells via Cocultivation With Ginger: The Impact on Cancer Cell Survival Pathways

Gliclazide attenuates acetic acid-induced colitis via the modulation of PPARγ, NF-κB and MAPK signaling pathways

Glutamyl cysteine dipeptide suppresses ferritin expression and alleviates liver injury in iron-overload rat model.

Hesperidin alleviates cisplatin-induced hepatotoxicity in rats without inhibiting its antitumor activity.

Identification of SEPTIN12 as a novel target of the androgen and estrogen receptors in human testicular cells

Immunomodulatory MicroRNAs in cancer: targeting immune checkpoints and the tumor microenvironment

Immunotherapy, an evolving approach for the management of triple negative breast cancer: Converting non-responders to responders.

Iron supplementation at high altitudes induces inflammation and oxidative injury to lung tissues in rats.

L-carnitine mitigates UVA-induced skin tissue injury in rats through downregulation of oxidative stress, p38/c-Fos signaling, and the proinflammatory cytokines.

Mechanical and phytochemical protection mechanisms of Calligonum comosum in arid deserts.

Modulation of cyclins, p53 and mitogen-activated protein kinases signaling in breast cancer cell lines by 4-(3,4,5-trimethoxyphenoxy)benzoic acid

Multidirectional desymmetrization of pluripotent building block en route to diastereoselective synthesis of complex nature-inspired scaffolds

Nicotine mediates hypochlorous acid-induced nuclear protein damage in mammalian cells

Novel diphenylthiazole derivatives with multi-target mechanism: Synthesis, docking study, anticancer and anti-inflammatory activities.

Novel pyrazolopyrimidine derivatives targeting COXs and iNOS enzymes; design, synthesis and biological evaluation as potential anti-inflammatory agents.

Nuclear factor erythroid-2-related factor regulates LRWD1 expression and cellular adaptation to oxidative stress in human embryonal carcinoma cells

OSU-2S/Sorafenib Synergistic Antitumor Combination against Hepatocellular Carcinoma: The Role of PKCδ/p53.

OSU-A9 inhibits angiogenesis in human umbilical vein endothelial cells via disrupting Akt-NF-κB and MAPK signaling pathways.

OSU-A9, a potent indole-3-carbinol derivative, suppresses breast tumor growth by targeting the Akt-NF-kappaB pathway and stress response signaling

OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro

Potential targets of energy restriction mimetic agents in cancer cells

Pyrrolizines: Design, synthesis, anticancer evaluation and investigation of the potential mechanism of action

Reactive oxygen species mediate Terbufos-induced apoptosis in mouse testicular cell lines via the modulation of cell cycle and pro-apoptotic proteins

Recent advances with alkaline phosphatase isoenzymes and their inhibitors

Sensitization of hepatocellular carcinoma cells to Apo2L/TRAIL by a novel Akt/NF-κB signalling inhibitor

Sequencing [4 + 1]-Cycloaddition and Aza-Michael Addition Reactions: A Diastereoselective Cascade for the Rapid Access of Pyrido[2',1':2,3]/Thiazolo[2',3':2,3]imidazo[1,5-a]quinolone Scaffolds as Potential Antibacterial and Anticancer Motifs

Synthesis, biological evaluation, and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase

Synthesis, characterization and biological evaluation of novel 4'-fluoro-2'-hydroxy-chalcone derivatives as antioxidant, anti-inflammatory and analgesic agents

Tackling Cancer Resistance by Immunotherapy: Updated Clinical Impact and Safety of PD-1/PD-L1 Inhibitors

Tackling molecular targets beyond PD-1/PD-L1: Novel approaches to boost patients' response to cancer immunotherapy

Tackling the cytokine storm in COVID-19, challenges and hopes

Tangeretin Alleviates Cisplatin-Induced Acute Hepatic Injury in Rats: Targeting MAPKs and Apoptosis.

Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma

The impact of Catechol-O-methyl transferase knockdown on the cell proliferation of hormone-responsive cancers

Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer and anti-inflammatory activities