Lista de obras - Ora Schueler-Furman - Dominio Público Uruguay

A benchmark testing ground for integrating homology modeling and protein docking

artículo científico publicado en 2016

A model of anthrax toxin lethal factor bound to protective antigen.

artículo científico publicado en 2005

Anchoring of bacterial effectors to host membranes through host-mediated lipidation by prenylation: a common paradigm.

artículo científico publicado en 2011

Application of asymmetric statistical potentials to antibody-protein docking

artículo científico publicado en 2012

Autophosphorylation Activates Dictyostelium Myosin II Heavy Chain Kinase A by Providing a Ligand for an Allosteric Binding Site in the -Kinase Domain

artículo científico publicado en 2011

Can self-inhibitory peptides be derived from the interfaces of globular protein-protein interactions?

artículo científico publicado en 2010

ClusPro PeptiDock: efficient global docking of peptide recognition motifs using FFT.

artículo científico publicado en 2017

ClusPro in rounds 38 to 45 of CAPRI: Toward combining template-based methods with free docking

scientific article published on 06 March 2020

Community-wide assessment of protein-interface modeling suggests improvements to design methodology

artículo científico publicado en 2011

Computational approaches to investigating allostery

artículo científico publicado en 2016

Conserved residue clustering and protein structure prediction.

artículo científico publicado en 2003

Crucial roles of single residues in binding affinity, specificity, and promiscuity in the cellulosomal cohesin-dockerin interface

artículo científico publicado en 2015

Detection of Peptide-Binding Sites on Protein Surfaces Using the Peptimap Server

artículo científico publicado en 2017

Detection of peptide-binding sites on protein surfaces: the first step toward the modeling and targeting of peptide-mediated interactions

artículo científico publicado en 2013

Discrimination of near-native structures in protein-protein docking by testing the stability of local minima

artículo científico publicado en 2008

Druggable protein-protein interactions--from hot spots to hot segments.

artículo científico publicado en 2013

Encounter complexes and dimensionality reduction in protein-protein association

artículo científico publicado en 2014

Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks

artículo científico publicado en 2021

Escherichia coli Quorum-Sensing EDF, A Peptide Generated by Novel Multiple Distinct Mechanisms and Regulated by trans-Translation

artículo científico publicado en 2016

Evolving dual targeting of a prokaryotic protein in yeast.

artículo científico publicado en 2013

Examination of possible structural constraints of MHC-binding peptides by assessment of their native structure within their source proteins.

artículo científico publicado en 2001

Extending RosettaDock with water, sugar, and pH for prediction of complex structures and affinities for CAPRI rounds 20-27

artículo científico publicado en 2013

FlexPepDock lessons from CAPRI peptide-protein rounds and suggested new criteria for assessment of model quality and utility

artículo científico publicado en 2016

Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals

artículo científico publicado en 2006

Fractured genes: a novel genomic arrangement involving new split inteins and a new homing endonuclease family

artículo científico publicado en 2009

FunHunt: model selection based on energy landscape characteristics.

artículo científico publicado en 2008

Funnel hunting in a rough terrain: learning and discriminating native energy funnels.

artículo científico publicado en 2008

Harnessing protein folding neural networks for peptide–protein docking

artículo científico

High-resolution global peptide-protein docking using fragments-based PIPER-FlexPepDock.

artículo científico publicado en 2017

Host FIH-Mediated Asparaginyl Hydroxylation of Translocated Legionella pneumophila Effectors

artículo científico publicado en 2017

Identification of a novel class of farnesylation targets by structure-based modeling of binding specificity

artículo científico publicado en 2011

Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3.

artículo científico publicado en 2005

Improved side-chain modeling for protein-protein docking

artículo científico publicado en 2005

In silico and in vitro elucidation of BH3 binding specificity toward Bcl-2

artículo científico publicado en 2012

Indirect ELISA-based approach for comparative measurement of high-affinity cohesin-dockerin interactions.

artículo científico publicado en 2012

Is GAS1 a co-receptor for the GDNF family of ligands?

artículo científico publicado en 2006

MYORG is associated with recessive primary familial brain calcification

scientific article published on 15 November 2018

Minimizing and learning energy functions for side-chain prediction.

artículo científico publicado en 2008

Mitochondrial complex IV deficiency, caused by mutated COX6B1, is associated with encephalomyopathy, hydrocephalus and cardiomyopathy

artículo científico publicado en 2014

Modeling Peptide-Protein Structure and Binding Using Monte Carlo Sampling Approaches: Rosetta FlexPepDock and FlexPepBind

artículo científico publicado en 2017

Modeling beta-sheet peptide-protein interactions: Rosetta FlexPepDock in CAPRI rounds 38-45

artículo científico publicado en 2019

Modeling peptide-protein interactions

artículo científico publicado en 2012

Molecular pathogenesis of human CD59 deficiency

artículo científico publicado en 2018

Myelin-associated glycoprotein gene mutation causes Pelizaeus-Merzbacher disease-like disorder

scientific journal article

Parkin Somatic Mutations Link Melanoma and Parkinson's Disease

artículo científico publicado en 2016

Pathogens use structural mimicry of native host ligands as a mechanism for host receptor engagement

artículo científico publicado en 2013

Peptide docking and structure-based characterization of peptide binding: from knowledge to know-how.

artículo científico

Peptiderive server: derive peptide inhibitors from protein-protein interactions

artículo científico publicado en 2016

Phosphorylation of the WWOX Protein Regulates Its Interaction with p73

scientific article published on 17 March 2020

Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells

artículo científico publicado en 2015

Progress in modeling of protein structures and interactions

artículo científico publicado en 2005

Progress in protein-protein docking: atomic resolution predictions in the CAPRI experiment using RosettaDock with an improved treatment of side-chain flexibility

artículo científico publicado en 2005

Protein-peptide docking: opportunities and challenges.

artículo científico publicado en 2018

Protein-protein docking predictions for the CAPRI experiment

artículo científico publicado en 2003

Protein-protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations

artículo científico publicado en 2003

Rapid sampling of molecular motions with prior information constraints

artículo científico publicado en 2009

Rationally Designed Macrocyclic Peptides as Synergistic Agonists of LPS-Induced Inflammatory Response

artículo científico publicado en 2014

Relacin, a novel antibacterial agent targeting the Stringent Response

artículo científico publicado en 2012

Rosetta FlexPepDock ab-initio: simultaneous folding, docking and refinement of peptides onto their receptors

artículo científico publicado en 2011

Rosetta FlexPepDock web server--high resolution modeling of peptide-protein interactions

artículo científico publicado en 2011

Rosetta predictions in CASP5: successes, failures, and prospects for complete automation.

artículo científico publicado en 2003

RosettaDock in CAPRI rounds 6-12

artículo científico publicado en 2007

Structural basis for UFM1 transfer from UBA5 to UFC1

artículo científico publicado en 2021

Structure-Based Identification of HDAC8 Non-histone Substrates

artículo científico publicado en 2016

Structure-based prediction of HDAC6 substrates validated by enzymatic assay reveals determinants of promiscuity and detects new potential substrates

Sub-angstrom modeling of complexes between flexible peptides and globular proteins.

artículo científico publicado en 2010

The Escherichia coli extracellular death factor EDF induces the endoribonucleolytic activities of the toxins MazF and ChpBK.

artículo científico publicado en 2011

The SV40 capsid is stabilized by a conserved pentapeptide hinge of the major capsid protein VP1.

artículo científico publicado en 2008

The structural basis of peptide-protein binding strategies.

artículo científico publicado en 2010

The structure, dynamics, and energetics of protein adsorption-lessons learned from adsorption of statherin to hydroxyapatite

scientific article published on December 2007

Trans protein splicing of cyanobacterial split inteins in endogenous and exogenous combinations.

artículo científico publicado en 2007

Ubiquitination and degradation of the inhibitors of NF-kappaB

artículo científico publicado en 2010

Versatile communication strategies among tandem WW domain repeats

artículo científico publicado en 2015

Yeast aconitase mitochondrial import is modulated by interactions of its C and N terminal domains and Ssa1/2 (Hsp70).

artículo científico publicado en 2018

c-Abl phosphorylates E6AP and regulates its E3 ubiquitin ligase activity

artículo científico publicado en 2013

Lista de obras de Ora Schueler-Furman

A benchmark testing ground for integrating homology modeling and protein docking

A model of anthrax toxin lethal factor bound to protective antigen.

Anchoring of bacterial effectors to host membranes through host-mediated lipidation by prenylation: a common paradigm.

Application of asymmetric statistical potentials to antibody-protein docking

Autophosphorylation Activates Dictyostelium Myosin II Heavy Chain Kinase A by Providing a Ligand for an Allosteric Binding Site in the -Kinase Domain

Can self-inhibitory peptides be derived from the interfaces of globular protein-protein interactions?

ClusPro PeptiDock: efficient global docking of peptide recognition motifs using FFT.

ClusPro in rounds 38 to 45 of CAPRI: Toward combining template-based methods with free docking

Community-wide assessment of protein-interface modeling suggests improvements to design methodology

Computational approaches to investigating allostery

Conserved residue clustering and protein structure prediction.

Crucial roles of single residues in binding affinity, specificity, and promiscuity in the cellulosomal cohesin-dockerin interface

Detection of Peptide-Binding Sites on Protein Surfaces Using the Peptimap Server

Detection of peptide-binding sites on protein surfaces: the first step toward the modeling and targeting of peptide-mediated interactions

Discrimination of near-native structures in protein-protein docking by testing the stability of local minima

Druggable protein-protein interactions--from hot spots to hot segments.

Encounter complexes and dimensionality reduction in protein-protein association

Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks

Escherichia coli Quorum-Sensing EDF, A Peptide Generated by Novel Multiple Distinct Mechanisms and Regulated by trans-Translation

Evolving dual targeting of a prokaryotic protein in yeast.

Examination of possible structural constraints of MHC-binding peptides by assessment of their native structure within their source proteins.

Extending RosettaDock with water, sugar, and pH for prediction of complex structures and affinities for CAPRI rounds 20-27

FlexPepDock lessons from CAPRI peptide-protein rounds and suggested new criteria for assessment of model quality and utility

Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals

Fractured genes: a novel genomic arrangement involving new split inteins and a new homing endonuclease family

FunHunt: model selection based on energy landscape characteristics.

Funnel hunting in a rough terrain: learning and discriminating native energy funnels.

Harnessing protein folding neural networks for peptide–protein docking

High-resolution global peptide-protein docking using fragments-based PIPER-FlexPepDock.

Host FIH-Mediated Asparaginyl Hydroxylation of Translocated Legionella pneumophila Effectors

Identification of a novel class of farnesylation targets by structure-based modeling of binding specificity

Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3.

Improved side-chain modeling for protein-protein docking

In silico and in vitro elucidation of BH3 binding specificity toward Bcl-2

Indirect ELISA-based approach for comparative measurement of high-affinity cohesin-dockerin interactions.

Is GAS1 a co-receptor for the GDNF family of ligands?

MYORG is associated with recessive primary familial brain calcification

Minimizing and learning energy functions for side-chain prediction.

Mitochondrial complex IV deficiency, caused by mutated COX6B1, is associated with encephalomyopathy, hydrocephalus and cardiomyopathy

Modeling Peptide-Protein Structure and Binding Using Monte Carlo Sampling Approaches: Rosetta FlexPepDock and FlexPepBind

Modeling beta-sheet peptide-protein interactions: Rosetta FlexPepDock in CAPRI rounds 38-45

Modeling peptide-protein interactions

Molecular pathogenesis of human CD59 deficiency

Myelin-associated glycoprotein gene mutation causes Pelizaeus-Merzbacher disease-like disorder

Parkin Somatic Mutations Link Melanoma and Parkinson's Disease

Pathogens use structural mimicry of native host ligands as a mechanism for host receptor engagement

Peptide docking and structure-based characterization of peptide binding: from knowledge to know-how.

Peptiderive server: derive peptide inhibitors from protein-protein interactions

Phosphorylation of the WWOX Protein Regulates Its Interaction with p73

Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells

Progress in modeling of protein structures and interactions

Progress in protein-protein docking: atomic resolution predictions in the CAPRI experiment using RosettaDock with an improved treatment of side-chain flexibility

Protein-peptide docking: opportunities and challenges.

Protein-protein docking predictions for the CAPRI experiment

Protein-protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations

Rapid sampling of molecular motions with prior information constraints

Rationally Designed Macrocyclic Peptides as Synergistic Agonists of LPS-Induced Inflammatory Response

Relacin, a novel antibacterial agent targeting the Stringent Response

Rosetta FlexPepDock ab-initio: simultaneous folding, docking and refinement of peptides onto their receptors

Rosetta FlexPepDock web server--high resolution modeling of peptide-protein interactions

Rosetta predictions in CASP5: successes, failures, and prospects for complete automation.

RosettaDock in CAPRI rounds 6-12

Structural basis for UFM1 transfer from UBA5 to UFC1

Structure-Based Identification of HDAC8 Non-histone Substrates

Structure-based prediction of HDAC6 substrates validated by enzymatic assay reveals determinants of promiscuity and detects new potential substrates

Sub-angstrom modeling of complexes between flexible peptides and globular proteins.

The Escherichia coli extracellular death factor EDF induces the endoribonucleolytic activities of the toxins MazF and ChpBK.

The SV40 capsid is stabilized by a conserved pentapeptide hinge of the major capsid protein VP1.

The structural basis of peptide-protein binding strategies.

The structure, dynamics, and energetics of protein adsorption-lessons learned from adsorption of statherin to hydroxyapatite

Trans protein splicing of cyanobacterial split inteins in endogenous and exogenous combinations.

Ubiquitination and degradation of the inhibitors of NF-kappaB

Versatile communication strategies among tandem WW domain repeats

Yeast aconitase mitochondrial import is modulated by interactions of its C and N terminal domains and Ssa1/2 (Hsp70).

c-Abl phosphorylates E6AP and regulates its E3 ubiquitin ligase activity