Lista de obras - Michael Groessl - Dominio Público Uruguay

A calibration framework for the determination of accurate collision cross sections of polyanions using polyoxometalate standards

artículo científico publicado en 2018

A comprehensive urinary steroid analysis strategy using two-dimensional gas chromatography - time of flight mass spectrometry

scientific article published on 01 September 2018

A glucose derivative as natural alternative to the cyclohexane-1,2-diamine ligand in the anticancer drug oxaliplatin?

artículo científico publicado en 2007

A novel cytotoxic cerium complex: aquatrichloridobis(1,10-phenanthroline)cerium(III) (KP776). Synthesis, characterization, behavior in H2O, binding towards biomolecules, and antiproliferative activity

artículo científico publicado en 2009

A novel framework for molecular characterization of atmospherically relevant organic compounds based on collision cross section and mass-to-charge ratio

scholarly article

A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core

artículo científico publicado en 2011

Anthracene-tethered ruthenium(II) arene complexes as tools to visualize the cellular localization of putative organometallic anticancer compounds

artículo científico publicado en 2012

Anticancer metallodrug research analytically painting the “omics” picture—current developments and future trends ⬇️

artículo científico publicado el 16 de octubre de 2012

Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs ⬇️

artículo científico publicado el 21 de julio de 2013

Bioanalytical and biophysical techniques for the elucidation of the mode of action of metal-based drugs

artículo científico publicado en 2011

CZE-ICP-MS as a tool for studying the hydrolysis of ruthenium anticancer drug candidates and their reactivity towards the DNA model compound dGMP.

artículo científico publicado en 2007

Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: a novel approach for the analysis of anticancer metallodrugs in human serum and plasma

artículo científico publicado en 2008

Cellular uptake and subcellular distribution of ruthenium-based metallodrugs under clinical investigation versus cisplatin

artículo científico publicado en 2011

Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets

artículo científico publicado en 2013

Characterization of Two Novel Variants of the Steroidogenic Acute Regulatory Protein Identified in a Girl with Classic Lipoid Congenital Adrenal Hyperplasia

scientific article published on 27 August 2020

Collision cross sections of negative cluster ions of phosphoric acid in N2 determined by drift tube ion mobility and their use in travelling wave ion mobility

artículo científico publicado en 2019

Combination of metallomics and proteomics to study the effects of the metallodrug RAPTA-T on human cancer cells

artículo científico publicado en 2012

Comparison of UHPLC-ESI-MS and Hadamard transform atmospheric pressure ion mobility-ESI-MS for rapid profiling of isomeric flavonoids

artículo científico publicado en 2014

Concentration and Chemical Stability of Commercially Available Insulins: A High-Resolution Mass Spectrometry Study

artículo científico publicado en 2020

DOSY NMR, X-ray Structural and Ion-Mobility Mass Spectrometric Studies on Electron-Deficient and Electron-Rich M6L4 Coordination Cages

article

Elucidation of the interactions of an anticancer ruthenium complex in clinical trials with biomolecules utilizing capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry. Short communication

artículo científico publicado en 2008

Greener synthesis of new ammonium ionic liquids and their potential as extracting agents

High resolution ion mobility-mass spectrometry for separation and identification of isomeric lipids

artículo científico publicado en 2015

High-Resolution Ion Mobility Spectrometry for Rapid Cannabis Potency Testing.

artículo científico publicado en 2018

Highly Oxygenated Multifunctional Compounds in α-Pinene Secondary Organic Aerosol.

artículo científico publicado en 2017

How high-resolution techniques enable reliable steroid identification and quantification

scientific article published on 27 September 2018

In vitro anticancer activity and biologically relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands

artículo científico publicado en 2008

Interactions of a novel ruthenium-based anticancer drug (KP1019 or FFC14a) with serum proteins--significance for the patient

artículo científico publicado en 2005

Ion mobility spectrometry–mass spectrometry (IMS–MS) for on- and offline analysis of atmospheric gas and aerosol species

article

Ion mobility–mass spectrometry of supramolecular complexes and assemblies

KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients

artículo científico publicado en 2008

Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity

artículo científico publicado en 2014

Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules

artículo científico publicado en 2011

Mass Spectrometric and Theoretical Study of Polyiodides: The Connection between Solid State, Solution, and Gas Phases

scientific article published on 01 September 2011

Metal-Based Inhibition of Poly(ADP-ribose) Polymerase − The Guardian Angel of DNA ⬇️

artículo científico publicado el 3 de marzo de 2011

Multinuclear cytotoxic metallodrugs: physicochemical characterization and biological properties of novel heteronuclear gold-titanium complexes

artículo científico publicado en 2011

Nanoscalic silver possesses broad-spectrum antimicrobial activities and exhibits fewer toxicological side effects than silver sulfadiazine

scholarly article by Oliver Brandt et al published May 2012 in Nanomedicine: Nanotechnology, Biology and Medicine

New Insights into the Chemistry of the Antineoplastic Lanthanum Complex Tris(1,10-phenanthroline)tris(thiocyanato-κN)lanthanum(III) (KP772) and Its Interaction with Biomolecules

Premature adrenarche in girls is characterized by enhanced 17,20-lyase and 17β-hydroxysteroid dehydrogenase activities

scientific article published on 31 August 2020

Profiling of the human monocytic cell secretome by quantitative label-free mass spectrometry identifies stimulus-specific cytokines and proinflammatory proteins

artículo científico publicado en 2012

Proteins as possible targets for cytotoxic trans-platinum(II) complexes with aliphatic amine ligands: Further exceptions to the DNA paradigm

artículo científico publicado en 2010

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts

artículo científico publicado en 2014

Quantitative Fragmentation Model for Bottom-Up Shotgun Lipidomics

scientific article published on 05 September 2019

Rapid quantification of insulin degludec by immunopurification combined with liquid chromatography high-resolution mass spectrometry

artículo científico publicado en 2020

Reactivity of anticancer metallodrugs with serum proteins: new insights from size exclusion chromatography-ICP-MS and ESI-MS

artículo científico publicado en 2010

Response Profiling Using Shotgun Proteomics Enables Global Metallodrug Mechanisms of Action To Be Established.

artículo científico publicado en 2016

Reversion of Structure-Activity Relationships of Antitumor Platinum Complexes by Acetoxime but Not Hydroxylamine Ligands

scientific article published on 18 October 2006

Revisiting Steroidogenic Pathways in the Human Placenta and Primary Human Trophoblast Cells

artículo científico publicado en 2021

Ruthenium versus platinum: interactions of anticancer metallodrugs with duplex oligonucleotides characterised by electrospray ionisation mass spectrometry

artículo científico publicado en 2010

Short-Term Fasting Attenuates Overall Steroid Hormone Biosynthesis in Healthy Young Women

scientific article published on 06 May 2022

Simultaneous endo and exo Complex Formation of Pyridine[4]arene Dimers with Neutral and Anionic Guests.

artículo científico publicado en 2017

Steroid identification via deep learning retention time predictions and two-dimensional gas chromatography-high resolution mass spectrometry

scientific article published on 28 October 2019

Structure-activity relationships for NAMI-A-type complexes (HL)[trans-RuCl4L(S-dmso)ruthenate(III)] (L = imidazole, indazole, 1,2,4-triazole, 4-amino-1,2,4-triazole, and 1-methyl-1,2,4-triazole): aquation, redox properties, protein binding, and anti

artículo científico publicado en 2007

Superchiral Pd3 L6 Coordination Complex and Its Reversible Structural Conversion into Pd3 L3 Cl6 Metallocycles.

artículo científico publicado en 2015

Synthesis and characterization of a new class of anti-angiogenic agents based on ruthenium clusters

artículo científico publicado en 2013

The first example of MEEKC-ICP-MS coupling and its application for the analysis of anticancer platinum complexes

artículo científico publicado en 2010

The metalation of hen egg white lysozyme impacts protein stability as shown by ion mobility mass spectrometry, differential scanning calorimetry, and X-ray crystallography

artículo científico publicado en 2017

The serum protein binding of pharmacologically active gallium(III) compounds assessed by hyphenated CE-MS techniques.

artículo científico publicado en 2009

Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity

artículo científico publicado en 2009

Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes

artículo científico publicado en 2010

Urinary Sex Steroid and Glucocorticoid Hormones Are Associated With Muscle Mass and Strength in Healthy Adults

artículo científico publicado en 2019

Lista de obras de Michael Groessl

A calibration framework for the determination of accurate collision cross sections of polyanions using polyoxometalate standards

A comprehensive urinary steroid analysis strategy using two-dimensional gas chromatography - time of flight mass spectrometry

A glucose derivative as natural alternative to the cyclohexane-1,2-diamine ligand in the anticancer drug oxaliplatin?

A novel cytotoxic cerium complex: aquatrichloridobis(1,10-phenanthroline)cerium(III) (KP776). Synthesis, characterization, behavior in H2O, binding towards biomolecules, and antiproliferative activity

A novel framework for molecular characterization of atmospherically relevant organic compounds based on collision cross section and mass-to-charge ratio

A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core

Anthracene-tethered ruthenium(II) arene complexes as tools to visualize the cellular localization of putative organometallic anticancer compounds

Anticancer metallodrug research analytically painting the “omics” picture—current developments and future trends ⬇️

Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs ⬇️

Bioanalytical and biophysical techniques for the elucidation of the mode of action of metal-based drugs

CZE-ICP-MS as a tool for studying the hydrolysis of ruthenium anticancer drug candidates and their reactivity towards the DNA model compound dGMP.

Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: a novel approach for the analysis of anticancer metallodrugs in human serum and plasma

Cellular uptake and subcellular distribution of ruthenium-based metallodrugs under clinical investigation versus cisplatin

Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets

Characterization of Two Novel Variants of the Steroidogenic Acute Regulatory Protein Identified in a Girl with Classic Lipoid Congenital Adrenal Hyperplasia

Collision cross sections of negative cluster ions of phosphoric acid in N2 determined by drift tube ion mobility and their use in travelling wave ion mobility

Combination of metallomics and proteomics to study the effects of the metallodrug RAPTA-T on human cancer cells

Comparison of UHPLC-ESI-MS and Hadamard transform atmospheric pressure ion mobility-ESI-MS for rapid profiling of isomeric flavonoids

Concentration and Chemical Stability of Commercially Available Insulins: A High-Resolution Mass Spectrometry Study

DOSY NMR, X-ray Structural and Ion-Mobility Mass Spectrometric Studies on Electron-Deficient and Electron-Rich M6L4 Coordination Cages

Elucidation of the interactions of an anticancer ruthenium complex in clinical trials with biomolecules utilizing capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry. Short communication

Greener synthesis of new ammonium ionic liquids and their potential as extracting agents

High resolution ion mobility-mass spectrometry for separation and identification of isomeric lipids

High-Resolution Ion Mobility Spectrometry for Rapid Cannabis Potency Testing.

Highly Oxygenated Multifunctional Compounds in α-Pinene Secondary Organic Aerosol.

How high-resolution techniques enable reliable steroid identification and quantification

In vitro anticancer activity and biologically relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands

Interactions of a novel ruthenium-based anticancer drug (KP1019 or FFC14a) with serum proteins--significance for the patient

Ion mobility spectrometry–mass spectrometry (IMS–MS) for on- and offline analysis of atmospheric gas and aerosol species

Ion mobility–mass spectrometry of supramolecular complexes and assemblies

KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients

Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity

Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules

Mass Spectrometric and Theoretical Study of Polyiodides: The Connection between Solid State, Solution, and Gas Phases

Metal-Based Inhibition of Poly(ADP-ribose) Polymerase − The Guardian Angel of DNA ⬇️

Multinuclear cytotoxic metallodrugs: physicochemical characterization and biological properties of novel heteronuclear gold-titanium complexes

Nanoscalic silver possesses broad-spectrum antimicrobial activities and exhibits fewer toxicological side effects than silver sulfadiazine

New Insights into the Chemistry of the Antineoplastic Lanthanum Complex Tris(1,10-phenanthroline)tris(thiocyanato-κN)lanthanum(III) (KP772) and Its Interaction with Biomolecules

Premature adrenarche in girls is characterized by enhanced 17,20-lyase and 17β-hydroxysteroid dehydrogenase activities

Profiling of the human monocytic cell secretome by quantitative label-free mass spectrometry identifies stimulus-specific cytokines and proinflammatory proteins

Proteins as possible targets for cytotoxic trans-platinum(II) complexes with aliphatic amine ligands: Further exceptions to the DNA paradigm

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts

Quantitative Fragmentation Model for Bottom-Up Shotgun Lipidomics

Rapid quantification of insulin degludec by immunopurification combined with liquid chromatography high-resolution mass spectrometry

Reactivity of anticancer metallodrugs with serum proteins: new insights from size exclusion chromatography-ICP-MS and ESI-MS

Response Profiling Using Shotgun Proteomics Enables Global Metallodrug Mechanisms of Action To Be Established.

Reversion of Structure-Activity Relationships of Antitumor Platinum Complexes by Acetoxime but Not Hydroxylamine Ligands

Revisiting Steroidogenic Pathways in the Human Placenta and Primary Human Trophoblast Cells

Ruthenium versus platinum: interactions of anticancer metallodrugs with duplex oligonucleotides characterised by electrospray ionisation mass spectrometry

Short-Term Fasting Attenuates Overall Steroid Hormone Biosynthesis in Healthy Young Women

Simultaneous endo and exo Complex Formation of Pyridine[4]arene Dimers with Neutral and Anionic Guests.

Steroid identification via deep learning retention time predictions and two-dimensional gas chromatography-high resolution mass spectrometry

Structure-activity relationships for NAMI-A-type complexes (HL)[trans-RuCl4L(S-dmso)ruthenate(III)] (L = imidazole, indazole, 1,2,4-triazole, 4-amino-1,2,4-triazole, and 1-methyl-1,2,4-triazole): aquation, redox properties, protein binding, and anti

Superchiral Pd3 L6 Coordination Complex and Its Reversible Structural Conversion into Pd3 L3 Cl6 Metallocycles.

Synthesis and characterization of a new class of anti-angiogenic agents based on ruthenium clusters

The first example of MEEKC-ICP-MS coupling and its application for the analysis of anticancer platinum complexes

The metalation of hen egg white lysozyme impacts protein stability as shown by ion mobility mass spectrometry, differential scanning calorimetry, and X-ray crystallography

The serum protein binding of pharmacologically active gallium(III) compounds assessed by hyphenated CE-MS techniques.

Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity

Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes

Urinary Sex Steroid and Glucocorticoid Hormones Are Associated With Muscle Mass and Strength in Healthy Adults