Lista de obras - Hatem Zayed - Dominio Público Uruguay

A Potential Link Between Oxidative Stress and Endothelial-to-Mesenchymal Transition in Systemic Sclerosis

artículo científico publicado en 2018

A comparative computational approach toward pharmacological chaperones (NN-DNJ and ambroxol) on N370S and L444P mutations causing Gaucher's disease

scientific article published on 01 December 2018

A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation causing breast cancer

scientific article published on 21 October 2019

A computational method to characterize the missense mutations in the catalytic domain of GAA protein causing Pompe disease

scholarly article by D Thirumal Kumar published in October 2018

A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase

artículo científico publicado en 2019

A maternally inherited chromosome 18q22.1 deletion in a male with late-presenting diaphragmatic hernia and microphthalmia-evaluation of DSEL as a candidate gene for the diaphragmatic defect

artículo científico publicado en 2010

A profound computational study to prioritize the disease-causing mutations in PRPS1 gene

artículo científico publicado en 2017

Accredited genetic testing in the Arab Gulf region: reinventing the wheel

An Arab Registry for Type 1 Diabetes: Global Benefits for Type 1 Diabetes Patients

artículo científico publicado en 2016

An extensive computational approach to analyze and characterize the functional mutations in the galactose-1-phosphate uridyl transferase (GALT) protein responsible for classical galactosemia

scientific article published on 13 December 2019

An integrative bioinformatics pipeline to demonstrate the alteration of the interaction between the ALDH2*2 allele with NAD+ and Disulfiram

artículo científico publicado en 2019

Anaphylaxis triggers in a large tertiary care hospital in Qatar: a retrospective study

artículo científico publicado en 2018

Association between Soft Drink Consumption and Aggressive Behaviour among a Quarter Million Adolescents from 64 Countries Based on the Global School-Based Student Health Survey (GSHS)

artículo científico publicado en 2020

Association of Genetic Variants with Colorectal Cancer in the Extended MENA Region: A Systematic Review

artículo científico publicado en 2020

Bioinformatics classification of mutations in patients with Mucopolysaccharidosis IIIA

scientific article published on 05 August 2019

Breast cancer in the GCC countries: A focus on BRCA1/2 and non-BRCA1/2 genes

CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion

artículo científico publicado en 2017

CD44 mediates stem cell mobilization to damaged lung via its novel transcriptional targets, Cortactin and Survivin

artículo científico publicado en 2020

Canavan disease: an Arab scenario

artículo científico publicado en 2015

Clinical Exome Sequencing unravels new disease-causing mutations in the myeloproliferative neoplasms: A pilot study in patients from the state of Qatar

artículo científico publicado en 2018

Clinical, biochemical, neuroradiological and molecular characterization of Egyptian patients with glutaric acidemia type 1

scientific article published on 06 May 2019

Comparative computational assessment of the pathogenicity of mutations in the Aspartoacylase enzyme

artículo científico publicado en 2017

Comprehensive in silico screening and molecular dynamics studies of missense mutations in Sjogren-Larsson syndrome associated with the ALDH3A2 gene

artículo científico publicado en 2020

Computational and modeling approaches to understand the impact of the Fabry's disease causing mutation (D92Y) on the interaction with pharmacological chaperone 1-deoxygalactonojirimycin (DGJ)

scientific article published on 18 December 2018

Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2

Computational insights of K1444N substitution in GAP-related domain of NF1 gene associated with neurofibromatosis type 1 disease: a molecular modeling and dynamics approach

article

Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder - Blau syndrome

artículo científico publicado en 2020

Computational modelling approaches as a potential platform to understand the molecular genetics association between Parkinson’s and Gaucher diseases

article

Congenital diaphragmatic hernia and microtia in a newborn with mycophenolate mofetil (MMF) exposure: phenocopy for Fryns syndrome or broad spectrum of teratogenic effects?

Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery

artículo científico publicado en 2007

Corrigendum: Genetic Epidemiology of Glucose-6-Phosphate Dehydrogenase Deficiency in the Arab World

artículo científico publicado en 2017

Deciphering the Role of Filamin B Calponin-Homology Domain in Causing the Larsen Syndrome, Boomerang Dysplasia, and Atelosteogenesis Type I Spectrum Disorders via a Computational Approach

scientific article published on 26 November 2020

Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach

artículo científico publicado en 2017

Development of hyperactive sleeping beauty transposon vectors by mutational analysis

artículo científico publicado en 2004

Differences in the neovascular potential of thymus versus subcutaneous adipose-derived stem cells from patients with myocardial ischaemia.

artículo científico publicado en 2017

Durable immunity to oncogenic human papillomaviruses elicited by adjuvanted recombinant Adeno-associated virus-like particle immunogen displaying L2 17-36 epitopes

artículo científico publicado en 2015

Elucidating the role of interacting residues of the MSH2-MSH6 complex in DNA repair mechanism: A computational approach

artículo científico publicado en 2019

Enhanced Identification of Transcriptional Enhancers Provides Mechanistic Insights into Diseases

artículo científico publicado en 2016

Epidemiology of diabetic ketoacidosis in Arab patients with type 1 diabetes: a systematic review

artículo científico publicado en 2016

Genetic Epidemiology of Glucose-6-Dehydrogenase Deficiency in the Arab World

artículo científico publicado en 2016

Genetic Epidemiology of Hearing Loss in the 22 Arab Countries: A Systematic Review

artículo científico publicado en 2020

Genetic Epidemiology of Type 1 Diabetes in the 22 Arab Countries

artículo científico publicado en 2016

Genetic epidemiology of beta-thalassemia in the Maldives: 23 years of a beta-thalassemia screening program

artículo científico publicado en 2020

Genetic epidemiology of ovarian cancer in the 22 Arab countries: A systematic review

article

Genetic polymorphisms associated with type 2 diabetes in the Arab world: A systematic review and meta-analysis

scientific article published on 04 April 2019

Genotype-phenotype correlation in 18 Egyptian patients with glutaric acidemia type I.

artículo científico publicado en 2017

Genotype-phenotype correlation in patients with isovaleric acidaemia: comparative structural modelling and computational analysis of novel variants

artículo científico

Identification of potential inhibitors against pathogenic missense mutations of PMM2 using a structure-based virtual screening approach

artículo científico publicado en 2020

Immunogenetics of Celiac Disease: A Focus on Arab Countries

artículo científico publicado en 2020

Impact of missense mutations in survival motor neuron protein (SMN1) leading to Spinal Muscular Atrophy (SMA): A computational approach

Implication of salt stress induces changes in pigment production, antioxidant enzyme activity, and qRT-PCR expression of genes involved in the biosynthetic pathway of Bixa orellana L

scientific article published on 29 January 2019

In silico and in vivo models for Qatari-Specific classical homocystinuria as basis for development of novel therapies

article

In vitro functional correction of the mutation responsible for murine severe combined immune deficiency by small fragment homologous replacement

artículo científico publicado en 2006

Inositol 1,4,5-Trisphosphate Receptors in Hypertension

artículo científico publicado en 2018

Integrative Bioinformatics Approaches to Map Potential Novel Genes and Pathways Involved in Ovarian Cancer

artículo científico publicado en 2019

Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia

artículo científico publicado en 2020

Involvement of Essential Signaling Cascades and Analysis of Gene Networks in Diabesity

artículo científico publicado en 2020

Krabbe Disease in the Arab World

artículo científico publicado en 2015

Molecular dynamics simulations to decipher the structural and functional consequences of pathogenic missense mutations in the galactosylceramidase (GALC) protein causing Krabbe's disease

scientific article published on 31 March 2020

Molecular dynamics-based analyses of the structural instability and secondary structure of the fibrinogen gamma chain protein with the D356V mutation

artículo científico publicado en 2016

Molecular insights of the G2019S substitution in LRRK2 kinase domain associated with Parkinson's disease: A molecular dynamics simulation approach

artículo científico publicado en 2019

Myocardial Ischemic Subject's Thymus Fat: A Novel Source of Multipotent Stromal Cells

artículo científico publicado en 2015

Neuropathy of type 1 diabetes in the Arab world: A systematic review and meta-analysis

artículo científico publicado en 2017

Novel CD44-downstream signaling pathways mediating breast tumor invasion

scholarly article by Allal Ouhtit published in October 2018

Novel Comprehensive Bioinformatics Approaches to Determine the Molecular Genetic Susceptibility Profile of Moderate and Severe Asthma

artículo científico publicado en 2020

Novel mutation in an Egyptian patient with infantile Canavan disease

artículo científico publicado en 2015

Potential routes of spread of Zika virus to the Middle East, North Africa and Asia: action must be taken

article

Prevalence of nephropathy in type 1 diabetes in the Arab world: A systematic review and meta-analysis

scientific article published on 08 June 2018

Propionic acidemia in the Arab World

artículo científico

Protective Effect of Cyclically Pressurized Solid–Liquid Extraction Polyphenols from Cagnulari Grape Pomace on Oxidative Endothelial Cell Death

artículo científico publicado en 2018

RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR.

artículo científico publicado en 2016

Rapid generation of stable cell lines expressing high levels of erythropoietin, factor VIII, and an antihuman CD20 antibody using lentiviral vectors

artículo científico publicado en 2013

Retinopathy of Type 1 Diabetes in Arab Countries: Systematic Review and Meta-Analysis

artículo científico publicado en 2018

Reverse Zoonotic Transmission of SARS-CoV-2 and Monkeypox Virus: A Comprehensive Review

artículo científico publicado en 2024

Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance

scientific article published on 12 March 2020

Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling

artículo científico publicado en 2019

Sanguinarine Induces Apoptosis in Papillary Thyroid Cancer Cells via Generation of Reactive Oxygen Species

artículo científico publicado en 2020

Severe neurological manifestations in an Egyptian patient with a novel frameshift mutation in the Glutaryl-CoA dehydrogenase gene

artículo científico publicado en 2016

Spectrum of mutations of cystic fibrosis in the 22 Arab countries: A systematic review

artículo científico publicado en 2018

Spectrum of mutations of familial hypercholesterolemia in the 22 Arab countries

article published in 2018

Structural Analysis of G1691S Variant in the Human Filamin B Gene Responsible for Larsen Syndrome: A Comparative Computational Approach.

artículo científico publicado en 2017

Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope

artículo científico publicado en 2017

Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2

scientific article published on 12 June 2018

Structural modeling of p.V31F variant in the aspartoacylase gene

artículo científico publicado en 2016

Substitution impact of highly conserved arginine residue at position 75 in GJB1 gene in association with X-linked Charcot-Marie-tooth disease: A computational study

artículo científico publicado en 2017

The Arab genome: Health and wealth

artículo científico publicado en 2016

The DNA-bending protein HMGB1 is a cellular cofactor of Sleeping Beauty transposition

artículo científico publicado en 2003

The Qatar genome project: translation of whole-genome sequencing into clinical practice

artículo científico publicado en 2016

The Role of Extracellular Vesicles as Modulators of the Tumor Microenvironment, Metastasis and Drug Resistance in Colorectal Cancer

artículo científico publicado en 2019

The transcriptomic profiling of COVID-19 compared to SARS, MERS, Ebola, and H1N1

artículo científico publicado en 2020

The transcriptomic profiling of SARS-CoV-2 compared to SARS, MERS, EBOV, and H1N1

scientific article published on 10 December 2020

Two patients with Canavan disease and structural modeling of a novel mutation

artículo científico publicado en 2016

Understanding Gene Expression and Transcriptome Profiling of COVID-19: An Initiative Towards the Mapping of Protective Immunity Genes Against SARS-CoV-2 Infection

artículo científico publicado en 2021

Understanding the structure-function relationship of HPRT1 missense mutations in association with Lesch-Nyhan disease and HPRT1-related gout by in silico mutational analysis

artículo científico publicado en 2019

Whole-Genome Sequencing of 100 Genomes Identifies a Distinctive Genetic Susceptibility Profile of Qatari Patients with Hypertension

artículo científico publicado en 2022

miR-20b, miR-296, and Let-7f Expression in Human Adipose Tissue is Related to Obesity and Type 2 Diabetes

scientific article published on 30 December 2018

miR-21 mimic blocks obesity in mice: A novel therapeutic option

artículo científico publicado en 2021

Lista de obras de Hatem Zayed

A Potential Link Between Oxidative Stress and Endothelial-to-Mesenchymal Transition in Systemic Sclerosis

A comparative computational approach toward pharmacological chaperones (NN-DNJ and ambroxol) on N370S and L444P mutations causing Gaucher's disease

A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation causing breast cancer

A computational method to characterize the missense mutations in the catalytic domain of GAA protein causing Pompe disease

A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase

A maternally inherited chromosome 18q22.1 deletion in a male with late-presenting diaphragmatic hernia and microphthalmia-evaluation of DSEL as a candidate gene for the diaphragmatic defect

A profound computational study to prioritize the disease-causing mutations in PRPS1 gene

Accredited genetic testing in the Arab Gulf region: reinventing the wheel

An Arab Registry for Type 1 Diabetes: Global Benefits for Type 1 Diabetes Patients

An extensive computational approach to analyze and characterize the functional mutations in the galactose-1-phosphate uridyl transferase (GALT) protein responsible for classical galactosemia

An integrative bioinformatics pipeline to demonstrate the alteration of the interaction between the ALDH2*2 allele with NAD+ and Disulfiram

Anaphylaxis triggers in a large tertiary care hospital in Qatar: a retrospective study

Association between Soft Drink Consumption and Aggressive Behaviour among a Quarter Million Adolescents from 64 Countries Based on the Global School-Based Student Health Survey (GSHS)

Association of Genetic Variants with Colorectal Cancer in the Extended MENA Region: A Systematic Review

Bioinformatics classification of mutations in patients with Mucopolysaccharidosis IIIA

Breast cancer in the GCC countries: A focus on BRCA1/2 and non-BRCA1/2 genes

CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion

CD44 mediates stem cell mobilization to damaged lung via its novel transcriptional targets, Cortactin and Survivin

Canavan disease: an Arab scenario

Clinical Exome Sequencing unravels new disease-causing mutations in the myeloproliferative neoplasms: A pilot study in patients from the state of Qatar

Clinical, biochemical, neuroradiological and molecular characterization of Egyptian patients with glutaric acidemia type 1

Comparative computational assessment of the pathogenicity of mutations in the Aspartoacylase enzyme

Comprehensive in silico screening and molecular dynamics studies of missense mutations in Sjogren-Larsson syndrome associated with the ALDH3A2 gene

Computational and modeling approaches to understand the impact of the Fabry's disease causing mutation (D92Y) on the interaction with pharmacological chaperone 1-deoxygalactonojirimycin (DGJ)

Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2

Computational insights of K1444N substitution in GAP-related domain of NF1 gene associated with neurofibromatosis type 1 disease: a molecular modeling and dynamics approach

Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder - Blau syndrome

Computational modelling approaches as a potential platform to understand the molecular genetics association between Parkinson’s and Gaucher diseases

Congenital diaphragmatic hernia and microtia in a newborn with mycophenolate mofetil (MMF) exposure: phenocopy for Fryns syndrome or broad spectrum of teratogenic effects?

Correction of DNA protein kinase deficiency by spliceosome-mediated RNA trans-splicing and sleeping beauty transposon delivery

Corrigendum: Genetic Epidemiology of Glucose-6-Phosphate Dehydrogenase Deficiency in the Arab World

Deciphering the Role of Filamin B Calponin-Homology Domain in Causing the Larsen Syndrome, Boomerang Dysplasia, and Atelosteogenesis Type I Spectrum Disorders via a Computational Approach

Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach

Development of hyperactive sleeping beauty transposon vectors by mutational analysis

Differences in the neovascular potential of thymus versus subcutaneous adipose-derived stem cells from patients with myocardial ischaemia.

Durable immunity to oncogenic human papillomaviruses elicited by adjuvanted recombinant Adeno-associated virus-like particle immunogen displaying L2 17-36 epitopes

Elucidating the role of interacting residues of the MSH2-MSH6 complex in DNA repair mechanism: A computational approach

Enhanced Identification of Transcriptional Enhancers Provides Mechanistic Insights into Diseases

Epidemiology of diabetic ketoacidosis in Arab patients with type 1 diabetes: a systematic review

Genetic Epidemiology of Glucose-6-Dehydrogenase Deficiency in the Arab World

Genetic Epidemiology of Hearing Loss in the 22 Arab Countries: A Systematic Review

Genetic Epidemiology of Type 1 Diabetes in the 22 Arab Countries

Genetic epidemiology of beta-thalassemia in the Maldives: 23 years of a beta-thalassemia screening program

Genetic epidemiology of ovarian cancer in the 22 Arab countries: A systematic review

Genetic polymorphisms associated with type 2 diabetes in the Arab world: A systematic review and meta-analysis

Genotype-phenotype correlation in 18 Egyptian patients with glutaric acidemia type I.

Genotype-phenotype correlation in patients with isovaleric acidaemia: comparative structural modelling and computational analysis of novel variants

Identification of potential inhibitors against pathogenic missense mutations of PMM2 using a structure-based virtual screening approach

Immunogenetics of Celiac Disease: A Focus on Arab Countries

Impact of missense mutations in survival motor neuron protein (SMN1) leading to Spinal Muscular Atrophy (SMA): A computational approach

Implication of salt stress induces changes in pigment production, antioxidant enzyme activity, and qRT-PCR expression of genes involved in the biosynthetic pathway of Bixa orellana L

In silico and in vivo models for Qatari-Specific classical homocystinuria as basis for development of novel therapies

In vitro functional correction of the mutation responsible for murine severe combined immune deficiency by small fragment homologous replacement

Inositol 1,4,5-Trisphosphate Receptors in Hypertension

Integrative Bioinformatics Approaches to Map Potential Novel Genes and Pathways Involved in Ovarian Cancer

Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia

Involvement of Essential Signaling Cascades and Analysis of Gene Networks in Diabesity

Krabbe Disease in the Arab World

Molecular dynamics simulations to decipher the structural and functional consequences of pathogenic missense mutations in the galactosylceramidase (GALC) protein causing Krabbe's disease

Molecular dynamics-based analyses of the structural instability and secondary structure of the fibrinogen gamma chain protein with the D356V mutation

Molecular insights of the G2019S substitution in LRRK2 kinase domain associated with Parkinson's disease: A molecular dynamics simulation approach

Myocardial Ischemic Subject's Thymus Fat: A Novel Source of Multipotent Stromal Cells

Neuropathy of type 1 diabetes in the Arab world: A systematic review and meta-analysis

Novel CD44-downstream signaling pathways mediating breast tumor invasion

Novel Comprehensive Bioinformatics Approaches to Determine the Molecular Genetic Susceptibility Profile of Moderate and Severe Asthma

Novel mutation in an Egyptian patient with infantile Canavan disease

Potential routes of spread of Zika virus to the Middle East, North Africa and Asia: action must be taken

Prevalence of nephropathy in type 1 diabetes in the Arab world: A systematic review and meta-analysis

Propionic acidemia in the Arab World

Protective Effect of Cyclically Pressurized Solid–Liquid Extraction Polyphenols from Cagnulari Grape Pomace on Oxidative Endothelial Cell Death

RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR.

Rapid generation of stable cell lines expressing high levels of erythropoietin, factor VIII, and an antihuman CD20 antibody using lentiviral vectors

Retinopathy of Type 1 Diabetes in Arab Countries: Systematic Review and Meta-Analysis

Reverse Zoonotic Transmission of SARS-CoV-2 and Monkeypox Virus: A Comprehensive Review

Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance

Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling

Sanguinarine Induces Apoptosis in Papillary Thyroid Cancer Cells via Generation of Reactive Oxygen Species

Severe neurological manifestations in an Egyptian patient with a novel frameshift mutation in the Glutaryl-CoA dehydrogenase gene

Spectrum of mutations of cystic fibrosis in the 22 Arab countries: A systematic review