Lista de obras - Michael G Schlossmacher - Dominio Público Uruguay

A First Tetraplex Assay for the Simultaneous Quantification of Total α-Synuclein, Tau, β-Amyloid42 and DJ-1 in Human Cerebrospinal Fluid

artículo científico publicado en 2016

Acid β-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α-synuclein processing.

artículo científico publicado en 2011

Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites

artículo científico publicado en 2021

Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.

artículo científico publicado en 2007

Alpha-synuclein in the appendiceal mucosa of neurologically intact subjects.

artículo científico publicado en 2013

Aβ oligomers induce pathophysiological mGluR5 signaling in Alzheimer's disease model mice in a sex-selective manner

artículo científico publicado en 2020

Biological confounders for the values of cerebrospinal fluid proteins in Parkinson's disease and related disorders

artículo científico

Biomarker research in Parkinson's disease: objective measures needed for patient stratification in future cause-directed trials.

artículo científico publicado en 2010

CNS expression of glucocerebrosidase corrects alpha-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy

artículo científico publicado en 2011

CSF synuclein: adding to the biomarker footprint of dementia with Lewy bodies

artículo científico publicado en 2010

Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 27-2004. A 79-year-old woman with disturbances in gait, cognition, and autonomic function

scientific article published on 01 August 2004

Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo.

artículo científico publicado en 2009

Considerations regarding the etiology and future treatment of autosomal recessive versus idiopathic Parkinson disease.

artículo científico

Conversations With Dr. Oleh Hornykiewicz, Founding Father of the Dopamine Era in Parkinson's: How Do You Wish to Be Remembered?

scientific article published on 14 October 2020

Deciphering the role of heterozygous mutations in genes associated with parkinsonism

artículo científico publicado en 2007

Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease

artículo científico publicado en 2006

Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease

scientific article published on 01 March 2006

Detection of soluble forms of the beta-amyloid precursor protein in human plasma

artículo científico publicado en 1990

Differential mobility spectrometry as an orthogonal separation to LC-ESI-MS/MS for quantification of isomeric cerebrosides in plasma and cerebrospinal fluid

article

Dimerization of Parkinson's disease-causing DJ-1 and formation of high molecular weight complexes in human brain

artículo científico publicado en 2004

Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

artículo científico publicado en 2008

Dopamine covalently modifies and functionally inactivates parkin

artículo científico publicado en 2005

Expansion of the Parkinson disease-associated SNCA-Rep1 allele upregulates human alpha-synuclein in transgenic mouse brain.

artículo científico publicado en 2009

Fluid biomarkers in multiple system atrophy: A review of the MSA Biomarker Initiative.

artículo científico

GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein

artículo científico publicado en 2008

Hashimoto's encephalopathy mimicking Creutzfeldt-Jakob disease: brain biopsy findings.

artículo científico publicado en 2002

Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects

artículo científico publicado en 2017

Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains

artículo científico publicado en 2009

K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo.

artículo científico publicado en 2016

LRRK2 and Nod2 promote lysozyme sorting in Paneth cells.

artículo científico publicado en 2015

Lrrk2 alleles modulate inflammation during microbial infection of mice in a sex-dependent manner

scientific article published on 01 September 2019

Modelling idiopathic Parkinson disease as a complex illness can inform incidence rate in healthy adults: the PREDIGT score

artículo científico publicado en 2016

Molecular markers of early Parkinson's disease based on gene expression in blood

artículo científico publicado en 2007

Multiple system atrophy: a primary oligodendrogliopathy.

artículo científico publicado en 2008

Mutant GBA1 expression and synucleinopathy risk: first insights from cellular and mouse models.

artículo científico

Nonmotor and diagnostic findings in subjects with de novo Parkinson disease of the DeNoPa cohort

artículo científico publicado en 2013

Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies

artículo científico publicado en 2002

Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1

artículo científico publicado en 2013

Parkinson disease, 10 years after its genetic revolution: multiple clues to a complex disorder

artículo científico publicado en 2007

Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures

artículo científico publicado en 2011

Parkinson's disease: assays for the ubiquitin ligase activity of neural Parkin

artículo científico publicado en 2005

Protective effect of vagotomy suggests source organ for Parkinson disease

artículo científico publicado en 2015

Quantification of α-synuclein in cerebrospinal fluid as a biomarker candidate: review of the literature and considerations for future studies

artículo científico publicado en 2010

RING finger 1 mutations in Parkin produce altered localization of the protein

artículo científico publicado en 2003

Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting.

artículo científico publicado en 2017

Respiratory infection of mice with mammalian reoviruses causes systemic infection with age and strain dependent pneumonia and encephalitis.

artículo científico publicado en 2013

Seizures after epidural blood patch

artículo científico publicado en 2003

Serum heart-type fatty acid-binding protein and cerebrospinal fluid tau: marker candidates for dementia with Lewy bodies

artículo científico publicado en 2007

Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition

artículo científico publicado en 2005

Total CSF α-synuclein is lower in de novo Parkinson patients than in healthy subjects

artículo científico publicado en 2012

Towards translational therapies for multiple system atrophy

artículo científico publicado en 2014

Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study

artículo científico publicado en 2013

Vertebral artery dissection with a normal-appearing lumen at multisection CT angiography: the importance of identifying wall hematoma.

artículo científico publicado en 2009

beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.

artículo científico publicado en 1993

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study

artículo científico publicado en 2011

α-Synuclein in human cerebrospinal fluid is principally derived from neurons of the central nervous system

artículo científico publicado en 2012

Lista de obras de Michael G Schlossmacher

A First Tetraplex Assay for the Simultaneous Quantification of Total α-Synuclein, Tau, β-Amyloid42 and DJ-1 in Human Cerebrospinal Fluid

Acid β-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α-synuclein processing.

Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites

Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.

Alpha-synuclein in the appendiceal mucosa of neurologically intact subjects.

Aβ oligomers induce pathophysiological mGluR5 signaling in Alzheimer's disease model mice in a sex-selective manner

Biological confounders for the values of cerebrospinal fluid proteins in Parkinson's disease and related disorders

Biomarker research in Parkinson's disease: objective measures needed for patient stratification in future cause-directed trials.

CNS expression of glucocerebrosidase corrects alpha-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy

CSF synuclein: adding to the biomarker footprint of dementia with Lewy bodies

Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 27-2004. A 79-year-old woman with disturbances in gait, cognition, and autonomic function

Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo.

Considerations regarding the etiology and future treatment of autosomal recessive versus idiopathic Parkinson disease.

Conversations With Dr. Oleh Hornykiewicz, Founding Father of the Dopamine Era in Parkinson's: How Do You Wish to Be Remembered?

Deciphering the role of heterozygous mutations in genes associated with parkinsonism

Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease

Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease

Detection of soluble forms of the beta-amyloid precursor protein in human plasma

Differential mobility spectrometry as an orthogonal separation to LC-ESI-MS/MS for quantification of isomeric cerebrosides in plasma and cerebrospinal fluid

Dimerization of Parkinson's disease-causing DJ-1 and formation of high molecular weight complexes in human brain

Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

Dopamine covalently modifies and functionally inactivates parkin

Expansion of the Parkinson disease-associated SNCA-Rep1 allele upregulates human alpha-synuclein in transgenic mouse brain.

Fluid biomarkers in multiple system atrophy: A review of the MSA Biomarker Initiative.

GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein

Hashimoto's encephalopathy mimicking Creutzfeldt-Jakob disease: brain biopsy findings.

Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects

Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains

K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo.

LRRK2 and Nod2 promote lysozyme sorting in Paneth cells.

Lrrk2 alleles modulate inflammation during microbial infection of mice in a sex-dependent manner

Modelling idiopathic Parkinson disease as a complex illness can inform incidence rate in healthy adults: the PREDIGT score

Molecular markers of early Parkinson's disease based on gene expression in blood

Multiple system atrophy: a primary oligodendrogliopathy.

Mutant GBA1 expression and synucleinopathy risk: first insights from cellular and mouse models.

Nonmotor and diagnostic findings in subjects with de novo Parkinson disease of the DeNoPa cohort

Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies

Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1

Parkinson disease, 10 years after its genetic revolution: multiple clues to a complex disorder

Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures

Parkinson's disease: assays for the ubiquitin ligase activity of neural Parkin

Protective effect of vagotomy suggests source organ for Parkinson disease

Quantification of α-synuclein in cerebrospinal fluid as a biomarker candidate: review of the literature and considerations for future studies

RING finger 1 mutations in Parkin produce altered localization of the protein

Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting.

Respiratory infection of mice with mammalian reoviruses causes systemic infection with age and strain dependent pneumonia and encephalitis.

Seizures after epidural blood patch

Serum heart-type fatty acid-binding protein and cerebrospinal fluid tau: marker candidates for dementia with Lewy bodies

Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition

Total CSF α-synuclein is lower in de novo Parkinson patients than in healthy subjects

Towards translational therapies for multiple system atrophy

Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study

Vertebral artery dissection with a normal-appearing lumen at multisection CT angiography: the importance of identifying wall hematoma.

beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study

α-Synuclein in human cerebrospinal fluid is principally derived from neurons of the central nervous system