Lista de obras - Jeffrey B Carroll - Dominio Público Uruguay

A fully humanized transgenic mouse model of Huntington disease.

artículo científico publicado en 2012

Activated caspase-6 and caspase-6-cleaved fragments of huntingtin specifically colocalize in the nucleus

artículo científico publicado en 2008

Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease

artículo científico publicado en 2009

Automated deformation analysis in the YAC128 Huntington disease mouse model

artículo científico publicado en 2007

CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup

artículo científico publicado en 2009

Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation.

artículo científico publicado en 2007

Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes

artículo científico publicado en 2010

Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease

artículo científico publicado en 2008

Early Detection of Apathetic Phenotypes in Huntington's Disease Knock-in Mice Using Open Source Tools.

artículo científico publicado en 2018

HAP40 orchestrates huntingtin structure for differential interaction with polyglutamine expanded exon 1

preprint

HDBuzz: empowering patients through accessible education.

artículo científico publicado en 2011

Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

artículo científico publicado en 2021

Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease.

artículo científico publicado en 2011

Natural history of disease in the YAC128 mouse reveals a discrete signature of pathology in Huntington disease

artículo científico publicado en 2011

Parvoviral nuclear import: bypassing the host nuclear-transport machinery

artículo científico publicado en 2006

Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease

artículo científico publicado en 2017

Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain

artículo científico publicado en 2006

Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene / allele-specific silencing of mutant huntingtin

artículo científico publicado en 2011

Single-nucleus RNA-seq reveals dysregulation of striatal cell identity due to Huntington’s disease mutations

scholarly article

Stool is a sensitive and noninvasive source of DNA for monitoring expansion in repeat expansion disease mouse models

scholarly article

Transcriptional regulatory networks underlying gene expression changes in Huntington's disease

artículo científico publicado en 2018

Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14.

artículo científico publicado en 2011

Lista de obras de Jeffrey B Carroll

A fully humanized transgenic mouse model of Huntington disease.

Activated caspase-6 and caspase-6-cleaved fragments of huntingtin specifically colocalize in the nucleus

Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease

Automated deformation analysis in the YAC128 Huntington disease mouse model

CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup

Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation.

Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes

Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease

Early Detection of Apathetic Phenotypes in Huntington's Disease Knock-in Mice Using Open Source Tools.

HAP40 orchestrates huntingtin structure for differential interaction with polyglutamine expanded exon 1

HDBuzz: empowering patients through accessible education.

Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease.

Natural history of disease in the YAC128 mouse reveals a discrete signature of pathology in Huntington disease

Parvoviral nuclear import: bypassing the host nuclear-transport machinery

Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease

Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain

Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene / allele-specific silencing of mutant huntingtin

Single-nucleus RNA-seq reveals dysregulation of striatal cell identity due to Huntington’s disease mutations

Stool is a sensitive and noninvasive source of DNA for monitoring expansion in repeat expansion disease mouse models

Transcriptional regulatory networks underlying gene expression changes in Huntington's disease

Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14.