Lista de obras - Alexandre F. Stewart - Dominio Público Uruguay

9p21 and the genetic revolution for coronary artery disease.

artículo científico publicado en 2011

9p21.3 Coronary Artery Disease Risk Variants Disrupt TEAD Transcription Factor-Dependent Transforming Growth Factor β Regulation of p16 Expression in Human Aortic Smooth Muscle Cells

artículo científico publicado en 2015

A common allele on chromosome 9 associated with coronary heart disease

artículo científico publicado en 2007

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

artículo científico publicado en 2015

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

artículo científico publicado en 2009

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

artículo científico publicado en 2009

A genomic revolution for cardiovascular disease-a progress report at five years

scientific article published on 01 June 2011

Adiposity significantly modifies genetic risk for dyslipidemia.

artículo científico publicado en 2014

Alpha1-adrenergic receptor subtype mRNAs are differentially regulated by alpha1-adrenergic and other hypertrophic stimuli in cardiac myocytes in culture and in vivo. Repression of alpha1B and alpha1D but induction of alpha1C.

artículo científico publicado en 1996

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

artículo científico publicado en 2019

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

artículo científico publicado en 2020

Clinical and genetic association of serum ceruloplasmin with cardiovascular risk.

artículo científico publicado en 2011

Clonal isolation of different strains of mouse mammary tumor virus-like DNA sequences from both the breast tumors and non-Hodgkin's lymphomas of individual patients diagnosed with both malignancies.

artículo científico publicado en 2004

Cloning of the rat alpha 1C-adrenergic receptor from cardiac myocytes. alpha 1C, alpha 1B, and alpha 1D mRNAs are present in cardiac myocytes but not in cardiac fibroblasts.

artículo científico publicado en 1994

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

artículo científico publicado en 2010

Dabrafenib, an inhibitor of RIP3 kinase-dependent necroptosis, reduces ischemic brain injury.

artículo científico publicado en 2018

Distribution of alpha 1C-adrenergic receptor mRNA in adult rat tissues by RNase protection assay and comparison with alpha 1B and alpha 1D.

artículo científico publicado en 1994

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies

artículo científico publicado en 2011

Extracellular ATP-dependent upregulation of the transcription cofactor LMO4 promotes neuron survival from hypoxia

artículo científico publicado en 2007

From genes to regenerative medicine: approaches in development.

artículo científico publicado en 2008

Functional analysis of the chromosome 9p21.3 coronary artery disease risk locus.

artículo científico publicado en 2009

Functional characterization of a promoter polymorphism that drives ACSL5 gene expression in skeletal muscle and associates with diet-induced weight loss

artículo científico publicado en 2009

Functional genomics of the 9p21.3 locus for atherosclerosis: clarity or confusion?

artículo científico

Gene dosage of the common variant 9p21 predicts severity of coronary artery disease

artículo científico publicado en 2010

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

artículo científico publicado en 2010

Genetics of coronary artery disease in the 21st century.

artículo científico publicado en 2012

Genomics in Cardiovascular Disease ⬇️

artículo científico publicado el 21 de marzo de 2013

Genomics in coronary artery disease: past, present and future

artículo científico publicado en 2010

Genomics: Is It Ready for Primetime? ⬇️

artículo científico publicado el 1 de enero de 2012

Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors

artículo científico publicado en 2020

IRF2BP2 3'UTR Polymorphism Increases Coronary Artery Calcification in Men

artículo científico publicado en 2021

IRF2BP2 is a skeletal and cardiac muscle-enriched ischemia-inducible activator of VEGFA expression.

artículo científico publicado en 2010

IRF2BP2-deficient microglia block the anxiolytic effect of enhanced postnatal care.

artículo científico publicado en 2017

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

artículo científico publicado en 2011

Identification of a novel muscle A-type lamin-interacting protein (MLIP)

artículo científico publicado en 2011

Identification of human homologues of the mouse mammary tumor virus receptor.

artículo científico publicado en 2002

Improved Prediction of Cardiovascular Disease Based on a Panel of Single Nucleotide Polymorphisms Identified Through Genome-Wide Association Studies ⬇️

artículo científico publicado el 21 de agosto de 2010

Increased genetic risk for obesity in premature coronary artery disease.

artículo científico publicado en 2015

Interferon regulatory factor 2 binding protein 2: a new player of the innate immune response for stroke recovery

artículo científico publicado en 2017

Interferon-γ activates expression of p15 and p16 regardless of 9p21.3 coronary artery disease risk genotype.

artículo científico publicado en 2012

Is atherosclerosis fundamental to human aging? Lessons from ancient mummies.

artículo científico publicado en 2014

Kinesin family member 6 variant Trp719Arg does not associate with angiographically defined coronary artery disease in the Ottawa Heart Genomics Study

artículo científico publicado en 2009

LMO4 is essential for paraventricular hypothalamic neuronal activity and calcium channel expression to prevent hyperphagia

artículo científico publicado en 2014

LMO4 is required to maintain hypothalamic insulin signaling.

artículo científico publicado en 2014

LMO4 mRNA stability is regulated by extracellular ATP in F11 cells.

artículo científico publicado en 2007

Lack of association of chromosome 9p21.3 genotype with cardiovascular function in persons with stable coronary artery disease: The heart and soul study

scientific article published on 05 April 2009

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

artículo científico publicado en 2011

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Left ventricular and myocardial function in mice expressing constitutively pseudophosphorylated cardiac troponin I.

artículo científico publicado en 2009

Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

artículo científico publicado en 2017

Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury.

artículo científico publicado en 2017

MMTV-related env sequences in human breast tumor.

artículo científico publicado en 2003

Making Sense of Genome-Wide Association Studies

artículo científico publicado en 2014

Mammalian vestigial-like 2, a cofactor of TEF-1 and MEF2 transcription factors that promotes skeletal muscle differentiation

artículo científico publicado en 2002

Mouse DTEF-1 (ETFR-1, TEF-5) is a transcriptional activator in alpha 1-adrenergic agonist-stimulated cardiac myocytes.

artículo científico publicado en 2002

Mouse mammary tumor virus (MMTV)-like DNA sequences in the breast tumors of father, mother, and daughter.

artículo científico publicado en 2008

Mouse viruses and human disease

article

Neuronal Protein Tyrosine Phosphatase 1B Hastens Amyloid β-Associated Alzheimer's Disease in Mice

artículo científico publicado en 2020

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

scientific article published on 12 October 2016

Partitioning the heritability of coronary artery disease highlights the importance of immune-mediated processes and epigenetic sites associated with transcriptional activity

artículo científico publicado en 2017

Personalized genomic medicine: a future prerequisite for the prevention of coronary artery disease.

artículo científico publicado en 2006

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

artículo científico publicado en 2012

Plasma PCSK9 levels are elevated with acute myocardial infarction in two independent retrospective angiographic studies

artículo científico publicado en 2014

Prevalence and correlates of diabetes in South asian indians in the United States: findings from the metabolic syndrome and atherosclerosis in South asians living in america study and the multi-ethnic study of atherosclerosis.

artículo científico publicado en 2010

RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies

artículo científico publicado en 2011

Rare copy number variation discovery and cross-disorder comparisons identify risk genes for ADHD.

artículo científico publicado en 2011

Recent success in the discovery of coronary artery disease genes.

artículo científico

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study

artículo científico publicado en 2017

Revisiting the MMTV Zoonotic Hypothesis to Account for Geographic Variation in Breast Cancer Incidence

artículo científico publicado en 2022

STrengthening the REporting of Genetic Association studies (STREGA)—an extension of the STROBE statement

article

Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation

artículo científico publicado en 2006

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

artículo científico publicado en 2019

TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters

artículo científico publicado en 2002

TEF-1 transcription factors regulate activity of the mouse mammary tumor virus LTR.

artículo científico publicado en 2002

Tail-anchored membrane protein SLMAP is a novel regulator of cardiac function at the sarcoplasmic reticulum

artículo científico publicado en 2011

The LIM domain only 4 protein is a metabolic responsive inhibitor of protein tyrosine phosphatase 1B that controls hypothalamic leptin signaling.

artículo científico publicado en 2013

The genetics of coronary artery disease

article

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

artículo científico publicado en 2015

Transcription Factor RTEF-1 Mediates α 1 -Adrenergic Reactivation of the Fetal Gene Program in Cardiac Myocytes ⬇️

artículo científico publicado el 13 de julio de 1998

Transcription cofactor Vgl-2 is required for skeletal muscle differentiation.

artículo científico publicado en 2004

Transcriptomic Signature of Atherosclerosis in the Peripheral Blood: Fact or Fiction?

artículo científico publicado en 2016

Troponin I protein kinase C phosphorylation sites and ventricular function

artículo científico publicado en 2004

Vgl-4, a novel member of the vestigial-like family of transcription cofactors, regulates alpha1-adrenergic activation of gene expression in cardiac myocytes.

artículo científico publicado en 2004

Why did ancient people have atherosclerosis?: from autopsies to computed tomography to potential causes

artículo científico publicado en 2014

Lista de obras de Alexandre F. Stewart

9p21 and the genetic revolution for coronary artery disease.

9p21.3 Coronary Artery Disease Risk Variants Disrupt TEAD Transcription Factor-Dependent Transforming Growth Factor β Regulation of p16 Expression in Human Aortic Smooth Muscle Cells

A common allele on chromosome 9 associated with coronary heart disease

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

A genomic revolution for cardiovascular disease-a progress report at five years

Adiposity significantly modifies genetic risk for dyslipidemia.

Alpha1-adrenergic receptor subtype mRNAs are differentially regulated by alpha1-adrenergic and other hypertrophic stimuli in cardiac myocytes in culture and in vivo. Repression of alpha1B and alpha1D but induction of alpha1C.

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

Clinical and genetic association of serum ceruloplasmin with cardiovascular risk.

Clonal isolation of different strains of mouse mammary tumor virus-like DNA sequences from both the breast tumors and non-Hodgkin's lymphomas of individual patients diagnosed with both malignancies.

Cloning of the rat alpha 1C-adrenergic receptor from cardiac myocytes. alpha 1C, alpha 1B, and alpha 1D mRNAs are present in cardiac myocytes but not in cardiac fibroblasts.

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

Dabrafenib, an inhibitor of RIP3 kinase-dependent necroptosis, reduces ischemic brain injury.

Distribution of alpha 1C-adrenergic receptor mRNA in adult rat tissues by RNase protection assay and comparison with alpha 1B and alpha 1D.

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies

Extracellular ATP-dependent upregulation of the transcription cofactor LMO4 promotes neuron survival from hypoxia

From genes to regenerative medicine: approaches in development.

Functional analysis of the chromosome 9p21.3 coronary artery disease risk locus.

Functional characterization of a promoter polymorphism that drives ACSL5 gene expression in skeletal muscle and associates with diet-induced weight loss

Functional genomics of the 9p21.3 locus for atherosclerosis: clarity or confusion?

Gene dosage of the common variant 9p21 predicts severity of coronary artery disease

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

Genetics of coronary artery disease in the 21st century.

Genomics in Cardiovascular Disease ⬇️

Genomics in coronary artery disease: past, present and future

Genomics: Is It Ready for Primetime? ⬇️

Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors

IRF2BP2 3'UTR Polymorphism Increases Coronary Artery Calcification in Men

IRF2BP2 is a skeletal and cardiac muscle-enriched ischemia-inducible activator of VEGFA expression.

IRF2BP2-deficient microglia block the anxiolytic effect of enhanced postnatal care.

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

Identification of a novel muscle A-type lamin-interacting protein (MLIP)

Identification of human homologues of the mouse mammary tumor virus receptor.

Improved Prediction of Cardiovascular Disease Based on a Panel of Single Nucleotide Polymorphisms Identified Through Genome-Wide Association Studies ⬇️

Increased genetic risk for obesity in premature coronary artery disease.

Interferon regulatory factor 2 binding protein 2: a new player of the innate immune response for stroke recovery

Interferon-γ activates expression of p15 and p16 regardless of 9p21.3 coronary artery disease risk genotype.

Is atherosclerosis fundamental to human aging? Lessons from ancient mummies.

Kinesin family member 6 variant Trp719Arg does not associate with angiographically defined coronary artery disease in the Ottawa Heart Genomics Study

LMO4 is essential for paraventricular hypothalamic neuronal activity and calcium channel expression to prevent hyperphagia

LMO4 is required to maintain hypothalamic insulin signaling.

LMO4 mRNA stability is regulated by extracellular ATP in F11 cells.

Lack of association of chromosome 9p21.3 genotype with cardiovascular function in persons with stable coronary artery disease: The heart and soul study

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

Large-scale association analysis identifies new risk loci for coronary artery disease

Left ventricular and myocardial function in mice expressing constitutively pseudophosphorylated cardiac troponin I.

Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury.

MMTV-related env sequences in human breast tumor.

Making Sense of Genome-Wide Association Studies

Mammalian vestigial-like 2, a cofactor of TEF-1 and MEF2 transcription factors that promotes skeletal muscle differentiation

Mouse DTEF-1 (ETFR-1, TEF-5) is a transcriptional activator in alpha 1-adrenergic agonist-stimulated cardiac myocytes.

Mouse mammary tumor virus (MMTV)-like DNA sequences in the breast tumors of father, mother, and daughter.

Mouse viruses and human disease

Neuronal Protein Tyrosine Phosphatase 1B Hastens Amyloid β-Associated Alzheimer's Disease in Mice

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

Partitioning the heritability of coronary artery disease highlights the importance of immune-mediated processes and epigenetic sites associated with transcriptional activity

Personalized genomic medicine: a future prerequisite for the prevention of coronary artery disease.

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Plasma PCSK9 levels are elevated with acute myocardial infarction in two independent retrospective angiographic studies

Prevalence and correlates of diabetes in South asian indians in the United States: findings from the metabolic syndrome and atherosclerosis in South asians living in america study and the multi-ethnic study of atherosclerosis.

RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies

Rare copy number variation discovery and cross-disorder comparisons identify risk genes for ADHD.

Recent success in the discovery of coronary artery disease genes.

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study

Revisiting the MMTV Zoonotic Hypothesis to Account for Geographic Variation in Breast Cancer Incidence

STrengthening the REporting of Genetic Association studies (STREGA)—an extension of the STROBE statement

Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters

TEF-1 transcription factors regulate activity of the mouse mammary tumor virus LTR.

Tail-anchored membrane protein SLMAP is a novel regulator of cardiac function at the sarcoplasmic reticulum

The LIM domain only 4 protein is a metabolic responsive inhibitor of protein tyrosine phosphatase 1B that controls hypothalamic leptin signaling.

The genetics of coronary artery disease

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

Transcription Factor RTEF-1 Mediates α 1 -Adrenergic Reactivation of the Fetal Gene Program in Cardiac Myocytes ⬇️