Lista de obras - Anthony S. Don - Dominio Público Uruguay

A Novel Function of Sphingosine Kinase 2 in the Metabolism of Sphinga-4,14-Diene Lipids

scientific article published on 08 June 2020

A Phosphorylatable Sphingosine Analog Induces Airway Smooth Muscle Cytostasis and Reverses Airway Hyperresponsiveness in Experimental Asthma

scientific article published on 21 February 2017

A fluorescent assay for ceramide synthase activity.

artículo científico publicado en 2012

A lipid binding domain in sphingosine kinase 2

artículo científico publicado en 2009

A metabolic shift favoring sphingosine 1-phosphate at the expense of ceramide controls glioblastoma angiogenesis.

artículo científico publicado en 2013

A peptide trivalent arsenical inhibits tumor angiogenesis by perturbing mitochondrial function in angiogenic endothelial cells.

artículo científico publicado en 2003

A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism

artículo científico publicado en 2018

A three-step assay for ceramide synthase activity using a fluorescent substrate and HPLC.

artículo científico publicado en 2014

ABCA8 stimulates sphingomyelin production in oligodendrocytes

artículo científico publicado en 2013

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.

artículo científico publicado en 2016

Age-Dependent Changes to Sphingolipid Balance in the Human Hippocampus are Gender-Specific and May Sensitize to Neurodegeneration

artículo científico publicado en 2018

Altered lipid levels provide evidence for myelin dysfunction in multiple system atrophy

artículo científico publicado en 2014

Assaying Ceramide Synthase Activity In Vitro and in Living Cells Using Liquid Chromatography-Mass Spectrometry.

artículo científico publicado en 2016

Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice

artículo científico publicado en 2017

Contextual fear conditioning is enhanced in mice lacking functional sphingosine kinase 2.

artículo científico publicado en 2017

Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control

artículo científico publicado en 2022

Deletion of sphingosine kinase 1 ameliorates hepatic steatosis in diet-induced obese mice: Role of PPARγ.

artículo científico publicado en 2015

Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice.

artículo científico publicado en 2018

Disparate in vivo efficacy of FTY720 in xenograft models of Philadelphia positive and negative B-lineage acute lymphoblastic leukemia

artículo científico publicado en 2012

Elimination of a hydroxyl group in FTY720 dramatically improves the phosphorylation rate.

artículo científico publicado en 2010

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

artículo científico publicado en 2006

Fluorescent Assays for Ceramide Synthase Activity

artículo científico publicado en 2016

High FA2H and UGT8 transcript levels predict hydroxylated hexosylceramide accumulation in lung adenocarcinoma

scientific article published on 13 August 2019

Increased sphingosine 1-phosphate mediates inflammation and fibrosis in tubular injury in diabetic nephropathy.

artículo científico publicado en 2015

Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease

artículo científico publicado en 2016

Loss of sphingosine kinase 1 predisposes to the onset of diabetes via promoting pancreatic β-cell death in diet-induced obese mice.

artículo científico publicado en 2013

Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis.

scientific article published on 23 January 2014

MMSAT: Automated Quantification of Metabolites in Selected Reaction Monitoring Experiments ⬇️

artículo científico publicado el 13 de diciembre de 2011

Mass and relative elution time profiling: two-dimensional analysis of sphingolipids in Alzheimer's disease brains.

artículo científico publicado en 2011

Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains.

artículo científico publicado en 2005

Mitochondria as cancer drug targets.

artículo científico publicado en 2004

Noninvasive imaging of cell death using an Hsp90 ligand.

artículo científico publicado en 2011

Phagocytosis of IgG-coated polystyrene beads by macrophages induces and requires high membrane order.

artículo científico publicado en 2011

Re-configuration of sphingolipid metabolism by oncogenic transformation

artículo científico publicado en 2014

Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: A beneficial role for very long-chain sphingolipid species.

artículo científico publicado en 2016

Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2

scientific article published on 11 September 2020

Sphingosine 1-phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes

artículo científico publicado en 2019

Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease

artículo científico publicado en 2019

Synthesis and biological evaluation of analogs of AAL(S) for use as ceramide synthase 1 inhibitors

artículo científico publicado en 2015

The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity.

artículo científico publicado en 2013

Treatment with a sphingosine analog after the inception of house dust mite-induced airway inflammation alleviates key features of experimental asthma.

artículo científico publicado en 2015

Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy

artículo científico publicado en 2017

Lista de obras de Anthony S. Don

A Novel Function of Sphingosine Kinase 2 in the Metabolism of Sphinga-4,14-Diene Lipids

A Phosphorylatable Sphingosine Analog Induces Airway Smooth Muscle Cytostasis and Reverses Airway Hyperresponsiveness in Experimental Asthma

A fluorescent assay for ceramide synthase activity.

A lipid binding domain in sphingosine kinase 2

A metabolic shift favoring sphingosine 1-phosphate at the expense of ceramide controls glioblastoma angiogenesis.

A peptide trivalent arsenical inhibits tumor angiogenesis by perturbing mitochondrial function in angiogenic endothelial cells.

A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism

A three-step assay for ceramide synthase activity using a fluorescent substrate and HPLC.

ABCA8 stimulates sphingomyelin production in oligodendrocytes

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.

Age-Dependent Changes to Sphingolipid Balance in the Human Hippocampus are Gender-Specific and May Sensitize to Neurodegeneration

Altered lipid levels provide evidence for myelin dysfunction in multiple system atrophy

Assaying Ceramide Synthase Activity In Vitro and in Living Cells Using Liquid Chromatography-Mass Spectrometry.

Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice

Contextual fear conditioning is enhanced in mice lacking functional sphingosine kinase 2.

Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control

Deletion of sphingosine kinase 1 ameliorates hepatic steatosis in diet-induced obese mice: Role of PPARγ.

Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice.

Disparate in vivo efficacy of FTY720 in xenograft models of Philadelphia positive and negative B-lineage acute lymphoblastic leukemia

Elimination of a hydroxyl group in FTY720 dramatically improves the phosphorylation rate.

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

Fluorescent Assays for Ceramide Synthase Activity

High FA2H and UGT8 transcript levels predict hydroxylated hexosylceramide accumulation in lung adenocarcinoma

Increased sphingosine 1-phosphate mediates inflammation and fibrosis in tubular injury in diabetic nephropathy.

Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease

Loss of sphingosine kinase 1 predisposes to the onset of diabetes via promoting pancreatic β-cell death in diet-induced obese mice.

Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis.

MMSAT: Automated Quantification of Metabolites in Selected Reaction Monitoring Experiments ⬇️

Mass and relative elution time profiling: two-dimensional analysis of sphingolipids in Alzheimer's disease brains.

Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains.

Mitochondria as cancer drug targets.

Noninvasive imaging of cell death using an Hsp90 ligand.

Phagocytosis of IgG-coated polystyrene beads by macrophages induces and requires high membrane order.

Re-configuration of sphingolipid metabolism by oncogenic transformation

Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: A beneficial role for very long-chain sphingolipid species.

Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2

Sphingosine 1-phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes

Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease

Synthesis and biological evaluation of analogs of AAL(S) for use as ceramide synthase 1 inhibitors

The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity.

Treatment with a sphingosine analog after the inception of house dust mite-induced airway inflammation alleviates key features of experimental asthma.

Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy