Lista de obras - Tomohiro Numata - Dominio Público Uruguay

"TRP inflammation" relationship in cardiovascular system

artículo científico publicado en 2016

A novel inhibitor of hypertonicity-induced cation channels in HeLa cells

scientific article published on 28 June 2007

Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure

artículo científico publicado en 2016

Acid-sensitive outwardly rectifying (ASOR) anion channels in human epithelial cells are highly sensitive to temperature and independent of ClC-3.

artículo científico publicado en 2013

Active Zone Protein Bassoon Co-Localizes with Presynaptic Calcium Channel, Modifies Channel Function, and Recovers from Aging Related Loss by Exercise ⬇️

artículo científico publicado el 6 de junio de 2012

Allosteric activation of membrane-bound glutamate receptors using coordination chemistry within living cells.

artículo científico publicado en 2016

Cellular mechanism for herbal medicine Junchoto to facilitate intestinal Cl-/water secretion that involves cAMP-dependent activation of CFTR.

artículo científico publicado en 2018

Characterization of single L-type Ca2+ channels in myocytes isolated from the cricket lateral oviduct.

artículo científico publicado en 2005

Characterization of stretch-activated calcium permeable cation channels in freshly isolated myocytes of the cricket (Gryllus bimaculatus) lateral oviduct

artículo científico publicado en 2005

Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS

artículo científico publicado en 2016

Compromised maturation of GABAergic inhibition underlies abnormal network activity in the hippocampus of epileptic Ca2+ channel mutant mice, tottering.

artículo científico publicado en 2014

Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation

artículo científico publicado en 2020

Different Contribution of Redox-Sensitive Transient Receptor Potential Channels to Acetaminophen-Induced Death of Human Hepatoma Cell Line.

artículo científico publicado en 2016

Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry

artículo científico publicado en 2016

Distinct Mechanism of Cysteine Oxidation-Dependent Activation and Cold Sensitization of Human Transient Receptor Potential Ankyrin 1 Channel by High and Low Oxaliplatin.

artículo científico publicado en 2017

Distinct contributions of LRRC8A and its paralogs to the VSOR anion channel from those of the ASOR anion channel

artículo científico publicado en 2016

Distinct pharmacological and molecular properties of the acid-sensitive outwardly rectifying (ASOR) anion channel from those of the volume-sensitive outwardly rectifying (VSOR) anion channel

artículo científico publicado en 2016

Expression of N-type calcium channels in human adrenocortical cells and their contribution to corticosteroid synthesis.

artículo científico publicado en 2010

Herbal components of Japanese Kampo medicines exert laxative actions in colonic epithelium cells via activation of BK and CFTR channels

artículo científico publicado en 2019

Hypertonicity-induced cation channels rescue cells from staurosporine-elicited apoptosis.

artículo científico publicado en 2008

Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models

artículo científico publicado en 2016

Integrative Approach with Electrophysiological and Theoretical Methods Reveals a New Role of S4 Positively Charged Residues in PKD2L1 Channel Voltage-Sensing.

artículo científico publicado en 2017

Involvements of the ABC protein ABCF2 and α‐actinin‐4 in regulation of cell volume and anion channels in human epithelial cells ⬇️

artículo científico publicado el 1 de octubre de 2012

Mutations in EFHC1 cause juvenile myoclonic epilepsy

artículo científico publicado en 2004

Novel HCN2 mutation contributes to febrile seizures by shifting the channel's kinetics in a temperature-dependent manner

artículo científico publicado en 2013

Optical control of neuronal firing via photoinduced electron transfer in donor-acceptor conjugates

scientific article published on 17 February 2016

Pathophysiology and puzzles of the volume-sensitive outwardly rectifying anion channel.

artículo científico publicado en 2009

Proton conductivity through the human TRPM7 channel and its molecular determinants

artículo científico publicado en 2008

Role of acid-sensitive outwardly rectifying anion channels in acidosis-induced cell death in human epithelial cells

scientific article published on 22 December 2006

Sensitization of H2O2-induced TRPM2 activation and subsequent interleukin-8 (CXCL8) production by intracellular Fe(2+) in human monocytic U937 cells

artículo científico publicado en 2015

Signalling events employed in the hypertonic activation of cation channels in HeLa cells

scientific article published on 01 January 2007

TRP channels as sensors of oxygen availability ⬇️

artículo científico publicado el 17 de febrero de 2013

TRPM1: a vertebrate TRP channel responsible for retinal ON bipolar function.

artículo científico publicado en 2010

TRPM2 channels in alveolar epithelial cells mediate bleomycin-induced lung inflammation

artículo científico publicado en 2015

TRPM7 channels mediate spontaneous Ca2+ fluctuations in growth plate chondrocytes that promote bone development

scientific article published on 09 April 2019

TRPM7 is a stretch- and swelling-activated cation channel involved in volume regulation in human epithelial cells.

artículo científico publicado en 2006

TRPM7 is involved in acid-induced necrotic cell death in a manner sensitive to progesterone in human cervical cancer cells

artículo científico publicado en 2019

Targeting TRPs in neurodegenerative disorders.

artículo científico publicado en 2013

Temperature sensitivity of acid-sensitive outwardly rectifying (ASOR) anion channels in cortical neurons is involved in hypothermic neuroprotection against acidotoxic necrosis

artículo científico publicado en 2014

The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death.

artículo científico publicado en 2012

The ΔC splice-variant of TRPM2 is the hypertonicity-induced cation channel in HeLa cells, and the ecto-enzyme CD38 mediates its activation

artículo científico publicado en 2012

Thermosensitive Ion Channel Activation in Single Neuronal Cells by Using Surface-Engineered Plasmonic Nanoparticles

artículo científico publicado en 2015

Transient receptor potential melastatin 2 protects mice against polymicrobial sepsis by enhancing bacterial clearance

artículo científico publicado en 2014

Transnitrosylation directs TRPA1 selectivity in N-nitrosamine activators

artículo científico publicado en 2013

Uncovering the arrhythmogenic potential of TRPM4 activation in atrial-derived HL-1 cells using novel recording and numerical approaches

artículo científico publicado en 2017

Utilization of Photoinduced Charge-Separated State of Donor–Acceptor-Linked Molecules for Regulation of Cell Membrane Potential and Ion Transport

artículo científico publicado en 2012

V₂ receptor-mediated autocrine role of somatodendritic release of AVP in rat vasopressin neurons under hypo-osmotic conditions

artículo científico publicado en 2011

Lista de obras de Tomohiro Numata

"TRP inflammation" relationship in cardiovascular system

A novel inhibitor of hypertonicity-induced cation channels in HeLa cells

Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure

Acid-sensitive outwardly rectifying (ASOR) anion channels in human epithelial cells are highly sensitive to temperature and independent of ClC-3.

Active Zone Protein Bassoon Co-Localizes with Presynaptic Calcium Channel, Modifies Channel Function, and Recovers from Aging Related Loss by Exercise ⬇️

Allosteric activation of membrane-bound glutamate receptors using coordination chemistry within living cells.

Cellular mechanism for herbal medicine Junchoto to facilitate intestinal Cl-/water secretion that involves cAMP-dependent activation of CFTR.

Characterization of single L-type Ca2+ channels in myocytes isolated from the cricket lateral oviduct.

Characterization of stretch-activated calcium permeable cation channels in freshly isolated myocytes of the cricket (Gryllus bimaculatus) lateral oviduct

Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS

Compromised maturation of GABAergic inhibition underlies abnormal network activity in the hippocampus of epileptic Ca2+ channel mutant mice, tottering.

Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation

Different Contribution of Redox-Sensitive Transient Receptor Potential Channels to Acetaminophen-Induced Death of Human Hepatoma Cell Line.

Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry

Distinct Mechanism of Cysteine Oxidation-Dependent Activation and Cold Sensitization of Human Transient Receptor Potential Ankyrin 1 Channel by High and Low Oxaliplatin.

Distinct contributions of LRRC8A and its paralogs to the VSOR anion channel from those of the ASOR anion channel

Distinct pharmacological and molecular properties of the acid-sensitive outwardly rectifying (ASOR) anion channel from those of the volume-sensitive outwardly rectifying (VSOR) anion channel

Expression of N-type calcium channels in human adrenocortical cells and their contribution to corticosteroid synthesis.

Herbal components of Japanese Kampo medicines exert laxative actions in colonic epithelium cells via activation of BK and CFTR channels

Hypertonicity-induced cation channels rescue cells from staurosporine-elicited apoptosis.

Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models

Integrative Approach with Electrophysiological and Theoretical Methods Reveals a New Role of S4 Positively Charged Residues in PKD2L1 Channel Voltage-Sensing.

Involvements of the ABC protein ABCF2 and α‐actinin‐4 in regulation of cell volume and anion channels in human epithelial cells ⬇️

Mutations in EFHC1 cause juvenile myoclonic epilepsy

Novel HCN2 mutation contributes to febrile seizures by shifting the channel's kinetics in a temperature-dependent manner

Optical control of neuronal firing via photoinduced electron transfer in donor-acceptor conjugates

Pathophysiology and puzzles of the volume-sensitive outwardly rectifying anion channel.

Proton conductivity through the human TRPM7 channel and its molecular determinants

Role of acid-sensitive outwardly rectifying anion channels in acidosis-induced cell death in human epithelial cells

Sensitization of H2O2-induced TRPM2 activation and subsequent interleukin-8 (CXCL8) production by intracellular Fe(2+) in human monocytic U937 cells

Signalling events employed in the hypertonic activation of cation channels in HeLa cells

TRP channels as sensors of oxygen availability ⬇️

TRPM1: a vertebrate TRP channel responsible for retinal ON bipolar function.

TRPM2 channels in alveolar epithelial cells mediate bleomycin-induced lung inflammation

TRPM7 channels mediate spontaneous Ca2+ fluctuations in growth plate chondrocytes that promote bone development

TRPM7 is a stretch- and swelling-activated cation channel involved in volume regulation in human epithelial cells.

TRPM7 is involved in acid-induced necrotic cell death in a manner sensitive to progesterone in human cervical cancer cells

Targeting TRPs in neurodegenerative disorders.

Temperature sensitivity of acid-sensitive outwardly rectifying (ASOR) anion channels in cortical neurons is involved in hypothermic neuroprotection against acidotoxic necrosis

The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death.

The ΔC splice-variant of TRPM2 is the hypertonicity-induced cation channel in HeLa cells, and the ecto-enzyme CD38 mediates its activation

Thermosensitive Ion Channel Activation in Single Neuronal Cells by Using Surface-Engineered Plasmonic Nanoparticles

Transient receptor potential melastatin 2 protects mice against polymicrobial sepsis by enhancing bacterial clearance

Transnitrosylation directs TRPA1 selectivity in N-nitrosamine activators

Uncovering the arrhythmogenic potential of TRPM4 activation in atrial-derived HL-1 cells using novel recording and numerical approaches

Utilization of Photoinduced Charge-Separated State of Donor–Acceptor-Linked Molecules for Regulation of Cell Membrane Potential and Ion Transport

V₂ receptor-mediated autocrine role of somatodendritic release of AVP in rat vasopressin neurons under hypo-osmotic conditions