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Lista de obras de David I Finkelstein

A novel approach to rapidly prevent age-related cognitive decline

artículo científico publicado en 2013

A time-course analysis of changes in cerebral metal levels following a controlled cortical impact

artículo científico publicado en 2015

Acute Neurotoxicity Models of Prion Disease.

artículo científico publicado en 2018

Age modulates the injury-induced metallomic profile in the brain.

artículo científico publicado en 2017

Age-dependent effects of A53T alpha-synuclein on behavior and dopaminergic function

artículo científico publicado en 2013

An intact membrane is essential for small extracellular vesicle-induced modulation of α-synuclein fibrillization

artículo científico publicado en 2020

Analogues of desferrioxamine B designed to attenuate iron-mediated neurodegeneration: synthesis, characterisation and activity in the MPTP-mouse model of Parkinson's disease

artículo científico publicado en 2017

Cell infiltration into a 3D electrospun fiber and hydrogel hybrid scaffold implanted in the brain.

artículo científico publicado en 2015

Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease.

artículo científico publicado en 2013

Characterising the brain metalloproteome in Down syndrome patients with concomitant Alzheimer's pathology

artículo científico publicado en 2020

Chronic isolation stress is associated with increased colonic and motor symptoms in the A53T mouse model of Parkinson's disease

artículo científico publicado en 2019

Clioquinol Improves Cognitive, Motor Function, and Microanatomy of the Alpha-Synuclein hA53T Transgenic Mice

artículo científico publicado en 2015

Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse

artículo científico publicado en 2015

Comparative Study of Metal Quantification in Neurological Tissue Using Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry Imaging and X-ray Fluorescence Microscopy

artículo científico publicado en 2015

Correction: Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging

Correction: Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging

artículo científico publicado en 2016

Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model

artículo científico publicado en 2011

Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc

artículo científico publicado en 2019

Effects of Neonatal Iron Feeding and Chronic Clioquinol Administration on the Parkinsonian Human A53T Transgenic Mouse

artículo científico publicado en 2015

Enduring Elevations of Hippocampal Amyloid Precursor Protein and Iron Are Features of β-Amyloid Toxicity and Are Mediated by Tau

artículo científico publicado en 2015

Enhancing neurite outgrowth from primary neurones and neural stem cells using thermoresponsive hydrogel scaffolds for the repair of spinal cord injury.

artículo científico publicado en 2009

Excessive early-life dietary exposure: a potential source of elevated brain iron and a risk factor for Parkinson's disease

artículo científico publicado en 2017

Exercise and physical activity for people with Progressive Supranuclear Palsy: a systematic review

artículo científico publicado en 2019

Ferroptosis and cell death mechanisms in Parkinson's disease.

artículo científico publicado en 2017

Fibrillar α-synuclein toxicity depends on functional lysosomes

artículo científico publicado en 2020

GSK-3β dysregulation contributes to parkinson's-like pathophysiology with associated region-specific phosphorylation and accumulation of tau and α-synuclein

artículo científico publicado en 2014

Glia and zinc in ageing and Alzheimer's disease: a mechanism for cognitive decline?

artículo científico

Graphene Functionalized Scaffolds Reduce the Inflammatory Response and Supports Endogenous Neuroblast Migration when Implanted in the Adult Brain

artículo científico publicado en 2016

H5N1 influenza virus pathogenesis in genetically diverse mice is mediated at the level of viral load

artículo científico publicado en 2011

High order W02-reactive stable oligomers of amyloid-β are produced in vivo and in vitro via dialysis and filtration of synthetic amyloid-β monomer

artículo científico publicado en 2015

Implantation of functionalized thermally gelling xyloglucan hydrogel within the brain: associated neurite infiltration and inflammatory response

artículo científico publicado en 2010

In vivo prion models and the disconnection between transmissibility and neurotoxicity

artículo científico publicado en 2017

Increased Ndfip1 in the substantia nigra of Parkinsonian brains is associated with elevated iron levels

artículo científico publicado en 2014

Interactions of metals and Apolipoprotein E in Alzheimer's disease

artículo científico publicado en 2014

Iron Regulates Apolipoprotein E Expression and Secretion in Neurons and Astrocytes

artículo científico publicado en 2016

Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson's disease

artículo científico publicado en 2014

Is early-life iron exposure critical in neurodegeneration?

artículo científico

Large-scale sequence analysis of avian influenza isolates.

artículo científico publicado en 2006

Lithium suppression of tau induces brain iron accumulation and neurodegeneration. ⬇️

artículo científico

Metal chaperones prevent zinc-mediated cognitive decline

artículo científico publicado en 2014

Metal chaperones: a novel therapeutic strategy for brain injury?

scientific article published on 03 December 2018

Metals in Alzheimer's and Parkinson's Disease: Relevance to Dementia with Lewy Bodies

artículo científico publicado en 2016

Mice deficient for the chromosome 21 ortholog Itsn1 exhibit vesicle-trafficking abnormalities.

artículo científico publicado en 2008

Migration and Differentiation of Neural Stem Cells Diverted From the Subventricular Zone by an Injectable Self-Assembling β-Peptide Hydrogel

artículo científico publicado en 2019

Misfolded α-synuclein causes hyperactive respiration without functional deficit in live neuroblastoma cells

scientific article published on 17 January 2020

Modulating Protein Phosphatase 2A Rescues Disease Phenotype in Neurodegenerative Tauopathies

artículo científico publicado en 2018

Motor and cognitive deficits in aged tau knockout mice in two background strains.

artículo científico publicado en 2014

N-acetylcysteine modulates glutamatergic dysfunction and depressive behavior in Huntington's disease.

artículo científico publicado en 2016

Parkinson's disease iron deposition caused by nitric oxide-induced loss of β-amyloid precursor protein.

artículo científico publicado en 2015

Pathogenic mechanisms of prion protein, amyloid-β and α-synuclein misfolding: the prion concept and neurotoxicity of protein oligomers.

artículo científico publicado en 2016

Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma

artículo científico publicado en 2014

Pramipexole restores depressed transmission in the ventral hippocampus following MPTP-lesion

artículo científico publicado en 2017

Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species

artículo científico publicado en 2018

Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

artículo científico publicado en 2008

Reduced striatal vesicular monoamine transporter 2 in REM sleep behavior disorder: imaging prodromal parkinsonism

artículo científico publicado en 2020

Regional iron distribution and soluble ferroprotein profiles in the healthy human brain

artículo científico publicado en 2019

Rescue of the Friedreich ataxia knockout mutation in transgenic mice containing an FXN-EGFP genomic reporter

artículo científico publicado en 2014

Restoration of intestinal function in an MPTP model of Parkinson's Disease

artículo científico publicado en 2016

Role of metal ions in the cognitive decline of Down syndrome.

artículo científico publicado en 2014

Serotonergic markers in Parkinson's disease and levodopa-induced dyskinesias

artículo científico publicado en 2015

Targeting metals rescues the phenotype in an animal model of tauopathy

scientific article published on 01 September 2018

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.

artículo científico publicado en 2012

Tau protein: relevance to Parkinson's disease

artículo científico publicado en 2010

The effect of dopamine on MPTP-induced rotarod disability.

artículo científico publicado en 2013

The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease

artículo científico publicado en 2012

The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's disease

artículo científico publicado en 2017

The role of lipids in α-synuclein misfolding and neurotoxicity.

artículo científico publicado en 2019

Therapeutic applications of chelating drugs in iron metabolic disorders of the brain and retina

artículo científico publicado en 2020

Three-dimensional elemental bio-imaging of Fe, Zn, Cu, Mn and P in a 6-hydroxydopamine lesioned mouse brain

artículo científico publicado en 2010

Transferrin protects against Parkinsonian neurotoxicity and is deficient in Parkinson's substantia nigra

artículo científico publicado en 2016

Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimer's Disease.

artículo científico publicado en 2017

Trehalose elevates brain zinc levels following controlled cortical impact in a mouse model of traumatic brain injury

scientific article published on 01 June 2018

Trehalose improves traumatic brain injury-induced cognitive impairment

artículo científico publicado en 2017

Type-1 interferons contribute to the neuroinflammatory response and disease progression of the MPTP mouse model of Parkinson's disease.

artículo científico publicado en 2016

Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway

artículo científico publicado en 2017

Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway

scientific article published on 28 June 2019

Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging

artículo científico publicado en 2015

Zinc affects the proteolytic stability of Apolipoprotein E in an isoform-dependent way.

artículo científico publicado en 2015

l-3,4-dihydroxyphenylalanine (l-DOPA) modulates brain iron, dopaminergic neurodegeneration and motor dysfunction in iron overload and mutant alpha-synuclein mouse models of Parkinson's disease

scientific article published on 28 March 2019

α-Synuclein Regulates Development and Function of Cholinergic Enteric Neurons in the Mouse Colon

scientific article published on 06 November 2019

α-Synuclein transgenic mice reveal compensatory increases in Parkinson's disease-associated proteins DJ-1 and parkin and have enhanced α-synuclein and PINK1 levels after rotenone treatment.

artículo científico publicado en 2010

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