Lista de obras - Robert J. Homer - Dominio Público Uruguay

A 34-year-old man presenting with gradual onset of shortness of breath and interstitial lung disease

artículo científico

A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk

artículo científico publicado en 2008

A critical regulatory role for macrophage migration inhibitory factor in hyperoxia-induced injury in the developing murine lung

artículo científico publicado en 2013

A critical role of SHP-1 in regulation of type 2 inflammation in the lung

artículo científico publicado en 2008

A role for matrix metalloproteinase 9 in IFNγ-mediated injury in developing lungs: relevance to bronchopulmonary dysplasia

artículo científico publicado en 2011

A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma

scholarly article

ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES AS MARKERS FOR SYSTEMIC AUTOIMMUNE DISEASE

article

Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation

artículo científico publicado en 2004

Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells

artículo científico publicado en 2008

Activation of the STAT pathway in acute lung injury

artículo científico publicado en 2004

Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis

artículo científico publicado en 2006

Airway epithelial MyD88 restores control of Pseudomonas aeruginosa murine infection via an IL-1-dependent pathway

artículo científico publicado en 2011

Airway hyper-reactivity mediated by B-1 cell immunoglobulin M antibody generating complement C5a at 1 day post-immunization in a murine hapten model of non-atopic asthma

artículo científico publicado en 2004

Airway remodeling and RELM-β

article

An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection

artículo científico publicado en 2014

Approach to the ground-glass nodule

artículo científico

Back to the future: historical perspective on the pathogenesis of idiopathic pulmonary fibrosis

artículo científico publicado en 2005

Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury

artículo científico publicado en 2005

Bcl-2–related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury

article

Benign pulmonary epithelial inclusions within the pleura: a case report

artículo científico publicado en 2007

CD4+CD25+FoxP3+ Regulatory Tregs inhibit fibrocyte recruitment and fibrosis via suppression of FGF-9 production in the TGF-β1 exposed murine lung

artículo científico publicado en 2014

Case study review

artículo científico publicado en 2005

Cathepsin E promotes pulmonary emphysema via mitochondrial fission

artículo científico publicado en 2014

Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis

artículo científico publicado en 2014

Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma

artículo científico publicado en 2005

Chronic inflammation and lung fibrosis: pleotropic syndromes but limited distinct phenotypes

artículo científico

Comparison of Transbronchial and Cryobiopsies in Evaluation of Diffuse Parenchymal Lung Disease

artículo científico publicado en 2016

Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung

artículo científico publicado en 2015

Cutting Edge: Limiting MHC Class II Expression to Dendritic Cells Alters the Ability to Develop Th2- Dependent Allergic Airway Inflammation

artículo científico publicado en 2009

Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro

artículo científico publicado en 2003

Cytokines

Developmental differences in the responses of IL-6 and IL-13 transgenic mice exposed to hyperoxia

artículo científico publicado en 2007

Developmental regulation of NO-mediated VEGF-induced effects in the lung

artículo científico publicado en 2008

Diagnosing idiopathic pulmonary fibrosis without a lung biopsy: honeycombing not required

artículo científico publicado en 2017

Differences in Pathology, Staging, and Treatment between HIV+ and Uninfected Patients with Microscopically Confirmed Hepatocellular Carcinoma

scientific article published on 01 October 2019

Differential expression of chitinases identify subsets of murine airway epithelial cells in allergic inflammation

artículo científico publicado en 2006

Drug sensitivity and allele-specificity of first-line osimertinib resistance EGFR mutations

scientific article published on 19 March 2020

Duodenal hemangioendothelioma: a case report ⬇️

artículo científico publicado el 1 de mayo de 1998

EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth

artículo científico publicado en 2024

ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo

artículo científico publicado en 2005

Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis

artículo científico publicado en 2004

Endobronchial Ultrasound-Guided Cautery-Assisted Transbronchial Forceps Biopsies: Safety and Sensitivity Relative to Transbronchial Needle Aspiration

artículo científico publicado en 2016

Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production

artículo científico publicado en 2008

Enhanced innate immune responsiveness to pulmonary Cryptococcus neoformans infection is associated with resistance to progressive infection.

artículo científico publicado en 2008

Eosinophilic pneumonia as a presentation of occult chronic granulomatous disease

artículo científico publicado en 1997

Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation.

artículo científico publicado en 2010

Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung

artículo científico publicado en 2006

Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation

artículo científico publicado en 1998

Genetic control of transforming growth factor-beta1-induced emphysema and fibrosis in the murine lung

artículo científico publicado en 2006

Genetic, serological and functional analysis of I-J molecules.

artículo científico publicado en 1985

Granulomatous bronchiolitis of Crohn's disease successfully treated with inhaled budesonide.

artículo científico publicado en 2009

High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology

artículo científico publicado en 2010

High expression of mammalian target of rapamycin is associated with better outcome for patients with early stage lung adenocarcinoma

artículo científico publicado en 2009

Hubert Humphrey's bladder cancer

artículo científico publicado en 1994

Hyperoxia and interferon-γ-induced injury in developing lungs occur via cyclooxygenase-2 and the endoplasmic reticulum stress-dependent pathway

artículo científico publicado en 2013

Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death

artículo científico publicado en 2006

IFN-gamma-dependent DNA injury and/or apoptosis are critical in cigarette smoke-induced murine emphysema

artículo científico publicado en 2006

IFN-γ acts on the airway epithelium to inhibit local and systemic pathology in allergic airway disease

artículo científico publicado en 2011

IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension

artículo científico publicado en 2012

IL-6 receptor α defines effector memory CD8+ T cells producing Th2 cytokines and expanding in asthma

artículo científico publicado en 2014

IL9 leads to airway inflammation by inducing IL13 expression in airway epithelial cells

artículo científico publicado en 2006

Identification and validation of differentially expressed transcripts by RNA-sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic Pulmonary Fibrosis

artículo científico publicado en 2017

Identification of EGFR mutation, KRAS mutation, and ALK gene rearrangement in cytological specimens of primary and metastatic lung adenocarcinoma.

artículo científico publicado en 2013

Idiopathic pulmonary fibrosis: new insights into pathogenesis

artículo científico publicado en 2004

Increased hyperoxia-induced lung injury in nitric oxide synthase 2 null mice is mediated via angiopoietin 2.

artículo científico publicado en 2012

Increased susceptibility of Cftr-/- mice to LPS-induced lung remodeling

artículo científico publicado en 2016

Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production

artículo científico publicado en 1997

Inhibition of Regulatory-Associated Protein of Mechanistic Target of Rapamycin Prevents Hyperoxia-Induced Lung Injury by Enhancing Autophagy and Reducing Apoptosis in Neonatal Mice.

artículo científico publicado en 2016

Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3

scientific journal article

Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4

artículo científico publicado en 2010

Inhibition of the Src and Jak kinases protects against lipopolysaccharide-induced acute lung injury

artículo científico publicado en 2005

Interferon gamma induction of pulmonary emphysema in the adult murine lung

artículo científico publicado en 2000

Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).

artículo científico publicado en 2001

Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T cells and interleukin-9.

artículo científico publicado en 2002

Interstitial lung disease in the connective tissue diseases

artículo científico

Massive cavitary pulmonary rheumatoid nodules in a patient with HIV.

artículo científico publicado en 2006

Matrix Metalloproteinase-Targeted Imaging of Lung Inflammation and Remodeling

artículo científico publicado en 2016

Molecular classification of nonsmall cell lung cancer using a 4-protein quantitative assay

article

Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease

artículo científico publicado en 2016

New insights into the pathogenesis of asthma

article

New insights into the pathogenesis of asthma

Of lungs, lipids, and lollipops

artículo científico publicado en 2009

Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells

artículo científico publicado en 2016

Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13–induced inflammation and remodeling

article

P21 regulates TGF-beta1-induced pulmonary responses via a TNF-alpha-signaling pathway

artículo científico publicado en 2007

Pathologists' staging of multiple foci of lung cancer: poor concordance in absence of dramatic histologic or molecular differences

artículo científico publicado en 2015

Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis

artículo científico publicado en 2016

Preparation, characterization, and evaluation of a monoclonal antibody against the rabbit platelet glycoprotein IIb/IIIa in an experimental angioplasty model

article

Primary malignant melanoma of the transverse colon: report of a case and review of the literature

artículo científico publicado en 2007

Pulmonary expression of leukemia inhibitory factor induces B cell hyperplasia and confers protection in hyperoxia

artículo científico publicado en 2003

Pulmonary manifestations of rheumatoid arthritis

artículo científico publicado en 2010

RIG-like helicase innate immunity inhibits vascular endothelial growth factor tissue responses via a type I IFN-dependent mechanism

artículo científico publicado en 2011

Recent advances in pulmonary fibrosis: implications for scleroderma

artículo científico publicado en 2010

Regression of murine lung tumors by the let-7 microRNA

artículo científico publicado en 2010

Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes

artículo científico publicado en 1997

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

artículo científico publicado en 2005

Regulation of pulmonary fibrosis by chemokine receptor CXCR3

artículo científico publicado en 2004

Regulation of pulmonary fibrosis by chemokine receptor CXCR3

article

Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema

artículo científico publicado en 2005

Role of Nitric Oxide Isoforms in Vascular and Alveolar Development and Lung Injury in Vascular Endothelial Growth Factor Overexpressing Neonatal Mice Lungs

artículo científico publicado en 2016

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis

scientific article published on 04 May 2009

Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema

artículo científico publicado en 2010

Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling

artículo científico publicado en 2006

Role of semaphorin 7a signaling in transforming growth factor β1-induced lung fibrosis and scleroderma-related interstitial lung disease

artículo científico publicado en 2011

Role of tissue protection in lethal respiratory viral-bacterial coinfection

artículo científico publicado en 2013

SH2 Domain-Containing Phosphatase-2 Is a Novel Antifibrotic Regulator in Pulmonary Fibrosis.

artículo científico publicado en 2016

Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis

artículo científico publicado en 2007

Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis

artículo científico publicado en 2012

Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis

artículo científico publicado en 2020

State of the art. Mechanistic heterogeneity in chronic obstructive pulmonary disease: insights from transgenic mice

artículo científico publicado en 2006

Susceptibility to progressive Cryptococcus neoformans pulmonary infection is regulated by loci on mouse chromosomes 1 and 9.

artículo científico publicado en 2012

T cell unresponsiveness correlates with quantitative TCR levels in a transgenic model

article

T helper 1 cells and interferon gamma regulate allergic airway inflammation and mucus production

artículo científico publicado en 1999

TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P.

artículo científico publicado en 2010

Targeted Lung Expression of Interleukin-11 Enhances Murine Tolerance of 100% Oxygen and Diminishes Hyperoxia-Induced DNA Fragmentation

artículo científico publicado en 1999

Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction

artículo científico publicado en 1996

Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling

artículo científico publicado en 2002

The Airway in Idiopathic Pulmonary Fibrosis: Protecting the Lung or Promoting Disease?

artículo científico publicado en 2016

Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis

artículo científico publicado en 2020

Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function.

artículo científico publicado en 2017

Thyroid transcription factor 1 is an independent prognostic factor for patients with stage I lung adenocarcinoma

artículo científico publicado en 2008

Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12.

artículo científico publicado en 2007

Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling

artículo científico publicado en 2006

Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways

artículo científico publicado en 2002

Use of the tetracycline-controlled transcriptional silencer (tTS) to eliminate transgene leak in inducible overexpression transgenic mice.

artículo científico publicado en 2001

Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung.

artículo científico publicado en 2004

Zika virus causes testicular atrophy

artículo científico publicado en 2017

Lista de obras de Robert J. Homer

A 34-year-old man presenting with gradual onset of shortness of breath and interstitial lung disease

A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk

A critical regulatory role for macrophage migration inhibitory factor in hyperoxia-induced injury in the developing murine lung

A critical role of SHP-1 in regulation of type 2 inflammation in the lung

A role for matrix metalloproteinase 9 in IFNγ-mediated injury in developing lungs: relevance to bronchopulmonary dysplasia

A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma

ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES AS MARKERS FOR SYSTEMIC AUTOIMMUNE DISEASE

Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation

Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells

Activation of the STAT pathway in acute lung injury

Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis

Airway epithelial MyD88 restores control of Pseudomonas aeruginosa murine infection via an IL-1-dependent pathway

Airway hyper-reactivity mediated by B-1 cell immunoglobulin M antibody generating complement C5a at 1 day post-immunization in a murine hapten model of non-atopic asthma

Airway remodeling and RELM-β

An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection

Approach to the ground-glass nodule

Back to the future: historical perspective on the pathogenesis of idiopathic pulmonary fibrosis

Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury

Bcl-2–related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury

Benign pulmonary epithelial inclusions within the pleura: a case report

CD4+CD25+FoxP3+ Regulatory Tregs inhibit fibrocyte recruitment and fibrosis via suppression of FGF-9 production in the TGF-β1 exposed murine lung

Case study review

Cathepsin E promotes pulmonary emphysema via mitochondrial fission

Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis

Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma

Chronic inflammation and lung fibrosis: pleotropic syndromes but limited distinct phenotypes

Comparison of Transbronchial and Cryobiopsies in Evaluation of Diffuse Parenchymal Lung Disease

Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung

Cutting Edge: Limiting MHC Class II Expression to Dendritic Cells Alters the Ability to Develop Th2- Dependent Allergic Airway Inflammation

Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro

Cytokines

Developmental differences in the responses of IL-6 and IL-13 transgenic mice exposed to hyperoxia

Developmental regulation of NO-mediated VEGF-induced effects in the lung

Diagnosing idiopathic pulmonary fibrosis without a lung biopsy: honeycombing not required

Differences in Pathology, Staging, and Treatment between HIV+ and Uninfected Patients with Microscopically Confirmed Hepatocellular Carcinoma

Differential expression of chitinases identify subsets of murine airway epithelial cells in allergic inflammation

Drug sensitivity and allele-specificity of first-line osimertinib resistance EGFR mutations

Duodenal hemangioendothelioma: a case report ⬇️

EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth

ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo

Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis

Endobronchial Ultrasound-Guided Cautery-Assisted Transbronchial Forceps Biopsies: Safety and Sensitivity Relative to Transbronchial Needle Aspiration

Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production

Enhanced innate immune responsiveness to pulmonary Cryptococcus neoformans infection is associated with resistance to progressive infection.

Eosinophilic pneumonia as a presentation of occult chronic granulomatous disease

Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation.

Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung

Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation

Genetic control of transforming growth factor-beta1-induced emphysema and fibrosis in the murine lung

Genetic, serological and functional analysis of I-J molecules.

Granulomatous bronchiolitis of Crohn's disease successfully treated with inhaled budesonide.

High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology

High expression of mammalian target of rapamycin is associated with better outcome for patients with early stage lung adenocarcinoma

Hubert Humphrey's bladder cancer

Hyperoxia and interferon-γ-induced injury in developing lungs occur via cyclooxygenase-2 and the endoplasmic reticulum stress-dependent pathway

Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death

IFN-gamma-dependent DNA injury and/or apoptosis are critical in cigarette smoke-induced murine emphysema

IFN-γ acts on the airway epithelium to inhibit local and systemic pathology in allergic airway disease

IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension

IL-6 receptor α defines effector memory CD8+ T cells producing Th2 cytokines and expanding in asthma

IL9 leads to airway inflammation by inducing IL13 expression in airway epithelial cells

Identification and validation of differentially expressed transcripts by RNA-sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic Pulmonary Fibrosis

Identification of EGFR mutation, KRAS mutation, and ALK gene rearrangement in cytological specimens of primary and metastatic lung adenocarcinoma.

Idiopathic pulmonary fibrosis: new insights into pathogenesis

Increased hyperoxia-induced lung injury in nitric oxide synthase 2 null mice is mediated via angiopoietin 2.

Increased susceptibility of Cftr-/- mice to LPS-induced lung remodeling

Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production

Inhibition of Regulatory-Associated Protein of Mechanistic Target of Rapamycin Prevents Hyperoxia-Induced Lung Injury by Enhancing Autophagy and Reducing Apoptosis in Neonatal Mice.

Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3

Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4

Inhibition of the Src and Jak kinases protects against lipopolysaccharide-induced acute lung injury

Interferon gamma induction of pulmonary emphysema in the adult murine lung

Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).

Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T cells and interleukin-9.

Interstitial lung disease in the connective tissue diseases

Massive cavitary pulmonary rheumatoid nodules in a patient with HIV.

Matrix Metalloproteinase-Targeted Imaging of Lung Inflammation and Remodeling

Molecular classification of nonsmall cell lung cancer using a 4-protein quantitative assay

Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease