Lista de obras - Patrick M Boyle - Dominio Público Uruguay

"Beauty is a light in the heart": the transformative potential of optogenetics for clinical applications in cardiovascular medicine.

artículo científico publicado en 2014

A comprehensive multiscale framework for simulating optogenetics in the heart.

artículo científico publicado en 2013

A comprehensive, multiscale framework for evaluation of arrhythmias arising from cell therapy in the whole post-myocardial infarcted heart

scientific article published on 25 June 2019

Advances in modeling ventricular arrhythmias: from mechanisms to the clinic.

artículo científico

An intuitive safety factor for cardiac propagation.

artículo científico publicado en 2010

Arrhythmogenesis by single ectopic beats originating in the Purkinje system.

artículo científico publicado en 2010

Arrhythmogenic mechanisms of the Purkinje system during electric shocks: a modeling study.

artículo científico publicado en 2009

Behaviour of the purkinje system during defibrillation-strength shocks

artículo científico publicado en 2007

Comparing Reentrant Drivers Predicted by Image-Based Computational Modeling and Mapped by Electrocardiographic Imaging in Persistent Atrial Fibrillation.

artículo científico publicado en 2018

Computational cardiology: how computer simulations could be used to develop new therapies and advance existing ones

artículo científico publicado en 2012

Computational modeling identifies embolic stroke of undetermined source patients with potential arrhythmic substrate

artículo científico publicado en 2021

Computational modeling of cardiac optogenetics: Methodology overview & review of findings from simulations

artículo científico publicado en 2015

Computational rabbit models to investigate the initiation, perpetuation, and termination of ventricular arrhythmia.

artículo científico publicado en 2016

Dantrolene improves survival after ventricular fibrillation by mitigating impaired calcium handling in animal models

artículo científico publicado en 2014

Early somatic mosaicism is a rare cause of long-QT syndrome

scientific article published on 28 September 2016

Effects of the purkinje system and cardiac geometry on biventricular pacing: a model study.

artículo científico publicado en 2010

Exploring susceptibility to atrial and ventricular arrhythmias resulting from remodeling of the passive electrical properties in the heart: a simulation approach

artículo científico publicado en 2014

Feasibility of using patient-specific models and the "minimum cut" algorithm to predict optimal ablation targets for left atrial flutter

artículo científico publicado en 2016

Fibrosis, atrial fibrillation and stroke: clinical updates and emerging mechanistic models

artículo científico publicado en 2020

Fusion during entrainment of orthodromic reciprocating tachycardia is enhanced for basal pacing sites but diminished when pacing near Purkinje system end points.

artículo científico publicado en 2012

Image-based models of cardiac structure with applications in arrhythmia and defibrillation studies.

artículo científico publicado en 2009

Modeling the role of the coronary vasculature during external field stimulation.

artículo científico publicado en 2010

Modelling methodology of atrial fibrosis affects rotor dynamics and electrograms

artículo científico publicado en 2016

Opsin spectral sensitivity determines the effectiveness of optogenetic termination of ventricular fibrillation in the human heart: a simulation study.

artículo científico publicado en 2016

Optogenetic defibrillation terminates ventricular arrhythmia in mouse hearts and human simulations.

artículo científico publicado en 2016

Optogenetics-enabled assessment of viral gene and cell therapy for restoration of cardiac excitability.

artículo científico publicado en 2015

Optogenetics-enabled dynamic modulation of action potential duration in atrial tissue: feasibility of a novel therapeutic approach.

artículo científico publicado en 2014

Patient-derived models link re-entrant driver localization in atrial fibrillation to fibrosis spatial pattern

artículo científico publicado en 2016

Personalized virtual-heart technology for guiding the ablation of infarct-related ventricular tachycardia

artículo científico publicado en 2018

Propagating unstable wavelets in cardiac tissue

artículo científico publicado en 2012

Purkinje-mediated Effects in the Response of Quiescent Ventricles to Defibrillation Shocks

artículo científico publicado en 2009

Relationship Between Fibrosis Detected on Late Gadolinium-Enhanced Cardiac Magnetic Resonance and Re-Entrant Activity Assessed With Electrocardiographic Imaging in Human Persistent Atrial Fibrillation.

artículo científico publicado en 2017

See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort?

artículo científico

Sensitivity of reentrant driver localization to electrophysiological parameter variability in image-based computational models of persistent atrial fibrillation sustained by a fibrotic substrate.

artículo científico publicado en 2017

Simulations of reduced conduction reserve in the diabetic rat heart: response to uncoupling and reduced excitability.

artículo científico publicado en 2009

Sodium current reduction unmasks a structure-dependent substrate for arrhythmogenesis in the normal ventricles

artículo científico publicado en 2014

Stochastic spontaneous calcium release events trigger premature ventricular complexes by overcoming electrotonic load

artículo científico publicado en 2015

Termination of re-entrant atrial tachycardia via optogenetic stimulation with optimized spatial targeting: insights from computational models

artículo científico publicado en 2017

Translational applications of computational modelling for patients with cardiac arrhythmias

scientific article published on 10 December 2020

Lista de obras de Patrick M Boyle

"Beauty is a light in the heart": the transformative potential of optogenetics for clinical applications in cardiovascular medicine.

A comprehensive multiscale framework for simulating optogenetics in the heart.

A comprehensive, multiscale framework for evaluation of arrhythmias arising from cell therapy in the whole post-myocardial infarcted heart

Advances in modeling ventricular arrhythmias: from mechanisms to the clinic.

An intuitive safety factor for cardiac propagation.

Arrhythmogenesis by single ectopic beats originating in the Purkinje system.

Arrhythmogenic mechanisms of the Purkinje system during electric shocks: a modeling study.

Behaviour of the purkinje system during defibrillation-strength shocks

Comparing Reentrant Drivers Predicted by Image-Based Computational Modeling and Mapped by Electrocardiographic Imaging in Persistent Atrial Fibrillation.

Computational cardiology: how computer simulations could be used to develop new therapies and advance existing ones

Computational modeling identifies embolic stroke of undetermined source patients with potential arrhythmic substrate

Computational modeling of cardiac optogenetics: Methodology overview & review of findings from simulations

Computational rabbit models to investigate the initiation, perpetuation, and termination of ventricular arrhythmia.

Dantrolene improves survival after ventricular fibrillation by mitigating impaired calcium handling in animal models

Early somatic mosaicism is a rare cause of long-QT syndrome

Effects of the purkinje system and cardiac geometry on biventricular pacing: a model study.

Exploring susceptibility to atrial and ventricular arrhythmias resulting from remodeling of the passive electrical properties in the heart: a simulation approach

Feasibility of using patient-specific models and the "minimum cut" algorithm to predict optimal ablation targets for left atrial flutter

Fibrosis, atrial fibrillation and stroke: clinical updates and emerging mechanistic models

Fusion during entrainment of orthodromic reciprocating tachycardia is enhanced for basal pacing sites but diminished when pacing near Purkinje system end points.

Image-based models of cardiac structure with applications in arrhythmia and defibrillation studies.

Modeling the role of the coronary vasculature during external field stimulation.

Modelling methodology of atrial fibrosis affects rotor dynamics and electrograms

Opsin spectral sensitivity determines the effectiveness of optogenetic termination of ventricular fibrillation in the human heart: a simulation study.

Optogenetic defibrillation terminates ventricular arrhythmia in mouse hearts and human simulations.

Optogenetics-enabled assessment of viral gene and cell therapy for restoration of cardiac excitability.

Optogenetics-enabled dynamic modulation of action potential duration in atrial tissue: feasibility of a novel therapeutic approach.

Patient-derived models link re-entrant driver localization in atrial fibrillation to fibrosis spatial pattern

Personalized virtual-heart technology for guiding the ablation of infarct-related ventricular tachycardia

Propagating unstable wavelets in cardiac tissue

Purkinje-mediated Effects in the Response of Quiescent Ventricles to Defibrillation Shocks

Relationship Between Fibrosis Detected on Late Gadolinium-Enhanced Cardiac Magnetic Resonance and Re-Entrant Activity Assessed With Electrocardiographic Imaging in Human Persistent Atrial Fibrillation.

See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort?

Sensitivity of reentrant driver localization to electrophysiological parameter variability in image-based computational models of persistent atrial fibrillation sustained by a fibrotic substrate.

Simulations of reduced conduction reserve in the diabetic rat heart: response to uncoupling and reduced excitability.

Sodium current reduction unmasks a structure-dependent substrate for arrhythmogenesis in the normal ventricles

Stochastic spontaneous calcium release events trigger premature ventricular complexes by overcoming electrotonic load

Termination of re-entrant atrial tachycardia via optogenetic stimulation with optimized spatial targeting: insights from computational models

Translational applications of computational modelling for patients with cardiac arrhythmias