Lista de obras - Jochen Walter - Dominio Público Uruguay

&#947;-Secretase, Apolipoprotein E and Cellular Cholesterol Metabolism ⬇️

artículo científico publicado el 1 de febrero de 2012

A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2

scientific article published on 15 September 2019

A reporter cell system for the triggering receptor expressed on myeloid cells 2 reveals differential effects of disease-associated variants on receptor signaling and activation by antibodies against the stalk region

scientific article published on 14 December 2020

APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation.

artículo científico publicado en 2013

Altered Sphingolipid Balance in Capillary Cerebral Amyloid Angiopathy.

artículo científico publicado en 2016

Alzheimer's Disease Associated Presenilin-1 Holoprotein and Its 18−20 kDa C-Terminal Fragment Are Death Substrates for Proteases of the Caspase Family ⬇️

artículo científico publicado el 24 de febrero de 1998

Apical Sorting of β-Secretase Limits Amyloid β-Peptide Production ⬇️

artículo científico publicado el 6 de diciembre de 2001

BRI2 Protein Regulates β-Amyloid Degradation by Increasing Levels of Secreted Insulin-degrading Enzyme (IDE) ⬇️

artículo científico publicado el 26 de agosto de 2011

Deficiency of sphingosine-1-phosphate lyase impairs lysosomal metabolism of the amyloid precursor protein

artículo científico publicado en 2014

Deposition of phosphorylated amyloid-β in brains of aged nonhuman primates and canines.

artículo científico publicado en 2018

Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer's disease mouse model

scientific article published on 20 March 2019

Different aspects of Alzheimer's disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia

artículo científico publicado en 2019

Erratum

scholarly article published in Autophagy

Fishing for function – distinct roles of Bace1 and Bace2 in Zebrafish development ⬇️

artículo científico publicado el 25 de marzo de 2013

Functional Relevance of a Novel SlyX Motif in Non-conventional Secretion of Insulin-degrading Enzyme ⬇️

artículo científico publicado el 16 de mayo de 2011

Functional involvement of γ-secretase in signaling of the triggering receptor expressed on myeloid cells-2 (TREM2).

artículo científico publicado en 2016

GGA1 overexpression attenuates amyloidogenic processing of the amyloid precursor protein in Niemann-Pick type C cells.

artículo científico publicado en 2014

Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid-β Precursor Protein ⬇️

artículo científico publicado el 27 de agosto de 2012

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Impact of amyloid β aggregate maturation on antibody treatment in APP23 mice

artículo científico publicado en 2015

Importance of γ-secretase in the regulation of liver X receptor and cellular lipid metabolism

scientific article published on 30 April 2020

Interplay between phosphorylation and palmitoylation mediates plasma membrane targeting and sorting of GAP43.

artículo científico publicado en 2014

Intramembranous processing by γ-secretase regulates reverse signaling of ephrin-B2 in migration of microglia

artículo científico publicado en 2017

Investigation of Aβ phosphorylated at serine 8 (pAβ) in Alzheimer's disease, dementia with Lewy bodies and vascular dementia

artículo científico publicado en 2015

Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease

artículo científico publicado en 2015

Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis

artículo científico publicado en 2008

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease

artículo científico publicado en 2017

Modified amyloid variants in pathological subgroups of β-amyloidosis

scientific article published on 06 June 2018

Phosphorylated Aβ peptides in human Down syndrome brain and different Alzheimer's-like mouse models

scientific article published on 29 July 2020

Phosphorylation Interferes with Maturation of Amyloid-β Fibrillar Structure in the N Terminus.

artículo científico publicado en 2016

Phosphorylation modifies the molecular stability of β-amyloid deposits.

artículo científico publicado en 2016

Phosphorylation of Amyloid-β Peptide at Serine 8 Attenuates Its Clearance via Insulin-degrading and Angiotensin-converting Enzymes ⬇️

artículo científico publicado el 20 de enero de 2012

Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity.

artículo científico publicado en 2016

Pleiotropic Effect of Human ApoE4 on Cerebral Ceramide and Saturated Fatty Acid Levels.

artículo científico publicado en 2016

Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.

artículo científico publicado en 2012

Presenilins and γ-Secretase in Membrane Proteostasis

artículo científico publicado en 2019

Proteolytic Fragments of the Alzheimer's Disease Associated Presenilins-1 and -2 Are Phosphorylated in Vivo by Distinct Cellular Mechanisms ⬇️

artículo científico publicado el 28 de abril de 1998

Sequential proteolytic processing of the triggering receptor expressed on myeloid cells-2 (TREM2) protein by ectodomain shedding and γ-secretase-dependent intramembranous cleavage

artículo científico publicado en 2013

Serotonin stimulates secretion of exosomes from microglia cells

artículo científico publicado en 2014

Sphingolipids: Critical players in Alzheimer’s disease ⬇️

artículo científico publicado el 23 de julio de 2012

Sphingosine 1-phosphate lyase ablation disrupts presynaptic architecture and function via an ubiquitin- proteasome mediated mechanism.

artículo científico publicado en 2016

Sphingosine-1-phosphate: boon and bane for the brain.

artículo científico publicado en 2014

Statins Promote the Degradation of Extracellular Amyloid β-Peptide by Microglia via Stimulation of Exosome-associated Insulin-degrading Enzyme (IDE) Secretion ⬇️

artículo científico publicado el 28 de septiembre de 2010

Synthesis, Radiosynthesis, and Preliminary in vitro and in vivo Evaluation of the Fluorinated Ceramide Trafficking Inhibitor (HPA-12) for Brain Applications

artículo científico publicado en 2017

TREM2 triggers microglial density and age-related neuronal loss

artículo científico publicado en 2018

The Triggering Receptor Expressed on Myeloid Cells 2: A Molecular Link of Neuroinflammation and Neurodegenerative Diseases

artículo científico

The intact Kunitz domain protects the amyloid precursor protein from being processed by matriptase-2.

artículo científico publicado en 2016

Trehalose Alters Subcellular Trafficking and the Metabolism of the Alzheimer-associated Amyloid Precursor Protein

artículo científico publicado en 2016

γ-Secretase in microglia - implications for neurodegeneration and neuroinflammation.

artículo científico publicado en 2017

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Jochen Walter

&amp;#947;-Secretase, Apolipoprotein E and Cellular Cholesterol Metabolism ⬇️

A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2

A reporter cell system for the triggering receptor expressed on myeloid cells 2 reveals differential effects of disease-associated variants on receptor signaling and activation by antibodies against the stalk region

APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation.

Altered Sphingolipid Balance in Capillary Cerebral Amyloid Angiopathy.

Alzheimer's Disease Associated Presenilin-1 Holoprotein and Its 18−20 kDa C-Terminal Fragment Are Death Substrates for Proteases of the Caspase Family ⬇️

Apical Sorting of β-Secretase Limits Amyloid β-Peptide Production ⬇️

BRI2 Protein Regulates β-Amyloid Degradation by Increasing Levels of Secreted Insulin-degrading Enzyme (IDE) ⬇️

Deficiency of sphingosine-1-phosphate lyase impairs lysosomal metabolism of the amyloid precursor protein

Deposition of phosphorylated amyloid-β in brains of aged nonhuman primates and canines.

Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer's disease mouse model

Different aspects of Alzheimer's disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia

Erratum

Fishing for function – distinct roles of Bace1 and Bace2 in Zebrafish development ⬇️

Functional Relevance of a Novel SlyX Motif in Non-conventional Secretion of Insulin-degrading Enzyme ⬇️

Functional involvement of γ-secretase in signaling of the triggering receptor expressed on myeloid cells-2 (TREM2).

GGA1 overexpression attenuates amyloidogenic processing of the amyloid precursor protein in Niemann-Pick type C cells.

Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid-β Precursor Protein ⬇️

Guidelines for the use and interpretation of assays for monitoring autophagy

Impact of amyloid β aggregate maturation on antibody treatment in APP23 mice

Importance of γ-secretase in the regulation of liver X receptor and cellular lipid metabolism

Interplay between phosphorylation and palmitoylation mediates plasma membrane targeting and sorting of GAP43.

Intramembranous processing by γ-secretase regulates reverse signaling of ephrin-B2 in migration of microglia

Investigation of Aβ phosphorylated at serine 8 (pAβ) in Alzheimer's disease, dementia with Lewy bodies and vascular dementia

Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease

Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease

Modified amyloid variants in pathological subgroups of β-amyloidosis

Phosphorylated Aβ peptides in human Down syndrome brain and different Alzheimer's-like mouse models

Phosphorylation Interferes with Maturation of Amyloid-β Fibrillar Structure in the N Terminus.

Phosphorylation modifies the molecular stability of β-amyloid deposits.

Phosphorylation of Amyloid-β Peptide at Serine 8 Attenuates Its Clearance via Insulin-degrading and Angiotensin-converting Enzymes ⬇️

Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity.

Pleiotropic Effect of Human ApoE4 on Cerebral Ceramide and Saturated Fatty Acid Levels.

Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.

Presenilins and γ-Secretase in Membrane Proteostasis

Proteolytic Fragments of the Alzheimer's Disease Associated Presenilins-1 and -2 Are Phosphorylated in Vivo by Distinct Cellular Mechanisms ⬇️

Sequential proteolytic processing of the triggering receptor expressed on myeloid cells-2 (TREM2) protein by ectodomain shedding and γ-secretase-dependent intramembranous cleavage

Serotonin stimulates secretion of exosomes from microglia cells

Sphingolipids: Critical players in Alzheimer’s disease ⬇️

Sphingosine 1-phosphate lyase ablation disrupts presynaptic architecture and function via an ubiquitin- proteasome mediated mechanism.

Sphingosine-1-phosphate: boon and bane for the brain.

Statins Promote the Degradation of Extracellular Amyloid β-Peptide by Microglia via Stimulation of Exosome-associated Insulin-degrading Enzyme (IDE) Secretion ⬇️

Synthesis, Radiosynthesis, and Preliminary in vitro and in vivo Evaluation of the Fluorinated Ceramide Trafficking Inhibitor (HPA-12) for Brain Applications

TREM2 triggers microglial density and age-related neuronal loss

The Triggering Receptor Expressed on Myeloid Cells 2: A Molecular Link of Neuroinflammation and Neurodegenerative Diseases

The intact Kunitz domain protects the amyloid precursor protein from being processed by matriptase-2.

Trehalose Alters Subcellular Trafficking and the Metabolism of the Alzheimer-associated Amyloid Precursor Protein

γ-Secretase in microglia - implications for neurodegeneration and neuroinflammation.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

γ-Secretase, Apolipoprotein E and Cellular Cholesterol Metabolism ⬇️