Lista de obras - Birgit Sawitzki - Dominio Público Uruguay

Abdominal Wall Transplantation: Skin as a Sentinel Marker for Rejection

artículo científico publicado en 2015

Age and gender leucocytes variances and references values generated using the standardized ONE-Study protocol

artículo científico publicado en 2016

Allo-specific T-cells encoding for viral IL-10 exert strong immunomodulatory effects in vitro but fail to prevent graft rejection.

artículo científico publicado en 2005

Allogeneic Liver Transplantation and Subsequent Syngeneic Hepatocyte Transplantation in a Rat Model: Proof of Concept for in vivo Tissue Engineering

artículo científico publicado en 2016

Allogeneic gene-modified tumor cells (RCC-26/IL-7/CD80) as a vaccine in patients with metastatic renal cell cancer: a clinical phase-I study

artículo científico publicado en 2010

Allogeneic partially HLA-matched dendritic cells pulsed with autologous tumor cell lysate as a vaccine in metastatic renal cell cancer: a clinical phase I/II study

artículo científico publicado en 2013

Anti-CD4-mediated selection of Treg in vitro - in vitro suppression does not predict in vivo capacity to prevent graft rejection

artículo científico publicado en 2008

Antigen-specific expansion of human regulatory T cells as a major tolerance mechanism against mucosal fungi.

artículo científico publicado en 2013

Application of cultured human regulatory T cells requires preclinical in vivo evaluation

artículo científico publicado en 2012

Autoimmunity and transplantation: a meeting at the crossroads in Berlin.

artículo científico publicado en 2008

B-cell-related biomarkers of tolerance are up-regulated in rejection-free kidney transplant recipients.

artículo científico publicado en 2013

Bag-1 up-regulation in anti-CD4 mAb-treated allo-activated T cell confers resistance to activation-induced cell death (AICD).

artículo científico publicado en 2002

CD30 discriminates heat shock protein 60-induced FOXP3+ CD4+ T cells with a regulatory phenotype.

artículo científico publicado en 2010

CD45RA distinguishes CD4+CD25+CD127-/low TSDR demethylated regulatory T cell subpopulations with differential stability and susceptibility to tacrolimus mediated inhibition of suppression.

artículo científico publicado en 2016

Can we use biomarkers and functional assays to implement personalized therapies in transplantation?

artículo científico publicado en 2009

Cellular energy metabolism in T-lymphocytes

artículo científico publicado en 2014

Central Role of CD45RA- Foxp3hi Memory Regulatory T Cells in Clinical Kidney Transplantation Tolerance

artículo científico publicado en 2015

Clinical Use of Tolerogenic Dendritic Cells-Harmonization Approach in European Collaborative Effort

artículo científico publicado en 2015

Clinical relevance of the de novo production of anti-HLA antibodies following intestinal and multivisceral transplantation.

artículo científico publicado en 2014

Complement activation induces excessive T cell cytotoxicity in severe COVID-19

artículo científico publicado en 2021

Control of TNF-induced dendritic cell maturation by hybrid-type N-glycans

artículo científico publicado en 2011

Correction: Differences in CD44 Surface Expression Levels and Function Discriminates IL-17 and IFN-γ Producing Helper T Cells

artículo científico publicado en 2015

Cutting Edge: Immunological Consequences and Trafficking of Human Regulatory Macrophages Administered to Renal Transplant Recipients

artículo científico publicado en 2011

Demethylation of the TSDR is a marker of squamous cell carcinoma in transplant recipients

artículo científico publicado en 2014

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells

artículo científico publicado en 2012

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans

artículo científico publicado en 2010

Dextran Sulfate Facilitates Anti-CD4 mAb-Induced Long-Term Rat Cardiac Allograft Survival After Prolonged Cold Ischemia

Differences in CD44 Surface Expression Levels and Function Discriminates IL-17 and IFN-γ Producing Helper T Cells

artículo científico publicado en 2015

Differential expression and function of α-mannosidase I in stimulated naive and memory CD4+ T cells

artículo científico publicado en 2011

Early Enrichment and Restitution of the Peripheral Blood Treg Pool Is Associated With Rejection-Free Stable Immunosuppression After Liver Transplantation

artículo científico publicado en 2016

Effect of induction therapy on the expression of molecular markers associated with rejection and tolerance

artículo científico publicado en 2015

Effector T cell subclasses associate with tumor burden in neurofibromatosis type 1 patients

artículo científico publicado en 2016

Elevation of CD4+ differentiated memory T cells is associated with acute cellular and antibody-mediated rejection after liver transplantation

artículo científico publicado en 2013

Epigenomic Profiling of Human CD4(+) T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development

artículo científico publicado en 2016

Ex vivo gene transfer of viral interleukin-10 to BB rat islets: no protection after transplantation to diabetic BB rats

scientific article published on July 2007

Exhaustive differentiation of alloreactive CD8+ T cells: critical for determination of graft acceptance or rejection

artículo científico publicado en 2008

Expansion of memory-type CD8+ T cells correlates with the failure of early immunosuppression withdrawal after cadaver liver transplantation using high-dose ATG induction and rapamycin.

artículo científico publicado en 2013

Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney

article

Expression of tolerance associated gene-1, a mitochondrial protein inhibiting T cell activation, can be used to predict response to immune modulating therapies

scientific journal article

Fas ligand breaks tolerance to self-antigens and induces tumor immunity mediated by antibodies

artículo científico publicado en 2002

Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus

artículo científico publicado en 2012

Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells

artículo científico publicado en 2011

Generation of HCMV-specific T-cell lines from seropositive solid-organ-transplant recipients for adoptive T-cell therapy

artículo científico publicado en 2009

Generation of highly effective and stable murine alloreactive Treg cells by combined anti-CD4 mAb, TGF-β, and RA treatment.

artículo científico publicado en 2013

Guidelines for the use of flow cytometry and cell sorting in immunological studies

artículo científico publicado en 2017

High weight differences between donor and recipient affect early kidney graft function--a role for enhanced IL-6 signaling.

artículo científico publicado en 2009

Human CD45RA(-) FoxP3(hi) Memory-Type Regulatory T Cells Show Distinct TCR Repertoires With Conventional T Cells and Play an Important Role in Controlling Early Immune Activation.

artículo científico publicado en 2015

Hurdles in therapy with regulatory T cells

artículo científico

IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo

artículo científico publicado en 2005

IFN-gamma regulation in anti-CD4 antibody-induced T cell unresponsiveness

artículo científico publicado en 2004

IRF1 and BATF-transcription factors that set the epigenetic landscape for Tr1 cell differentiation?

artículo científico publicado en 2017

Identification of gene markers for the prediction of allograft rejection or permanent acceptance.

artículo científico publicado en 2007

Immune monitoring as prerequisite for transplantation tolerance trials

artículo científico publicado en 2017

Immune monitoring in renal transplantation: The search for biomarkers

artículo científico publicado en 2016

Impact of hepatic rearterialization on reperfusion injury and outcome after mouse liver transplantation

artículo científico publicado en 2003

Induction of allograft tolerance by monoclonal CD3 antibodies: a matter of timing.

artículo científico publicado en 2012

Influence of combined treatment of low dose rapamycin and cyclosporin A on corneal allograft survival

artículo científico publicado en 2010

Interferon Gamma: Friend or Foe?

Interferon γ: a crucial role in the function of induced regulatory T cells in vivo

Intragraft and Systemic Immune Parameters Discriminating Between Rejection and Long-Term Graft Function in a Preclinical Model of Intestinal Transplantation

artículo científico publicado en 2016

Intragraft mechanisms associated with the immunosuppressive versus the tolerogenic effect of CD3 antibodies in a mouse model of islet allografts.

artículo científico publicado en 2013

Isolation, characterization and cold storage of cells isolated from diseased explanted livers

artículo científico publicado en 2017

Liver Transplant Patients With Operational Tolerance: What Can the Graft Itself Tell Us?

artículo científico publicado en 2015

Low-dose cyclosporine mediates donor hyporesponsiveness in a fully mismatched rat kidney transplant model

artículo científico publicado en 2012

Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus

artículo científico publicado en 2015

Mechanisms and rescue strategies of calcineurin inhibitor mediated tolerance abrogation induced by anti-CD4 mAb treatment.

artículo científico publicado en 2013

Microglial activation milieu controls regulatory T cell responses.

artículo científico publicado en 2013

Molecular Analysis of Renal Allograft Biopsies-More Than a Nice Toy for Researchers?

artículo científico publicado en 2013

Molecular Characterization of Acute Cellular Rejection Occurring During Intentional Immunosuppression Withdrawal in Liver Transplantation.

artículo científico publicado en 2015

Monitoring tolerance and rejection in organ transplant recipients.

artículo científico publicado en 2011

No prolongation of skin allograft survival by immunoproteasome inhibition in mice.

artículo científico publicado en 2017

Non-HLA Antibodies May Accelerate Immune Responses After Intestinal and Multivisceral Transplantation

artículo científico publicado en 2016

Peripheral biomarkers for individualizing immunosuppression in transplantation--regulatory T cells

artículo científico publicado en 2012

Permanent CNI treatment for prevention of renal allograft rejection in sensitized hosts can be replaced by regulatory T cells

artículo científico publicado en 2012

Pretransplant immune risk assessment.

artículo científico publicado en 2009

Prevention of graft-versus-host disease by adoptive T regulatory therapy is associated with active repression of peripheral blood Toll-like receptor 5 mRNA expression

artículo científico publicado en 2013

Prospective assessment of antidonor cellular alloreactivity is a tool for guidance of immunosuppression in kidney transplantation.

artículo científico publicado en 2013

Rat Cytomegalovirus Infection Interferes with Anti-CD4 mAb-(RIB 5/2) Mediated Tolerance and Induces Chronic Allograft Damage

Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans

artículo científico publicado en 2016

Sequential Targeting of CD52 and TNF Allows Early Minimization Therapy in Kidney Transplantation: From a Biomarker to Targeting in a Proof-Of-Concept Trial.

artículo científico publicado en 2017

Serum biomarkers for neurofibromatosis type 1 and early detection of malignant peripheral nerve-sheath tumors

artículo científico publicado en 2013

Short-term TNF-alpha inhibition reduces short-term and long-term inflammatory changes post-ischemia/reperfusion in rat intestinal transplantation

scientific journal article

Standardized Multi-Color Flow Cytometry and Computational Biomarker Discovery

artículo científico publicado en 2016

State of the art on the research for biomarkers allowing individual, tailor-made minimization of immunosuppression

artículo científico publicado en 2010

Synovial and peripheral blood CD4+FoxP3+ T cells in spondyloarthritis.

artículo científico publicado en 2011

TCAIM decreases T cell priming capacity of dendritic cells by inhibiting TLR-induced Ca2+ influx and IL-2 production

artículo científico publicado en 2015

TGFβ-dependent expression of PD-1 and PD-L1 controls CD8(+) T cell anergy in transplant tolerance

artículo científico publicado en 2016

Targeting of macrophage activity by adenovirus-mediated intragraft overexpression of TNFRp55-Ig, IL-12p40, and vIL-10 ameliorates adenovirus-mediated chronic graft injury, whereas stimulation of macrophages by overexpression of IFN-gamma accelerates

artículo científico publicado en 2003

The mitochondrial protein TCAIM regulates activation of T cells and thereby promotes tolerance induction of allogeneic transplants

artículo científico publicado en 2014

The use of novel diagnostics to individualize immunosuppression following transplantation

artículo científico publicado en 2015

Tolerogenic effect of fiber tract injury: reduced EAE severity following entorhinal cortex lesion

artículo científico publicado en 2006

Transient mTOR inhibition rescues 4-1BB CAR-Tregs from tonic signal-induced dysfunction

artículo científico publicado en 2021

Tregs: application for solid-organ transplantation

artículo científico

Upregulation of Bag-1 by ex vivo gene transfer protects rat livers from ischemia/reperfusion injury

artículo científico publicado en 2002

Wild immunology assessed by multidimensional mass cytometry.

artículo científico publicado en 2016

Lista de obras de Birgit Sawitzki

Abdominal Wall Transplantation: Skin as a Sentinel Marker for Rejection

Age and gender leucocytes variances and references values generated using the standardized ONE-Study protocol

Allo-specific T-cells encoding for viral IL-10 exert strong immunomodulatory effects in vitro but fail to prevent graft rejection.

Allogeneic Liver Transplantation and Subsequent Syngeneic Hepatocyte Transplantation in a Rat Model: Proof of Concept for in vivo Tissue Engineering

Allogeneic gene-modified tumor cells (RCC-26/IL-7/CD80) as a vaccine in patients with metastatic renal cell cancer: a clinical phase-I study

Allogeneic partially HLA-matched dendritic cells pulsed with autologous tumor cell lysate as a vaccine in metastatic renal cell cancer: a clinical phase I/II study

Anti-CD4-mediated selection of Treg in vitro - in vitro suppression does not predict in vivo capacity to prevent graft rejection

Antigen-specific expansion of human regulatory T cells as a major tolerance mechanism against mucosal fungi.

Application of cultured human regulatory T cells requires preclinical in vivo evaluation

Autoimmunity and transplantation: a meeting at the crossroads in Berlin.

B-cell-related biomarkers of tolerance are up-regulated in rejection-free kidney transplant recipients.

Bag-1 up-regulation in anti-CD4 mAb-treated allo-activated T cell confers resistance to activation-induced cell death (AICD).

CD30 discriminates heat shock protein 60-induced FOXP3+ CD4+ T cells with a regulatory phenotype.

CD45RA distinguishes CD4+CD25+CD127-/low TSDR demethylated regulatory T cell subpopulations with differential stability and susceptibility to tacrolimus mediated inhibition of suppression.

Can we use biomarkers and functional assays to implement personalized therapies in transplantation?

Cellular energy metabolism in T-lymphocytes

Central Role of CD45RA- Foxp3hi Memory Regulatory T Cells in Clinical Kidney Transplantation Tolerance

Clinical Use of Tolerogenic Dendritic Cells-Harmonization Approach in European Collaborative Effort

Clinical relevance of the de novo production of anti-HLA antibodies following intestinal and multivisceral transplantation.

Complement activation induces excessive T cell cytotoxicity in severe COVID-19

Control of TNF-induced dendritic cell maturation by hybrid-type N-glycans

Correction: Differences in CD44 Surface Expression Levels and Function Discriminates IL-17 and IFN-γ Producing Helper T Cells

Cutting Edge: Immunological Consequences and Trafficking of Human Regulatory Macrophages Administered to Renal Transplant Recipients

Demethylation of the TSDR is a marker of squamous cell carcinoma in transplant recipients

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans

Dextran Sulfate Facilitates Anti-CD4 mAb-Induced Long-Term Rat Cardiac Allograft Survival After Prolonged Cold Ischemia

Differences in CD44 Surface Expression Levels and Function Discriminates IL-17 and IFN-γ Producing Helper T Cells

Differential expression and function of α-mannosidase I in stimulated naive and memory CD4+ T cells

Early Enrichment and Restitution of the Peripheral Blood Treg Pool Is Associated With Rejection-Free Stable Immunosuppression After Liver Transplantation

Effect of induction therapy on the expression of molecular markers associated with rejection and tolerance

Effector T cell subclasses associate with tumor burden in neurofibromatosis type 1 patients

Elevation of CD4+ differentiated memory T cells is associated with acute cellular and antibody-mediated rejection after liver transplantation

Epigenomic Profiling of Human CD4(+) T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development

Ex vivo gene transfer of viral interleukin-10 to BB rat islets: no protection after transplantation to diabetic BB rats

Exhaustive differentiation of alloreactive CD8+ T cells: critical for determination of graft acceptance or rejection

Expansion of memory-type CD8+ T cells correlates with the failure of early immunosuppression withdrawal after cadaver liver transplantation using high-dose ATG induction and rapamycin.

Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney

Expression of tolerance associated gene-1, a mitochondrial protein inhibiting T cell activation, can be used to predict response to immune modulating therapies

Fas ligand breaks tolerance to self-antigens and induces tumor immunity mediated by antibodies

Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus

Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells

Generation of HCMV-specific T-cell lines from seropositive solid-organ-transplant recipients for adoptive T-cell therapy

Generation of highly effective and stable murine alloreactive Treg cells by combined anti-CD4 mAb, TGF-β, and RA treatment.

Guidelines for the use of flow cytometry and cell sorting in immunological studies

High weight differences between donor and recipient affect early kidney graft function--a role for enhanced IL-6 signaling.

Human CD45RA(-) FoxP3(hi) Memory-Type Regulatory T Cells Show Distinct TCR Repertoires With Conventional T Cells and Play an Important Role in Controlling Early Immune Activation.

Hurdles in therapy with regulatory T cells

IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo

IFN-gamma regulation in anti-CD4 antibody-induced T cell unresponsiveness

IRF1 and BATF-transcription factors that set the epigenetic landscape for Tr1 cell differentiation?

Identification of gene markers for the prediction of allograft rejection or permanent acceptance.

Immune monitoring as prerequisite for transplantation tolerance trials

Immune monitoring in renal transplantation: The search for biomarkers

Impact of hepatic rearterialization on reperfusion injury and outcome after mouse liver transplantation

Induction of allograft tolerance by monoclonal CD3 antibodies: a matter of timing.

Influence of combined treatment of low dose rapamycin and cyclosporin A on corneal allograft survival

Interferon Gamma: Friend or Foe?

Interferon γ: a crucial role in the function of induced regulatory T cells in vivo

Intragraft and Systemic Immune Parameters Discriminating Between Rejection and Long-Term Graft Function in a Preclinical Model of Intestinal Transplantation

Intragraft mechanisms associated with the immunosuppressive versus the tolerogenic effect of CD3 antibodies in a mouse model of islet allografts.

Isolation, characterization and cold storage of cells isolated from diseased explanted livers

Liver Transplant Patients With Operational Tolerance: What Can the Graft Itself Tell Us?

Low-dose cyclosporine mediates donor hyporesponsiveness in a fully mismatched rat kidney transplant model

Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus

Mechanisms and rescue strategies of calcineurin inhibitor mediated tolerance abrogation induced by anti-CD4 mAb treatment.

Microglial activation milieu controls regulatory T cell responses.

Molecular Analysis of Renal Allograft Biopsies-More Than a Nice Toy for Researchers?

Molecular Characterization of Acute Cellular Rejection Occurring During Intentional Immunosuppression Withdrawal in Liver Transplantation.

Monitoring tolerance and rejection in organ transplant recipients.

No prolongation of skin allograft survival by immunoproteasome inhibition in mice.

Non-HLA Antibodies May Accelerate Immune Responses After Intestinal and Multivisceral Transplantation

Peripheral biomarkers for individualizing immunosuppression in transplantation--regulatory T cells

Permanent CNI treatment for prevention of renal allograft rejection in sensitized hosts can be replaced by regulatory T cells

Pretransplant immune risk assessment.

Prevention of graft-versus-host disease by adoptive T regulatory therapy is associated with active repression of peripheral blood Toll-like receptor 5 mRNA expression

Prospective assessment of antidonor cellular alloreactivity is a tool for guidance of immunosuppression in kidney transplantation.

Rat Cytomegalovirus Infection Interferes with Anti-CD4 mAb-(RIB 5/2) Mediated Tolerance and Induces Chronic Allograft Damage

Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans