Lista de obras - Nathan K. LeBrasseur - Dominio Público Uruguay

17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization

artículo científico publicado en 2016

A longitudinal study of whole body, tissue, and cellular physiology in a mouse model of fibrosing NASH with high fidelity to the human condition.

artículo científico publicado en 2017

A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues

artículo científico publicado en 2022

Acute exercise activates AMPK and eNOS in the mouse aorta

artículo científico publicado en 2011

Adverse events associated with testosterone administration

artículo científico publicado en 2010

Body composition during childhood and adolescence: relations to bone strength and microstructure

artículo científico publicado en 2014

Brd2 disruption in mice causes severe obesity without Type 2 diabetes

artículo científico publicado en 2009

Building muscle, browning fat and preventing obesity by inhibiting myostatin.

artículo científico publicado en 2011

CXCL10-Mediates Macrophage, but not Other Innate Immune Cells-Associated Inflammation in Murine Nonalcoholic Steatohepatitis

artículo científico publicado en 2016

Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling

artículo científico publicado en 2004

Cellular Senescence and the Biology of Aging, Disease, and Frailty

artículo científico publicado en 2015

Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity.

artículo científico publicado en 2015

Cellular senescence mediates fibrotic pulmonary disease

artículo científico publicado en 2017

Cellular senescence: Implications for metabolic disease

artículo científico publicado en 2016

Changes in function and disability after resistance training: does velocity matter?: a pilot study

artículo científico publicado en 2003

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

artículo científico publicado en 2011

Clinical meaningfulness of the changes in muscle performance and physical function associated with testosterone administration in older men with mobility limitation

artículo científico publicado en 2011

Conditional deletion of Hdac3 in osteoprogenitor cells attenuates diet-induced systemic metabolic dysfunction.

artículo científico publicado en 2015

Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance

artículo científico publicado en 2008

Determinants of gait speed in COPD.

artículo científico publicado en 2014

Effects of Fenofibrate on Cardiac Remodeling in Aldosterone-Induced Hypertension

artículo científico publicado en 2007

Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes

artículo científico publicado en 2008

Energetic interventions for healthspan and resiliency with aging

artículo científico publicado en 2016

Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.

artículo científico publicado en 2016

Glycolytic fast-twitch muscle fiber restoration counters adverse age-related changes in body composition and metabolism.

artículo científico publicado en 2013

Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice.

artículo científico publicado en 2014

Habitual Physical Activity Levels Are Associated with Performance in Measures of Physical Function and Mobility in Older Men ⬇️

artículo científico publicado el 24 de agosto de 2010

High fat diet and exercise lead to a disrupted and pathogenic DNA methylome in mouse liver

artículo científico publicado en 2016

High-intensity resistance training improves muscle strength, self-reported function, and disability in long-term stroke survivors.

artículo científico publicado en 2004

High-velocity resistance training increases skeletal muscle peak power in older women

scientific article published on 01 April 2002

Identification of Senescent Cells in the Bone Microenvironment

artículo científico publicado en 2016

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.

artículo científico publicado en 2015

Liver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles

artículo científico publicado en 2014

Measuring gait speed in the out-patient clinic: methodology and feasibility.

artículo científico publicado en 2013

Muscle impairments and behavioral factors mediate functional limitations and disability following stroke.

artículo científico publicado en 2006

Myostatin and sarcopenia: opportunities and challenges - a mini-review.

artículo científico

Myostatin as a mediator of sarcopenia versus homeostatic regulator of muscle mass: insights using a new mass spectrometry-based assay

artículo científico publicado en 2015

Novel small molecule inhibition of IKK/NF-κB activation reduces markers of senescence and improves healthspan in mouse models of aging

artículo científico publicado en 2021

Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes

artículo científico publicado en 2005

Palmitate alters neuregulin signaling and biology in cardiac myocytes

scientific article published on 12 December 2008

Peroxisome proliferator-activated receptor alpha-independent actions of fenofibrate exacerbates left ventricular dilation and fibrosis in chronic pressure overload.

artículo científico publicado en 2007

Physical Resilience: Opportunities and Challenges in Translation

artículo científico publicado en 2017

Physiologic and metabolic safety of butyrylcholinesterase gene therapy in mice

artículo científico publicado en 2014

Postnatal PPARdelta activation and myostatin inhibition exert distinct yet complimentary effects on the metabolic profile of obese insulin-resistant mice

artículo científico publicado en 2010

Preclinical studies on neurobehavioral and neuromuscular effects of cocaine hydrolase gene therapy in mice.

artículo científico publicado en 2013

Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease.

artículo científico publicado en 2016

Regenerating skeletal muscle in the face of aging and disease

artículo científico publicado en 2014

Relationship between pre-transplant physical function and outcomes after kidney transplant

artículo científico publicado en 2017

Senolytics improve physical function and increase lifespan in old age

artículo científico publicado en 2018

Serum Neuregulin-1beta as a Biomarker of Cardiovascular Fitness.

artículo científico publicado en 2009

Shear wave elastography of passive skeletal muscle stiffness: influences of sex and age throughout adulthood

artículo científico publicado en 2014

Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals

artículo científico publicado en 2007

Skeletal muscle mass is associated with bone geometry and microstructure and serum insulin-like growth factor binding protein-2 levels in adult women and men.

artículo científico publicado en 2012

Substitution at carbon 2 of 19-nor-1α,25-dihydroxyvitamin D3 with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells ⬇️

artículo científico publicado el 3 de septiembre de 2011

TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess

artículo científico publicado en 2014

Targeting senescent cells enhances adipogenesis and metabolic function in old age

artículo científico publicado en 2015

The A2b adenosine receptor modulates glucose homeostasis and obesity

artículo científico publicado en 2012

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

artículo científico publicado en 2015

The Impact of Frailty on Patient-Centered Outcomes Following Aortic Valve Replacement

artículo científico publicado en 2017

The expression of neuregulin and erbB receptors in human skeletal muscle: effects of progressive resistance training.

artículo científico publicado en 2005

Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissues

artículo científico publicado en 2006

Time-restricted feeding prevents deleterious metabolic effects of circadian disruption through epigenetic control of β cell function

artículo científico publicado en 2021

Transcriptional profiling of testosterone-regulated genes in the skeletal muscle of human immunodeficiency virus-infected men experiencing weight loss

artículo científico publicado en 2007

Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice

artículo científico publicado en 2021

Why Might Thiazolidinediones Increase Exercise Capacity in Patients With Type 2 Diabetes?

artículo científico publicado en 2005

Lista de obras de Nathan K. LeBrasseur

17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization

A longitudinal study of whole body, tissue, and cellular physiology in a mouse model of fibrosing NASH with high fidelity to the human condition.

A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues

Acute exercise activates AMPK and eNOS in the mouse aorta

Adverse events associated with testosterone administration

Body composition during childhood and adolescence: relations to bone strength and microstructure

Brd2 disruption in mice causes severe obesity without Type 2 diabetes

Building muscle, browning fat and preventing obesity by inhibiting myostatin.

CXCL10-Mediates Macrophage, but not Other Innate Immune Cells-Associated Inflammation in Murine Nonalcoholic Steatohepatitis

Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling

Cellular Senescence and the Biology of Aging, Disease, and Frailty

Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity.

Cellular senescence mediates fibrotic pulmonary disease

Cellular senescence: Implications for metabolic disease

Changes in function and disability after resistance training: does velocity matter?: a pilot study

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

Clinical meaningfulness of the changes in muscle performance and physical function associated with testosterone administration in older men with mobility limitation

Conditional deletion of Hdac3 in osteoprogenitor cells attenuates diet-induced systemic metabolic dysfunction.

Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance

Determinants of gait speed in COPD.

Effects of Fenofibrate on Cardiac Remodeling in Aldosterone-Induced Hypertension

Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes

Energetic interventions for healthspan and resiliency with aging

Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.

Glycolytic fast-twitch muscle fiber restoration counters adverse age-related changes in body composition and metabolism.

Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice.

Habitual Physical Activity Levels Are Associated with Performance in Measures of Physical Function and Mobility in Older Men ⬇️

High fat diet and exercise lead to a disrupted and pathogenic DNA methylome in mouse liver

High-intensity resistance training improves muscle strength, self-reported function, and disability in long-term stroke survivors.

High-velocity resistance training increases skeletal muscle peak power in older women

Identification of Senescent Cells in the Bone Microenvironment

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.

Liver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles

Measuring gait speed in the out-patient clinic: methodology and feasibility.

Muscle impairments and behavioral factors mediate functional limitations and disability following stroke.

Myostatin and sarcopenia: opportunities and challenges - a mini-review.

Myostatin as a mediator of sarcopenia versus homeostatic regulator of muscle mass: insights using a new mass spectrometry-based assay

Novel small molecule inhibition of IKK/NF-κB activation reduces markers of senescence and improves healthspan in mouse models of aging

Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes

Palmitate alters neuregulin signaling and biology in cardiac myocytes

Peroxisome proliferator-activated receptor alpha-independent actions of fenofibrate exacerbates left ventricular dilation and fibrosis in chronic pressure overload.

Physical Resilience: Opportunities and Challenges in Translation

Physiologic and metabolic safety of butyrylcholinesterase gene therapy in mice

Postnatal PPARdelta activation and myostatin inhibition exert distinct yet complimentary effects on the metabolic profile of obese insulin-resistant mice

Preclinical studies on neurobehavioral and neuromuscular effects of cocaine hydrolase gene therapy in mice.

Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease.

Regenerating skeletal muscle in the face of aging and disease

Relationship between pre-transplant physical function and outcomes after kidney transplant

Senolytics improve physical function and increase lifespan in old age

Serum Neuregulin-1beta as a Biomarker of Cardiovascular Fitness.

Shear wave elastography of passive skeletal muscle stiffness: influences of sex and age throughout adulthood

Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals

Skeletal muscle mass is associated with bone geometry and microstructure and serum insulin-like growth factor binding protein-2 levels in adult women and men.

Substitution at carbon 2 of 19-nor-1α,25-dihydroxyvitamin D3 with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells ⬇️

TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess

Targeting senescent cells enhances adipogenesis and metabolic function in old age

The A2b adenosine receptor modulates glucose homeostasis and obesity

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

The Impact of Frailty on Patient-Centered Outcomes Following Aortic Valve Replacement

The expression of neuregulin and erbB receptors in human skeletal muscle: effects of progressive resistance training.

Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissues

Time-restricted feeding prevents deleterious metabolic effects of circadian disruption through epigenetic control of β cell function

Transcriptional profiling of testosterone-regulated genes in the skeletal muscle of human immunodeficiency virus-infected men experiencing weight loss

Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice

Why Might Thiazolidinediones Increase Exercise Capacity in Patients With Type 2 Diabetes?