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Lista de obras de Rob C Hoeben

A Transductionally Retargeted Adenoviral Vector for Virotherapy of Her2/neu-Expressing Prostate Cancer ⬇️

artículo científico publicado el 12 de octubre de 2011

A cathepsin-cleavage site between the adenovirus capsid protein IX and a tumor-targeting ligand improves targeted transduction.

artículo científico publicado en 2011

A dual role of the N-terminal FQQI motif in GLUT4 trafficking

artículo científico publicado en 2009

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

artículo científico publicado en 2014

A lentiviral vector-based adenovirus fiber-pseudotyping approach for expedited functional assessment of candidate retargeted fibers

artículo científico publicado en 2009

A polymorphism in the IL-10 promoter affects autoantibody production and subsequent joint destruction in rheumatoid arthritis.

artículo científico publicado en 2003

A potentially immunologically inert derivative of the reverse tetracycline-controlled transactivator

artículo científico publicado en 2010

A strategy for genetic modification of the spike-encoding segment of human reovirus T3D for reovirus targeting.

artículo científico publicado en 2008

A system for efficient generation of adenovirus protein IX-producing helper cell lines

artículo científico publicado en 2006

ATF3 and Fra1 have opposite functions in JNK- and ERK-dependent DNA damage responses

artículo científico publicado en 2008

Activation or frustration of anti-tumor responses by T-cell-based immune modulation ⬇️

artículo científico publicado el 1 de octubre de 1997

Activin A impairs insulin action in cardiomyocytes via up-regulation of miR-143

artículo científico publicado en 2013

Adenoviral transduction of dendritic cells

scientific article published on 01 January 2005

Adenoviral vectors stimulate glucagon transcription in human mesenchymal stem cells expressing pancreatic transcription factors.

artículo científico publicado en 2012

Adenovirus 5 vector genetically re-targeted by an Affibody molecule with specificity for tumor antigen HER2/neu.

artículo científico publicado en 2007

Adenovirus DNA replication

Adenovirus Receptor Expression in Cancer and Its Multifaceted Role in Oncolytic Adenovirus Therapy

scientific article published on 17 September 2020

Adenovirus targeting to HLA-A1/MAGE-A1-positive tumor cells by fusing a single-chain T-cell receptor with minor capsid protein IX.

artículo científico publicado en 2008

Adenovirus-derived vectors for prostate cancer gene therapy

scientific article published on July 2010

Adipocyte-derived factors impair insulin signaling in differentiated human vascular smooth muscle cells via the upregulation of miR-143.

artículo científico publicado en 2013

Alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 can support immune responses toward tumors overexpressing ganglioside D3 in mice.

artículo científico publicado en 2016

Animal models in virus research: their utility and limitations

artículo científico publicado en 2012

Antibody-Neutralized Reovirus Is Effective in Oncolytic Virotherapy ⬇️

artículo científico publicado en 2018

Arming oncolytic reovirus with GM-CSF gene to enhance immunity

article

Association of the -2849 interleukin-10 promoter polymorphism with autoantibody production and joint destruction in rheumatoid arthritis

article

Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes.

artículo científico publicado en 2017

Baculovirus-assisted Reovirus Infection in Monolayer and Spheroid Cultures of Glioma cells.

artículo científico publicado en 2017

Bioluminescent reporter assay for monitoring ER stress in human beta cells

scientific article published in Scientific Reports

Biosafety of non-human therapeutic viruses in clinical gene therapy

artículo científico publicado en 2013

Cell replacement therapies: is it time to reprogram?

artículo científico publicado en 2014

Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells

artículo científico publicado en 2006

Changing faces in virology: the dutch shift from oncogenic to oncolytic viruses

artículo científico publicado en 2014

Characterization of 911: a new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors.

artículo científico publicado en 1996

Characterization of adenovirus type 5 insertion and deletion mutants encoding altered DNA binding proteins

artículo científico publicado en 1989

Characterization of an immuno 'stealth' derivative of the herpes simplex virus thymidine-kinase gene.

artículo científico publicado en 2006

Characterization of cloned chicken anemia virus DNA that contains all elements for the infectious replication cycle ⬇️

artículo científico publicado el 1 de junio de 1991

Clinical adenoviral gene therapy for prostate cancer

scientific article published on July 2010

Construction and biological activity of a full-length molecular clone of human Torque teno virus (TTV) genotype 6.

artículo científico publicado en 2007

Conversion of mature human β-cells into glucagon-producing α-cells.

artículo científico publicado en 2013

Correction of murine Rag1 deficiency by self-inactivating lentiviral vector-mediated gene transfer.

artículo científico publicado en 2011

Creation of immune 'stealth' genes for gene therapy through fusion with the Gly-Ala repeat of EBNA-1.

artículo científico publicado en 2003

Cross-species transfer of viruses: implications for the use of viral vectors in biomedical research, gene therapy and as live-virus vaccines

artículo científico publicado en 2005

DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1.

artículo científico publicado en 2005

Developing a potentially immunologically inert tetracycline-regulatable viral vector for gene therapy in the peripheral nerve

artículo científico publicado en 2014

Development of an inducible suicide gene system based on human caspase 8.

artículo científico publicado en 2005

Differential expression of LFA-3, Fas and MHC Class I on Ad5- and Ad12-transformed human cells and their susceptibility to lymphokine-activated killer (LAK) cells

artículo científico publicado en 2005

Directed adenovirus evolution using engineered mutator viral polymerases

artículo científico publicado en 2010

Efficient incorporation of a functional hyper-stable single-chain antibody fragment protein-IX fusion in the adenovirus capsid.

artículo científico publicado en 2007

Emergence of viral diseases: mathematical modeling as a tool for infection control, policy and decision making

artículo científico publicado en 2010

Enhanced transduction of CAR-negative cells by protein IX-gene deleted adenovirus 5 vectors.

artículo científico publicado en 2010

Evaluating reporter genes of different luciferases for optimized in vivo bioluminescence imaging of transplanted neural stem cells in the brain

artículo científico publicado en 2013

Exploitation of herpesvirus immune evasion strategies to modify the immunogenicity of human mesenchymal stem cell transplants

artículo científico publicado en 2011

Exploring Reovirus Plasticity for Improving Its Use as Oncolytic Virus

artículo científico publicado en 2016

Expression of functional factor VIII in primary human skin fibroblasts after retrovirus-mediated gene transfer.

artículo científico publicado en 1990

Expression of the blood-clotting factor-VIII cDNA is repressed by a transcriptional silencer located in its coding region.

artículo científico publicado en 1995

Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis.

artículo científico publicado en 2015

Factors impeding efficient expression of factor VIII complementary DNA minigenes.

artículo científico publicado en 1997

Ganciclovir nucleotides accumulate in mitochondria of rat liver cells expressing the herpes simplex virus thymidine kinase gene

artículo científico publicado en 2003

Gene therapy and cement injection for restabilization of loosened hip prostheses

artículo científico publicado en 2008

Gene therapy for the treatment of hip prosthesis loosening: adverse events in a phase 1 clinical study

artículo científico publicado en 2008

Gene therapy in The Netherlands: highlights from the Low Countries

artículo científico publicado en 2007

Gene therapy with apoptin induces regression of xenografted human hepatomas

artículo científico publicado en 2002

Genetically engineered human islets protected from CD8-mediated autoimmune destruction in vivo

scientific article published on 21 May 2013

Herpesvirus microRNAs for use in gene therapy immune-evasion strategies

artículo científico publicado en 2017

Heterogeneous reovirus susceptibility in human glioblastoma stem-like cell cultures.

artículo científico publicado en 2013

Highly efficient ex vivo lentiviral transduction of primary human pancreatic exocrine cells

scientific article published on 01 November 2019

Highly efficient transduction of human monocyte-derived dendritic cells with subgroup B fiber-modified adenovirus vectors enhances transgene-encoded antigen presentation to cytotoxic T cells.

artículo científico publicado en 2001

How not to be seen: immune-evasion strategies in gene therapy.

artículo científico publicado en 2007

Human B cells fail to secrete type I interferons upon cytoplasmic DNA exposure

artículo científico publicado en 2017

Human adenovirus type 35 vector for gene therapy of brain cancer: improved transduction and bypass of pre-existing anti-vector immunity in cancer patients.

artículo científico publicado en 2006

Hydrocortisone stimulates the development of oligodendrocytes in primary glial cultures and affects glucose metabolism and lipid synthesis in these cultures

artículo científico publicado en 1987

Identification and characterisation of citrullinated antigen-specific B cells in peripheral blood of patients with rheumatoid arthritis.

artículo científico publicado en 2015

Immune responses against adenoviral vectors and their transgene products: a review of strategies for evasion.

artículo científico publicado en 2004

Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons.

artículo científico publicado en 2018

In cis inhibition of antigen processing by the latency-associated nuclear antigen I of Kaposi sarcoma herpes virus

artículo científico publicado en 2006

Inactivation of the Moloney murine leukemia virus long terminal repeat in murine fibroblast cell lines is associated with methylation and dependent on its chromosomal position ⬇️

artículo científico publicado el 1 de febrero de 1991

Increased glia-specific transgene expression with glial fibrillary acidic protein promoters containing multiple enhancer elements

artículo científico publicado en 2006

Increased vulnerability of pre-existing atherosclerosis in ApoE-deficient mice following adenovirus-mediated Fas ligand gene transfer

article

Induction of atherosclerotic plaque rupture in apolipoprotein E-/- mice after adenovirus-mediated transfer of p53.

artículo científico publicado en 2002

Insertion vectors for gene therapy.

artículo científico publicado en 2000

Integrating gene delivery and gene-editing technologies by adenoviral vector transfer of optimized CRISPR-Cas9 components

artículo científico publicado en 2020

Internalization of oncolytic reovirus by human dendritic cell carriers protects the virus from neutralization

artículo científico publicado en 2011

Intronic SMCHD1 variants in FSHD: testing the potential for CRISPR-Cas9 genome editing

scientific article published on 01 November 2019

Invasion of synoviocytes is inhibited by gene transfer of TNF-BP or IL10 in an in vitro invasion model

artículo científico publicado en 2001

Isolated human islets contain a distinct population of mesenchymal stem cells

artículo científico publicado en 2010

Isolated-organ perfusion for local gene delivery: efficient adenovirus-mediated gene transfer into the liver.

artículo científico publicado en 1997

Isolation of reovirus T3D mutants capable of infecting human tumor cells independent of junction adhesion molecule-A.

artículo científico publicado en 2012

KRAS(D13) Promotes apoptosis of human colorectal tumor cells by ReovirusT3D and oxaliplatin but not by tumor necrosis factor-related apoptosis-inducing ligand

scientific article published on 01 May 2006

Lentiviral vectors efficiently transduce quiescent mature 3T3-L1 adipocytes

artículo científico publicado en 2004

Locally-delivered T-cell-derived cellular vehicles efficiently track and deliver adenovirus delta24-RGD to infiltrating glioma

artículo científico publicado en 2014

Mammalian orthoreovirus T3D infects U-118 MG cell spheroids independent of junction adhesion molecule-A.

artículo científico publicado en 2014

Mitogen-activated protein kinase (MAPK) phosphatase-1 and -4 attenuate p38 MAPK during dexamethasone-induced insulin resistance in 3T3-L1 adipocytes

artículo científico publicado en 2004

Modification of mammalian reoviruses for use as oncolytic agents

artículo científico publicado en 2009

Molecular imaging and treatment of malignant gliomas following adenoviral transfer of the herpes simplex virus-thymidine kinase gene and the somatostatin receptor subtype 2 gene

artículo científico publicado en 2004

NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice-A Novel in Vivo Imaging Platform

artículo científico publicado en 2020

Neuroregenerative effects of lentiviral vector-mediated GDNF expression in reimplanted ventral roots

artículo científico publicado en 2008

New helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses.

artículo científico publicado en 1998

New role of signal peptide peptidase to liberate C-terminal peptides for MHC class I presentation

artículo científico publicado en 2013

Non-Human Primate-Derived Adenoviruses for Future Use as Oncolytic Agents?

scientific article published on 08 July 2020

Non-human viruses developed as therapeutic agent for use in humans

scientific article published on 11 May 2011

Off-label prescription of genetically modified organism medicines in europe: emerging conflicts of interest?

artículo científico

Oncolytic Reovirus Infection Is Facilitated by the Autophagic Machinery. ⬇️

artículo científico publicado en 2017

Optimization of short-term transgene expression by sodium butyrate and ubiquitous chromatin opening elements (UCOEs).

artículo científico publicado en 2007

Optimizing reporter constructs for in vivo bioluminescence imaging of interferon-γ stimulated mesenchymal stromal cells

artículo científico publicado en 2014

Origin, fate, and function of epicardium-derived cells (EPDCs) in normal and abnormal cardiac development

artículo científico publicado en 2007

P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells

artículo científico publicado en 2003

Photodynamic inactivation of retroviruses by phthalocyanines: the effects of sulphonation, metal ligand and fluoride

artículo científico publicado el 30 de abril de 1992

Polycistronic lentivirus induced pluripotent stem cells from skin biopsies after long term storage, blood outgrowth endothelial cells and cells from milk teeth

artículo científico publicado en 2013

Pre-surgical neoadjuvant oncolytic virotherapy confers protection against rechallenge in a murine model of breast cancer

artículo científico publicado en 2019

Preconditioning of the tumor microenvironment with oncolytic reovirus converts CD3-bispecific antibody treatment into effective immunotherapy

artículo científico publicado en 2020

Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.

artículo científico publicado en 2015

Protective anti-tumor immunity induced by vaccination with recombinant adenoviruses encoding multiple tumor-associated cytotoxic T lymphocyte epitopes in a string-of-beads fashion

artículo científico publicado en 1997

Reappraisal of biosafety risks posed by PERVs in xenotransplantation

artículo científico publicado en 2008

Relaxed template specificity in fowl adenovirus 1 DNA replication initiation

artículo científico publicado en 2006

Replacement of native adenovirus receptor-binding sites with a new attachment moiety diminishes hepatic tropism and enhances bioavailability in mice

artículo científico publicado en 2008

Replicating reoviruses with a transgene replacing the codons for the head domain of the viral spike

artículo científico publicado en 2015

Safety of recombinant adenoviruses produced on adenovirus-transformed human cells.

artículo científico publicado en 2001

Sensitization to apoptosis underlies KrasD12-dependent oncolysis of murine C26 colorectal carcinoma cells by reovirus T3D.

artículo científico publicado en 2005

Serpina1 (alpha1-AT) is synthesized in the osteoblastic stem cell niche

artículo científico publicado en 2009

Severe hepatic dysfunction after adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene and ganciclovir administration.

artículo científico publicado en 1998

Side effects of suicide gene therapy.

artículo científico publicado en 2004

Spacers increase the accessibility of peptide ligands linked to the carboxyl terminus of adenovirus minor capsid protein IX

artículo científico publicado en 2004

State and prospects of gene therapy for the hemophilias

artículo científico publicado en 1995

Successful RAG1-SCID gene therapy depends on the level of RAG1 expression.

artículo científico publicado en 2014

Targeting malignant gliomas with a glial fibrillary acidic protein (GFAP)-selective oncolytic adenovirus

artículo científico publicado en 2007

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

artículo científico publicado en 2008

The 45-kDa form of Pdx-1 does not result from post-translational modifications

artículo científico publicado en 2008

The Epstein-Barr Virus Glycoprotein gp150 Forms an Immune-Evasive Glycan Shield at the Surface of Infected Cells

artículo científico publicado en 2016

The adenovirus capsid: major progress in minor proteins

artículo científico publicado en 2005

The coiled-coil domain of the adenovirus type 5 protein IX is dispensable for capsid incorporation and thermostability

artículo científico publicado en 2005

The human clotting factor VIII cDNA contains an autonomously replicating sequence consensus- and matrix attachment region-like sequence that binds a nuclear factor, represses heterologous gene expression, and mediates the transcriptional effects of

scientific article published on 01 August 1996

The nested open reading frame in the Epstein-Barr virus nuclear antigen-1 mRNA encodes a protein capable of inhibiting antigen presentation in cis.

artículo científico publicado en 2007

The p38 mitogen-activated protein kinase inhibitor SB203580 reduces glucose turnover by the glucose transporter-4 of 3T3-L1 adipocytes in the insulin-stimulated state

artículo científico publicado en 2005

The protective effect of cardiac gene transfer of CuZn-sod in comparison with the cardioprotector monohydroxyethylrutoside against doxorubicin-induced cardiotoxicity in cultured cells.

artículo científico publicado en 2003

The stability of envelope-pseudotyped lentiviral vectors

scientific article published on 24 September 2020

Toll-like receptor triggering augments activation of human mast cells by anti-citrullinated protein antibodies

scientific article published on 12 May 2014

Toward gene therapy for hemophilia A: long-term persistence of factor VIII-secreting fibroblasts after transplantation into immunodeficient mice.

artículo científico publicado en 1993

Toward gene therapy in haemophilia A: retrovirus-mediated transfer of a factor VIII gene into murine haematopoietic progenitor cells

artículo científico publicado en 1992

Towards gene therapy for colorectal liver metastases.

artículo científico publicado en 1998

Towards gene therapy in prosthesis loosening: efficient killing of interface cells by gene-directed enzyme prodrug therapy with nitroreductase and the prodrug CB1954.

artículo científico publicado en 2005

Towards integrating vectors for gene therapy: expression of functional bacteriophage MuA and MuB proteins in mammalian cells.

artículo científico publicado en 2000

Truncating the i-leader open reading frame enhances release of human adenovirus type 5 in glioma cells

artículo científico publicado en 2011

Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates

artículo científico publicado en 2009

[Gene therapy for hemophilia: feasible in principle but not yet clinically applicable]

scientific article published on 01 April 1998

[Stem cells: therapeutic applications and experimental techniques]

scientific article published on 01 January 2011

β-Cell Generation: Can Rodent Studies Be Translated to Humans?

artículo científico publicado en 2011

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