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Lista de obras de Lars G Fritsche

A Case-Crossover Phenome-wide Association Study (PheWAS) for Understanding Post-COVID-19 Diagnosis Patterns

scholarly article

A Scalable Bayesian Method for Integrating Functional Information in Genome-wide Association Studies

artículo científico publicado en 2017

A Subgroup of Age-Related Macular Degeneration is Associated With Mono-Allelic Sequence Variants in theABCA4Gene ⬇️

artículo científico publicado el 30 de abril de 2012

A fast and accurate method for genome-wide scale phenome-wide G × E analysis and its application to UK biobank

journal article published in 2019

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

artículo científico publicado en 2015

A phenome-wide association study (PheWAS) of COVID-19 outcomes by race using the electronic health records data in Michigan Medicine

scientific article published on 01 July 2020

Age-of-onset information helps identify 76 genetic variants associated with allergic disease

scientific article published on 30 June 2020

Age-related macular degeneration and coronary heart disease: evaluation of genetic and environmental associations

artículo científico publicado en 2012

Age-related macular degeneration and functional promoter and coding variants of the apolipoprotein E gene

artículo científico publicado en 2009

Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA

artículo científico publicado en 2008

Age-related macular degeneration with discordant late stage phenotypes in monozygotic twins.

artículo científico publicado en 2011

Age-related macular degeneration: genetics and biology coming together

artículo científico publicado en 2014

An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)

artículo científico publicado en 2010

Assessment of the contribution of CFH and chromosome 10q26 AMD susceptibility loci in a Russian population isolate.

artículo científico publicado en 2006

Association of Genetic Variants With Response to Anti-Vascular Endothelial Growth Factor Therapy in Age-Related Macular Degeneration

artículo científico publicado en 2018

Association of Polygenic Risk Scores for Multiple Cancers in a Phenome-wide Study: Results from The Michigan Genomics Initiative

artículo científico publicado en 2018

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

artículo científico publicado en 2019

Author Correction: Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration

scientific article published on 01 June 2019

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

scientific article published on 30 July 2018

Bivariate Analysis of Age-Related Macular Degeneration Progression Using Genetic Risk Scores

artículo científico publicado en 2017

CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD

artículo científico publicado en 2009

COVID-19 Outcomes by Cancer Status, Site, Treatment, and Vaccination

COVID-19 outcomes by cancer status, type, treatment, and vaccination

COVID-19 outcomes, risk factors and associations by race: a comprehensive analysis using electronic health records data in Michigan Medicine

scientific article published on 18 June 2020

CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors

artículo científico publicado en 2010

Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks

artículo científico publicado en 2020

Case-control genetic association study of fibulin-6 (FBLN6 or HMCN1) variants in age-related macular degeneration (AMD)

artículo científico publicado en 2007

Characterizing and Predicting Post-Acute Sequelae of SARS CoV-2 infection (PASC) in a Large Academic Medical Center in the US

Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract

scientific article published on 11 December 2020

Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype

artículo científico publicado en 2012

Correction: Developing and validating a multivariable prediction model which predicts progression of intermediate to late age-related macular degeneration—the PINNACLE trial protocol

artículo científico publicado en 2022

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

artículo científico publicado en 2018

Estimation of DNA contamination and its sources in genotyped samples

scientific article published on 26 August 2019

Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study

scientific article published on 31 January 2019

Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies

artículo científico publicado en 2011

ExPRSweb - An Online Repository with Polygenic Risk Scores for Common Health-related Exposures

Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.

artículo científico publicado en 2017

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

Expanding the spectrum of PTH1R mutations in patients with primary failure of tooth eruption ⬇️

artículo científico publicado el 15 de junio de 2013

Exploring and visualizing large-scale genetic associations by using PheWeb

artículo científico publicado en 2020

Exploring various polygenic risk scores for skin cancer in the phenomes of the Michigan genomics initiative and the UK Biobank with a visual catalog: PRSWeb

artículo científico publicado en 2019

First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes

artículo científico publicado en 2018

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

artículo científico publicado en 2020

Genes for Good: Engaging the Public in Genetics Research via Social Media

artículo científico publicado en 2019

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

artículo científico publicado en 2018

Genome-wide Analysis of Disease Progression in Age-related Macular Degeneration

artículo científico publicado en 2018

Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development

artículo científico publicado en 2017

Genome-wide analysis yields new loci associating with aortic valve stenosis

artículo científico publicado en 2018

Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility

artículo científico publicado en 2020

Genotype imputation in genome-wide association studies

artículo científico

Geographic distribution of rare variants associated with age-related macular degeneration

artículo científico publicado en 2018

Global Prevalence of Post-Acute Sequelae of COVID-19 (PASC) or Long COVID: A Meta-Analysis and Systematic Review

HDL-cholesterol levels and risk of age-related macular degeneration: a multiethnic genetic study using Mendelian randomization

artículo científico publicado en 2017

Heritability of the Fibromyalgia Phenotype Varies by Age

scientific article published on 17 November 2019

Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk

artículo científico publicado en 2005

Improving power of association tests using multiple sets of imputed genotypes from distributed reference panels.

artículo científico publicado en 2017

In Silico Functional Meta-Analysis of 5,962 ABCA4 Variants in 3,928 Retinal Dystrophy Cases

artículo científico publicado en 2017

LabWAS: Novel findings and study design recommendations from a meta-analysis of clinical labs in two independent biobanks

artículo científico publicado en 2020

MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk

artículo científico publicado en 2020

Meta-MultiSKAT: Multiple phenotype meta-analysis for region-based association test

scientific article published on 21 August 2019

Modelling the genetic risk in age-related macular degeneration.

artículo científico publicado en 2012

Multicenter cohort association study of SLC2A1 single nucleotide polymorphisms and age-related macular degeneration

artículo científico publicado en 2012

No clinically significant association between CFH and ARMS2 genotypes and response to nutritional supplements: AREDS report number 38

artículo científico publicado en 2014

Novel Common Genetic Susceptibility Loci for Colorectal Cancer

artículo científico publicado en 2019

On cross-ancestry cancer polygenic risk scores

Patterns of repeated diagnostic testing for COVID19 in relation to patient characteristics and outcomes

artículo científico publicado en 2020

Prediction of Ankylosing Spondylitis in the HUNT Study by a Genetic Risk Score Combining 110 Single-nucleotide Polymorphisms of Genome-wide Significance

artículo científico publicado en 2019

Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve

artículo científico publicado en 2017

Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration

scientific article published on 11 February 2019

Risk- and non-risk-associated variants at the 10q26 AMD locus influence ARMS2 mRNA expression but exclude pathogenic effects due to protein deficiency.

artículo científico publicado en 2011

Robust meta-analysis of biobank-based genome-wide association studies with unbalanced binary phenotypes

scientific article published on 22 February 2019

Scalable generalized linear mixed model for region-based association tests in large biobanks and cohorts

scientific article published on 18 May 2020

Seven new loci associated with age-related macular degeneration

artículo científico publicado en 2013

Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis

scientific article published on 23 April 2019

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology

artículo científico publicado en 2017

Systemic complement activation in age-related macular degeneration

artículo científico publicado en 2008

The emerging landscape of health research based on biobanks linked to electronic health records: existing resources, statistical challenges, and potential opportunities

artículo científico publicado en 2019

UK Biobank Whole-Exome Sequence Binary Phenome Analysis with Robust Region-Based Rare-Variant Test

scientific article published on 19 December 2019

Understanding the patterns of repeated testing for COVID-19: Association with patient characteristics and outcomes

scientific article published on 29 July 2020

Validating Online Measures of Cognitive Ability in Genes for Good, a Genetic Study of Health and Behavior

artículo científico publicado en 2017

Variation in Serum PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9), Cardiovascular Disease Risk, and an Investigation of Potential Unanticipated Effects of PCSK9 Inhibition

artículo científico publicado en 2019

Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people

artículo científico publicado en 2011

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