Lista de obras - Nubia Boechat - Dominio Público Uruguay

2-(2-Acetylamino-5-chlorophenyl)-2,2-difluoroethanoic acid and 2-(2-acetylamino-5-methylphenyl)-2,2-difluoroethanoic acid, and 2-(2-acetylaminophenyl)-2,2-difluoro-N-phenylacetamide and 2-(2-acetylaminophenyl)-N-(4-chlorophenyl)-2,2-difluoroacetamid

artículo científico publicado en 2005

2-Amino-5-trifluoromethyl-1,3,4-thiadiazole and a redetermination of 2-amino-1,3,4-thiadiazole, both at 120 K: chains of edge-fused R(2)(2)(8) and R(4)(4)(10) rings, and sheets of R(2)(2)(8) and R(6)(6)(20) rings

artículo científico publicado en 2005

4-Difluoromethyl-1-(2,5-dimethoxyphenyl)-1H-1,2,3-triazole

4-Difluoromethyl-1-(4-methylphenyl)-1H-1,2,3-triazole

An update on the chemistry and medicinal chemistry of novel antimycobacterial compounds.

artículo científico

Anti-Plasmodium falciparum activity of quinoline-sulfonamide hybrids

artículo científico publicado en 2015

Chloroquine and Sulfadoxine Derivatives Inhibit ZIKV Replication in Cervical Cells

scientific article published on 29 December 2020

CoMFA/CoMSIA 3D-QSAR of pyrimidine inhibitors of Pneumocystis carinii dihydrofolate reductase

Corrigendum: The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication

artículo científico publicado en 2017

Current Antimalarial Therapies and Advances in the Development of Semi-Synthetic Artemisinin Derivatives

article published in 2018

Design, synthesis and activity against Trypanosoma cruzi of azaheterocyclic analogs of megazol.

artículo científico publicado en 2007

Design, synthesis and anti-P. falciparum activity of pyrazolopyridine-sulfonamide derivatives.

artículo científico publicado en 2016

Design, synthesis and pharmacological evaluation of HIV-1 reverse transcriptase inhibition of new indolin-2-ones.

artículo científico publicado en 2007

Editorial (Thematic Issue: New Developments in the Search for Agents to Treat Tuberculosis)

scientific article published on 01 January 2013

Enhanced activity of mefloquine and artesunic acid against Plasmodium falciparum in vitro and P. berghei in mice by combination with ciprofloxacin.

artículo científico publicado en 2006

Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors

artículo científico publicado en 2016

Evaluation of antimalarial and fluoroquinolone combinations against Plasmodium falciparum in vitro

artículo científico publicado en 2006

Evaluation of genotoxic effects of new molecules with possible trypanocidal activity for Chagas disease treatment

article

Fluorinated compounds against Mycobacterium tuberculosis.

artículo científico publicado en 2013

Fluorodenitrations using tetramethylammonium fluoride

Hydrogen-bonded chains in 5-methyl-2-trifluoromethyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one and hydrogen-bonded chains of rings in 5-amino-3-trifluoromethyl-1H-1,2,4-triazole-5-methyl-2-trifluoromethyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one (1/1

artículo científico publicado en 2004

Identification of Brazilian expertise in the fight against some neglected tropical diseases.

artículo científico publicado en 2012

Imatinib Mesylate: An Optimization in its Synthesis

article

Imatinib derivatives as inhibitors of K562 cells in chronic myeloid leukemia

article

In vitro genotoxicity of nitroimidazoles as a tool in the search of new trypanocidal agents

scientific article published on 27 June 2019

Megazol and its bioisostere 4H-1,2,4-triazole: comparing the trypanocidal, cytotoxic and genotoxic activities and their in vitro and in silico interactions with the Trypanosoma brucei nitroreductase enzyme

artículo científico publicado en 2014

N-(4-Chloro-phen-yl)ethanimidamide

artículo científico publicado en 2010

New 1,2,3-triazole-based analogues of benznidazole for use against Trypanosoma cruzi infection: in vitro and in vivo evaluations.

artículo científico publicado en 2018

New compounds hybrids 1h-1,2,3-triazole-quinoline against Plasmodium falciparum

artículo científico publicado en 2014

New efavirenz derivatives and 1,2,3-triazolyl-phosphonates as inhibitors of reverse transcriptase of HIV-1

article

New hybrid trifluoromethylquinolines as antiplasmodium agents

artículo científico publicado en 2019

New hydrazides derivatives of isoniazid against Mycobacterium tuberculosis: Higher potency and lower hepatocytotoxicity

artículo científico publicado en 2018

New pentasubstituted pyrrole hybrid atorvastatin-quinoline derivatives with antiplasmodial activity

artículo científico publicado en 2016

New pyrazolopyrimidine derivatives as Leishmania amazonensis arginase inhibitors

scientific article published on 17 May 2019

New trifluoromethyl triazolopyrimidines as anti-Plasmodium falciparum agents.

artículo científico publicado en 2012

Novel 1,2,3-triazole derivatives for use against Mycobacterium tuberculosis H37Rv (ATCC 27294) strain

artículo científico publicado en 2011

Novel Quinolinyl-pyrrolo[3,4-d]pyrimidine-2,5-dione Derivatives Against Chloroquine-resistant Plasmodium falciparum

artículo científico publicado en 2020

Novel nitroimidazole derivatives evaluated for their trypanocidal, cytotoxic, and genotoxic activities

artículo científico publicado en 2019

Novel polymorphs of the anti-Trypanosoma cruzi drug benznidazole

Novel selective inhibitor of Leishmania (Leishmania) amazonensis arginase

artículo científico publicado en 2015

On the Thermal Stability of the Diethylcarbamazine-Fortified Table Salt Used in the Control of Lymphatic Filariasis

article by Sara B Honorato et al published August 2016 in Journal of Pharmaceutical Sciences

One-Pot Synthesis of 1,3-Thiazolidin-4-Ones Derivatives from 2-Amino-1,3,4-Thiadiazole

Phenylamino-pyrimidine (PAP) Privileged Structure: Synthesis and Medicinal Applications

scientific article published on 01 January 2020

Phenylhydrazides as inhibitors of Leishmania amazonensis arginase and antileishmanial activity

scientific article published on 11 July 2019

Plasmodium falciparum dihydroorotate dehydrogenase: a drug target against malaria

scientific article published on 18 July 2018

Probing intermolecular interactions in a diethylcarbamazine citrate salt by fast MAS (1)H solid-state NMR spectroscopy and GIPAW calculations

artículo científico publicado en 2017

Recently reported biological activities of pyrazole compounds

artículo científico publicado en 2017

Repurposing strategies for Chagas disease therapy: the effect of imatinib and derivatives against Trypanosoma cruzi

artículo científico publicado en 2019

Safety assessment of MEFAS: an innovative hybrid salt of mefloquine and artesunate for malaria treatment

scientific article published on 07 May 2019

Studies of genotoxicity and mutagenicity of nitroimidazoles: demystifying this critical relationship with the nitro group.

artículo científico publicado en 2015

Synthesis and Trypanocidal Evaluation of News 5-[N-(3-(5-Substituted)- 1,3,4-Thiadiazolyl)]Amino-1-Methyl-4-Nitroimidazoles

Synthesis and anti-Plasmodium falciparum evaluation of novel pyrazolopyrimidine derivatives

Synthesis and antispasmodic activity of lidocaine derivatives endowed with reduced local anesthetic action

artículo científico publicado en 2007

Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents

artículo científico publicado en 2007

Synthesis, Biological Evaluation, and Molecular Modeling Studies of New Thiadiazole Derivatives as Potent P2X7 Receptor Inhibitors

artículo científico publicado en 2019

Sínteses e propriedades de fármacos inibidores da tirosina quinase BCR-ABL, utilizados no tratamento da Leucemia Mieloide Crônica

The Development of Novel Compounds Against Malaria: Quinolines, Triazolpyridines, Pyrazolopyridines and Pyrazolopyrimidines

scientific article published on 13 November 2019

The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication

artículo científico publicado en 2017

Three ethyl 5-amino-1-aryl-1H-imidazole-4-carboxylates: hydrogen-bonded supramolecular structures in one, two and three dimensions

Transmission-Blocking Potential of MEFAS, a Hybrid Compound Derived from Artesunate and Mefloquine

artículo científico publicado en 2016

Trifluoromethylation of Carbonyl Compounds

article

Vibrational spectra and quantum mechanical calculations of antiretroviral drugs: Nevirapine

article

Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo

artículo científico publicado en 2019

Lista de obras de Nubia Boechat

2-(2-Acetylamino-5-chlorophenyl)-2,2-difluoroethanoic acid and 2-(2-acetylamino-5-methylphenyl)-2,2-difluoroethanoic acid, and 2-(2-acetylaminophenyl)-2,2-difluoro-N-phenylacetamide and 2-(2-acetylaminophenyl)-N-(4-chlorophenyl)-2,2-difluoroacetamid

2-Amino-5-trifluoromethyl-1,3,4-thiadiazole and a redetermination of 2-amino-1,3,4-thiadiazole, both at 120 K: chains of edge-fused R(2)(2)(8) and R(4)(4)(10) rings, and sheets of R(2)(2)(8) and R(6)(6)(20) rings

4-Difluoromethyl-1-(2,5-dimethoxyphenyl)-1H-1,2,3-triazole

4-Difluoromethyl-1-(4-methylphenyl)-1H-1,2,3-triazole

An update on the chemistry and medicinal chemistry of novel antimycobacterial compounds.

Anti-Plasmodium falciparum activity of quinoline-sulfonamide hybrids

Chloroquine and Sulfadoxine Derivatives Inhibit ZIKV Replication in Cervical Cells

CoMFA/CoMSIA 3D-QSAR of pyrimidine inhibitors of Pneumocystis carinii dihydrofolate reductase

Corrigendum: The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication

Current Antimalarial Therapies and Advances in the Development of Semi-Synthetic Artemisinin Derivatives

Design, synthesis and activity against Trypanosoma cruzi of azaheterocyclic analogs of megazol.

Design, synthesis and anti-P. falciparum activity of pyrazolopyridine-sulfonamide derivatives.

Design, synthesis and pharmacological evaluation of HIV-1 reverse transcriptase inhibition of new indolin-2-ones.

Editorial (Thematic Issue: New Developments in the Search for Agents to Treat Tuberculosis)

Enhanced activity of mefloquine and artesunic acid against Plasmodium falciparum in vitro and P. berghei in mice by combination with ciprofloxacin.

Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors

Evaluation of antimalarial and fluoroquinolone combinations against Plasmodium falciparum in vitro

Evaluation of genotoxic effects of new molecules with possible trypanocidal activity for Chagas disease treatment

Fluorinated compounds against Mycobacterium tuberculosis.

Fluorodenitrations using tetramethylammonium fluoride

Hydrogen-bonded chains in 5-methyl-2-trifluoromethyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one and hydrogen-bonded chains of rings in 5-amino-3-trifluoromethyl-1H-1,2,4-triazole-5-methyl-2-trifluoromethyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one (1/1

Identification of Brazilian expertise in the fight against some neglected tropical diseases.

Imatinib Mesylate: An Optimization in its Synthesis

Imatinib derivatives as inhibitors of K562 cells in chronic myeloid leukemia

In vitro genotoxicity of nitroimidazoles as a tool in the search of new trypanocidal agents

Megazol and its bioisostere 4H-1,2,4-triazole: comparing the trypanocidal, cytotoxic and genotoxic activities and their in vitro and in silico interactions with the Trypanosoma brucei nitroreductase enzyme

N-(4-Chloro-phen-yl)ethanimidamide

New 1,2,3-triazole-based analogues of benznidazole for use against Trypanosoma cruzi infection: in vitro and in vivo evaluations.

New compounds hybrids 1h-1,2,3-triazole-quinoline against Plasmodium falciparum

New efavirenz derivatives and 1,2,3-triazolyl-phosphonates as inhibitors of reverse transcriptase of HIV-1

New hybrid trifluoromethylquinolines as antiplasmodium agents

New hydrazides derivatives of isoniazid against Mycobacterium tuberculosis: Higher potency and lower hepatocytotoxicity

New pentasubstituted pyrrole hybrid atorvastatin-quinoline derivatives with antiplasmodial activity

New pyrazolopyrimidine derivatives as Leishmania amazonensis arginase inhibitors

New trifluoromethyl triazolopyrimidines as anti-Plasmodium falciparum agents.

Novel 1,2,3-triazole derivatives for use against Mycobacterium tuberculosis H37Rv (ATCC 27294) strain

Novel Quinolinyl-pyrrolo[3,4-d]pyrimidine-2,5-dione Derivatives Against Chloroquine-resistant Plasmodium falciparum

Novel nitroimidazole derivatives evaluated for their trypanocidal, cytotoxic, and genotoxic activities

Novel polymorphs of the anti-Trypanosoma cruzi drug benznidazole

Novel selective inhibitor of Leishmania (Leishmania) amazonensis arginase

On the Thermal Stability of the Diethylcarbamazine-Fortified Table Salt Used in the Control of Lymphatic Filariasis

One-Pot Synthesis of 1,3-Thiazolidin-4-Ones Derivatives from 2-Amino-1,3,4-Thiadiazole

Phenylamino-pyrimidine (PAP) Privileged Structure: Synthesis and Medicinal Applications

Phenylhydrazides as inhibitors of Leishmania amazonensis arginase and antileishmanial activity

Plasmodium falciparum dihydroorotate dehydrogenase: a drug target against malaria

Probing intermolecular interactions in a diethylcarbamazine citrate salt by fast MAS (1)H solid-state NMR spectroscopy and GIPAW calculations

Recently reported biological activities of pyrazole compounds

Repurposing strategies for Chagas disease therapy: the effect of imatinib and derivatives against Trypanosoma cruzi

Safety assessment of MEFAS: an innovative hybrid salt of mefloquine and artesunate for malaria treatment

Studies of genotoxicity and mutagenicity of nitroimidazoles: demystifying this critical relationship with the nitro group.

Synthesis and Trypanocidal Evaluation of News 5-[N-(3-(5-Substituted)- 1,3,4-Thiadiazolyl)]Amino-1-Methyl-4-Nitroimidazoles

Synthesis and anti-Plasmodium falciparum evaluation of novel pyrazolopyrimidine derivatives

Synthesis and antispasmodic activity of lidocaine derivatives endowed with reduced local anesthetic action

Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents

Synthesis, Biological Evaluation, and Molecular Modeling Studies of New Thiadiazole Derivatives as Potent P2X7 Receptor Inhibitors

Sínteses e propriedades de fármacos inibidores da tirosina quinase BCR-ABL, utilizados no tratamento da Leucemia Mieloide Crônica

The Development of Novel Compounds Against Malaria: Quinolines, Triazolpyridines, Pyrazolopyridines and Pyrazolopyrimidines

The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication

Three ethyl 5-amino-1-aryl-1H-imidazole-4-carboxylates: hydrogen-bonded supramolecular structures in one, two and three dimensions

Transmission-Blocking Potential of MEFAS, a Hybrid Compound Derived from Artesunate and Mefloquine

Trifluoromethylation of Carbonyl Compounds

Vibrational spectra and quantum mechanical calculations of antiretroviral drugs: Nevirapine

Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo