Lista de obras - David Allsop - Dominio Público Uruguay

A demonstration of the advantages of immunostaining in the quantification of amyloid plaque deposits.

artículo científico publicado en 1989

A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson's disease.

scientific article published on January 2013

A monoclonal antibody to common acute lymphoblastic leukemia antigen (neutral endopeptidase) immunostains senile plaques in the brains of patients with Alzheimer's disease ⬇️

artículo científico publicado el 2 de enero de 1991

A novel retro-inverso peptide inhibitor reduces amyloid deposition, oxidation and inflammation and stimulates neurogenesis in the APPswe/PS1ΔE9 mouse model of Alzheimer's disease

artículo científico publicado en 2013

A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on beta-amyloid and alpha-synuclein

artículo científico publicado en 2006

Aggregation and metal-binding properties of mutant forms of the amyloid A beta peptide of Alzheimer's disease.

artículo científico publicado en 1996

Aggregation of Alzheimer's peptides

artículo científico publicado en 1994

Alzheimer's disease: correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome.

artículo científico publicado en 1999

Amyloid deposition as the central event in the aetiology of Alzheimer's disease ⬇️

artículo científico publicado el 1 de octubre de 1991

Amyloid β-peptide and Alzheimer's disease.

artículo científico publicado en 2014

Amyloidosis in Alzheimer's disease.

artículo científico publicado en 1994

An investigation into the lipid-binding properties of alpha-, beta- and gamma-synucleins in human brain and cerebrospinal fluid

scientific article published on 20 July 2007

An investigation into the proteolytic cleavage of Alzheimer amyloid precursor protein in PC-12 cells

artículo científico publicado en 1994

Apathy as a behavioural marker of cognitive impairment in Parkinson's disease: a longitudinal analysis

artículo científico publicado en 2019

Aβ levels in the jugular vein and high molecular weight Aβ oligomer levels in CSF can be used as biomarkers to indicate the anti-amyloid effect of IVIg for Alzheimer's disease

artículo científico publicado en 2017

Blood-based near-infrared spectroscopy for the rapid low-cost detection of Alzheimer's disease

scientific article published on 01 December 2018

CNS amyloid proteins in neurodegenerative diseases.

artículo científico publicado en 1988

Cerebral amyloid angiopathy as a cause of subarachnoid hemorrhage.

artículo científico publicado en 1990

Cerebrovascular amyloid in scrapie-affected sheep reacts with antibodies to prion protein.

artículo científico publicado en 1988

Combined use of CSF NfL and CSF TDP-43 improves diagnostic performance in ALS

scientific article published on 19 November 2019

Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106-126

artículo científico publicado en 2003

Copper-mediated formation of hydrogen peroxide from the amylin peptide: A novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?

article

Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease

artículo científico publicado en 2006

Designed Glycopeptidomimetics Disrupt Protein-Protein Interactions Mediating Amyloid β-Peptide Aggregation and Restore Neuroblastoma Cell Viability.

artículo científico publicado en 2016

Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's beta-amyloid peptide.

artículo científico publicado en 2008

Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies.

artículo científico publicado en 2009

Development & automation of a novel [(18)F]F prosthetic group, 2-[(18)F]-fluoro-3-pyridinecarboxaldehyde, and its application to an amino(oxy)-functionalised Aβ peptide

artículo científico publicado en 2016

Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease.

artículo científico publicado en 2010

Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes

artículo científico publicado en 2017

Diagnostic Biomarkers for Alzheimer's Disease Using Non-Invasive Specimens

scientific article published on 01 June 2020

Differential diagnosis of Alzheimer's disease using spectrochemical analysis of blood.

artículo científico publicado en 2017

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

artículo científico publicado en 1997

Donepezil for severe Alzheimer's disease

artículo científico publicado en 2006

Early senile plaques in Alzheimer's disease demonstrated by histochemistry, immunocytochemistry, and electron microscopy.

artículo científico publicado en 1990

Effect of aluminium on expression and processing of amyloid precursor protein

artículo científico publicado en 1996

Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide.

artículo científico publicado en 2011

Effects of different isoforms of apoE on aggregation of the α-synuclein protein implicated in Parkinson's disease

artículo científico publicado en 2016

Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid beta/A4 peptide.

artículo científico publicado en 1993

Endopeptidase 3.4.24.11 converts N-1-(R,S)carboxy-3-phenylpropyl-Ala-Ala-Phe-p-carboxyanilide into a potent inhibitor of angiotensin-converting enzyme.

artículo científico publicado en 1993

Evidence for the derivation of a peptide ligand from the amyloid beta-protein precursor of Alzheimer's disease.

artículo científico publicado en 1989

Evidence of amyloid beta-protein immunoreactive early plaque lesions in Down's syndrome brains

article

Fe(II)‐induced DNA damage in α‐synuclein‐transfected human dopaminergic BE(2)‐M17 neuroblastoma cells: detection by the Comet assay ⬇️

artículo científico publicado el 1 de noviembre de 2003

Fibrillogenesis of beta-amyloid

artículo científico publicado en 1998

Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease

artículo científico publicado en 2002

Galantamine inhibits beta-amyloid aggregation and cytotoxicity

artículo científico publicado en 2009

Gelatinase A not alpha-secretase?

artículo científico publicado en 1994

Gerstmann-Sträussler-Scheinker disease showing beta-protein type cerebellar and cerebral amyloid angiopathy

scientific article published on 01 January 1994

High-molecular-weight beta-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

artículo científico publicado en 2010

Human IMR-32 neuroblastoma cells as a model cell line in Alzheimer's disease research.

artículo científico publicado en 1994

Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia.

artículo científico publicado en 2005

Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis

scientific article published on 07 November 2008

Increased levels of plasma total tau in adult Down syndrome.

artículo científico publicado en 2017

Inflammatory mechanisms in Alzheimer's disease.

artículo científico publicado en 1994

Inherited frontotemporal dementia in nine British families associated with intronic mutations in the tau gene.

artículo científico

Liposome delivery systems for the treatment of Alzheimer's disease

scholarly article by Callum Ross et al published 12 December 2018 in International Journal of Nanomedicine

Magnetite pollution nanoparticles in the human brain

artículo científico publicado en 2016

Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease.

artículo científico publicado en 2008

Monoclonal antibodies raised against a subsequence of senile plaque core protein react with plaque cores, plaque periphery and cerebrovascular amyloid in Alzheimer's disease

artículo científico publicado en 1986

Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases. An immunohistochemical study using amyloid beta-protein antibody.

artículo científico publicado en 1989

New evidence that the Alzheimer beta-amyloid peptide does not spontaneously form free radicals: an ESR study using a series of spin-traps.

artículo científico publicado en 2001

Parkinson disease: Progress towards a molecular biomarker for Parkinson disease

artículo científico publicado en 2010

Phosphorylated α-synuclein as a potential biomarker for Parkinson's disease and related disorders

artículo científico publicado en 2012

Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease

artículo científico publicado en 2011

Pick's disease is associated with mutations in the tau gene

artículo científico publicado en 2000

Plasma amyloid-β concentrations in Alzheimer's disease: an alternative hypothesis

artículo científico publicado en 2006

Plasma neurofilament light chain: A potential prognostic biomarker of dementia in adult Down syndrome patients

artículo científico publicado en 2019

Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration

artículo científico publicado en 2009

Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies.

artículo científico publicado en 2011

Presenilins--in search of functionality.

artículo científico publicado en 1998

Quantification of beta A4 protein deposition in the medial temporal lobe: a comparison of Alzheimer's disease and senile dementia of the Lewy body type

artículo científico publicado el 3 de agosto de 1992

Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer's disease and down syndrome.

artículo científico publicado en 2017

Quantitative differences in the deposition of beta A4 protein in the sulci and gyri of frontal and temporal isocortex in Alzheimer's disease

artículo científico publicado en 1992

Quinacrine acts as an antioxidant and reduces the toxicity of the prion peptide PrP106-126.

artículo científico publicado en 2003

Raman Spectroscopy to Diagnose Alzheimer's Disease and Dementia with Lewy Bodies in Blood

artículo científico publicado en 2018

Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer's Aβ peptide

artículo científico publicado en 2016

Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks beta/A4 amyloid immunoreactivity

artículo científico publicado en 1993

Self-Assembly and Anti-Amyloid Cytotoxicity Activity of Amyloid beta Peptide Derivatives.

artículo científico publicado en 2017

TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's syndrome: association with age, hippocampal sclerosis and clinical phenotype

artículo científico publicado en 2011

TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration

artículo científico publicado en 2008

The amylin peptide implicated in type 2 diabetes stimulates copper-mediated carbonyl group and ascorbate radical formation.

artículo científico publicado en 2011

The immunoreactive profile at the N-terminal region of A beta 1-39/40 but not A beta 1-42 changes with transition from monomer/dimer to further peptide aggregates

scientific article published on 01 December 1995

The isolation and amino acid composition of senile plaque core protein.

artículo científico publicado en 1983

Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation.

artículo científico publicado en 2014

Utilization of a multiple antigenic peptide as a calibration standard in the BAN50 single antibody sandwich ELISA for Aβ oligomers

artículo científico publicado en 2012

Variability of beta-amyloid protein deposited lesions in Down's syndrome brains.

artículo científico publicado en 1994

alpha-Synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro

artículo científico publicado en 2001

α-Synuclein Interacts with Lipoproteins in Plasma.

artículo científico publicado en 2017

β(A4)-amyloid protein and parkinsonian-dementia complex of Guam ⬇️

artículo científico publicado el 5 de enero de 1991

β-Hairpin mimics containing a piperidine-pyrrolidine scaffold modulate the β-amyloid aggregation process preserving the monomer species.

artículo científico publicado en 2016

β-amyloid fibrils in Alzheimer disease are not inert when bound to copper ions but can degrade hydrogen peroxide and generate reactive oxygen species.

artículo científico publicado en 2014

Lista de obras de David Allsop

A demonstration of the advantages of immunostaining in the quantification of amyloid plaque deposits.

A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson's disease.

A monoclonal antibody to common acute lymphoblastic leukemia antigen (neutral endopeptidase) immunostains senile plaques in the brains of patients with Alzheimer's disease ⬇️

A novel retro-inverso peptide inhibitor reduces amyloid deposition, oxidation and inflammation and stimulates neurogenesis in the APPswe/PS1ΔE9 mouse model of Alzheimer's disease

A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on beta-amyloid and alpha-synuclein

Aggregation and metal-binding properties of mutant forms of the amyloid A beta peptide of Alzheimer's disease.

Aggregation of Alzheimer's peptides

Alzheimer's disease: correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome.

Amyloid deposition as the central event in the aetiology of Alzheimer's disease ⬇️

Amyloid β-peptide and Alzheimer's disease.

Amyloidosis in Alzheimer's disease.

An investigation into the lipid-binding properties of alpha-, beta- and gamma-synucleins in human brain and cerebrospinal fluid

An investigation into the proteolytic cleavage of Alzheimer amyloid precursor protein in PC-12 cells

Apathy as a behavioural marker of cognitive impairment in Parkinson's disease: a longitudinal analysis

Aβ levels in the jugular vein and high molecular weight Aβ oligomer levels in CSF can be used as biomarkers to indicate the anti-amyloid effect of IVIg for Alzheimer's disease

Blood-based near-infrared spectroscopy for the rapid low-cost detection of Alzheimer's disease

CNS amyloid proteins in neurodegenerative diseases.

Cerebral amyloid angiopathy as a cause of subarachnoid hemorrhage.

Cerebrovascular amyloid in scrapie-affected sheep reacts with antibodies to prion protein.

Combined use of CSF NfL and CSF TDP-43 improves diagnostic performance in ALS

Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106-126

Copper-mediated formation of hydrogen peroxide from the amylin peptide: A novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?

Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease

Designed Glycopeptidomimetics Disrupt Protein-Protein Interactions Mediating Amyloid β-Peptide Aggregation and Restore Neuroblastoma Cell Viability.

Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's beta-amyloid peptide.

Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies.

Development & automation of a novel [(18)F]F prosthetic group, 2-[(18)F]-fluoro-3-pyridinecarboxaldehyde, and its application to an amino(oxy)-functionalised Aβ peptide

Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease.

Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes

Diagnostic Biomarkers for Alzheimer's Disease Using Non-Invasive Specimens

Differential diagnosis of Alzheimer's disease using spectrochemical analysis of blood.

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

Donepezil for severe Alzheimer's disease

Early senile plaques in Alzheimer's disease demonstrated by histochemistry, immunocytochemistry, and electron microscopy.

Effect of aluminium on expression and processing of amyloid precursor protein

Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide.

Effects of different isoforms of apoE on aggregation of the α-synuclein protein implicated in Parkinson's disease

Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid beta/A4 peptide.

Endopeptidase 3.4.24.11 converts N-1-(R,S)carboxy-3-phenylpropyl-Ala-Ala-Phe-p-carboxyanilide into a potent inhibitor of angiotensin-converting enzyme.

Evidence for the derivation of a peptide ligand from the amyloid beta-protein precursor of Alzheimer's disease.

Evidence of amyloid beta-protein immunoreactive early plaque lesions in Down's syndrome brains

Fe(II)‐induced DNA damage in α‐synuclein‐transfected human dopaminergic BE(2)‐M17 neuroblastoma cells: detection by the Comet assay ⬇️

Fibrillogenesis of beta-amyloid

Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease

Galantamine inhibits beta-amyloid aggregation and cytotoxicity

Gelatinase A not alpha-secretase?

Gerstmann-Sträussler-Scheinker disease showing beta-protein type cerebellar and cerebral amyloid angiopathy

High-molecular-weight beta-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

Human IMR-32 neuroblastoma cells as a model cell line in Alzheimer's disease research.

Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia.

Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis

Increased levels of plasma total tau in adult Down syndrome.

Inflammatory mechanisms in Alzheimer's disease.

Inherited frontotemporal dementia in nine British families associated with intronic mutations in the tau gene.

Liposome delivery systems for the treatment of Alzheimer's disease

Magnetite pollution nanoparticles in the human brain

Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease.

Monoclonal antibodies raised against a subsequence of senile plaque core protein react with plaque cores, plaque periphery and cerebrovascular amyloid in Alzheimer's disease

Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases. An immunohistochemical study using amyloid beta-protein antibody.

New evidence that the Alzheimer beta-amyloid peptide does not spontaneously form free radicals: an ESR study using a series of spin-traps.

Parkinson disease: Progress towards a molecular biomarker for Parkinson disease

Phosphorylated α-synuclein as a potential biomarker for Parkinson's disease and related disorders

Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease

Pick's disease is associated with mutations in the tau gene

Plasma amyloid-β concentrations in Alzheimer's disease: an alternative hypothesis

Plasma neurofilament light chain: A potential prognostic biomarker of dementia in adult Down syndrome patients

Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration

Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies.

Presenilins--in search of functionality.

Quantification of beta A4 protein deposition in the medial temporal lobe: a comparison of Alzheimer's disease and senile dementia of the Lewy body type

Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer's disease and down syndrome.

Quantitative differences in the deposition of beta A4 protein in the sulci and gyri of frontal and temporal isocortex in Alzheimer's disease

Quinacrine acts as an antioxidant and reduces the toxicity of the prion peptide PrP106-126.

Raman Spectroscopy to Diagnose Alzheimer's Disease and Dementia with Lewy Bodies in Blood

Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer's Aβ peptide

Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks beta/A4 amyloid immunoreactivity

Self-Assembly and Anti-Amyloid Cytotoxicity Activity of Amyloid beta Peptide Derivatives.

TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's syndrome: association with age, hippocampal sclerosis and clinical phenotype

TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration