Lista de obras - Karin J Metzner - Dominio Público Uruguay

A Comprehensive Analysis of Primer IDs to Study Heterogeneous HIV-1 Populations

artículo científico publicado en 2015

A Follow-Up of the Multicenter Collaborative Study on HIV-1 Drug Resistance and Tropism Testing Using 454 Ultra Deep Pyrosequencing

artículo científico publicado en 2016

A Lead-In with Silibinin Prior to Triple-Therapy Translates into Favorable Treatment Outcomes in Difficult-To-Treat HIV/Hepatitis C Coinfected Patients

artículo científico publicado en 2015

A framework for inferring fitness landscapes of patient-derived viruses using quasispecies theory

artículo científico publicado en 2014

A suicide gene approach using the human pro-apoptotic protein tBid inhibits HIV-1 replication

artículo científico publicado en 2011

A truncated form of Nef selected during pathogenic reversion of simian immunodeficiency virus SIVmac239Deltanef increases viral replication

artículo científico publicado en 2003

An international multicenter study on HIV-1 drug resistance testing by 454 ultra-deep pyrosequencing

artículo científico publicado en 2014

Blinded, multicenter comparison of methods to detect a drug-resistant mutant of human immunodeficiency virus type 1 at low frequency

artículo científico publicado en 2006

Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing data

artículo científico publicado en 2012

Changing Trends in International Versus Domestic HCV Transmission in HIV-Positive Men Who Have Sex With Men: A Perspective for the Direct-Acting Antiviral Scale-Up Era

artículo científico publicado en 2019

Characterization of human immunodeficiency virus type 1 (HIV-1) diversity and tropism in 145 patients with primary HIV-1 infection

artículo científico publicado en 2011

Comparison of G-to-A mutation frequencies induced by APOBEC3 proteins in H9 cells and peripheral blood mononuclear cells in the context of impaired processivities of drug-resistant human immunodeficiency virus type 1 reverse transcriptase variants

artículo científico publicado en 2008

Correction to: Optimization and validation of sample preparation for metagenomic sequencing of viruses in clinical samples

artículo científico publicado en 2017

Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality.

artículo científico publicado en 2017

Detection of minor populations of drug-resistant HIV-1 in acute seroconverters.

artículo científico publicado en 2005

Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART

scientific article published on 19 July 2019

EBV renders B cells susceptible to HIV-1 in humanized mice

artículo científico publicado en 2020

Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial

scientific article published on 10 November 2020

Efficacy of lead-in silibinin and subsequent triple therapy in difficult-to-treat HIV/hepatitis C virus-coinfected patients.

artículo científico publicado en 2014

Efficient suppression of minority drug-resistant HIV type 1 (HIV-1) variants present at primary HIV-1 infection by ritonavir-boosted protease inhibitor-containing antiretroviral therapy

artículo científico publicado en 2010

Emergence of Resistance to Integrase Strand Transfer Inhibitors during Dolutegravir Containing Triple-Therapy in a Treatment-Experienced Patient with Pre-Existing M184V/I Mutation

artículo científico publicado en 2020

Emergence of minor populations of human immunodeficiency virus type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions

artículo científico publicado en 2003

Evaluation of CD8+ T-cell and antibody responses following transient increased viraemia in rhesus macaques infected with live, attenuated simian immunodeficiency virus

artículo científico publicado en 2005

Evolution and Diversity of HIV-1 ⬇️

artículo científico publicado el 5 de enero de 2011

Full-length haplotype reconstruction to infer the structure of heterogeneous virus populations

artículo científico publicado en 2014

HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection

artículo científico publicado en 2020

HIV suppression by interleukin-16.

artículo científico publicado en 1995

HIV-1 RNAs are Not Part of the Argonaute 2 Associated RNA Interference Pathway in Macrophages

artículo científico publicado en 2015

Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART

scientific article published on 02 November 2020

Impact of minority nonnucleoside reverse transcriptase inhibitor resistance mutations on resistance genotype after virologic failure

artículo científico publicado en 2012

In Vivo and in Vitro Proteome Analysis of Human Immunodeficiency Virus (HIV)-1-infected, Human CD4+ T Cells

artículo científico publicado en 2017

In-depth analysis of G-to-A hypermutation rate in HIV-1 env DNA induced by endogenous APOBEC3 proteins using massively parallel sequencing

artículo científico publicado en 2010

Incident Hepatitis C Virus Infections in the Swiss HIV Cohort Study: Changes in Treatment Uptake and Outcomes Between 1991 and 2013.

artículo científico publicado en 2015

Inhibition of drug-resistant HIV-1 by RNA interference

artículo científico publicado en 2005

Limited clinical benefit of minority K103N and Y181C-variant detection in addition to routine genotypic resistance testing in antiretroviral therapy-naive patients

artículo científico publicado en 2014

Long-term experimental evolution of HIV-1 reveals effects of environment and mutational history

artículo científico publicado en 2020

Low prevalence of transmitted HIV-1 drug resistance detected by a dried blood spot (DBS)-based next-generation sequencing (NGS) method in newly diagnosed individuals in Cameroon in the years 2015-16.

artículo científico publicado en 2018

Low-frequency drug-resistant HIV-1 and risk of virological failure to first-line NNRTI-based ART: a multicohort European case-control study using centralized ultrasensitive 454 pyrosequencing

artículo científico publicado en 2014

MinVar: A rapid and versatile tool for HIV-1 drug resistance genotyping by deep sequencing

artículo científico publicado en 2016

Mining for pairs: shared clinic visit dates identify steady HIV-positive partnerships.

artículo científico publicado en 2017

Minority K65R variants and early failure of antiretroviral therapy in HIV-1-infected Eritrean immigrant

artículo científico publicado en 2011

Minority quasispecies of drug-resistant HIV-1 that lead to early therapy failure in treatment-naive and -adherent patients

artículo científico publicado en 2009

Molecular characterisation of Lac s 1, the major allergen from lettuce (Lactuca sativa).

artículo científico publicado en 2007

Molecular cloning, expression and characterization of Pru a 1, the major cherry allergen.

artículo científico publicado en 1997

Monocyte-derived macrophages exhibit distinct and more restricted HIV-1 integration site repertoire than CD4(+) T cells

artículo científico publicado en 2016

Next-generation sequencing of HIV-1 RNA genomes: determination of error rates and minimizing artificial recombination

artículo científico publicado en 2013

No Effect of Pegylated Interferon-alpha on Total Hiv-1 DNA Load in HIV-1/HCV Coinfected Patients.

artículo científico publicado en 2018

Noninferiority of Simplified Dolutegravir Monotherapy Compared to Continued Combination Antiretroviral Therapy That Was Initiated During Primary Human Immunodeficiency Virus Infection: A Randomized, Controlled, Multisite, Open-label, Noninferiority

scientific article published on 01 October 2019

Origin of minority drug-resistant HIV-1 variants in primary HIV-1 infection

artículo científico publicado en 2013

Parallel evolution of HIV-1 in a long-term experiment

scientific article published on 28 June 2019

Persistence of drug-resistant HIV-1 and possible implications for antiretroviral therapy

article

Persistence of lamivudine-sensitive HIV-1 quasispecies in the presence of lamivudine in vitro and in vivo.

artículo científico publicado en 2007

Prevalence of key resistance mutations K65R, K103N, and M184V as minority HIV-1 variants in chronically HIV-1 infected, treatment-naïve patients

artículo científico publicado en 2010

Profound depletion of HIV-1 transcription in patients initiating antiretroviral therapy during acute infection

artículo científico publicado en 2010

Rapid decline of anti-hepatitis C virus (HCV) antibodies following early treatment of incident HCV infections in HIV-infected men who have sex with men.

artículo científico publicado en 2018

Rapid selection of drug-resistant HIV-1 during the first months of suppressive ART in treatment-naive patients

article

Rational design of HIV-1 fluorescent hydrolysis probes considering phylogenetic variation and probe performance

artículo científico publicado en 2010

Reappearance of minority K103N HIV-1 variants after interruption of ART initiated during primary HIV-1 infection

artículo científico publicado en 2011

Recovering networks from distance data

Reply to correspondence 'Conserved signatures indicate HIV-1 transmission is under strong selection and thus is not a "stochastic" process' by Gonzalez et al., Retrovirology 2017.

artículo científico publicado en 2017

Simian immunodeficiency virus-specific cytotoxic T lymphocytes and protection against challenge in rhesus macaques immunized with a live attenuated simian immunodeficiency virus vaccine.

artículo científico publicado en 2000

Spontaneous reactivation of latent HIV-1 promoters is linked to the cell cycle as revealed by a genetic-insulators-containing dual-fluorescence HIV-1-based vector.

artículo científico publicado en 2018

Stable HIV-1 reservoirs on dolutegravir maintenance monotherapy: the MONODO study

article

Synthetic pre-microRNAs reveal dual-strand activity of miR-34a on TNF-α.

artículo científico publicado en 2013

Tailored enrichment strategy detects low abundant small noncoding RNAs in HIV-1 infected cells

artículo científico publicado en 2012

Tenofovir treatment augments anti-viral immunity against drug-resistant SIV challenge in chronically infected rhesus macaques

artículo científico publicado en 2006

The antiretroviral potency of emtricitabine is approximately 3-fold higher compared to lamivudine in dual human immunodeficiency virus type 1 infection/competition experiments in vitro

artículo científico publicado en 2010

Tracing HIV-1 strains that imprint broadly neutralizing antibody responses

artículo científico publicado en 2018

Tracing HIV-1 transmission: envelope traits of HIV-1 transmitter and recipient pairs

artículo científico publicado en 2016

Unravelling HIV-1 Latency, One Cell at a Time

artículo científico publicado en 2017

Using longitudinally sampled viral nucleotide sequences to characterize the drivers of HIV-1 transmission

artículo científico publicado en 2020

Viral Diversity Based on Next-Generation Sequencing of HIV-1 Provides Precise Estimates of Infection Recency and Time Since Infection

artículo científico publicado en 2019

Women in the European Virus Bioinformatics Center

artículo científico publicado en 2022

Lista de obras de Karin J Metzner

A Comprehensive Analysis of Primer IDs to Study Heterogeneous HIV-1 Populations

A Follow-Up of the Multicenter Collaborative Study on HIV-1 Drug Resistance and Tropism Testing Using 454 Ultra Deep Pyrosequencing

A Lead-In with Silibinin Prior to Triple-Therapy Translates into Favorable Treatment Outcomes in Difficult-To-Treat HIV/Hepatitis C Coinfected Patients

A framework for inferring fitness landscapes of patient-derived viruses using quasispecies theory

A suicide gene approach using the human pro-apoptotic protein tBid inhibits HIV-1 replication

A truncated form of Nef selected during pathogenic reversion of simian immunodeficiency virus SIVmac239Deltanef increases viral replication

An international multicenter study on HIV-1 drug resistance testing by 454 ultra-deep pyrosequencing

Blinded, multicenter comparison of methods to detect a drug-resistant mutant of human immunodeficiency virus type 1 at low frequency

Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing data

Changing Trends in International Versus Domestic HCV Transmission in HIV-Positive Men Who Have Sex With Men: A Perspective for the Direct-Acting Antiviral Scale-Up Era

Characterization of human immunodeficiency virus type 1 (HIV-1) diversity and tropism in 145 patients with primary HIV-1 infection

Comparison of G-to-A mutation frequencies induced by APOBEC3 proteins in H9 cells and peripheral blood mononuclear cells in the context of impaired processivities of drug-resistant human immunodeficiency virus type 1 reverse transcriptase variants

Correction to: Optimization and validation of sample preparation for metagenomic sequencing of viruses in clinical samples

Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality.

Detection of minor populations of drug-resistant HIV-1 in acute seroconverters.

Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART

EBV renders B cells susceptible to HIV-1 in humanized mice

Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial

Efficacy of lead-in silibinin and subsequent triple therapy in difficult-to-treat HIV/hepatitis C virus-coinfected patients.

Efficient suppression of minority drug-resistant HIV type 1 (HIV-1) variants present at primary HIV-1 infection by ritonavir-boosted protease inhibitor-containing antiretroviral therapy

Emergence of Resistance to Integrase Strand Transfer Inhibitors during Dolutegravir Containing Triple-Therapy in a Treatment-Experienced Patient with Pre-Existing M184V/I Mutation

Emergence of minor populations of human immunodeficiency virus type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions

Evaluation of CD8+ T-cell and antibody responses following transient increased viraemia in rhesus macaques infected with live, attenuated simian immunodeficiency virus

Evolution and Diversity of HIV-1 ⬇️

Full-length haplotype reconstruction to infer the structure of heterogeneous virus populations

HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection

HIV suppression by interleukin-16.

HIV-1 RNAs are Not Part of the Argonaute 2 Associated RNA Interference Pathway in Macrophages

Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART

Impact of minority nonnucleoside reverse transcriptase inhibitor resistance mutations on resistance genotype after virologic failure

In Vivo and in Vitro Proteome Analysis of Human Immunodeficiency Virus (HIV)-1-infected, Human CD4+ T Cells

In-depth analysis of G-to-A hypermutation rate in HIV-1 env DNA induced by endogenous APOBEC3 proteins using massively parallel sequencing

Incident Hepatitis C Virus Infections in the Swiss HIV Cohort Study: Changes in Treatment Uptake and Outcomes Between 1991 and 2013.

Inhibition of drug-resistant HIV-1 by RNA interference

Limited clinical benefit of minority K103N and Y181C-variant detection in addition to routine genotypic resistance testing in antiretroviral therapy-naive patients

Long-term experimental evolution of HIV-1 reveals effects of environment and mutational history

Low prevalence of transmitted HIV-1 drug resistance detected by a dried blood spot (DBS)-based next-generation sequencing (NGS) method in newly diagnosed individuals in Cameroon in the years 2015-16.

Low-frequency drug-resistant HIV-1 and risk of virological failure to first-line NNRTI-based ART: a multicohort European case-control study using centralized ultrasensitive 454 pyrosequencing

MinVar: A rapid and versatile tool for HIV-1 drug resistance genotyping by deep sequencing

Mining for pairs: shared clinic visit dates identify steady HIV-positive partnerships.

Minority K65R variants and early failure of antiretroviral therapy in HIV-1-infected Eritrean immigrant

Minority quasispecies of drug-resistant HIV-1 that lead to early therapy failure in treatment-naive and -adherent patients

Molecular characterisation of Lac s 1, the major allergen from lettuce (Lactuca sativa).

Molecular cloning, expression and characterization of Pru a 1, the major cherry allergen.

Monocyte-derived macrophages exhibit distinct and more restricted HIV-1 integration site repertoire than CD4(+) T cells

Next-generation sequencing of HIV-1 RNA genomes: determination of error rates and minimizing artificial recombination

No Effect of Pegylated Interferon-alpha on Total Hiv-1 DNA Load in HIV-1/HCV Coinfected Patients.

Noninferiority of Simplified Dolutegravir Monotherapy Compared to Continued Combination Antiretroviral Therapy That Was Initiated During Primary Human Immunodeficiency Virus Infection: A Randomized, Controlled, Multisite, Open-label, Noninferiority

Origin of minority drug-resistant HIV-1 variants in primary HIV-1 infection

Parallel evolution of HIV-1 in a long-term experiment

Persistence of drug-resistant HIV-1 and possible implications for antiretroviral therapy

Persistence of lamivudine-sensitive HIV-1 quasispecies in the presence of lamivudine in vitro and in vivo.

Prevalence of key resistance mutations K65R, K103N, and M184V as minority HIV-1 variants in chronically HIV-1 infected, treatment-naïve patients

Profound depletion of HIV-1 transcription in patients initiating antiretroviral therapy during acute infection

Rapid decline of anti-hepatitis C virus (HCV) antibodies following early treatment of incident HCV infections in HIV-infected men who have sex with men.

Rapid selection of drug-resistant HIV-1 during the first months of suppressive ART in treatment-naive patients

Rational design of HIV-1 fluorescent hydrolysis probes considering phylogenetic variation and probe performance

Reappearance of minority K103N HIV-1 variants after interruption of ART initiated during primary HIV-1 infection

Recovering networks from distance data

Reply to correspondence 'Conserved signatures indicate HIV-1 transmission is under strong selection and thus is not a "stochastic" process' by Gonzalez et al., Retrovirology 2017.

Simian immunodeficiency virus-specific cytotoxic T lymphocytes and protection against challenge in rhesus macaques immunized with a live attenuated simian immunodeficiency virus vaccine.

Spontaneous reactivation of latent HIV-1 promoters is linked to the cell cycle as revealed by a genetic-insulators-containing dual-fluorescence HIV-1-based vector.

Stable HIV-1 reservoirs on dolutegravir maintenance monotherapy: the MONODO study

Synthetic pre-microRNAs reveal dual-strand activity of miR-34a on TNF-α.

Tailored enrichment strategy detects low abundant small noncoding RNAs in HIV-1 infected cells

Tenofovir treatment augments anti-viral immunity against drug-resistant SIV challenge in chronically infected rhesus macaques

The antiretroviral potency of emtricitabine is approximately 3-fold higher compared to lamivudine in dual human immunodeficiency virus type 1 infection/competition experiments in vitro

Tracing HIV-1 strains that imprint broadly neutralizing antibody responses

Tracing HIV-1 transmission: envelope traits of HIV-1 transmitter and recipient pairs

Unravelling HIV-1 Latency, One Cell at a Time

Using longitudinally sampled viral nucleotide sequences to characterize the drivers of HIV-1 transmission

Viral Diversity Based on Next-Generation Sequencing of HIV-1 Provides Precise Estimates of Infection Recency and Time Since Infection

Women in the European Virus Bioinformatics Center